{"id":"https://openalex.org/W2058908705","doi":"https://doi.org/10.1109/bibm.2012.6392661","title":"Parallel simulation of apoptotic receptor-clustering on GPGPU many-core architectures","display_name":"Parallel simulation of apoptotic receptor-clustering on GPGPU many-core architectures","publication_year":2012,"publication_date":"2012-10-01","ids":{"openalex":"https://openalex.org/W2058908705","doi":"https://doi.org/10.1109/bibm.2012.6392661","mag":"2058908705"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2012.6392661","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2012.6392661","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075469773","display_name":"Claus Braun","orcid":null},"institutions":[{"id":"https://openalex.org/I100066346","display_name":"University of Stuttgart","ror":"https://ror.org/04vnq7t77","country_code":"DE","type":"education","lineage":["https://openalex.org/I100066346"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Claus Braun","raw_affiliation_strings":["Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Stuttgart, Germany","Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Pfaffenwaldring 47, D-70569, Stuttgart, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]},{"raw_affiliation_string":"Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Pfaffenwaldring 47, D-70569, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062237163","display_name":"Markus Daub","orcid":null},"institutions":[{"id":"https://openalex.org/I100066346","display_name":"University of Stuttgart","ror":"https://ror.org/04vnq7t77","country_code":"DE","type":"education","lineage":["https://openalex.org/I100066346"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Markus Daub","raw_affiliation_strings":["Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Stuttgart, Germany","Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Pfaffenwaldring 57, D-70569, Stuttgart, Germany#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]},{"raw_affiliation_string":"Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Pfaffenwaldring 57, D-70569, Stuttgart, Germany#TAB#","institution_ids":["https://openalex.org/I100066346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089120933","display_name":"Alexander Sch\u00f6ll","orcid":null},"institutions":[{"id":"https://openalex.org/I100066346","display_name":"University of Stuttgart","ror":"https://ror.org/04vnq7t77","country_code":"DE","type":"education","lineage":["https://openalex.org/I100066346"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Alexander Scholl","raw_affiliation_strings":["Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Stuttgart, Germany","Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Pfaffenwaldring 57, D-70569, Stuttgart, Germany#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]},{"raw_affiliation_string":"Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Pfaffenwaldring 57, D-70569, Stuttgart, Germany#TAB#","institution_ids":["https://openalex.org/I100066346"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053506285","display_name":"Guido Schneider","orcid":"https://orcid.org/0000-0002-9689-6299"},"institutions":[{"id":"https://openalex.org/I100066346","display_name":"University of Stuttgart","ror":"https://ror.org/04vnq7t77","country_code":"DE","type":"education","lineage":["https://openalex.org/I100066346"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Guido Schneider","raw_affiliation_strings":["Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Stuttgart, Germany","Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Pfaffenwaldring 57, D-70569, Stuttgart, Germany#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]},{"raw_affiliation_string":"Institute of Analysis, Dynamics, and Modeling, University of Stuttgart, Pfaffenwaldring 57, D-70569, Stuttgart, Germany#TAB#","institution_ids":["https://openalex.org/I100066346"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008775226","display_name":"Hans-Joachim Wunderlich","orcid":"https://orcid.org/0000-0003-4536-8290"},"institutions":[{"id":"https://openalex.org/I100066346","display_name":"University of Stuttgart","ror":"https://ror.org/04vnq7t77","country_code":"DE","type":"education","lineage":["https://openalex.org/I100066346"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hans-Joachim Wunderlich","raw_affiliation_strings":["Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Stuttgart, Germany","Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Pfaffenwaldring 47, D-70569, Stuttgart, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]},{"raw_affiliation_string":"Institute of Computer Architecture and Computer Engineering, University of Stuttgart, Pfaffenwaldring 47, D-70569, Stuttgart, Germany","institution_ids":["https://openalex.org/I100066346"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I100066346"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9896000027656555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9896000027656555,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11829","display_name":"Mathematical Biology Tumor Growth","score":0.9864000082015991,"subfield":{"id":"https://openalex.org/subfields/2611","display_name":"Modeling and Simulation"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.984000027179718,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.7513147592544556},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.697571873664856},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.5861416459083557},{"id":"https://openalex.org/keywords/speedup","display_name":"Speedup","score":0.5306313037872314},{"id":"https://openalex.org/keywords/general-purpose-computing-on-graphics-processing-units","display_name":"General-purpose computing on graphics processing units","score":0.5178582668304443},{"id":"https://openalex.org/keywords/modeling-and-simulation","display_name":"Modeling and simulation","score":0.44650816917419434},{"id":"https://openalex.org/keywords/supercomputer","display_name":"Supercomputer","score":0.424085408449173},{"id":"https://openalex.org/keywords/core","display_name":"Core (optical fiber)","score":0.4222205579280853},{"id":"https://openalex.org/keywords/parallel-computing","display_name":"Parallel computing","score":0.4052751958370209},{"id":"https://openalex.org/keywords/simulation","display_name":"Simulation","score":0.2077322006225586},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.18387240171432495},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.07819652557373047},{"id":"https://openalex.org/keywords/graphics","display_name":"Graphics","score":0.07380005717277527}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.7513147592544556},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.697571873664856},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.5861416459083557},{"id":"https://openalex.org/C68339613","wikidata":"https://www.wikidata.org/wiki/Q1549489","display_name":"Speedup","level":2,"score":0.5306313037872314},{"id":"https://openalex.org/C50630238","wikidata":"https://www.wikidata.org/wiki/Q971505","display_name":"General-purpose computing on graphics processing units","level":3,"score":0.5178582668304443},{"id":"https://openalex.org/C167343916","wikidata":"https://www.wikidata.org/wiki/Q6888384","display_name":"Modeling and simulation","level":2,"score":0.44650816917419434},{"id":"https://openalex.org/C83283714","wikidata":"https://www.wikidata.org/wiki/Q121117","display_name":"Supercomputer","level":2,"score":0.424085408449173},{"id":"https://openalex.org/C2164484","wikidata":"https://www.wikidata.org/wiki/Q5170150","display_name":"Core (optical fiber)","level":2,"score":0.4222205579280853},{"id":"https://openalex.org/C173608175","wikidata":"https://www.wikidata.org/wiki/Q232661","display_name":"Parallel computing","level":1,"score":0.4052751958370209},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.2077322006225586},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.18387240171432495},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.07819652557373047},{"id":"https://openalex.org/C21442007","wikidata":"https://www.wikidata.org/wiki/Q1027879","display_name":"Graphics","level":2,"score":0.07380005717277527},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2012.6392661","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2012.6392661","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1642251103","https://openalex.org/W1996812667","https://openalex.org/W1998386780","https://openalex.org/W2030520011","https://openalex.org/W2051749664","https://openalex.org/W2066074704","https://openalex.org/W2068306188","https://openalex.org/W2070968944","https://openalex.org/W2088516779","https://openalex.org/W2098126561","https://openalex.org/W2106302614","https://openalex.org/W2124677924","https://openalex.org/W2140655851","https://openalex.org/W3104652402","https://openalex.org/W4231021340","https://openalex.org/W4234011924"],"related_works":["https://openalex.org/W2058965144","https://openalex.org/W2164382479","https://openalex.org/W2146343568","https://openalex.org/W98480971","https://openalex.org/W2150291671","https://openalex.org/W2013643406","https://openalex.org/W2027972911","https://openalex.org/W2157978810","https://openalex.org/W2597809628","https://openalex.org/W1980160788"],"abstract_inverted_index":{"Apoptosis,":[0],"the":[1,11,40,70,82,102,107,112,136,157,161],"programmed":[2],"cell":[3,41],"death,":[4],"is":[5,24,49],"a":[6,77,89,95,119],"physiological":[7],"process":[8,22,48],"that":[9],"handles":[10],"removal":[12],"of":[13,46,57,81,101,111,154,160],"unwanted":[14],"or":[15],"damaged":[16],"cells":[17],"in":[18,163],"living":[19],"organisms.":[20],"The":[21,43,141],"itself":[23],"initiated":[25],"by":[26,88],"signaling":[27,103],"through":[28],"tumor":[29],"necrosis":[30],"factor":[31],"(TNF)":[32],"receptors":[33],"and":[34,54,68,99],"ligands,":[35],"which":[36],"form":[37],"clusters":[38],"on":[39,135],"membrane.":[42],"exact":[44],"function":[45],"this":[47,74],"not":[50],"yet":[51],"fully":[52],"understood":[53],"currently":[55],"subject":[56],"basic":[58],"research.":[59,164],"Different":[60],"mathematical":[61],"models":[62],"have":[63],"been":[64,86,125],"developed":[65,142],"to":[66,93,106,118,150],"describe":[67],"simulate":[69],"apoptotic":[71,83],"receptor-clustering.":[72],"In":[73],"interdisciplinary":[75],"work,":[76],"previously":[78],"introduced":[79],"model":[80,162],"receptor-clustering":[84],"has":[85,124],"extended":[87],"new":[90],"receptor":[91],"type":[92],"allow":[94],"more":[96],"precise":[97],"description":[98],"simulation":[100,133,146],"process.":[104],"Due":[105],"high":[108],"computational":[109],"requirements":[110],"model,":[113],"an":[114],"efficient":[115],"algorithmic":[116],"mapping":[117,143],"modern":[120],"many-core":[121],"GPGPU":[122],"architecture":[123],"developed.":[126],"Such":[127],"architectures":[128],"enable":[129],"high-performance":[130],"computing":[131],"(HPC)":[132],"tasks":[134],"desktop":[137],"at":[138],"low":[139],"costs.":[140],"reduces":[144],"average":[145],"times":[147],"from":[148],"months":[149],"days":[151],"(peak":[152],"speedup":[153],"256x),":[155],"allowing":[156],"productive":[158],"use":[159]},"counts_by_year":[{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}