{"id":"https://openalex.org/W2132185146","doi":"https://doi.org/10.1109/bibe.2007.4375587","title":"Homomorphisms of Multisource Trees into Networks with Applications to Metabolic Pathways","display_name":"Homomorphisms of Multisource Trees into Networks with Applications to Metabolic Pathways","publication_year":2007,"publication_date":"2007-10-01","ids":{"openalex":"https://openalex.org/W2132185146","doi":"https://doi.org/10.1109/bibe.2007.4375587","mag":"2132185146"},"language":"en","primary_location":{"id":"doi:10.1109/bibe.2007.4375587","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2007.4375587","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE 7th International Symposium on BioInformatics and BioEngineering","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068224540","display_name":"Qiong Cheng","orcid":null},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qiong Cheng","raw_affiliation_strings":["Department of Computer Science, Georgia State University, Atlanta, GA, USA","Georgia State University,Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Georgia State University,Atlanta","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007378854","display_name":"Robert W. Harrison","orcid":"https://orcid.org/0000-0003-2449-1214"},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Harrison","raw_affiliation_strings":["Department of Computer Science, Georgia State University, Atlanta, GA, USA","Georgia State University,Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Georgia State University,Atlanta","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072751459","display_name":"Alex Zelikovsky","orcid":"https://orcid.org/0000-0003-4424-4691"},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander Zelikovsky","raw_affiliation_strings":["Department of Computer Science, Georgia State University, Atlanta, GA, USA","Georgia State University,Atlanta"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Georgia State University, Atlanta, GA, USA","institution_ids":["https://openalex.org/I181565077"]},{"raw_affiliation_string":"Georgia State University,Atlanta","institution_ids":["https://openalex.org/I181565077"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8076,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.7192614,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"32","issue":null,"first_page":"350","last_page":"357"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pairwise-comparison","display_name":"Pairwise comparison","score":0.7415041923522949},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6948492527008057},{"id":"https://openalex.org/keywords/homomorphism","display_name":"Homomorphism","score":0.5794817209243774},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.5146466493606567},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.49604639410972595},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.4570789635181427},{"id":"https://openalex.org/keywords/biological-network","display_name":"Biological network","score":0.443185955286026},{"id":"https://openalex.org/keywords/dynamic-programming","display_name":"Dynamic programming","score":0.42565932869911194},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3358858823776245},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.32444190979003906},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.29570597410202026},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.21385714411735535},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15055504441261292},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.13865596055984497},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.12216520309448242},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.09709110856056213}],"concepts":[{"id":"https://openalex.org/C184898388","wikidata":"https://www.wikidata.org/wiki/Q1435712","display_name":"Pairwise comparison","level":2,"score":0.7415041923522949},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6948492527008057},{"id":"https://openalex.org/C4042151","wikidata":"https://www.wikidata.org/wiki/Q215111","display_name":"Homomorphism","level":2,"score":0.5794817209243774},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.5146466493606567},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.49604639410972595},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.4570789635181427},{"id":"https://openalex.org/C28225019","wikidata":"https://www.wikidata.org/wiki/Q4915005","display_name":"Biological network","level":2,"score":0.443185955286026},{"id":"https://openalex.org/C37404715","wikidata":"https://www.wikidata.org/wiki/Q380679","display_name":"Dynamic programming","level":2,"score":0.42565932869911194},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3358858823776245},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.32444190979003906},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.29570597410202026},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.21385714411735535},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15055504441261292},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.13865596055984497},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.12216520309448242},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.09709110856056213}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/bibe.2007.4375587","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2007.4375587","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2007 IEEE 7th International Symposium on BioInformatics and BioEngineering","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.87.2149","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.87.2149","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cs.gsu.edu/~cscqxcx/papers/BIBE07_Mst2DAG41.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1553495564","https://openalex.org/W1581844353","https://openalex.org/W1603241183","https://openalex.org/W1970737407","https://openalex.org/W2094490516","https://openalex.org/W2100438221","https://openalex.org/W2106202847","https://openalex.org/W2108078368","https://openalex.org/W2121773288","https://openalex.org/W2122037798","https://openalex.org/W2136316164","https://openalex.org/W2156966633","https://openalex.org/W2158784643","https://openalex.org/W2167222948","https://openalex.org/W4231551535","https://openalex.org/W6633180781","https://openalex.org/W6675077830"],"related_works":["https://openalex.org/W4308159138","https://openalex.org/W4327811209","https://openalex.org/W1979798674","https://openalex.org/W3169947911","https://openalex.org/W3037616202","https://openalex.org/W2487162673","https://openalex.org/W2963079901","https://openalex.org/W390508480","https://openalex.org/W2294450783","https://openalex.org/W2375240985"],"abstract_inverted_index":{"Network":[0],"mapping":[1,35,121],"is":[2],"a":[3,105,140],"convenient":[4],"tool":[5],"for":[6,16,34,125],"comparing":[7],"and":[8,21,26,89,134,138,160],"exploring":[9],"biological":[10],"networks;":[11],"it":[12],"can":[13],"be":[14],"used":[15],"predicting":[17],"unknown":[18],"pathways,":[19],"fast":[20],"meaningful":[22],"searching":[23],"of":[24,122,144,151],"databases,":[25],"potentially":[27],"establishing":[28],"evolutionary":[29],"relations.":[30],"Unfortunately,":[31],"existing":[32,166],"tools":[33],"paths":[36],"into":[37,43,74],"general":[38,84,115],"networks":[39,45],"(PathBlast)":[40],"or":[41,54],"trees":[42],"tree":[44,107],"allowing":[46,65],"gaps":[47],"(MetaPathwayHunter)":[48],"cannot":[49],"handle":[50,92],"large":[51,142],"query":[52,72],"pathways":[53,124,156],"complex":[55],"networks.":[56,80,116],"In":[57],"this":[58],"paper":[59],"we":[60],"consider":[61],"homomorphisms,":[62],"i.e.,":[63],"mappings":[64,153],"to":[66,91,108],"map":[67],"different":[68],"enzymes":[69],"from":[70,78,104],"the":[71,75,79,100],"pathway":[73,147,163,167],"same":[76],"enzyme":[77],"Homomorphisms":[81],"are":[82],"more":[83],"than":[85],"homeomorphism":[86],"(allowing":[87],"gaps)":[88],"easier":[90],"algorithmically.":[93],"Our":[94],"dynamic":[95],"programming":[96],"algorithm":[97],"efficiently":[98],"finds":[99],"minimum":[101],"cost":[102],"homomorphism":[103],"multisource":[106],"directed":[109],"acyclic":[110],"graphs":[111],"as":[112,114],"well":[113],"We":[117],"have":[118],"performed":[119],"pairwise":[120],"all":[123],"four":[126],"organisms":[127],"(E.":[128],"coli,":[129],"S.":[130],"cerevisiae,":[131],"B.":[132],"subtilis":[133],"T.":[135],"thermophilus":[136],"species)":[137],"found":[139],"reasonably":[141],"set":[143],"statistically":[145],"significant":[146],"similarities.":[148],"Further":[149],"analysis":[150],"our":[152],"identifies":[154],"conserved":[155],"across":[157],"examined":[158],"species":[159],"indicates":[161],"potential":[162],"holes":[164],"in":[165],"descriptions.":[168]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}