{"id":"https://openalex.org/W4283707895","doi":"https://doi.org/10.1109/atsip55956.2022.9805914","title":"Combination of Volumetric and Topologic Brain Characteristics Towards a Diagnosis of Alzheimer\u2019s Disease in his Earlier Stage","display_name":"Combination of Volumetric and Topologic Brain Characteristics Towards a Diagnosis of Alzheimer\u2019s Disease in his Earlier Stage","publication_year":2022,"publication_date":"2022-05-24","ids":{"openalex":"https://openalex.org/W4283707895","doi":"https://doi.org/10.1109/atsip55956.2022.9805914"},"language":"en","primary_location":{"id":"doi:10.1109/atsip55956.2022.9805914","is_oa":false,"landing_page_url":"https://doi.org/10.1109/atsip55956.2022.9805914","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 6th International Conference on Advanced Technologies for Signal and Image Processing (ATSIP)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051908424","display_name":"Besma Mabrouk","orcid":"https://orcid.org/0000-0002-2378-6320"},"institutions":[{"id":"https://openalex.org/I142899784","display_name":"University of Sfax","ror":"https://ror.org/04d4sd432","country_code":"TN","type":"education","lineage":["https://openalex.org/I142899784"]}],"countries":["TN"],"is_corresponding":true,"raw_author_name":"Besma Mabrouk","raw_affiliation_strings":["Sfax University,National Engineers School,Advanced Technologies for Medicine and Signals ATMS, Department of Electrical and Computer Engineering,Tunisia"],"affiliations":[{"raw_affiliation_string":"Sfax University,National Engineers School,Advanced Technologies for Medicine and Signals ATMS, Department of Electrical and Computer Engineering,Tunisia","institution_ids":["https://openalex.org/I142899784"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101809830","display_name":"N. Bouzidi","orcid":null},"institutions":[{"id":"https://openalex.org/I4210165772","display_name":"Hopital Universitaire Habib Bourguiba","ror":"https://ror.org/052g5ww90","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210165772"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Nouha Bouzidi","raw_affiliation_strings":["University Hospital Habib Bourguiba,Department of Neurology,Sfax,Tunisia"],"affiliations":[{"raw_affiliation_string":"University Hospital Habib Bourguiba,Department of Neurology,Sfax,Tunisia","institution_ids":["https://openalex.org/I4210165772"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018531632","display_name":"Chokri Mhiri","orcid":"https://orcid.org/0000-0001-7591-6994"},"institutions":[{"id":"https://openalex.org/I4210165772","display_name":"Hopital Universitaire Habib Bourguiba","ror":"https://ror.org/052g5ww90","country_code":"TN","type":"healthcare","lineage":["https://openalex.org/I4210165772"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Chokri Mhiri","raw_affiliation_strings":["University Hospital Habib Bourguiba,Department of Neurology,Sfax,Tunisia"],"affiliations":[{"raw_affiliation_string":"University Hospital Habib Bourguiba,Department of Neurology,Sfax,Tunisia","institution_ids":["https://openalex.org/I4210165772"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110204317","display_name":"Ahmed Ben Hamida","orcid":null},"institutions":[{"id":"https://openalex.org/I142899784","display_name":"University of Sfax","ror":"https://ror.org/04d4sd432","country_code":"TN","type":"education","lineage":["https://openalex.org/I142899784"]}],"countries":["TN"],"is_corresponding":false,"raw_author_name":"Ahmed Ben Hamida","raw_affiliation_strings":["Sfax University,National Engineers School,Advanced Technologies for Medicine and Signals ATMS, Department of Electrical and Computer Engineering,Tunisia"],"affiliations":[{"raw_affiliation_string":"Sfax University,National Engineers School,Advanced Technologies for Medicine and Signals ATMS, Department of Electrical and Computer Engineering,Tunisia","institution_ids":["https://openalex.org/I142899784"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5051908424"],"corresponding_institution_ids":["https://openalex.org/I142899784"],"apc_list":null,"apc_paid":null,"fwci":0.5792,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.62501752,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.9941999912261963,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dementia","display_name":"Dementia","score":0.5471712946891785},{"id":"https://openalex.org/keywords/voxel","display_name":"Voxel","score":0.5301742553710938},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.45897454023361206},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.45177996158599854},{"id":"https://openalex.org/keywords/prodromal-stage","display_name":"Prodromal Stage","score":0.41661331057548523},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.39540886878967285},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.3875194191932678},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3666081428527832},{"id":"https://openalex.org/keywords/cognitive-impairment","display_name":"Cognitive impairment","score":0.3587491810321808},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.35150930285453796},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.34741687774658203},{"id":"https://openalex.org/keywords/cognition","display_name":"Cognition","score":0.3399335443973541},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.33481794595718384},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.20399942994117737},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.1693534255027771}],"concepts":[{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5471712946891785},{"id":"https://openalex.org/C54170458","wikidata":"https://www.wikidata.org/wiki/Q663554","display_name":"Voxel","level":2,"score":0.5301742553710938},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.45897454023361206},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.45177996158599854},{"id":"https://openalex.org/C2910528735","wikidata":"https://www.wikidata.org/wiki/Q1140331","display_name":"Prodromal Stage","level":4,"score":0.41661331057548523},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.39540886878967285},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3875194191932678},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3666081428527832},{"id":"https://openalex.org/C2984915365","wikidata":"https://www.wikidata.org/wiki/Q5141203","display_name":"Cognitive impairment","level":3,"score":0.3587491810321808},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35150930285453796},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.34741687774658203},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.3399335443973541},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33481794595718384},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.20399942994117737},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.1693534255027771}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/atsip55956.2022.9805914","is_oa":false,"landing_page_url":"https://doi.org/10.1109/atsip55956.2022.9805914","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2022 6th International Conference on Advanced Technologies for Signal and Image Processing (ATSIP)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life in Land","score":0.6600000262260437,"id":"https://metadata.un.org/sdg/15"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W130842367","https://openalex.org/W2007739294","https://openalex.org/W2032032832","https://openalex.org/W2530506442","https://openalex.org/W2557267879","https://openalex.org/W2614698462","https://openalex.org/W2810138282","https://openalex.org/W2995495466","https://openalex.org/W3080607577","https://openalex.org/W3160789190","https://openalex.org/W3171255193"],"related_works":["https://openalex.org/W3027020613","https://openalex.org/W2016533837","https://openalex.org/W3167885074","https://openalex.org/W2892386716","https://openalex.org/W2409059799","https://openalex.org/W4306164210","https://openalex.org/W1998563493","https://openalex.org/W4313316311","https://openalex.org/W1981474931","https://openalex.org/W4360978644"],"abstract_inverted_index":{"The":[0],"longevity":[1],"of":[2,22,38,68,89,96,123,129,196,203,230],"life":[3],"and":[4,15,118,126,151,159,164,182,200],"the":[5,9,36,39,66,87,93,143,147,152,175,206,209,219],"rapid":[6],"advances":[7],"in":[8,41,52,92,135,139,218,232],"medical":[10],"field":[11],"have":[12,106,214],"accentuated":[13],"more":[14,16],"neurodegenerative":[17,63],"diseases.":[18,64],"More":[19],"than":[20],"60%":[21],"cases":[23],"are":[24,142],"affected":[25],"by":[26],"Alzheimer,":[27],"an":[28,194,201],"incurable":[29],"disease.":[30],"Which":[31],"imposes":[32],"special":[33],"attention":[34],"for":[35,198,205],"diagnosis":[37,95],"dementia":[40],"his":[42,233],"earlier":[43],"stage.":[44,235],"Voxel-based":[45],"morphometry":[46],"(VBM)":[47],"has":[48],"been":[49,107],"effectively":[50],"used,":[51],"association":[53],"with":[54],"Structural":[55],"Magnetic":[56],"Resonance":[57],"Imaging":[58],"(MRI),":[59],"to":[60,73,85],"predict":[61],"multiple":[62],"Recently,":[65],"emergence":[67],"Diffusion-Weighted":[69],"imaging":[70],"opened":[71],"access":[72],"brain":[74,104,130],"comprehension.":[75],"In":[76],"this":[77,82,99,140],"study,":[78],"we":[79],"focus":[80],"on":[81],"two-imaging":[83],"modality":[84],"emphasize":[86],"contribution":[88],"hemispheric":[90],"asymmetries":[91],"earlier-stage":[94],"Alzheimer.":[97],"For":[98,174],"aim,":[100],"209":[101],"T1":[102],"weighted":[103],"MRIs,":[105],"examined:":[108],"55":[109],"normal":[110],"control":[111],"(NC),":[112],"106":[113],"mild":[114],"cognitive":[115],"impairment":[116],"(MCI),":[117],"48":[119],"AD.":[120],"Volumetric":[121],"measurements":[122],"subcortical":[124],"regions":[125],"topologic":[127],"proprieties":[128],"mapping":[131],"were":[132,168,172,187],"combined.":[133],"All":[134],"all,":[136],"features":[137],"used":[138,212],"work":[141],"average":[144,195],"shortest":[145],"path,":[146],"Average":[148],"Clustering":[149],"coefficient,":[150],"small":[153],"world":[154],"graph":[155],"characteristics,":[156],"although,":[157],"Hippocampus":[158],"Amygdala":[160],"Volume.":[161],"When":[162],"left":[163],"right":[165],"characteristic":[166],"values":[167],"determined,":[169],"asymmetry":[170,226],"scores":[171],"calculated.":[173],"classification":[176],"task,":[177],"a":[178,228],"random":[179],"forest":[180],"classifier":[181],"support":[183],"vector":[184],"machine":[185],"(SVM)":[186],"performed,":[188],"then":[189],"compared.":[190],"They":[191],"provided":[192],"respectively":[193],"0.72/0.60":[197],"accuracy":[199],"equality":[202],"0.77":[204],"Area":[207],"under":[208],"curve.":[210],"Both":[211],"algorithms":[213],"proven":[215],"their":[216],"efficiency":[217],"MCI":[220],"group":[221],"prediction,":[222],"which":[223],"confirms":[224],"hemisphere":[225],"as":[227],"biomarker":[229],"disease":[231],"prodromal":[234]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}