{"id":"https://openalex.org/W1980985392","doi":"https://doi.org/10.1109/bibe.2008.4696743","title":"A computer simulation model of gene replacement in vector populations","display_name":"A computer simulation model of gene replacement in vector populations","publication_year":2008,"publication_date":"2008-10-01","ids":{"openalex":"https://openalex.org/W1980985392","doi":"https://doi.org/10.1109/bibe.2008.4696743","mag":"1980985392"},"language":"en","primary_location":{"id":"doi:10.1109/bibe.2008.4696743","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2008.4696743","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 8th IEEE International Conference on BioInformatics and BioEngineering","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103404443","display_name":"Mauricio Guevara","orcid":null},"institutions":[{"id":"https://openalex.org/I98461037","display_name":"Tecnol\u00f3gico de Monterrey","ror":"https://ror.org/03ayjn504","country_code":"MX","type":"education","lineage":["https://openalex.org/I98461037"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Mauricio Guevara","raw_affiliation_strings":["Computer Science Department, ITESM Atizapan de Zaragoza, Mexico","Comput. Sci. Dept., ITESM, Zaragoza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, ITESM Atizapan de Zaragoza, Mexico","institution_ids":["https://openalex.org/I98461037"]},{"raw_affiliation_string":"Comput. Sci. Dept., ITESM, Zaragoza","institution_ids":["https://openalex.org/I98461037"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086290136","display_name":"Edgar E. Vallejo","orcid":"https://orcid.org/0000-0003-2805-7132"},"institutions":[{"id":"https://openalex.org/I98461037","display_name":"Tecnol\u00f3gico de Monterrey","ror":"https://ror.org/03ayjn504","country_code":"MX","type":"education","lineage":["https://openalex.org/I98461037"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Edgar E. Vallejo","raw_affiliation_strings":["Computer Science Department, ITESM Atizapan de Zaragoza, Mexico","Comput. Sci. Dept., ITESM, Zaragoza"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, ITESM Atizapan de Zaragoza, Mexico","institution_ids":["https://openalex.org/I98461037"]},{"raw_affiliation_string":"Comput. Sci. Dept., ITESM, Zaragoza","institution_ids":["https://openalex.org/I98461037"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I98461037"],"apc_list":null,"apc_paid":null,"fwci":0.8359,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.74875737,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"22","issue":null,"first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12134","display_name":"Insect symbiosis and bacterial influences","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12134","display_name":"Insect symbiosis and bacterial influences","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10494","display_name":"Plant Virus Research Studies","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9908000230789185,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transposable-element","display_name":"Transposable element","score":0.6191524267196655},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6146885752677917},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5975301265716553},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5904881954193115},{"id":"https://openalex.org/keywords/mechanism","display_name":"Mechanism (biology)","score":0.4479760229587555},{"id":"https://openalex.org/keywords/vector","display_name":"Vector (molecular biology)","score":0.44359123706817627},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.34770169854164124},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33697253465652466},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.29948902130126953},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2865021228790283},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.1626700460910797}],"concepts":[{"id":"https://openalex.org/C4918238","wikidata":"https://www.wikidata.org/wiki/Q121438","display_name":"Transposable element","level":4,"score":0.6191524267196655},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6146885752677917},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5975301265716553},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5904881954193115},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.4479760229587555},{"id":"https://openalex.org/C92087593","wikidata":"https://www.wikidata.org/wiki/Q427389","display_name":"Vector (molecular biology)","level":4,"score":0.44359123706817627},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.34770169854164124},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33697253465652466},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29948902130126953},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2865021228790283},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.1626700460910797},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C40767141","wikidata":"https://www.wikidata.org/wiki/Q285697","display_name":"Recombinant DNA","level":3,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibe.2008.4696743","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2008.4696743","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2008 8th IEEE International Conference on BioInformatics and BioEngineering","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W22981762","https://openalex.org/W179007910","https://openalex.org/W1415442047","https://openalex.org/W1525951248","https://openalex.org/W1550808487","https://openalex.org/W1566107011","https://openalex.org/W1981374258","https://openalex.org/W1986634633","https://openalex.org/W2004868096","https://openalex.org/W2040409958","https://openalex.org/W2044251005","https://openalex.org/W2084081006","https://openalex.org/W2097550154","https://openalex.org/W2120579606","https://openalex.org/W2142285504","https://openalex.org/W2151041036","https://openalex.org/W2167436395","https://openalex.org/W2575478013","https://openalex.org/W4210345393","https://openalex.org/W4255982026"],"related_works":["https://openalex.org/W4237591666","https://openalex.org/W2103833188","https://openalex.org/W2164152191","https://openalex.org/W1534300978","https://openalex.org/W2387589589","https://openalex.org/W68905254","https://openalex.org/W2026307780","https://openalex.org/W1998760771","https://openalex.org/W4390126747","https://openalex.org/W2063677980"],"abstract_inverted_index":{"In":[0,17],"this":[1],"paper,":[2],"we":[3],"conduct":[4],"a":[5,20,77,83],"series":[6],"of":[7,14,22,55,79,91],"computer":[8],"simulations":[9],"on":[10,34,50,88],"the":[11,51,61,69],"genetic":[12,89],"modification":[13,90],"disease":[15,84],"vectors.":[16],"our":[18],"model,":[19],"population":[21],"mosquitoes":[23],"is":[24,38],"modeled":[25],"as":[26],"DNA":[27,41],"sequences.":[28],"A":[29],"gene":[30],"drive":[31],"mechanism":[32],"based":[33,87],"simulated":[35,59],"transposable":[36],"elements":[37],"inserted":[39],"into":[40],"sequences":[42],"to":[43,46,95],"confer":[44],"immunity":[45],"individuals.":[47],"Different":[48],"scenarios":[49],"spread":[52],"and":[53],"prevalence":[54],"modified":[56],"genes":[57],"are":[58],"using":[60],"evolutionary":[62],"game":[63],"theory.":[64],"Preliminary":[65],"results":[66],"suggest":[67],"that":[68,82],"proposed":[70],"model":[71],"could":[72],"be":[73,96],"useful":[74],"for":[75],"identifying":[76],"set":[78],"population-level":[80],"conditions":[81],"control":[85],"strategy":[86],"vectors":[92],"should":[93],"satisfy":[94],"effective.":[97]},"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}