{"id":"https://openalex.org/W1963487661","doi":"https://doi.org/10.1109/bibm.2013.6732477","title":"Unveiling the dynamics in RNA epigenetic regulations","display_name":"Unveiling the dynamics in RNA epigenetic regulations","publication_year":2013,"publication_date":"2013-12-01","ids":{"openalex":"https://openalex.org/W1963487661","doi":"https://doi.org/10.1109/bibm.2013.6732477","mag":"1963487661"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2013.6732477","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2013.6732477","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062986831","display_name":"Jia Meng","orcid":"https://orcid.org/0000-0003-3455-205X"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Meng","raw_affiliation_strings":["Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, China","Dept. of Biol. Sci., Xi'an Jiaotong-Liverpool Univ., Suzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"Dept. of Biol. Sci., Xi'an Jiaotong-Liverpool Univ., Suzhou, China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102014287","display_name":"Xiaodong Cui","orcid":"https://orcid.org/0000-0001-5023-4890"},"institutions":[{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaodong Cui","raw_affiliation_strings":["Department of ECE, University of Texas, San Antonio, TX, USA","Dept. of ECE, Univ. of Texas at San Antonio, San Antonio, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of ECE, University of Texas, San Antonio, TX, USA","institution_ids":["https://openalex.org/I45438204"]},{"raw_affiliation_string":"Dept. of ECE, Univ. of Texas at San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I45438204"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113566766","display_name":"Hui Liu","orcid":"https://orcid.org/0000-0001-8845-4813"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Liu","raw_affiliation_strings":["School of Information and Electrical Engineering, China University of Mining and Technology, Xuzhou, China","Sch. of Inf. & Electr. Eng., China Univ. of Min. & Technol., Xuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information and Electrical Engineering, China University of Mining and Technology, Xuzhou, China","institution_ids":["https://openalex.org/I25757504"]},{"raw_affiliation_string":"Sch. of Inf. & Electr. Eng., China Univ. of Min. & Technol., Xuzhou, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100351875","display_name":"Lin Zhang","orcid":"https://orcid.org/0000-0002-7404-5231"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Zhang","raw_affiliation_strings":["School of Information and Electrical Engineering, China University of Mining and Technology, Xuzhou, China","Sch. of Inf. & Electr. Eng., China Univ. of Min. & Technol., Xuzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information and Electrical Engineering, China University of Mining and Technology, Xuzhou, China","institution_ids":["https://openalex.org/I25757504"]},{"raw_affiliation_string":"Sch. of Inf. & Electr. Eng., China Univ. of Min. & Technol., Xuzhou, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061712236","display_name":"Shao\u2010Wu Zhang","orcid":"https://orcid.org/0000-0003-1305-7447"},"institutions":[{"id":"https://openalex.org/I17145004","display_name":"Northwestern Polytechnical University","ror":"https://ror.org/01y0j0j86","country_code":"CN","type":"education","lineage":["https://openalex.org/I17145004"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaowu Zhang","raw_affiliation_strings":["School of Automation, Northwestern Polytechnical University, Xian, China","Sch. of Autom., Northwestern Polytech. Univ., Xi'an, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Automation, Northwestern Polytechnical University, Xian, China","institution_ids":["https://openalex.org/I17145004"]},{"raw_affiliation_string":"Sch. of Autom., Northwestern Polytech. Univ., Xi'an, China","institution_ids":["https://openalex.org/I17145004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060628869","display_name":"Manjeet K. Rao","orcid":"https://orcid.org/0000-0001-7573-2677"},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]},{"id":"https://openalex.org/I4210121077","display_name":"Cancer Research Institute of the Slovak Academy of Sciences","ror":"https://ror.org/02v8wkr26","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210121077"]}],"countries":["SK","US"],"is_corresponding":false,"raw_author_name":"Manjeet K. Rao","raw_affiliation_strings":["Greehey Children's Cancer Research Institute","Dept. of Cellular Struct. Biol., Univ. of Texas Health Sci. Center at San Antonio, San Antonio, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute","institution_ids":["https://openalex.org/I4210121077"]},{"raw_affiliation_string":"Dept. of Cellular Struct. Biol., Univ. of Texas Health Sci. Center at San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100689057","display_name":"Yidong Chen","orcid":"https://orcid.org/0000-0001-6806-2185"},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]},{"id":"https://openalex.org/I4210121077","display_name":"Cancer Research Institute of the Slovak Academy of Sciences","ror":"https://ror.org/02v8wkr26","country_code":"SK","type":"facility","lineage":["https://openalex.org/I207624831","https://openalex.org/I4210121077"]}],"countries":["SK","US"],"is_corresponding":false,"raw_author_name":"Yidong Chen","raw_affiliation_strings":["Greehey Children's Cancer Research Institute","Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Greehey Children's Cancer Research Institute","institution_ids":["https://openalex.org/I4210121077"]},{"raw_affiliation_string":"Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068887242","display_name":"Yufei Huang","orcid":"https://orcid.org/0000-0001-6268-5357"},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]},{"id":"https://openalex.org/I45438204","display_name":"The University of Texas at San Antonio","ror":"https://ror.org/01kd65564","country_code":"US","type":"education","lineage":["https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yufei Huang","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX, USA","Dept. of ECE, Univ. of Texas at San Antonio, San Antonio, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, University of Texas Health Science Center, San Antonio, TX, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Dept. of ECE, Univ. of Texas at San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I45438204"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.9914,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.89626367,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13157","display_name":"Cancer-related gene regulation","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.8251122832298279},{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.7111647129058838},{"id":"https://openalex.org/keywords/chromatin","display_name":"Chromatin","score":0.6615074276924133},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6579059958457947},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.6360548734664917},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.618707537651062},{"id":"https://openalex.org/keywords/transcriptome","display_name":"Transcriptome","score":0.5007517337799072},{"id":"https://openalex.org/keywords/rna-methylation","display_name":"RNA methylation","score":0.46871843934059143},{"id":"https://openalex.org/keywords/histone","display_name":"Histone","score":0.42777392268180847},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.4197843074798584},{"id":"https://openalex.org/keywords/epigenomics","display_name":"Epigenomics","score":0.41829076409339905},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.4071952700614929},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.37232643365859985},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3626246154308319},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3508910536766052},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.3501946032047272},{"id":"https://openalex.org/keywords/methyltransferase","display_name":"Methyltransferase","score":0.10935705900192261}],"concepts":[{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.8251122832298279},{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.7111647129058838},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.6615074276924133},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6579059958457947},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6360548734664917},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.618707537651062},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5007517337799072},{"id":"https://openalex.org/C2909856833","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"RNA methylation","level":5,"score":0.46871843934059143},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.42777392268180847},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.4197843074798584},{"id":"https://openalex.org/C121912465","wikidata":"https://www.wikidata.org/wiki/Q3589153","display_name":"Epigenomics","level":5,"score":0.41829076409339905},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4071952700614929},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.37232643365859985},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3626246154308319},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3508910536766052},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.3501946032047272},{"id":"https://openalex.org/C91965660","wikidata":"https://www.wikidata.org/wiki/Q415875","display_name":"Methyltransferase","level":4,"score":0.10935705900192261}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2013.6732477","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2013.6732477","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1963590871","https://openalex.org/W1964963969","https://openalex.org/W1974225991","https://openalex.org/W1981509058","https://openalex.org/W1982749428","https://openalex.org/W2011400542","https://openalex.org/W2015416439","https://openalex.org/W2024117723","https://openalex.org/W2026264107","https://openalex.org/W2041341260","https://openalex.org/W2044164623","https://openalex.org/W2045443950","https://openalex.org/W2046137036","https://openalex.org/W2052770715","https://openalex.org/W2054101905","https://openalex.org/W2055770801","https://openalex.org/W2065847836","https://openalex.org/W2070030982","https://openalex.org/W2074746593","https://openalex.org/W2078964320","https://openalex.org/W2085184586","https://openalex.org/W2093146349","https://openalex.org/W2097175728","https://openalex.org/W2102904139","https://openalex.org/W2110065044","https://openalex.org/W2124080033","https://openalex.org/W2134087142","https://openalex.org/W2152045787","https://openalex.org/W2155450834","https://openalex.org/W2155826575","https://openalex.org/W2166153887","https://openalex.org/W2166810745","https://openalex.org/W2171111703","https://openalex.org/W2171808845","https://openalex.org/W4231356616","https://openalex.org/W4237941089","https://openalex.org/W6819552753"],"related_works":["https://openalex.org/W4318473910","https://openalex.org/W4296034215","https://openalex.org/W4281776466","https://openalex.org/W1969931899","https://openalex.org/W2012031178","https://openalex.org/W2754983795","https://openalex.org/W2045361780","https://openalex.org/W1482953112","https://openalex.org/W1970572429","https://openalex.org/W2027174651"],"abstract_inverted_index":{"Despite":[0],"the":[1,24,46,63,68,71,114,130,141,148,155,178,181,214,270,279,283,298,334],"prevalent":[2],"studies":[3,330],"of":[4,26,57,74,77,104,116,143,157,184,314,326],"DNA/Chromatin":[5],"related":[6],"epigenetics,":[7],"such":[8,172],"as,":[9],"histone":[10],"modifications":[11],"and":[12,42,59,208,227,245,266,286,305,324],"DNA":[13],"methylation,":[14],"RNA":[15,79,105,133,145,158,310],"epigenetics":[16],"did":[17],"not":[18,90],"receive":[19],"deserved":[20],"attention":[21],"due":[22],"to":[23,44,65,128,189,251,297],"lack":[25],"high":[27],"throughput":[28],"approach":[29,38],"for":[30,67,102,168,242,261],"profiling":[31],"epitranscriptome.":[32],"Recently,":[33],"a":[34,55,98,120],"new":[35,85],"affinity-based":[36],"sequencing":[37],"MeRIPseq":[39,61,109,190,262,302,327],"was":[40,295],"developed":[41,97,167],"applied":[43,188,296],"survey":[45],"global":[47],"mRNA":[48],"N6-methyladenosine":[49],"(m6A)":[50],"in":[51,132,180,231,328,333],"mammalian":[52],"cells.":[53],"As":[54],"marriage":[56],"ChIPseq":[58],"RNAseq,":[60],"has":[62],"potential":[64],"study,":[66],"first":[69],"time,":[70],"transcriptome-wide":[72],"distribution":[73],"different":[75],"types":[76],"post-transcriptional":[78],"modifications.":[80],"Yet,":[81],"this":[82],"technology":[83],"introduced":[84],"computational":[86,122],"challenges":[87,323],"that":[88,124],"have":[89,95],"been":[91],"adequately":[92],"addressed.":[93],"We":[94],"previously":[96],"MATLAB-based":[99],"package":[100],"\u2018exomePeak\u2019":[101,207],"detection":[103],"methylation":[106],"sites":[107],"from":[108],"data.":[110],"Here,":[111],"we":[112],"extend":[113],"features":[115],"exomePeak":[117,254],"by":[118,195],"including":[119],"novel":[121,137],"framework":[123],"enables":[125],"differential":[126,138,170,198,267],"analysis":[127,139,171],"unveil":[129],"dynamics":[131],"epigenetic":[134,159],"regulations.":[135,160],"The":[136,200,293,322],"monitors":[140,177],"percentage":[142],"modified":[144],"molecules":[146],"among":[147],"total":[149],"transcribed":[150],"RNAs,":[151],"which":[152,234,315],"directly":[153,213],"reflects":[154],"impact":[156],"In":[161],"contrast,":[162],"current":[163],"available":[164],"software":[165],"packages":[166],"sequencing-based":[169],"as":[173,204,218,276,278],"DESeq":[174],"or":[175],"edgeR":[176],"changes":[179],"absolute":[182],"amount":[183],"molecules,":[185],"and,":[186],"if":[187],"data,":[191],"might":[192],"be":[193],"dominated":[194],"transcriptional":[196],"gene":[197],"expression.":[199],"algorithm":[201,294],"is":[202,235,256],"implemented":[203],"an":[205],"R-package":[206,255],"freely":[209],"available.":[210],"It":[211],"takes":[212],"aligned":[215],"BAM":[216],"files":[217],"input,":[219],"statistically":[220],"supports":[221],"biological":[222],"replicates,":[223],"corrects":[224],"PCR":[225],"artifacts,":[226],"outputs":[228],"exome-based":[229],"results":[230],"BED":[232],"format,":[233],"compatible":[236],"with":[237,258],"all":[238],"major":[239],"genome":[240],"browsers":[241],"convenient":[243],"visualization":[244],"manipulation.":[246],"Examples":[247],"are":[248,290,316,331],"also":[249],"provided":[250],"depict":[252],"how":[253],"integrated":[257],"exiting":[259],"tools":[260],"based":[263],"peak":[264],"calling":[265],"analysis.":[268],"Particularly,":[269],"rationales":[271],"behind":[272],"each":[273],"processing":[274],"step":[275],"well":[277],"specific":[280],"method":[281],"used,":[282],"best":[284],"practice,":[285],"possible":[287],"alternative":[288],"strategies":[289],"briefly":[291],"discussed.":[292],"human":[299],"HepG2":[300],"cell":[301],"data":[303],"sets":[304],"detects":[306],"more":[307],"than":[308],"16000":[309],"m6A":[311],"sites,":[312],"many":[313],"differentially":[317],"methylated":[318],"under":[319],"ultraviolet":[320],"radiation.":[321],"potentials":[325],"epitranscriptome":[329],"discussed":[332],"end.":[335]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":7},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}
