{"id":"https://openalex.org/W2113626392","doi":"https://doi.org/10.1109/bibe.2004.1317362","title":"Death domain resource: an integrated protein domain database","display_name":"Death domain resource: an integrated protein domain database","publication_year":2004,"publication_date":"2004-11-30","ids":{"openalex":"https://openalex.org/W2113626392","doi":"https://doi.org/10.1109/bibe.2004.1317362","mag":"2113626392"},"language":"en","primary_location":{"id":"doi:10.1109/bibe.2004.1317362","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2004.1317362","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. Fourth IEEE Symposium on Bioinformatics and Bioengineering","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014303462","display_name":"Yong Deng","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Y.-W. Deng","raw_affiliation_strings":["Institute of Bioinformatics, National Yang-Ming University, Taiwan","Institute of Bioinformatics, National Yang-Ming University, Taiwan#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics, National Yang-Ming University, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics, National Yang-Ming University, Taiwan#TAB#","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111904854","display_name":"C.-H. Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"C.-H. Wei","raw_affiliation_strings":["Institute of Bioinformatics, National Yang-Ming University, Taiwan","Institute of Bioinformatics, National Yang-Ming University, Taiwan#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics, National Yang-Ming University, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics, National Yang-Ming University, Taiwan#TAB#","institution_ids":["https://openalex.org/I148366613"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109961376","display_name":"Ueng\u2010Cheng Yang","orcid":null},"institutions":[{"id":"https://openalex.org/I148366613","display_name":"National Yang Ming Chiao Tung University","ror":"https://ror.org/00se2k293","country_code":"TW","type":"education","lineage":["https://openalex.org/I148366613"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"U.-C. Yang","raw_affiliation_strings":["Institute of Bioinformatics, National Yang-Ming University, Taiwan","Institute of Bioinformatics, National Yang-Ming University, Taiwan#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Bioinformatics, National Yang-Ming University, Taiwan","institution_ids":["https://openalex.org/I148366613"]},{"raw_affiliation_string":"Institute of Bioinformatics, National Yang-Ming University, Taiwan#TAB#","institution_ids":["https://openalex.org/I148366613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11244079,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"333","last_page":"333"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.8816999793052673,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.8816999793052673,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.8776999711990356,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.8468999862670898,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.6037529706954956},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5752240419387817},{"id":"https://openalex.org/keywords/proteome","display_name":"Proteome","score":0.5721091032028198},{"id":"https://openalex.org/keywords/uniprot","display_name":"UniProt","score":0.5263106822967529},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.5242388844490051},{"id":"https://openalex.org/keywords/protein-domain","display_name":"Protein domain","score":0.511177122592926},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"Alternative splicing","score":0.4632284641265869},{"id":"https://openalex.org/keywords/rna-splicing","display_name":"RNA splicing","score":0.4377075433731079},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.41668933629989624},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.32320672273635864},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3093832731246948},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.22400689125061035},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1114816665649414}],"concepts":[{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.6037529706954956},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5752240419387817},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.5721091032028198},{"id":"https://openalex.org/C202264299","wikidata":"https://www.wikidata.org/wiki/Q905695","display_name":"UniProt","level":3,"score":0.5263106822967529},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.5242388844490051},{"id":"https://openalex.org/C144292202","wikidata":"https://www.wikidata.org/wiki/Q898273","display_name":"Protein domain","level":3,"score":0.511177122592926},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.4632284641265869},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.4377075433731079},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.41668933629989624},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.32320672273635864},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3093832731246948},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22400689125061035},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1114816665649414},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bibe.2004.1317362","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bibe.2004.1317362","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings. Fourth IEEE Symposium on Bioinformatics and Bioengineering","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.47999998927116394,"display_name":"Partnerships for the goals","id":"https://metadata.un.org/sdg/17"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2288906059","https://openalex.org/W4376862128","https://openalex.org/W4296966554","https://openalex.org/W2321791250","https://openalex.org/W4213427798","https://openalex.org/W2030530458","https://openalex.org/W2564462691","https://openalex.org/W2023199111","https://openalex.org/W2065030615","https://openalex.org/W2546159719"],"abstract_inverted_index":{"Summary":[0],"form":[1],"only":[2,7,36],"given.":[3],"Traditional":[4],"domain":[5,26,34,44,69,104,162,241],"database":[6,85,249],"provides":[8],"the":[9,15,38,94,113,125,156,160,209,236,256,259,269],"sequence":[10,17],"related":[11],"information,":[12,48,163],"such":[13,28,49],"as":[14,29,50,105],"consensus":[16],"or":[18,31],"a":[19,74,97,164,192,212],"position-specific":[20],"scoring":[21],"matrix.":[22],"The":[23,46,79,244],"so-called":[24],"integrated":[25,67,84],"databases,":[27],"InterPro":[30],"CDD":[32],"(conserved":[33],"database),":[35],"integrates":[37],"information":[39,118,129,144,181,206,254],"from":[40],"different":[41],"types":[42],"of":[43,81,89,195,211,261],"databases.":[45],"functional":[47],"alternative":[51,157,183],"splicing,":[52,184],"tissue,":[53],"protein":[54,68,161,165,185,231],"interactions,":[55],"etc.,":[56],"are":[57],"usually":[58],"missing.":[59],"Therefore,":[60],"it":[61],"is":[62,91,146,250],"important":[63],"to":[64,92,108,111,130,135,229,251],"have":[65,101],"an":[66,83,106],"database,":[70],"which":[71],"will":[72,188],"create":[73,136],"user-centric":[75,122],"environment":[76],"for":[77,86,138,148,247],"biologists.":[78],"advantage":[80],"creating":[82],"domains,":[87],"instead":[88],"genes,":[90],"discover":[93],"relations":[95],"within":[96],"gene":[98],"family.":[99],"We":[100],"used":[102],"death":[103],"example":[107],"explain":[109],"how":[110],"integrate":[112,252],"genome,":[114],"transcriptome,":[115],"and":[116,133,159,204,263],"proteome":[117],"together.":[119],"In":[120,141],"this":[121,248],"bioinformatics":[123],"environment,":[124],"users":[126],"may":[127,168],"use":[128],"make":[131],"observations":[132],"even":[134],"hypothesis":[137],"biomedical":[139,150],"research.":[140,151],"other":[142,230],"words,":[143],"integration":[145],"essential":[147],"information-driven":[149],"For":[152],"example,":[153],"by":[154,201],"integrating":[155,179,202],"splicing":[158],"variant":[166,186],"that":[167,187],"show":[169],"inhibitory":[170],"effect":[171],"on":[172],"signal":[173],"transduction":[174],"can":[175,224,265],"be":[176,189,198,220,225,227,266],"observed.":[177],"By":[178],"tissue":[180,196,203],"with":[182,207],"expressed":[190],"in":[191,214,268],"given":[193],"type":[194],"might":[197],"revealed.":[199],"Besides,":[200],"histology":[205],"pathway,":[208],"difference":[210],"pathway":[213],"normal":[215],"versus":[216],"tumor":[217],"cells":[218],"would":[219],"clear.":[221],"This":[222],"system":[223],"readily":[226],"applied":[228],"domains.":[232],"Thus,":[233],"we":[234],"name":[235],"whole":[237],"program":[238],"package":[239],"\"integrated":[240],"resource":[242],"(IDR)\".":[243],"ultimate":[245],"goal":[246],"medical":[253],"into":[255],"system,":[257],"so":[258],"relation":[260],"genotype":[262],"phenotype":[264],"established":[267],"future.":[270]},"counts_by_year":[],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}