{"id":"https://openalex.org/W2784231503","doi":"https://doi.org/10.1109/asicon.2017.8252523","title":"Design of a closed-loop, bi-directional brain-machine-interface integrated on-chip spike sorting","display_name":"Design of a closed-loop, bi-directional brain-machine-interface integrated on-chip spike sorting","publication_year":2017,"publication_date":"2017-10-01","ids":{"openalex":"https://openalex.org/W2784231503","doi":"https://doi.org/10.1109/asicon.2017.8252523","mag":"2784231503"},"language":"en","primary_location":{"id":"doi:10.1109/asicon.2017.8252523","is_oa":false,"landing_page_url":"https://doi.org/10.1109/asicon.2017.8252523","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 IEEE 12th International Conference on ASIC (ASICON)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045667648","display_name":"Ting Ou","orcid":null},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ting Ou","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058683230","display_name":"Deng Luo","orcid":"https://orcid.org/0000-0003-0475-8268"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Deng Luo","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100326587","display_name":"Yuwei Zhang","orcid":"https://orcid.org/0000-0003-0787-9735"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuwei Zhang","raw_affiliation_strings":["Department of Electronic Engineering, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electronic Engineering, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023972038","display_name":"Yiqiao Liao","orcid":null},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiqiao Liao","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069619592","display_name":"Chang Cheng","orcid":"https://orcid.org/0000-0002-9802-489X"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chang Cheng","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100656860","display_name":"Milin Zhang","orcid":"https://orcid.org/0000-0001-6915-0734"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Milin Zhang","raw_affiliation_strings":["Department of Electronic Engineering, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electronic Engineering, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100454920","display_name":"Chun Zhang","orcid":"https://orcid.org/0000-0001-6848-2868"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chun Zhang","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100356864","display_name":"Zhihua Wang","orcid":"https://orcid.org/0000-0001-6567-0759"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhihua Wang","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100642396","display_name":"Xiang Xie","orcid":"https://orcid.org/0000-0002-6895-3145"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiang Xie","raw_affiliation_strings":["Institute of Microelectronics, Tsinghua University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Microelectronics, Tsinghua University","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I99065089"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"504","last_page":"507"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7021849155426025},{"id":"https://openalex.org/keywords/spike-sorting","display_name":"Spike sorting","score":0.6500937938690186},{"id":"https://openalex.org/keywords/sorting","display_name":"Sorting","score":0.6143479347229004},{"id":"https://openalex.org/keywords/spike","display_name":"Spike (software development)","score":0.6012609004974365},{"id":"https://openalex.org/keywords/amplifier","display_name":"Amplifier","score":0.5493254661560059},{"id":"https://openalex.org/keywords/chip","display_name":"Chip","score":0.5409359335899353},{"id":"https://openalex.org/keywords/channel","display_name":"Channel (broadcasting)","score":0.4289151430130005},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.38862597942352295},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3334091305732727},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2103995978832245},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.19407111406326294},{"id":"https://openalex.org/keywords/telecommunications","display_name":"Telecommunications","score":0.16309446096420288}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7021849155426025},{"id":"https://openalex.org/C2777613131","wikidata":"https://www.wikidata.org/wiki/Q2003571","display_name":"Spike sorting","level":3,"score":0.6500937938690186},{"id":"https://openalex.org/C111696304","wikidata":"https://www.wikidata.org/wiki/Q2303697","display_name":"Sorting","level":2,"score":0.6143479347229004},{"id":"https://openalex.org/C2781390188","wikidata":"https://www.wikidata.org/wiki/Q25203449","display_name":"Spike (software development)","level":2,"score":0.6012609004974365},{"id":"https://openalex.org/C194257627","wikidata":"https://www.wikidata.org/wiki/Q211554","display_name":"Amplifier","level":3,"score":0.5493254661560059},{"id":"https://openalex.org/C165005293","wikidata":"https://www.wikidata.org/wiki/Q1074500","display_name":"Chip","level":2,"score":0.5409359335899353},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.4289151430130005},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.38862597942352295},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3334091305732727},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2103995978832245},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.19407111406326294},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.16309446096420288},{"id":"https://openalex.org/C2776257435","wikidata":"https://www.wikidata.org/wiki/Q1576430","display_name":"Bandwidth (computing)","level":2,"score":0.0},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/asicon.2017.8252523","is_oa":false,"landing_page_url":"https://doi.org/10.1109/asicon.2017.8252523","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2017 IEEE 12th International Conference on ASIC (ASICON)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5299999713897705,"display_name":"Affordable and clean energy","id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1482432820","https://openalex.org/W1973009825","https://openalex.org/W2034676826","https://openalex.org/W2050293473","https://openalex.org/W2060583550","https://openalex.org/W2068711549","https://openalex.org/W2086338123","https://openalex.org/W2118755334","https://openalex.org/W2136104104","https://openalex.org/W2169766445","https://openalex.org/W2169866873","https://openalex.org/W2296138925","https://openalex.org/W2506634464","https://openalex.org/W2546328145","https://openalex.org/W2562633068","https://openalex.org/W4206246468"],"related_works":["https://openalex.org/W3136143059","https://openalex.org/W3178771700","https://openalex.org/W1968361507","https://openalex.org/W2037099207","https://openalex.org/W3035015922","https://openalex.org/W2124872530","https://openalex.org/W2097405940","https://openalex.org/W2990250786","https://openalex.org/W2366422659","https://openalex.org/W4377004198"],"abstract_inverted_index":{"This":[0],"paper":[1],"proposed":[2,12],"a":[3,6,67,74,80,128,148,165,184],"design":[4,173],"of":[5,15,59,77,83,167,187],"closed-loop,":[7],"bi-directional":[8],"brain-machine-interface":[9],"(BMI).":[10],"The":[11,52,94,110,172],"chip":[13],"consists":[14],"16-channel":[16,53,60],"neural":[17,20,54],"acquisition,":[18],"8-channel":[19],"stimulation,":[21],"action":[22,122],"potential":[23,123],"detection,":[24],"feature":[25],"extraction":[26],"and":[27,103,112,155],"support":[28],"vector":[29],"machine":[30],"(SVM)":[31],"for":[32,89],"spike":[33,50,125,160],"sorting.":[34],"A":[35,140],"closed-loop":[36],"control":[37],"strategy":[38],"is":[39,57,87,117,145,162],"utilized":[40],"to":[41,47,119,134],"trigger":[42],"different":[43,48],"stimulation":[44],"pattern":[45],"according":[46],"detected":[49,121],"categories.":[51],"signal":[55],"acquisition":[56],"comprised":[58],"low":[61],"noise":[62],"amplifier":[63],"(LNA)":[64],"which":[65],"shares":[66],"single":[68,141],"Programmable":[69],"Gain":[70],"Amplifier":[71],"(PGA)":[72],"draws":[73],"total":[75],"current":[76,98],"218uA":[78],"under":[79],"power":[81],"supply":[82],"3.3V.":[84],"Arbitrary":[85],"combination":[86],"realized":[88,163],"the":[90,96,100,104,120,132,138,151,168],"stimulator":[91],"channel":[92],"control.":[93],"frequency,":[95],"output":[97],"amplitude,":[99],"pulse":[101],"width":[102],"burst":[105],"number":[106],"are":[107],"all":[108],"tunable.":[109],"first":[111],"second":[113],"derivative":[114],"extrema":[115],"method":[116],"applied":[118],"before":[124],"sorting,":[126],"realizing":[127],"great":[129],"reduction":[130],"on":[131],"data":[133],"be":[135],"processed":[136],"in":[137,177],"SVM.":[139],"two-class":[142,159,169],"sorting":[143,161,170],"module":[144],"implemented":[146],"as":[147],"results":[149],"from":[150],"tradeoff":[152],"between":[153],"area":[154,186],"latency.":[156],"More":[157],"than":[158],"by":[164],"repeating":[166],"procedure.":[171],"has":[174],"been":[175],"fabricated":[176],"TSMC":[178],"180nm":[179],"HV":[180],"COMS":[181],"process,":[182],"occupying":[183],"silicon":[185],"5mm":[188],"\u00d7":[189],"2mm.":[190]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}