{"id":"https://openalex.org/W2208597264","doi":"https://doi.org/10.1109/bibm.2015.7359816","title":"A semantic approach for knowledge capture of MIcroRNA-Target gene interactions","display_name":"A semantic approach for knowledge capture of MIcroRNA-Target gene interactions","publication_year":2015,"publication_date":"2015-11-01","ids":{"openalex":"https://openalex.org/W2208597264","doi":"https://doi.org/10.1109/bibm.2015.7359816","mag":"2208597264"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2015.7359816","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2015.7359816","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://philpapers.org/archive/HUAASA.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103191466","display_name":"Jingshan Huang","orcid":"https://orcid.org/0000-0003-2408-2883"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jingshan Huang","raw_affiliation_strings":["School of Computing, University of South Alabama Mobile, Alabama, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computing, University of South Alabama Mobile, Alabama, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101814622","display_name":"Fernando Gutierrez","orcid":"https://orcid.org/0000-0002-7435-7673"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fernando Gutierrez","raw_affiliation_strings":["CIS Dept., University of Oregon, Eugene, Oregon, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIS Dept., University of Oregon, Eugene, Oregon, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066063885","display_name":"Dejing Dou","orcid":"https://orcid.org/0000-0001-7561-1672"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dejing Dou","raw_affiliation_strings":["CIS Dept., University of Oregon, Eugene, Oregon, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIS Dept., University of Oregon, Eugene, Oregon, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016349593","display_name":"Judith A. Blake","orcid":"https://orcid.org/0000-0001-8522-334X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judith A. Blake","raw_affiliation_strings":["The Jackson Laboratory, Maine, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory, Maine, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014696304","display_name":"Karen Eilbeck","orcid":"https://orcid.org/0000-0002-0831-6427"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Karen Eilbeck","raw_affiliation_strings":["School of Medicine, University of Utah Salt, Lake City, Utah, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, University of Utah Salt, Lake City, Utah, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005555412","display_name":"Darren A. Natale","orcid":"https://orcid.org/0000-0001-5809-9523"},"institutions":[{"id":"https://openalex.org/I2799903593","display_name":"Georgetown University Medical Center","ror":"https://ror.org/00hjz7x27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799903593"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Darren A. Natale","raw_affiliation_strings":["Georgetown University Medical Center, Washington, D.C., U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Georgetown University Medical Center, Washington, D.C., U.S.A","institution_ids":["https://openalex.org/I2799903593","https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051216244","display_name":"Barry Smith","orcid":"https://orcid.org/0000-0003-1384-116X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barry Smith","raw_affiliation_strings":["Dept. Philosophy, University at Buffalo, Buffalo, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. Philosophy, University at Buffalo, Buffalo, New York, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100599538","display_name":"Yu Lin","orcid":"https://orcid.org/0000-0003-2620-0345"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yu Lin","raw_affiliation_strings":["University of Miami, Miami, Florida, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Miami, Miami, Florida, U.S.A","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100460487","display_name":"Xiaowei Wang","orcid":"https://orcid.org/0000-0001-9447-4685"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xiaowei Wang","raw_affiliation_strings":["Washington University School of Medicine, St. Louis, Missouri, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University School of Medicine, St. Louis, Missouri, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008882614","display_name":"Zixing Liu","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zixing Liu","raw_affiliation_strings":["MCI, University of South Alabama Mobile, Alabama, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MCI, University of South Alabama Mobile, Alabama, U.S.A","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029461308","display_name":"Ming Tan","orcid":"https://orcid.org/0000-0001-6565-699X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ming Tan","raw_affiliation_strings":["MCI, University of South Alabama Mobile, Alabama, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MCI, University of South Alabama Mobile, Alabama, U.S.A","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053171726","display_name":"Alan Ruttenberg","orcid":"https://orcid.org/0000-0002-1604-3078"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alan Ruttenberg","raw_affiliation_strings":["Dental Medicine, University at Buffalo, Buffalo, New York, U.S.A"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental Medicine, University at Buffalo, Buffalo, New York, U.S.A","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5103191466"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.5058,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.82727582,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"6","issue":null,"first_page":"975","last_page":"982"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10181","display_name":"Natural Language Processing Techniques","score":0.9771999716758728,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7035800814628601},{"id":"https://openalex.org/keywords/ontology","display_name":"Ontology","score":0.6419365406036377},{"id":"https://openalex.org/keywords/gene-ontology","display_name":"Gene ontology","score":0.542593240737915},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.5235105156898499},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.500751256942749},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3212006688117981},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.20315194129943848},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1292392611503601}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7035800814628601},{"id":"https://openalex.org/C25810664","wikidata":"https://www.wikidata.org/wiki/Q44325","display_name":"Ontology","level":2,"score":0.6419365406036377},{"id":"https://openalex.org/C2987395477","wikidata":"https://www.wikidata.org/wiki/Q135085","display_name":"Gene ontology","level":4,"score":0.542593240737915},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5235105156898499},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.500751256942749},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3212006688117981},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20315194129943848},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1292392611503601},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/bibm.2015.7359816","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2015.7359816","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},{"id":"pmh:oai:philarchive.org/rec/HUAASA","is_oa":true,"landing_page_url":"https://philarchive.org/rec/HUAASA","pdf_url":"https://philpapers.org/archive/HUAASA.pdf","source":{"id":"https://openalex.org/S4306402130","display_name":"PhilPapers (PhilPapers Foundation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:philpapers.org/rec/HUAASA","is_oa":false,"landing_page_url":"https://philpapers.org/rec/HUAASA","pdf_url":null,"source":{"id":"https://openalex.org/S4306402131","display_name":"PhilPapers (PhilPapers Foundation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:philarchive.org/rec/HUAASA","is_oa":true,"landing_page_url":"https://philarchive.org/rec/HUAASA","pdf_url":"https://philpapers.org/archive/HUAASA.pdf","source":{"id":"https://openalex.org/S4306402130","display_name":"PhilPapers (PhilPapers Foundation)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.5,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2208597264.pdf"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1516264322","https://openalex.org/W1551304708","https://openalex.org/W1572535120","https://openalex.org/W1580895464","https://openalex.org/W1745004017","https://openalex.org/W1965078122","https://openalex.org/W1992178442","https://openalex.org/W1998002050","https://openalex.org/W2026732830","https://openalex.org/W2044231962","https://openalex.org/W2056168203","https://openalex.org/W2061231608","https://openalex.org/W2067812505","https://openalex.org/W2079471715","https://openalex.org/W2087065641","https://openalex.org/W2103017472","https://openalex.org/W2103260426","https://openalex.org/W2108177663","https://openalex.org/W2123171788","https://openalex.org/W2145969913","https://openalex.org/W2162965868","https://openalex.org/W2185907055","https://openalex.org/W2988119170","https://openalex.org/W6633164484","https://openalex.org/W6637600892"],"related_works":["https://openalex.org/W2737319532","https://openalex.org/W3151405604","https://openalex.org/W2565797512","https://openalex.org/W2003333417","https://openalex.org/W2050308539","https://openalex.org/W2793648706","https://openalex.org/W3043187607","https://openalex.org/W2019096591","https://openalex.org/W3032012916","https://openalex.org/W1744006947"],"abstract_inverted_index":{"Research":[0],"has":[1],"indicated":[2],"that":[3,66],"microRNAs":[4],"(miRNAs),":[5],"a":[6,45,85,132],"special":[7],"class":[8],"of":[9,50,127,138],"non-coding":[10],"RNAs":[11],"(ncRNAs),":[12],"can":[13,72],"perform":[14],"important":[15],"roles":[16],"in":[17,76,107,118],"different":[18],"biological":[19],"and":[20,40,48,57,103,123],"pathological":[21],"processes.":[22],"miRNAs'":[23,51],"functions":[24],"are":[25,67],"realized":[26],"by":[27],"regulating":[28],"their":[29],"respective":[30],"target":[31],"genes":[32],"(targets).":[33],"It":[34],"is":[35],"thus":[36],"critical":[37],"to":[38,95,130],"identify":[39],"analyze":[41],"miRNA-target":[42,139],"interactions":[43],"for":[44,91,135],"better":[46],"understanding":[47],"delineation":[49],"functions.":[52],"However,":[53],"conventional":[54],"knowledge":[55,136],"discovery":[56],"acquisition":[58],"methods":[59],"have":[60],"many":[61],"limitations.":[62],"Fortunately,":[63],"semantic":[64,133],"technologies":[65],"based":[68],"on":[69],"domain":[70],"ontologies":[71],"render":[73],"great":[74],"assistance":[75],"this":[77],"regard.":[78],"In":[79],"our":[80,115],"previous":[81],"investigations,":[82],"we":[83],"developed":[84],"miRNA":[86,109],"domain-specific":[87],"application":[88,126],"ontology,":[89],"Ontology":[90],"MIcroRNA":[92],"Target":[93],"(OMIT),":[94],"provide":[96],"the":[97,108,119,125,128],"community":[98],"with":[99],"common":[100],"data":[101,104],"elements":[102],"exchange":[105],"standards":[106],"research.":[110],"This":[111],"paper":[112],"describes":[113],"(1)":[114],"continuing":[116],"efforts":[117],"OMIT":[120,129],"ontology":[121],"development":[122],"(2)":[124],"enable":[131],"approach":[134],"capture":[137],"interactions.":[140]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":5}],"updated_date":"2026-05-14T08:36:36.166977","created_date":"2025-10-10T00:00:00"}
