{"id":"https://openalex.org/W1995472325","doi":"https://doi.org/10.1109/bibm.2014.6999248","title":"Ant colony optimisation of decision trees for the detection of gene-gene interactions","display_name":"Ant colony optimisation of decision trees for the detection of gene-gene interactions","publication_year":2014,"publication_date":"2014-11-01","ids":{"openalex":"https://openalex.org/W1995472325","doi":"https://doi.org/10.1109/bibm.2014.6999248","mag":"1995472325"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2014.6999248","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2014.6999248","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105350545","display_name":"Emmanuel Sapin","orcid":"https://orcid.org/0000-0002-7188-3715"},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. Sapin","raw_affiliation_strings":["College of Engineering, Mathematics and Physical Sciences, University of Exeter, UK","College of Engineering, Mathematics and Physical Sciences & Exeter Medical School, University of Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences, University of Exeter, UK","institution_ids":["https://openalex.org/I23923803"]},{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences & Exeter Medical School, University of Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058871746","display_name":"Edward Keedwell","orcid":"https://orcid.org/0000-0003-3650-6487"},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"E. Keedwell","raw_affiliation_strings":["College of Engineering, Mathematics and Physical Sciences, University of Exeter, UK","College of Engineering, Mathematics and Physical Sciences & Exeter Medical School, University of Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences, University of Exeter, UK","institution_ids":["https://openalex.org/I23923803"]},{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences & Exeter Medical School, University of Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025710476","display_name":"Timothy M. Frayling","orcid":"https://orcid.org/0000-0001-8362-2603"},"institutions":[{"id":"https://openalex.org/I23923803","display_name":"University of Exeter","ror":"https://ror.org/03yghzc09","country_code":"GB","type":"education","lineage":["https://openalex.org/I23923803"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"T. Frayling","raw_affiliation_strings":["College of Engineering, Mathematics and Physical Sciences, University of Exeter, UK","College of Engineering, Mathematics and Physical Sciences & Exeter Medical School, University of Exeter, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences, University of Exeter, UK","institution_ids":["https://openalex.org/I23923803"]},{"raw_affiliation_string":"College of Engineering, Mathematics and Physical Sciences & Exeter Medical School, University of Exeter, UK","institution_ids":["https://openalex.org/I23923803"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I23923803"],"apc_list":null,"apc_paid":null,"fwci":4.8224,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.93676069,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"57","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contingency-table","display_name":"Contingency table","score":0.665497362613678},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.5511469841003418},{"id":"https://openalex.org/keywords/decision-tree","display_name":"Decision tree","score":0.5318996906280518},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5185380578041077},{"id":"https://openalex.org/keywords/ant-colony","display_name":"Ant colony","score":0.5185071229934692},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5180973410606384},{"id":"https://openalex.org/keywords/ant-colony-optimization-algorithms","display_name":"Ant colony optimization algorithms","score":0.5111194252967834},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4761198163032532},{"id":"https://openalex.org/keywords/table","display_name":"Table (database)","score":0.44936808943748474},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.44814324378967285},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.4369122385978699},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4063875079154968},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3727734088897705},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.30828624963760376},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2689080536365509},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.2116818130016327},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.20629209280014038},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.13642233610153198},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.10727697610855103}],"concepts":[{"id":"https://openalex.org/C91998498","wikidata":"https://www.wikidata.org/wiki/Q1541178","display_name":"Contingency table","level":2,"score":0.665497362613678},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5511469841003418},{"id":"https://openalex.org/C84525736","wikidata":"https://www.wikidata.org/wiki/Q831366","display_name":"Decision tree","level":2,"score":0.5318996906280518},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5185380578041077},{"id":"https://openalex.org/C60891933","wikidata":"https://www.wikidata.org/wiki/Q796575","display_name":"Ant colony","level":3,"score":0.5185071229934692},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5180973410606384},{"id":"https://openalex.org/C40128228","wikidata":"https://www.wikidata.org/wiki/Q460851","display_name":"Ant colony optimization algorithms","level":2,"score":0.5111194252967834},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4761198163032532},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.44936808943748474},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.44814324378967285},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.4369122385978699},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4063875079154968},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3727734088897705},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.30828624963760376},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2689080536365509},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.2116818130016327},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.20629209280014038},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.13642233610153198},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.10727697610855103}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2014.6999248","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2014.6999248","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.7699999809265137}],"awards":[{"id":"https://openalex.org/G4301784705","display_name":null,"funder_award_id":"EP/J007439/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"}],"funders":[{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W17054689","https://openalex.org/W1539593569","https://openalex.org/W1546094903","https://openalex.org/W1597994084","https://openalex.org/W1917985521","https://openalex.org/W1973671916","https://openalex.org/W1973948212","https://openalex.org/W1981723690","https://openalex.org/W1987182818","https://openalex.org/W1993106768","https://openalex.org/W2014469644","https://openalex.org/W2033351559","https://openalex.org/W2036942421","https://openalex.org/W2043192290","https://openalex.org/W2048755332","https://openalex.org/W2085088301","https://openalex.org/W2087200541","https://openalex.org/W2088276287","https://openalex.org/W2097660065","https://openalex.org/W2113784410","https://openalex.org/W2129961269","https://openalex.org/W2131878646","https://openalex.org/W2134783591","https://openalex.org/W2141642891","https://openalex.org/W2150577353","https://openalex.org/W2154486810","https://openalex.org/W2154572047","https://openalex.org/W2158416439","https://openalex.org/W2161630867","https://openalex.org/W2167904191","https://openalex.org/W2171698295","https://openalex.org/W2282092107","https://openalex.org/W2911964244","https://openalex.org/W4233735624","https://openalex.org/W4299689471"],"related_works":["https://openalex.org/W2347951034","https://openalex.org/W2388326823","https://openalex.org/W2366876790","https://openalex.org/W2381829748","https://openalex.org/W2071981049","https://openalex.org/W2244460820","https://openalex.org/W2109336245","https://openalex.org/W2511325427","https://openalex.org/W2392795382","https://openalex.org/W2379177376"],"abstract_inverted_index":{"In":[0],"this":[1],"paper":[2],"ant":[3],"colony":[4],"optimisation":[5],"is":[6,21,43],"used":[7,22],"to":[8,23],"derive":[9],"near-optimal":[10],"interactions":[11],"between":[12],"a":[13,35,54,58],"number":[14,59],"of":[15,27,60],"single":[16,28,62],"nucleotide":[17,29,63],"polymorphisms.":[18],"This":[19],"approach":[20],"discover":[24],"small":[25],"numbers":[26],"polymorphisms":[30,64],"that":[31,45],"are":[32],"combined":[33],"into":[34],"decision":[36],"tree":[37],"or":[38],"contingency":[39],"table":[40],"model.":[41],"It":[42],"shown":[44],"these":[46],"two":[47],"models":[48],"can":[49],"be":[50],"highly":[51],"discriminatory":[52],"from":[53],"statistical":[55],"perspective":[56],"and":[57],"the":[61],"discovered":[65],"have":[66],"been":[67],"identified":[68],"previously":[69],"in":[70],"large":[71],"genome-wide":[72],"association":[73],"studies.":[74]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}
