{"id":"https://openalex.org/W2972856209","doi":"https://doi.org/10.1109/bhi.2019.8834556","title":"Longitudinal Prediction Modeling of Alzheimer Disease using Recurrent Neural Networks","display_name":"Longitudinal Prediction Modeling of Alzheimer Disease using Recurrent Neural Networks","publication_year":2019,"publication_date":"2019-05-01","ids":{"openalex":"https://openalex.org/W2972856209","doi":"https://doi.org/10.1109/bhi.2019.8834556","mag":"2972856209"},"language":"en","primary_location":{"id":"doi:10.1109/bhi.2019.8834556","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bhi.2019.8834556","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031348516","display_name":"Solale Tabarestani","orcid":"https://orcid.org/0000-0002-3051-0605"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Solale Tabarestani","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091308182","display_name":"Maryamossadat Aghili","orcid":"https://orcid.org/0000-0002-9686-4617"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maryamossadat Aghili","raw_affiliation_strings":["School of Computing and Information Sciences, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"School of Computing and Information Sciences, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007040259","display_name":"Mehdi Shojaie","orcid":"https://orcid.org/0000-0003-4421-6578"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehdi Shojaie","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018997740","display_name":"Christian Freytes","orcid":null},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian Freytes","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071922657","display_name":"Mercedes Cabrerizo","orcid":"https://orcid.org/0000-0002-0302-7300"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mercedes Cabrerizo","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058435585","display_name":"Armando Barreto","orcid":"https://orcid.org/0000-0002-5572-284X"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Armando Barreto","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090787101","display_name":"Naphtali Rishe","orcid":"https://orcid.org/0000-0002-1611-4067"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Naphtali Rishe","raw_affiliation_strings":["School of Computing and Information Sciences, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"School of Computing and Information Sciences, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026208704","display_name":"Rosie E. Curiel","orcid":"https://orcid.org/0000-0001-6505-7030"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rosie E. Curiel","raw_affiliation_strings":["Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083829140","display_name":"David Loewenstein","orcid":"https://orcid.org/0000-0001-6788-2798"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Loewenstein","raw_affiliation_strings":["Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Center for Cognitive Neuroscience and Aging, University of Miami Miller School of Medicine, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085264873","display_name":"Ranjan Duara","orcid":"https://orcid.org/0000-0001-8060-6309"},"institutions":[{"id":"https://openalex.org/I4210095266","display_name":"Mount Sinai Medical Center","ror":"https://ror.org/00wgjpw02","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210095266"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ranjan Duara","raw_affiliation_strings":["Wien Center for Alzheimer's Disease & Memory Disorders, Mount Sinai Medical Center, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Wien Center for Alzheimer's Disease & Memory Disorders, Mount Sinai Medical Center, Miami, FL, USA","institution_ids":["https://openalex.org/I4210095266"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049795323","display_name":"Malek Adjouadi","orcid":"https://orcid.org/0000-0001-5380-3155"},"institutions":[{"id":"https://openalex.org/I19700959","display_name":"Florida International University","ror":"https://ror.org/02gz6gg07","country_code":"US","type":"education","lineage":["https://openalex.org/I19700959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Malek Adjouadi","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Florida International University, Miami, FL, USA","institution_ids":["https://openalex.org/I19700959"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5031348516"],"corresponding_institution_ids":["https://openalex.org/I19700959"],"apc_list":null,"apc_paid":null,"fwci":1.2602,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.85307841,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9930999875068665,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.7610709071159363},{"id":"https://openalex.org/keywords/regression","display_name":"Regression","score":0.6569185853004456},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.620489776134491},{"id":"https://openalex.org/keywords/recurrent-neural-network","display_name":"Recurrent neural network","score":0.605832040309906},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5987322330474854},{"id":"https://openalex.org/keywords/mean-squared-error","display_name":"Mean squared error","score":0.5710416436195374},{"id":"https://openalex.org/keywords/neuroimaging","display_name":"Neuroimaging","score":0.5402275323867798},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.45369982719421387},{"id":"https://openalex.org/keywords/regression-analysis","display_name":"Regression analysis","score":0.44525957107543945},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"Cognitive impairment","score":0.4434128403663635},{"id":"https://openalex.org/keywords/pearson-product-moment-correlation-coefficient","display_name":"Pearson product-moment correlation coefficient","score":0.44180282950401306},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.43987375497817993},{"id":"https://openalex.org/keywords/alzheimers-disease","display_name":"Alzheimer's disease","score":0.41900312900543213},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4170542359352112},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.37094056606292725},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.22948849201202393},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.20490968227386475},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1708892285823822},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.16753274202346802},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.11616107821464539},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.10462379455566406}],"concepts":[{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.7610709071159363},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.6569185853004456},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.620489776134491},{"id":"https://openalex.org/C147168706","wikidata":"https://www.wikidata.org/wiki/Q1457734","display_name":"Recurrent neural network","level":3,"score":0.605832040309906},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5987322330474854},{"id":"https://openalex.org/C139945424","wikidata":"https://www.wikidata.org/wiki/Q1940696","display_name":"Mean squared error","level":2,"score":0.5710416436195374},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.5402275323867798},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.45369982719421387},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.44525957107543945},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.4434128403663635},{"id":"https://openalex.org/C55078378","wikidata":"https://www.wikidata.org/wiki/Q1136628","display_name":"Pearson product-moment correlation coefficient","level":2,"score":0.44180282950401306},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.43987375497817993},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.41900312900543213},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4170542359352112},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.37094056606292725},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.22948849201202393},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.20490968227386475},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1708892285823822},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.16753274202346802},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.11616107821464539},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10462379455566406},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/bhi.2019.8834556","is_oa":false,"landing_page_url":"https://doi.org/10.1109/bhi.2019.8834556","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W2031967811","https://openalex.org/W2064675550","https://openalex.org/W2101282194","https://openalex.org/W2124840546","https://openalex.org/W2153171432","https://openalex.org/W2157331557","https://openalex.org/W2215943502","https://openalex.org/W2326289026","https://openalex.org/W2474271774","https://openalex.org/W2518582440","https://openalex.org/W2570375830","https://openalex.org/W2622540365","https://openalex.org/W2805994308","https://openalex.org/W2807758560","https://openalex.org/W2887579667","https://openalex.org/W2890524465","https://openalex.org/W2890613996","https://openalex.org/W2910208794"],"related_works":["https://openalex.org/W2345184372","https://openalex.org/W3013515612","https://openalex.org/W2136184105","https://openalex.org/W2187500075","https://openalex.org/W2041399278","https://openalex.org/W2160451891","https://openalex.org/W2336974148","https://openalex.org/W2056016498","https://openalex.org/W3195168932","https://openalex.org/W1627958236"],"abstract_inverted_index":{"This":[0,52],"paper":[1],"proposes":[2],"an":[3],"implementation":[4],"of":[5,38,61,79,109,119],"Recurrent":[6,70],"Neural":[7],"Networks":[8],"(RNNs)":[9],"for":[10,84,100],"(a)":[11],"predicting":[12],"future":[13],"Mini-Mental":[14],"State":[15],"Examination":[16],"(MMSE)":[17],"scores":[18],"in":[19],"a":[20,26],"longitudinal":[21],"study":[22],"and":[23,48,68,77,97,116,128],"(b)":[24],"deploying":[25],"multiclass":[27],"multimodal":[28,53],"neuroimaging":[29],"classification":[30,86,115],"process":[31],"that":[32],"involves":[33],"three":[34],"different":[35],"known":[36],"stages":[37],"Alzheimer's":[39,49],"progression,":[40],"cognitively":[41],"normal":[42],"(CN),":[43],"Mild":[44],"Cognitive":[45],"Impairment":[46],"(MCI)":[47],"Disease":[50],"(AD).":[51],"data":[54],"is":[55],"fed":[56],"into":[57],"two":[58],"well-studied":[59],"variations":[60],"the":[62,80,85,91,101,107,110],"RNNs;":[63],"Long":[64],"Short-Term":[65],"Memory":[66],"(LSTM)":[67],"Gated":[69],"Unit":[71],"(GRU).":[72],"The":[73,104],"accuracy,":[74],"F-score,":[75],"sensitivity,":[76],"specificity":[78],"models":[81],"are":[82],"reported":[83],"task":[87],"as":[88,90],"well":[89],"root":[92],"mean":[93],"square":[94],"error":[95],"(RMSE)":[96],"correlation":[98],"coefficient":[99],"regression":[102,117],"task.":[103],"results":[105],"demonstrate":[106],"superiority":[108],"proposed":[111],"model":[112],"over":[113],"state-of-the-art":[114],"techniques":[118],"Support":[120,124],"Vector":[121,125],"Machine":[122],"(SVM),":[123],"Regression":[126],"(SVR)":[127],"Ridge":[129],"Regression.":[130]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}