{"id":"https://openalex.org/W1990070442","doi":"https://doi.org/10.1109/bibe.2007.4375730","title":"Complete Backtranslation of Oligopeptides for Metabolic Pathways Exploration of Complex Environments using Functional Microarrays","display_name":"Complete Backtranslation of Oligopeptides for Metabolic Pathways Exploration of Complex Environments using Functional Microarrays","publication_year":2007,"publication_date":"2007-10-01","ids":{"openalex":"https://openalex.org/W1990070442","doi":"https://doi.org/10.1109/bibe.2007.4375730","mag":"1990070442"},"language":"en","primary_location":{"id":"doi:10.1109/bibe.2007.4375730","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2007.4375730","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE 7th International Symposium on BioInformatics and BioEngineering","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088547933","display_name":"Mohieddine Missaoui","orcid":"https://orcid.org/0000-0003-2126-6898"},"institutions":[{"id":"https://openalex.org/I4210099416","display_name":"Laboratoire d'Informatique, de Mod\u00e9lisation et d'Optimisation des Syst\u00e8mes","ror":"https://ror.org/00t3fpp34","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I198244214","https://openalex.org/I198244214","https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993","https://openalex.org/I4210099416","https://openalex.org/I4210123221","https://openalex.org/I4210159245","https://openalex.org/I4387154249"]},{"id":"https://openalex.org/I4210104097","display_name":"Institut Sup\u00e9rieur d\u2019Informatique, de Mod\u00e9lisation et de leurs Applications","ror":"https://ror.org/01bv2n867","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210104097"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mohieddine Missaoui","raw_affiliation_strings":["Laboratoire d'informatique et de modelisation et, Optimization des systemes (LIMOS), Aubiere, France","LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'informatique et de modelisation et, Optimization des systemes (LIMOS), Aubiere, France","institution_ids":["https://openalex.org/I4210099416"]},{"raw_affiliation_string":"LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)","institution_ids":["https://openalex.org/I4210099416","https://openalex.org/I4210104097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113497930","display_name":"David R. Hill","orcid":null},"institutions":[{"id":"https://openalex.org/I4210099416","display_name":"Laboratoire d'Informatique, de Mod\u00e9lisation et d'Optimisation des Syst\u00e8mes","ror":"https://ror.org/00t3fpp34","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I198244214","https://openalex.org/I198244214","https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993","https://openalex.org/I4210099416","https://openalex.org/I4210123221","https://openalex.org/I4210159245","https://openalex.org/I4387154249"]},{"id":"https://openalex.org/I4210104097","display_name":"Institut Sup\u00e9rieur d\u2019Informatique, de Mod\u00e9lisation et de leurs Applications","ror":"https://ror.org/01bv2n867","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210104097"]},{"id":"https://openalex.org/I4210155419","display_name":"Center for Systems Biology","ror":"https://ror.org/05r3dyn47","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210155419","https://openalex.org/I48633490"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"David R.C. Hill","raw_affiliation_strings":["Laboratoire d'informatique et de modelisation et, Optimization des systemes (LIMOS), Aubiere, France","CCSB - Center for Cancer Systems Biology (450 Brookline Ave., Boston, MA 02215 - United States)","Department of Genetics [Boston] (77 Avenue Louis Pasteur, Boston, MA 02115 - United States)","LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire d'informatique et de modelisation et, Optimization des systemes (LIMOS), Aubiere, France","institution_ids":["https://openalex.org/I4210099416"]},{"raw_affiliation_string":"CCSB - Center for Cancer Systems Biology (450 Brookline Ave., Boston, MA 02215 - United States)","institution_ids":["https://openalex.org/I4210155419"]},{"raw_affiliation_string":"Department of Genetics [Boston] (77 Avenue Louis Pasteur, Boston, MA 02115 - United States)","institution_ids":[]},{"raw_affiliation_string":"LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)","institution_ids":["https://openalex.org/I4210099416","https://openalex.org/I4210104097"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026741136","display_name":"C\u00e9cile Militon","orcid":"https://orcid.org/0000-0002-5230-1732"},"institutions":[{"id":"https://openalex.org/I4210099416","display_name":"Laboratoire d'Informatique, de Mod\u00e9lisation et d'Optimisation des Syst\u00e8mes","ror":"https://ror.org/00t3fpp34","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I198244214","https://openalex.org/I198244214","https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993","https://openalex.org/I4210099416","https://openalex.org/I4210123221","https://openalex.org/I4210159245","https://openalex.org/I4387154249"]},{"id":"https://openalex.org/I4210103770","display_name":"Laboratoire de Biologie du D\u00e9veloppement","ror":"https://ror.org/024hnwe62","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210103770"]},{"id":"https://openalex.org/I4210104097","display_name":"Institut Sup\u00e9rieur d\u2019Informatique, de Mod\u00e9lisation et de leurs Applications","ror":"https://ror.org/01bv2n867","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210104097"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cecile Militon","raw_affiliation_strings":["Laboratoire de Biologie des Protistes, Aubiere, France","LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie des Protistes, Aubiere, France","institution_ids":["https://openalex.org/I4210103770"]},{"raw_affiliation_string":"LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)","institution_ids":["https://openalex.org/I4210099416","https://openalex.org/I4210104097"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002447097","display_name":"Pierre Peyret","orcid":"https://orcid.org/0000-0003-3114-0586"},"institutions":[{"id":"https://openalex.org/I4210099416","display_name":"Laboratoire d'Informatique, de Mod\u00e9lisation et d'Optimisation des Syst\u00e8mes","ror":"https://ror.org/00t3fpp34","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I198244214","https://openalex.org/I198244214","https://openalex.org/I203339264","https://openalex.org/I205703379","https://openalex.org/I3019848993","https://openalex.org/I4210099416","https://openalex.org/I4210123221","https://openalex.org/I4210159245","https://openalex.org/I4387154249"]},{"id":"https://openalex.org/I4210103770","display_name":"Laboratoire de Biologie du D\u00e9veloppement","ror":"https://ror.org/024hnwe62","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210103770"]},{"id":"https://openalex.org/I4210104097","display_name":"Institut Sup\u00e9rieur d\u2019Informatique, de Mod\u00e9lisation et de leurs Applications","ror":"https://ror.org/01bv2n867","country_code":"FR","type":"education","lineage":["https://openalex.org/I4210104097"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Peyret","raw_affiliation_strings":["Laboratoire de Biologie des Protistes, Aubiere, France","LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratoire de Biologie des Protistes, Aubiere, France","institution_ids":["https://openalex.org/I4210103770"]},{"raw_affiliation_string":"LIMOS - Laboratoire d'Informatique, de Mod\u00e9lisation et d'optimisation des Syst\u00e8mes (B\u00e2t ISIMA Campus des C\u00e9zeaux BP 10025 63173 AUBIERE cedex - France)","institution_ids":["https://openalex.org/I4210099416","https://openalex.org/I4210104097"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.11535625,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"28","issue":null,"first_page":"1275","last_page":"1279"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oligopeptide","display_name":"Oligopeptide","score":0.7282393574714661},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.6669102311134338},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5881738662719727},{"id":"https://openalex.org/keywords/degeneracy","display_name":"Degeneracy (biology)","score":0.5578382611274719},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5198841094970703},{"id":"https://openalex.org/keywords/dna-microarray","display_name":"DNA microarray","score":0.5173484683036804},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3587362468242645},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.2843219041824341},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.26953285932540894},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.16497811675071716},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.15982088446617126},{"id":"https://openalex.org/keywords/peptide","display_name":"Peptide","score":0.14850303530693054}],"concepts":[{"id":"https://openalex.org/C13935069","wikidata":"https://www.wikidata.org/wiki/Q2157266","display_name":"Oligopeptide","level":3,"score":0.7282393574714661},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6669102311134338},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5881738662719727},{"id":"https://openalex.org/C2777727622","wikidata":"https://www.wikidata.org/wiki/Q5251772","display_name":"Degeneracy (biology)","level":2,"score":0.5578382611274719},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5198841094970703},{"id":"https://openalex.org/C95371953","wikidata":"https://www.wikidata.org/wiki/Q591745","display_name":"DNA microarray","level":4,"score":0.5173484683036804},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3587362468242645},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.2843219041824341},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26953285932540894},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16497811675071716},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15982088446617126},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.14850303530693054},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/bibe.2007.4375730","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2007.4375730","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE 7th International Symposium on BioInformatics and BioEngineering","raw_type":"proceedings-article"},{"id":"pmh:oai:HAL:hal-00529941v1","is_oa":false,"landing_page_url":"https://hal.science/hal-00529941","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics and Bioengineering, 2007, pp.1275-1279. ⟨10.1109/BIBE.2007.4375730⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-00704699v1","is_oa":false,"landing_page_url":"https://hal.science/hal-00704699","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"7th IEEE International Conference on Bioinformatics and Bioengineering, Oct 2007, Boston (MA), France. pp.1275-1279","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.49000000953674316,"id":"https://metadata.un.org/sdg/15","display_name":"Life in Land"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W102715436","https://openalex.org/W1881907338","https://openalex.org/W1990636134","https://openalex.org/W2011634475","https://openalex.org/W2034137368","https://openalex.org/W2034313449","https://openalex.org/W2042782470","https://openalex.org/W2046183549","https://openalex.org/W2055043387","https://openalex.org/W2095724872","https://openalex.org/W2122082071","https://openalex.org/W2125060316","https://openalex.org/W2129775611","https://openalex.org/W2132005107","https://openalex.org/W2137667485","https://openalex.org/W2164723830","https://openalex.org/W4236236547","https://openalex.org/W4238603890"],"related_works":["https://openalex.org/W2372940580","https://openalex.org/W2072629609","https://openalex.org/W2005909632","https://openalex.org/W2492871722","https://openalex.org/W2515244650","https://openalex.org/W2556827910","https://openalex.org/W2101113459","https://openalex.org/W2060420196","https://openalex.org/W2002974473","https://openalex.org/W2369375436"],"abstract_inverted_index":{"When":[0],"studying":[1],"complex":[2],"environments":[3],"where":[4],"the":[5,16,39,50,79,127],"composing":[6],"microorganisms":[7],"are":[8,32],"unknown,":[9],"exploratory":[10],"tools":[11],"able":[12,113],"to":[13,20,36,76,84,114],"tackle":[14],"with":[15],"biological":[17,141],"diversity":[18],"have":[19,77],"be":[21,26],"proposed.":[22],"DNA":[23],"microarrays":[24],"can":[25],"a":[27,34,44,60,67,117],"good":[28],"answer":[29],"if":[30],"we":[31,92,104,133],"in":[33,49],"position":[35],"propose":[37,105],"all":[38,78],"probes":[40],"that":[41,59],"could":[42],"target":[43],"specific":[45],"enzyme.":[46],"In":[47,70,89],"addition,":[48],"context":[51],"of":[52,63,87,120,129],"new":[53,130],"metabolic":[54],"pathways":[55],"discovery,":[56],"it":[57,73],"appears":[58],"full":[61],"backtranslation":[62,119],"oligopeptides":[64],"is":[65,74,124],"also":[66],"promising":[68],"approach.":[69],"both":[71],"contexts":[72],"preferable":[75],"complete":[80,118],"nucleic":[81],"sequences":[82],"corresponding":[83],"an":[85,106],"enzyme":[86],"interest.":[88],"this":[90],"paper,":[91],"revisit":[93],"existing":[94],"bioinformatics":[95],"applications,":[96],"which":[97],"bring":[98],"partial":[99],"reverse":[100],"translation":[101],"solutions,":[102],"and":[103,132,139],"algorithm":[107,123],"based":[108],"on":[109,137],"input":[110],"oligopeptide":[111],"degeneracy":[112],"efficiently":[115],"compute":[116],"oligopeptides.":[121],"This":[122],"precious":[125],"for":[126],"discovery":[128],"organisms":[131],"show":[134],"its":[135],"performance":[136],"simulated":[138],"real":[140],"datasets.":[142]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-08-26T07:47:46.906454","created_date":"2025-10-10T00:00:00"}