{"id":"https://openalex.org/W2577421348","doi":"https://doi.org/10.1109/bibm.2016.7822502","title":"Mining structural variants of Heduo12 using paired-end reads","display_name":"Mining structural variants of Heduo12 using paired-end reads","publication_year":2016,"publication_date":"2016-12-01","ids":{"openalex":"https://openalex.org/W2577421348","doi":"https://doi.org/10.1109/bibm.2016.7822502","mag":"2577421348"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2016.7822502","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2016.7822502","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072535452","display_name":"Huiqiang Jia","orcid":null},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiqiang Jia","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027649189","display_name":"Haicho Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haicho Wei","raw_affiliation_strings":["Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Changchun, China","institution_ids":["https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101769221","display_name":"Daming Zhu","orcid":"https://orcid.org/0000-0001-9395-7247"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daming Zhu","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100631336","display_name":"Jingjing Ma","orcid":"https://orcid.org/0000-0001-9011-3372"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jingjing Ma","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045705475","display_name":"Hai Yang","orcid":"https://orcid.org/0000-0001-5210-8468"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hai Yang","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100643241","display_name":"Ruizhi Wang","orcid":"https://orcid.org/0000-0002-2132-7657"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruizhi Wang","raw_affiliation_strings":["School of Computer Science and Technology, Shandong University, Jinan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Shandong University, Jinan, China","institution_ids":["https://openalex.org/I80143920"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108137566","display_name":"Xianzhong Feng","orcid":"https://orcid.org/0000-0002-7129-3731"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xianzhong Feng","raw_affiliation_strings":["Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Soybean Molecular Design Breeding, Chinese Academy of Sciences, Changchun, China","institution_ids":["https://openalex.org/I19820366"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10822659,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":null,"first_page":"111","last_page":"115"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10602","display_name":"Glycosylation and Glycoproteins Research","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6370319128036499},{"id":"https://openalex.org/keywords/structural-variation","display_name":"Structural variation","score":0.6178162097930908},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5801985263824463},{"id":"https://openalex.org/keywords/cover","display_name":"Cover (algebra)","score":0.5321385860443115},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4822829067707062},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4486442506313324},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3709890842437744},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.32292765378952026},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.17351087927818298},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1715366244316101},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10131257772445679},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08292821049690247}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6370319128036499},{"id":"https://openalex.org/C151020129","wikidata":"https://www.wikidata.org/wiki/Q7625067","display_name":"Structural variation","level":4,"score":0.6178162097930908},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5801985263824463},{"id":"https://openalex.org/C2780428219","wikidata":"https://www.wikidata.org/wiki/Q16952335","display_name":"Cover (algebra)","level":2,"score":0.5321385860443115},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4822829067707062},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4486442506313324},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3709890842437744},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.32292765378952026},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17351087927818298},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1715366244316101},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10131257772445679},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08292821049690247},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2016.7822502","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2016.7822502","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2016 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1592050624","https://openalex.org/W2000586119","https://openalex.org/W2049997041","https://openalex.org/W2065817684","https://openalex.org/W2101342813","https://openalex.org/W2103441770","https://openalex.org/W2111350087","https://openalex.org/W2123690878","https://openalex.org/W2131131179","https://openalex.org/W2132298698","https://openalex.org/W2139993758","https://openalex.org/W2143325524","https://openalex.org/W2146005104","https://openalex.org/W2150506261","https://openalex.org/W2154397429","https://openalex.org/W2169508919"],"related_works":["https://openalex.org/W4232403550","https://openalex.org/W623607250","https://openalex.org/W4245429118","https://openalex.org/W4205110281","https://openalex.org/W4212927854","https://openalex.org/W4211151614","https://openalex.org/W2043074282","https://openalex.org/W2203319208","https://openalex.org/W3193218983","https://openalex.org/W4306698144"],"abstract_inverted_index":{"In":[0],"this":[1],"paper,":[2],"we":[3,69],"devote":[4],"to":[5,24,48,76,102],"detect":[6],"those":[7,65,84],"deletions,":[8],"insertions":[9],"and":[10,42,96,107,118],"inversions,":[11],"in":[12,20],"total":[13],"of":[14,17,40,64,109],"three":[15],"kinds":[16],"structural":[18,56,67,80,88],"variations":[19],"Heidou12":[21],"genome":[22],"relative":[23],"Williams82":[25,47],"genome.":[26],"We":[27],"propose":[28,70],"two":[29],"sequencing":[30],"characteristic":[31],"based":[32,100],"probability":[33,53],"models,":[34],"which":[35],"use":[36,97],"the":[37,62],"paired-end":[38],"reads":[39,85],"Hedou12":[41],"their":[43],"mapping":[44],"distribution":[45],"on":[46,50,78],"evaluate":[49],"with":[51,90,116],"what":[52],"a":[54,71,98],"potential":[55,66,87],"variant":[57],"can":[58],"happen.":[59],"To":[60],"reduce":[61],"conflicts":[63],"variants,":[68],"set":[72],"cover":[73],"problem":[74],"model":[75],"formalize":[77],"finding":[79],"variants":[81,89],"covering":[82],"all":[83],"causing":[86],"as":[91,93],"high":[92],"possible":[94],"probabilities,":[95],"primal-dual":[99],"algorithm":[101,111],"solve":[103],"it.":[104],"The":[105],"efficiency":[106],"feasibility":[108],"our":[110],"are":[112],"verified":[113],"by":[114],"comparing":[115],"DELLY(version0.5.5)":[117],"LUMPY":[119],"(27.12.2014).":[120]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}