{"id":"https://openalex.org/W4406138440","doi":"https://doi.org/10.1109/bibe63649.2024.10820462","title":"The Effect of Multi-Channel tDCS on the Directed Connectivity Patterns of a Case with Focal Epilepsy Using a Multi-Feature Machine Learning Evaluation","display_name":"The Effect of Multi-Channel tDCS on the Directed Connectivity Patterns of a Case with Focal Epilepsy Using a Multi-Feature Machine Learning Evaluation","publication_year":2024,"publication_date":"2024-11-27","ids":{"openalex":"https://openalex.org/W4406138440","doi":"https://doi.org/10.1109/bibe63649.2024.10820462"},"language":"en","primary_location":{"id":"doi:10.1109/bibe63649.2024.10820462","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe63649.2024.10820462","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE 24th International Conference on Bioinformatics and Bioengineering (BIBE)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5115798822","display_name":"Alexandra Tsipourakis","orcid":null},"institutions":[{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Alexandra Tsipourakis","raw_affiliation_strings":["School of Electrical and Computer Engineering, Technical University of Crete,Chania,Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Technical University of Crete,Chania,Greece","institution_ids":["https://openalex.org/I55741626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103208989","display_name":"Marios Antonakakis","orcid":null},"institutions":[{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Marios Antonakakis","raw_affiliation_strings":["School of Electrical and Computer Engineering, Technical University of Crete,Chania,Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Technical University of Crete,Chania,Greece","institution_ids":["https://openalex.org/I55741626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075651234","display_name":"Fabian Kaiser","orcid":"https://orcid.org/0000-0002-0335-2859"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fabian Kaiser","raw_affiliation_strings":["Institute for Biomagnetism and Biosignalanalysis, University of Münster,Münster,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Biomagnetism and Biosignalanalysis, University of Münster,Münster,Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006178441","display_name":"Stefan Rampp","orcid":"https://orcid.org/0000-0002-4826-1520"},"institutions":[{"id":"https://openalex.org/I4210088053","display_name":"Universit\u00e4tsklinikum Erlangen","ror":"https://ror.org/0030f2a11","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210088053"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Rampp","raw_affiliation_strings":["University Hospital Erlangen,Dept. of Neurosurgery,Erlangen,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University Hospital Erlangen,Dept. of Neurosurgery,Erlangen,Germany","institution_ids":["https://openalex.org/I4210088053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065525659","display_name":"Stjepana Kovac","orcid":"https://orcid.org/0000-0002-2500-6893"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stjepana Kovac","raw_affiliation_strings":["Institute of Translational Neurology, University Hospital Münster,Epilepsy Center Münster-Osnabrück,Dept. of Neurology,Münster,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Translational Neurology, University Hospital Münster,Epilepsy Center Münster-Osnabrück,Dept. of Neurology,Münster,Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039052962","display_name":"Christoph Kellinghaus","orcid":"https://orcid.org/0000-0001-5491-2302"},"institutions":[{"id":"https://openalex.org/I4210135668","display_name":"Klinikum Osnabr\u00fcck","ror":"https://ror.org/04dc9g452","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210135668"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christoph Kellinghaus","raw_affiliation_strings":["Klinikum Osnabrück,Epilepsy Center Münster-Osnabrück,Dept. of Neurology,Osnabrück,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Klinikum Osnabrück,Epilepsy Center Münster-Osnabrück,Dept. of Neurology,Osnabrück,Germany","institution_ids":["https://openalex.org/I4210135668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026030959","display_name":"Gabriel M\u00f6ddel","orcid":"https://orcid.org/0000-0001-8196-0537"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gabriel M\u00f6ddel","raw_affiliation_strings":["Institute of Translational Neurology, University Hospital Münster,Epilepsy Center Münster-Osnabrück,Dept. of Neurology,Münster,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Translational Neurology, University Hospital Münster,Epilepsy Center Münster-Osnabrück,Dept. of Neurology,Münster,Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053572681","display_name":"Carsten H. Wolters","orcid":"https://orcid.org/0000-0001-6233-424X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carsten H. Wolters","raw_affiliation_strings":["Institute for Biomagnetism and Biosignalanalysis, University of Münster,Münster,Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Biomagnetism and Biosignalanalysis, University of Münster,Münster,Germany","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113661535","display_name":"Michalis Zervakis","orcid":null},"institutions":[{"id":"https://openalex.org/I55741626","display_name":"Technical University of Crete","ror":"https://ror.org/03f8bz564","country_code":"GR","type":"education","lineage":["https://openalex.org/I55741626"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Michalis Zervakis","raw_affiliation_strings":["School of Electrical and Computer Engineering, Technical University of Crete,Chania,Greece"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Technical University of Crete,Chania,Greece","institution_ids":["https://openalex.org/I55741626"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9728999733924866,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9728999733924866,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9678999781608582,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":0.9520000219345093,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.7504227161407471},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6799758672714233},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.6214085221290588},{"id":"https://openalex.org/keywords/channel","display_name":"Channel (broadcasting)","score":0.4439544677734375},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3678407073020935},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.2633405327796936},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.24220827221870422},{"id":"https://openalex.org/keywords/computer-network","display_name":"Computer network","score":0.14090684056282043}],"concepts":[{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.7504227161407471},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6799758672714233},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.6214085221290588},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.4439544677734375},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3678407073020935},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2633405327796936},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.24220827221870422},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.14090684056282043},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibe63649.2024.10820462","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe63649.2024.10820462","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2024 IEEE 24th International Conference on Bioinformatics and Bioengineering (BIBE)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2934909998","display_name":null,"funder_award_id":"6001551","funder_id":"https://openalex.org/F4320327897","funder_display_name":"Max-Planck-Institut f\u00fcr Mathematik in den Naturwissenschaften"},{"id":"https://openalex.org/G3048357198","display_name":null,"funder_award_id":"WO1425/7-1,RA2062/1-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3529185310","display_name":null,"funder_award_id":"ZMI1-2521FSB006","funder_id":"https://openalex.org/F4320321721","funder_display_name":"Bundesministerium f\u00fcr Gesundheit"},{"id":"https://openalex.org/G8812548867","display_name":null,"funder_award_id":"57663920","funder_id":"https://openalex.org/F4320320875","funder_display_name":"Deutscher Akademischer Austauschdienst"}],"funders":[{"id":"https://openalex.org/F4320320875","display_name":"Deutscher Akademischer Austauschdienst","ror":"https://ror.org/039djdh30"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321721","display_name":"Bundesministerium f\u00fcr Gesundheit","ror":"https://ror.org/05vp4ka74"},{"id":"https://openalex.org/F4320327897","display_name":"Max-Planck-Institut f\u00fcr Mathematik in den Naturwissenschaften","ror":"https://ror.org/00ez2he07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1860935432","https://openalex.org/W1980447390","https://openalex.org/W2019504700","https://openalex.org/W2101234009","https://openalex.org/W2103897917","https://openalex.org/W2137680378","https://openalex.org/W2142181855","https://openalex.org/W2979688556","https://openalex.org/W3092409589","https://openalex.org/W3105393471","https://openalex.org/W3165713689","https://openalex.org/W3216249515","https://openalex.org/W4200481178","https://openalex.org/W4200584542","https://openalex.org/W4311321775","https://openalex.org/W4381192822","https://openalex.org/W4392016305"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2395385109","https://openalex.org/W2773633178","https://openalex.org/W2080101436","https://openalex.org/W2802335767","https://openalex.org/W2356350882","https://openalex.org/W4388090985","https://openalex.org/W2390279801"],"abstract_inverted_index":{"The":[0,98,160],"present":[1],"study":[2,182],"explores":[3],"the":[4,58,74,86,90,109,130,137,151,177,184],"effect":[5],"of":[6,153,179,186],"multichannel":[7],"transcranial":[8],"Direct":[9],"Current":[10],"Stimulation":[11],"(mc-tDCS)":[12],"on":[13,57],"directed":[14],"EEG":[15,43,59,76,111],"connectivity":[16,71,87,99,107,138,168,189],"patterns":[17],"in":[18,73,105,129,150,169,201,204],"a":[19,39,102,147],"patient":[20],"with":[21,42,114,124,173,191,211],"refractory":[22,170],"focal":[23,171],"epilepsy.":[24],"A":[25],"double-blind,":[26],"sham-controlled":[27],"N":[28],"-of-":[29],"1":[30],"trial":[31],"was":[32,36,66],"conducted,":[33],"where":[34],"mc-tDCS":[35,164],"applied":[37],"over":[38],"two-week":[40],"period,":[41],"recordings":[44],"acquired":[45],"before":[46],"and":[47,50,89,197],"after":[48],"stimulation":[49],"sham":[51,131],"procedures":[52],"accordingly.":[53],"After":[54],"artifact":[55],"reduction":[56,104],"recordings,":[60],"Generalized":[61],"Partial":[62],"Directed":[63],"Coherence":[64],"(gPDC)":[65],"utilized,":[67],"to":[68,84],"investigate":[69],"effective":[70],"alterations":[72],"patient's":[75],"recordings.":[77],"Machine":[78],"learning":[79,141,193],"models":[80],"were":[81],"also":[82],"employed":[83],"evaluate":[85],"findings":[88],"interictal":[91,118],"spike-related":[92],"class":[93],"(spike":[94],"/":[95],"non-spike)":[96],"separability.":[97],"analysis":[100,190],"demonstrated":[101],"significant":[103,126],"gPDC":[106],"around":[108],"key":[110],"channels":[112],"associated":[113,210],"epileptic":[115,154,212],"activity,":[116,155],"specifically":[117],"epileptiform":[119],"discharges":[120],"(IEDs),":[121],"following":[122],"mc-tDCS,":[123],"no":[125],"changes":[127],"observed":[128],"condition.":[132],"Following":[133],"feature":[134],"extraction":[135],"from":[136],"analysis,":[139],"machine":[140,192],"validation":[142],"supported":[143],"these":[144],"findings,":[145],"revealing":[146],"potential":[148,185],"decrease":[149],"severity":[152],"as":[156],"indicated":[157],"by":[158],"IEDs.":[159,180],"results":[161],"suggest":[162],"that":[163],"effectively":[165],"moderates":[166],"brain":[167,207],"epilepsy,":[172,202],"implications":[174],"for":[175,194],"reducing":[176],"frequency":[178],"This":[181],"highlights":[183],"integrating":[187],"advanced":[188],"evaluating":[195],"mctDCS":[196],"similar":[198],"neuromodulation":[199],"therapies":[200],"particularly":[203],"modulating":[205],"pathological":[206],"network":[208],"dynamics":[209],"discharges.":[213]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}