{"id":"https://openalex.org/W2034669994","doi":"https://doi.org/10.1109/bibm.2012.6392627","title":"Inferring Fuzzy Cognitive Map models for Gene Regulatory Networks from gene expression data","display_name":"Inferring Fuzzy Cognitive Map models for Gene Regulatory Networks from gene expression data","publication_year":2012,"publication_date":"2012-10-01","ids":{"openalex":"https://openalex.org/W2034669994","doi":"https://doi.org/10.1109/bibm.2012.6392627","mag":"2034669994"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2012.6392627","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2012.6392627","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100359095","display_name":"Ye Chen","orcid":"https://orcid.org/0000-0002-1080-7671"},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ye Chen","raw_affiliation_strings":["School of Electronics and Computing Systems, University of Cincinnati, Cincinnati, OH, USA","School of Electronics and Computing Systems, University of Cincinnati, Cincinnati, OH, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electronics and Computing Systems, University of Cincinnati, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"School of Electronics and Computing Systems, University of Cincinnati, Cincinnati, OH, United States","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062762550","display_name":"Lawrence J. Mazlack","orcid":null},"institutions":[{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence J. Mazlack","raw_affiliation_strings":["Applied Computational Intelligence Laboratory, University of Cincinnati, Cincinnati, OH, USA","Applied Computational Intelligence Laboratory, University of Cincinnati, Cincinnati, OH, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Applied Computational Intelligence Laboratory, University of Cincinnati, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I63135867"]},{"raw_affiliation_string":"Applied Computational Intelligence Laboratory, University of Cincinnati, Cincinnati, OH, United States","institution_ids":["https://openalex.org/I63135867"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013217302","display_name":"Long Lu","orcid":"https://orcid.org/0000-0003-1550-479X"},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Long J. Lu","raw_affiliation_strings":["Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Research Center, Cincinnati, OH, USA","Division of Biomedicai Informatics, Cincinnati Children's Hospital, Medical Center Cincinnati, OH, United States#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Research Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"Division of Biomedicai Informatics, Cincinnati Children's Hospital, Medical Center Cincinnati, OH, United States#TAB#","institution_ids":["https://openalex.org/I1285204247"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12805","display_name":"Cognitive Science and Mapping","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12805","display_name":"Cognitive Science and Mapping","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fuzzy-cognitive-map","display_name":"Fuzzy cognitive map","score":0.7624150514602661},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6432734727859497},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.5815980434417725},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.5374224185943604},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5245330929756165},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4806627035140991},{"id":"https://openalex.org/keywords/fuzzy-logic","display_name":"Fuzzy logic","score":0.46643757820129395},{"id":"https://openalex.org/keywords/bayesian-network","display_name":"Bayesian network","score":0.4237360656261444},{"id":"https://openalex.org/keywords/ant-colony-optimization-algorithms","display_name":"Ant colony optimization algorithms","score":0.4119192063808441},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.39171743392944336},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3271569311618805},{"id":"https://openalex.org/keywords/adaptive-neuro-fuzzy-inference-system","display_name":"Adaptive neuro fuzzy inference system","score":0.2599182724952698},{"id":"https://openalex.org/keywords/fuzzy-control-system","display_name":"Fuzzy control system","score":0.25891149044036865},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.24464309215545654},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.14070239663124084},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12547031044960022}],"concepts":[{"id":"https://openalex.org/C5041914","wikidata":"https://www.wikidata.org/wiki/Q5511107","display_name":"Fuzzy cognitive map","level":5,"score":0.7624150514602661},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6432734727859497},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.5815980434417725},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.5374224185943604},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5245330929756165},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4806627035140991},{"id":"https://openalex.org/C58166","wikidata":"https://www.wikidata.org/wiki/Q224821","display_name":"Fuzzy logic","level":2,"score":0.46643757820129395},{"id":"https://openalex.org/C33724603","wikidata":"https://www.wikidata.org/wiki/Q812540","display_name":"Bayesian network","level":2,"score":0.4237360656261444},{"id":"https://openalex.org/C40128228","wikidata":"https://www.wikidata.org/wiki/Q460851","display_name":"Ant colony optimization algorithms","level":2,"score":0.4119192063808441},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.39171743392944336},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3271569311618805},{"id":"https://openalex.org/C186108316","wikidata":"https://www.wikidata.org/wiki/Q352530","display_name":"Adaptive neuro fuzzy inference system","level":4,"score":0.2599182724952698},{"id":"https://openalex.org/C195975749","wikidata":"https://www.wikidata.org/wiki/Q1475705","display_name":"Fuzzy control system","level":3,"score":0.25891149044036865},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24464309215545654},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.14070239663124084},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12547031044960022},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2012.6392627","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2012.6392627","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 IEEE International Conference on Bioinformatics and Biomedicine","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.47999998927116394,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W1893022572","https://openalex.org/W1975009952","https://openalex.org/W2017731388","https://openalex.org/W2038153693","https://openalex.org/W2062029454","https://openalex.org/W2081232506","https://openalex.org/W2086478519","https://openalex.org/W2095224843","https://openalex.org/W2108579152","https://openalex.org/W2111123076","https://openalex.org/W2131398297"],"related_works":["https://openalex.org/W2063798559","https://openalex.org/W2991207020","https://openalex.org/W2145925682","https://openalex.org/W1661487699","https://openalex.org/W2560421304","https://openalex.org/W2950199998","https://openalex.org/W2951387065","https://openalex.org/W2349909726","https://openalex.org/W4385727351","https://openalex.org/W4306798985"],"abstract_inverted_index":{"Gene":[0],"Regulatory":[1],"Networks":[2],"(GRNs)":[3],"represent":[4,68],"the":[5,9,15,19,22,75,122,125,128,138,149,169],"causal":[6],"relations":[7],"among":[8],"genes":[10],"and":[11,18,42],"provide":[12],"insight":[13],"on":[14,110,160],"cellular":[16],"functions":[17],"mechanism":[20],"of":[21,35,48,74,124,137,151],"diseases.":[23],"GRNs":[24,49,69],"can":[25],"be":[26,59,141],"inferred":[27],"from":[28,162],"gene":[29],"expression":[30],"data":[31,161],"by":[32],"a":[33],"number":[34,150],"algorithms,":[36],"e.g.":[37],"Boolean":[38],"networks,":[39,41],"Bayesian":[40],"differential":[43],"equations.":[44],"While":[45],"reliable":[46],"inference":[47],"is":[50,65,93,103,108,118,132,158],"still":[51],"an":[52],"open":[53],"problem,":[54],"new":[55,90],"algorithms":[56,78],"need":[57],"to":[58,67,81,95,120,140,148],"developed.":[60],"Fuzzy":[61],"Cognitive":[62],"Maps":[63],"(FCMs)":[64],"used":[66],"in":[70,143],"this":[71],"paper.":[72],"Most":[73],"FCM":[76,129],"learning":[77,130],"are":[79],"able":[80,94],"learn":[82,96],"FCMs":[83,97],"with":[84,98],"less":[85],"than":[86,100],"40":[87],"nodes.":[88],"A":[89,115],"algorithm":[91,131],"that":[92],"more":[99,133],"100":[101],"nodes":[102,152],"proposed.":[104],"The":[105,155,165],"proposed":[106,119,156,170],"method":[107],"based":[109],"Ant":[111],"Colony":[112],"Optimization":[113],"(ACO).":[114],"decomposed":[116],"approach":[117,157,171],"reduce":[121],"dimension":[123,136],"problem;":[126],"therefore":[127],"scalable":[134],"(the":[135],"problem":[139],"solved":[142],"one":[144],"ACO":[145],"run":[146],"equals":[147],"or":[153],"genes).":[154],"tested":[159],"DREAM":[163],"project.":[164],"experiment":[166],"results":[167],"suggest":[168],"outperforms":[172],"several":[173],"other":[174],"algorithms.":[175]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":2}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}