{"id":"https://openalex.org/W1975936891","doi":"https://doi.org/10.1109/bibm.2013.6732547","title":"Characterisation of protein-protein interaction network base on ℓ1-norm optimisation","display_name":"Characterisation of protein-protein interaction network base on ℓ1-norm optimisation","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W1975936891","doi":"https://doi.org/10.1109/bibm.2013.6732547","mag":"1975936891"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2013.6732547","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2013.6732547","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008902922","display_name":"Benjamin Yee Shing Li","orcid":"https://orcid.org/0000-0002-6243-8724"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":true,"raw_author_name":"Benjamin Yee Shing Li","raw_affiliation_strings":["City University of Hong Kong, Kowloon, HK","Dept. of Electron. Eng., City Univ. of Hong Kong, Hong Kong, , China"],"affiliations":[{"raw_affiliation_string":"City University of Hong Kong, Kowloon, HK","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Dept. of Electron. Eng., City Univ. of Hong Kong, Hong Kong, , China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018500010","display_name":"L.F. Yeung","orcid":"https://orcid.org/0000-0001-6462-7855"},"institutions":[{"id":"https://openalex.org/I168719708","display_name":"City University of Hong Kong","ror":"https://ror.org/03q8dnn23","country_code":"HK","type":"education","lineage":["https://openalex.org/I168719708"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Lam Fat Yeung","raw_affiliation_strings":["Department of Electronic Engineering, The City University of Hong Kong, Hong Kong","Dept. of Electron. Eng., City Univ. of Hong Kong, Hong Kong, , China"],"affiliations":[{"raw_affiliation_string":"Department of Electronic Engineering, The City University of Hong Kong, Hong Kong","institution_ids":["https://openalex.org/I168719708"]},{"raw_affiliation_string":"Dept. of Electron. Eng., City Univ. of Hong Kong, Hong Kong, , China","institution_ids":["https://openalex.org/I168719708"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054304362","display_name":"Choujun Zhan","orcid":"https://orcid.org/0000-0002-1445-3559"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Choujun Zhan","raw_affiliation_strings":["Department of Electronics Communication and Software Engineering, Nanfang College of-Sun Yat-Scn University, China","Dept. of Electron. Commun. & Software Eng., Nanfang Coll. of Sun Yat-Sen Univ., Nanfang, China"],"affiliations":[{"raw_affiliation_string":"Department of Electronics Communication and Software Engineering, Nanfang College of-Sun Yat-Scn University, China","institution_ids":[]},{"raw_affiliation_string":"Dept. of Electron. Commun. & Software Eng., Nanfang Coll. of Sun Yat-Sen Univ., Nanfang, China","institution_ids":["https://openalex.org/I157773358"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001818611","display_name":"Genke Yang","orcid":"https://orcid.org/0000-0003-3492-0211"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Genke Yang","raw_affiliation_strings":["Department of Automation, Shanghai Jiao Tong University, Shanghai","[Department of Automation, Shanghai Jiao Tong University, Shanghai, China.]"],"affiliations":[{"raw_affiliation_string":"Department of Automation, Shanghai Jiao Tong University, Shanghai","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"[Department of Automation, Shanghai Jiao Tong University, Shanghai, China.]","institution_ids":["https://openalex.org/I183067930"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5008902922"],"corresponding_institution_ids":["https://openalex.org/I168719708"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04816902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":null,"first_page":"509","last_page":"512"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9926000237464905,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.7051606178283691},{"id":"https://openalex.org/keywords/herpes-simplex-virus","display_name":"Herpes simplex virus","score":0.5790041089057922},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5675944089889526},{"id":"https://openalex.org/keywords/simplex","display_name":"Simplex","score":0.47031036019325256},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.4417421519756317},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37971752882003784},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.37605905532836914},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3752422332763672},{"id":"https://openalex.org/keywords/topology","display_name":"Topology (electrical circuits)","score":0.36305391788482666},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3526897728443146},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3123052716255188},{"id":"https://openalex.org/keywords/virus","display_name":"Virus","score":0.27840524911880493},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.2606229782104492},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.19431999325752258},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.13322928547859192},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1221432089805603}],"concepts":[{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.7051606178283691},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.5790041089057922},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5675944089889526},{"id":"https://openalex.org/C62438384","wikidata":"https://www.wikidata.org/wiki/Q331350","display_name":"Simplex","level":2,"score":0.47031036019325256},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.4417421519756317},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37971752882003784},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.37605905532836914},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3752422332763672},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.36305391788482666},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3526897728443146},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3123052716255188},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.27840524911880493},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.2606229782104492},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.19431999325752258},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.13322928547859192},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1221432089805603}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2013.6732547","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2013.6732547","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1615495572","https://openalex.org/W1984249061","https://openalex.org/W1994803330","https://openalex.org/W2013520054","https://openalex.org/W2064786382","https://openalex.org/W2096801391","https://openalex.org/W2097706568","https://openalex.org/W2101181377","https://openalex.org/W2101998831","https://openalex.org/W2106202847","https://openalex.org/W2134711219","https://openalex.org/W2136387422","https://openalex.org/W2146997276","https://openalex.org/W2160144441","https://openalex.org/W2161062388","https://openalex.org/W2161997479","https://openalex.org/W2166680964","https://openalex.org/W2222512263","https://openalex.org/W2493109494","https://openalex.org/W4211083314","https://openalex.org/W4250589301","https://openalex.org/W6674647444","https://openalex.org/W6683775605","https://openalex.org/W6683906321"],"related_works":["https://openalex.org/W2063021680","https://openalex.org/W4255837520","https://openalex.org/W2357922472","https://openalex.org/W2384278689","https://openalex.org/W2387011115","https://openalex.org/W2563365141","https://openalex.org/W2386777115","https://openalex.org/W4234808182","https://openalex.org/W2382043075","https://openalex.org/W2809151339"],"abstract_inverted_index":{"Knowledge":[0],"of":[1,9,14,18,37,65,70,90,101,133,170],"interactions":[2],"between":[3],"proteins":[4],"is":[5,21,46,82,95],"an":[6,53,71],"importance":[7],"piece":[8],"information":[10,169],"on":[11],"the":[12,19,26,58,78,86,98,134,148,153,171],"understanding":[13],"cellular":[15],"mechanism.":[16],"One":[17],"challenges":[20],"to":[22,97],"quantify":[23],"how":[24],"similar":[25],"two":[27],"protein-protein":[28],"interaction":[29],"(PPI)":[30],"networks.":[31],"To":[32,74,84],"provide":[33],"a":[34,40,62],"candidate":[35],"solution":[36],"this":[38,76,91,128],"problem,":[39,77],"distance":[41,49,92,149],"measure":[42,50,69,150],"for":[43],"PPI":[44,99,130,172],"networks":[45,100],"proposed.":[47],"This":[48],"involves":[51],"solving":[52],"optimisation":[54],"problem":[55],"with":[56],"which":[57],"objective":[59],"function":[60],"being":[61],"weighted":[63],"sum":[64],"topological":[66,168],"and":[67,88,120,139],"biological":[68],"alignment":[72],"respectively.":[73],"solve":[75],"projected":[79],"subgradient":[80],"method":[81],"employed.":[83],"illustrate":[85],"performance":[87],"usage":[89],"measure,":[93],"it":[94],"applied":[96],"herpesvirus":[102,118,164],"family.":[103],"Five":[104],"herpesviruses:":[105],"EpsteinBarr":[106],"virus":[107,111,123],"(EBV),":[108],"Herpes":[109],"simplex":[110],"(HSV),":[112],"Mouse":[113],"Cytomegalovirus":[114],"(mCMV),":[115],"Kaposi's":[116],"sarcoma-associated":[117],"(KSHV)":[119],"Varicella":[121],"zoster":[122],"(VZV)":[124],"are":[125,137],"considered":[126],"in":[127],"paper.":[129],"network":[131],"distances":[132],"five":[135],"her-pesviruses":[136],"computed":[138],"visualized":[140],"using":[141],"multidimensional":[142],"scaling":[143],"(MDS).":[144],"Results":[145],"show":[146],"that":[147],"can":[151,161],"reflect":[152],"dissimilarity":[154],"among":[155],"organisms.":[156],"In":[157],"addition":[158],"our":[159],"algorithm":[160],"also":[162],"separate":[163],"subfamilies":[165],"given":[166],"only":[167],"network.":[173]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}