{"id":"https://openalex.org/W2033258894","doi":"https://doi.org/10.1109/bibe.2008.4696744","title":"Complementary grouping of amino acids based on base-pairing","display_name":"Complementary grouping of amino acids based on base-pairing","publication_year":2008,"publication_date":"2008-10-01","ids":{"openalex":"https://openalex.org/W2033258894","doi":"https://doi.org/10.1109/bibe.2008.4696744","mag":"2033258894"},"language":"en","primary_location":{"id":"doi:10.1109/bibe.2008.4696744","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2008.4696744","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 8th IEEE International Conference on BioInformatics and BioEngineering","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114859362","display_name":"Minseo Park","orcid":"https://orcid.org/0000-0003-1205-6178"},"institutions":[{"id":"https://openalex.org/I133738476","display_name":"University of Massachusetts Lowell","ror":"https://ror.org/03hamhx47","country_code":"US","type":"education","lineage":["https://openalex.org/I133738476"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Minseo Park","raw_affiliation_strings":["Department of Computer Science, University of Massachusetts, Lowell, MA, USA","Department of Computer Science, University of Massachusetts, Lowell, MA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Massachusetts, Lowell, MA, USA","institution_ids":["https://openalex.org/I133738476"]},{"raw_affiliation_string":"Department of Computer Science, University of Massachusetts, Lowell, MA#TAB#","institution_ids":["https://openalex.org/I133738476"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033372947","display_name":"B.G. Kim","orcid":null},"institutions":[{"id":"https://openalex.org/I133738476","display_name":"University of Massachusetts Lowell","ror":"https://ror.org/03hamhx47","country_code":"US","type":"education","lineage":["https://openalex.org/I133738476"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B.G. Kim","raw_affiliation_strings":["Department of Computer Science, University of Massachusetts, Lowell, MA, USA","Department of Computer Science, University of Massachusetts, Lowell, MA#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Massachusetts, Lowell, MA, USA","institution_ids":["https://openalex.org/I133738476"]},{"raw_affiliation_string":"Department of Computer Science, University of Massachusetts, Lowell, MA#TAB#","institution_ids":["https://openalex.org/I133738476"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I133738476"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.7447495460510254},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6616748571395874},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5905213952064514},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4772638976573944},{"id":"https://openalex.org/keywords/alphabet","display_name":"Alphabet","score":0.45884618163108826},{"id":"https://openalex.org/keywords/base-pair","display_name":"Base pair","score":0.455628365278244},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4457705616950989},{"id":"https://openalex.org/keywords/pairing","display_name":"Pairing","score":0.4419712424278259},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.42019760608673096},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3905128240585327}],"concepts":[{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.7447495460510254},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6616748571395874},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5905213952064514},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4772638976573944},{"id":"https://openalex.org/C112876837","wikidata":"https://www.wikidata.org/wiki/Q837518","display_name":"Alphabet","level":2,"score":0.45884618163108826},{"id":"https://openalex.org/C185581394","wikidata":"https://www.wikidata.org/wiki/Q145911","display_name":"Base pair","level":3,"score":0.455628365278244},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4457705616950989},{"id":"https://openalex.org/C14103023","wikidata":"https://www.wikidata.org/wiki/Q11681459","display_name":"Pairing","level":3,"score":0.4419712424278259},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.42019760608673096},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3905128240585327},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C54101563","wikidata":"https://www.wikidata.org/wiki/Q124131","display_name":"Superconductivity","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibe.2008.4696744","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2008.4696744","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 8th IEEE International Conference on BioInformatics and BioEngineering","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Quality Education","score":0.7200000286102295,"id":"https://metadata.un.org/sdg/4"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W208817500","https://openalex.org/W1506828374","https://openalex.org/W1530641120","https://openalex.org/W2001316303","https://openalex.org/W2009198549","https://openalex.org/W2014059004","https://openalex.org/W2014906569","https://openalex.org/W2020816856","https://openalex.org/W2062393514","https://openalex.org/W2080382112","https://openalex.org/W2088539410","https://openalex.org/W2097892623","https://openalex.org/W2110400205","https://openalex.org/W2135914634","https://openalex.org/W2150452800","https://openalex.org/W2157516796","https://openalex.org/W2163413135","https://openalex.org/W4243407156","https://openalex.org/W6655478935"],"related_works":["https://openalex.org/W3015473028","https://openalex.org/W3201176751","https://openalex.org/W1993094293","https://openalex.org/W2029180842","https://openalex.org/W2024971119","https://openalex.org/W2057898405","https://openalex.org/W2953807518","https://openalex.org/W2258335979","https://openalex.org/W2766795546","https://openalex.org/W2963079118"],"abstract_inverted_index":{"DNA":[0],"sequence":[1],"analysis":[2],"is":[3,25,36,92,104,117,158,188],"at":[4],"the":[5,11,37,127,159,171],"core":[6],"of":[7,13,32,39,57,99,112,132,193],"bioinformatics":[8],"approaches":[9],"in":[10,43,70,178,190],"study":[12],"genomes,":[14],"genes":[15],"and":[16,35,74,77,108,138,140,165],"proteins.":[17,47],"Recent":[18],"studies":[19],"revealed":[20],"that":[21,185],"codon":[22],"(triplet":[23],"nucleotides)":[24],"a":[26,89,96,120,175,179],"useful":[27],"means":[28],"to":[29,46,94,162],"detect":[30],"patterns":[31,84,192],"genome":[33,180,194],"sequences":[34],"basis":[38],"amino":[40,59,63,101,113,133,144],"acids,":[41],"which":[42,157],"turn":[44],"translate":[45],"Sixty":[48],"four":[49,130],"codons":[50],"are":[51,151],"commonly":[52],"grouped":[53],"into":[54,65],"an":[55,166],"alphabet":[56,98],"twenty":[58,62,100],"acids.":[60,102,114],"Grouping":[61],"acids":[64,134],"reduced":[66,97,149],"alphabets":[67,150],"may":[68],"aid":[69],"detecting":[71,191],"patterns,":[72,156],"modeling":[73],"designing":[75],"proteins,":[76],"finding":[78],"consensus":[79],"sequences.":[80,195],"It":[81,103],"can":[82],"make":[83],"simply.":[85],"In":[86],"this":[87,186],"paper,":[88],"novel":[90],"approach":[91],"used":[93],"generate":[95],"based":[105],"on":[106,153],"base-pairing":[107,116],"incorporates":[109],"physical":[110],"features":[111],"The":[115,124,147,182],"formulated":[118],"by":[119],"complementary":[121],"tree":[122,125],"algorithm.":[123],"preserves":[126],"relationship":[128],"among":[129],"groups":[131],"(nonpolar,":[135],"polar,":[136],"basic,":[137],"acidic),":[139],"yet":[141],"generates":[142],"fifteen":[143],"acid":[145],"groups.":[146],"resulting":[148],"tested":[152],"alternative":[154],"splicing":[155],"process":[160,168],"related":[161],"protein":[163],"functions":[164],"important":[167],"for":[169],"increasing":[170],"diversity":[172],"arising":[173],"from":[174],"single":[176],"gene,":[177],"sequence.":[181],"evaluation":[183],"shows":[184],"grouping":[187],"efficient":[189]},"counts_by_year":[],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}