{"id":"https://openalex.org/W2123423601","doi":"https://doi.org/10.1109/bibm.2010.5706629","title":"An automatic procedure to search highly repetitive sequences in genome as fluorescence in situ hybridization probes and its application on Brachypodium distachyon","display_name":"An automatic procedure to search highly repetitive sequences in genome as fluorescence in situ hybridization probes and its application on Brachypodium distachyon","publication_year":2010,"publication_date":"2010-12-01","ids":{"openalex":"https://openalex.org/W2123423601","doi":"https://doi.org/10.1109/bibm.2010.5706629","mag":"2123423601"},"language":"en","primary_location":{"id":"doi:10.1109/bibm.2010.5706629","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2010.5706629","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100640251","display_name":"Qiwei Li","orcid":"https://orcid.org/0000-0002-1020-3050"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qiwei Li","raw_affiliation_strings":["Department of Information Engineering, Chinese University of Hong Kong, New Territories, Hong Kong, China","Department of Information Engineering, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Information Engineering, Chinese University of Hong Kong, New Territories, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Information Engineering, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014272851","display_name":"Liang Tong","orcid":"https://orcid.org/0000-0002-7428-2114"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tong Liang","raw_affiliation_strings":["Department of Information Engineering, Chinese University of Hong Kong, New Territories, Hong Kong, China","Department of Information Engineering, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Information Engineering, Chinese University of Hong Kong, New Territories, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Information Engineering, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060018541","display_name":"Xiaodan Fan","orcid":"https://orcid.org/0000-0002-2744-9030"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaodan Fan","raw_affiliation_strings":["Department of Statistics, Chinese University of Hong Kong, New Territories, Hong Kong, China","Department of Statistics, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, Chinese University of Hong Kong, New Territories, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Statistics, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039469426","display_name":"Chunhui Xu","orcid":"https://orcid.org/0000-0001-9379-4599"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunhui Xu","raw_affiliation_strings":["Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory of Agrobiotechnology, Chinese University of Hong Kong, New Territories, Hong Kong, China","Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory of Agrobiotechnology, Chinese University of Hong Kong, New Territories, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055279606","display_name":"Weichang Yu","orcid":"https://orcid.org/0000-0003-0726-4239"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weichang Yu","raw_affiliation_strings":["Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory of Agrobiotechnology, Chinese University of Hong Kong, New Territories, Hong Kong, China","Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory of Agrobiotechnology, Chinese University of Hong Kong, New Territories, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Biology, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100386630","display_name":"Shuo Li","orcid":"https://orcid.org/0000-0002-5184-3230"},"institutions":[{"id":"https://openalex.org/I177725633","display_name":"Chinese University of Hong Kong","ror":"https://ror.org/00t33hh48","country_code":"CN","type":"education","lineage":["https://openalex.org/I177725633"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuo-Yen Robert Li","raw_affiliation_strings":["Department of Information Engineering, Chinese University of Hong Kong, New Territories, Hong Kong, China","Department of Information Engineering, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong"],"affiliations":[{"raw_affiliation_string":"Department of Information Engineering, Chinese University of Hong Kong, New Territories, Hong Kong, China","institution_ids":["https://openalex.org/I177725633"]},{"raw_affiliation_string":"Department of Information Engineering, Institute of Plant Molecular Biology and Agricultural Biotechnology, State (China) Key Laboratory for Agrobiotechnology The Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong","institution_ids":["https://openalex.org/I177725633"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5100640251"],"corresponding_institution_ids":["https://openalex.org/I177725633"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14227288,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":null,"first_page":"563","last_page":"568"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9948999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brachypodium-distachyon","display_name":"Brachypodium distachyon","score":0.9623612761497498},{"id":"https://openalex.org/keywords/brachypodium","display_name":"Brachypodium","score":0.8375725746154785},{"id":"https://openalex.org/keywords/fluorescence-in-situ-hybridization","display_name":"Fluorescence in situ hybridization","score":0.7124435901641846},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6408904790878296},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6243463158607483},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6013839244842529},{"id":"https://openalex.org/keywords/repeated-sequence","display_name":"Repeated sequence","score":0.584312379360199},{"id":"https://openalex.org/keywords/fish-actinopterygii","display_name":"Fish <Actinopterygii>","score":0.5399558544158936},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.42938265204429626},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.34410029649734497},{"id":"https://openalex.org/keywords/chromosome","display_name":"Chromosome","score":0.32528170943260193},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.09742239117622375}],"concepts":[{"id":"https://openalex.org/C2777911459","wikidata":"https://www.wikidata.org/wiki/Q2352209","display_name":"Brachypodium distachyon","level":4,"score":0.9623612761497498},{"id":"https://openalex.org/C2777749068","wikidata":"https://www.wikidata.org/wiki/Q157770","display_name":"Brachypodium","level":4,"score":0.8375725746154785},{"id":"https://openalex.org/C2777542201","wikidata":"https://www.wikidata.org/wiki/Q1336182","display_name":"Fluorescence in situ hybridization","level":4,"score":0.7124435901641846},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6408904790878296},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6243463158607483},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6013839244842529},{"id":"https://openalex.org/C169802333","wikidata":"https://www.wikidata.org/wiki/Q424473","display_name":"Repeated sequence","level":4,"score":0.584312379360199},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.5399558544158936},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.42938265204429626},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.34410029649734497},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.32528170943260193},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09742239117622375},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibm.2010.5706629","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibm.2010.5706629","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2010 IEEE International Conference on Bioinformatics and Biomedicine (BIBM)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W71822016","https://openalex.org/W1485215567","https://openalex.org/W1967134681","https://openalex.org/W1972171731","https://openalex.org/W1981828451","https://openalex.org/W2002027062","https://openalex.org/W2005699189","https://openalex.org/W2007096180","https://openalex.org/W2017915640","https://openalex.org/W2025072934","https://openalex.org/W2050345568","https://openalex.org/W2062518418","https://openalex.org/W2069644796","https://openalex.org/W2097126513","https://openalex.org/W2102049511","https://openalex.org/W2112814753","https://openalex.org/W2118515340","https://openalex.org/W2139240752","https://openalex.org/W2139833654","https://openalex.org/W2141720611","https://openalex.org/W2152882361","https://openalex.org/W2155508478","https://openalex.org/W4236925497","https://openalex.org/W4297045122","https://openalex.org/W6628942021"],"related_works":["https://openalex.org/W2061127538","https://openalex.org/W2765686843","https://openalex.org/W3044519297","https://openalex.org/W2086976271","https://openalex.org/W2101318828","https://openalex.org/W2045923795","https://openalex.org/W2111466313","https://openalex.org/W3195128094","https://openalex.org/W2021883728","https://openalex.org/W2123423601"],"abstract_inverted_index":{"Fluorescence":[0],"in":[1,18,100],"situ":[2],"hybridization":[3],"(FISH)":[4],"is":[5],"a":[6,85],"powerful":[7],"technique":[8],"that":[9,39],"localizes":[10],"specific":[11],"DNA":[12],"sequences":[13,31,48,60,83],"on":[14,108],"chromosomes":[15],"for":[16,64,79],"use":[17,98],"physical":[19],"and":[20,117],"genetic":[21,24],"maps":[22],"assembling,":[23],"counselling,":[25],"species":[26],"identification,":[27],"etc.":[28],"Highly":[29],"repetitive":[30,59,82],"are":[32,61],"considered":[33],"to":[34,97],"be":[35],"suitable":[36],"FISH":[37,50,89,101,122],"probes":[38],"can":[40],"avoid":[41],"many":[42],"potential":[43],"problems":[44],"of":[45,56,113,121],"using":[46],"unique":[47],"as":[49,68,88,91,93],"probes.":[51],"The":[52],"distinct":[53],"chromosomal":[54],"distributions":[55],"these":[57],"highly":[58,81],"also":[62],"ideal":[63],"labelling":[65],"purposes":[66],"such":[67],"karyotyping.":[69],"In":[70],"this":[71],"paper,":[72],"we":[73],"present":[74],"an":[75,94],"automatic":[76],"computational":[77],"procedure":[78],"searching":[80],"from":[84],"whole":[86],"genome":[87,112],"probes,":[90],"well":[92],"experimental":[95],"protocol":[96],"them":[99],"analysis.":[102],"We":[103],"successfully":[104],"applied":[105],"the":[106,109],"method":[107],"newly":[110],"released":[111],"Brachypodium":[114],"distachyon":[115],"(Brachypodium)":[116],"produced":[118],"satisfactory":[119],"results":[120],"experiment.":[123]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}