{"id":"https://openalex.org/W4414054198","doi":"https://doi.org/10.1109/access.2025.3606940","title":"Precision-Controlled Microwave Hyperthermia Preclinical System for Small Animal Studies","display_name":"Precision-Controlled Microwave Hyperthermia Preclinical System for Small Animal Studies","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4414054198","doi":"https://doi.org/10.1109/access.2025.3606940"},"language":"en","primary_location":{"id":"doi:10.1109/access.2025.3606940","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2025.3606940","pdf_url":null,"source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1109/access.2025.3606940","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016028436","display_name":"Hemanth Kumar Dontiboina","orcid":null},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"facility","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Hemanth Kumar Dontiboina","raw_affiliation_strings":["Department of Engineering Design, Indian Institute of Technology Madras, Chennai, India"],"raw_orcid":"https://orcid.org/0000-0002-3621-2369","affiliations":[{"raw_affiliation_string":"Department of Engineering Design, Indian Institute of Technology Madras, Chennai, India","institution_ids":["https://openalex.org/I24676775"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051247522","display_name":"Kavitha Arunachalam","orcid":"https://orcid.org/0000-0002-9532-5259"},"institutions":[{"id":"https://openalex.org/I24676775","display_name":"Indian Institute of Technology Madras","ror":"https://ror.org/03v0r5n49","country_code":"IN","type":"facility","lineage":["https://openalex.org/I24676775"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kavitha Arunachalam","raw_affiliation_strings":["Department of Engineering Design, Indian Institute of Technology Madras, Chennai, India"],"raw_orcid":"https://orcid.org/0000-0002-9532-5259","affiliations":[{"raw_affiliation_string":"Department of Engineering Design, Indian Institute of Technology Madras, Chennai, India","institution_ids":["https://openalex.org/I24676775"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5016028436"],"corresponding_institution_ids":["https://openalex.org/I24676775"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.20953192,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":"159334","last_page":"159344"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.9225999712944031,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.9225999712944031,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/specific-absorption-rate","display_name":"Specific absorption rate","score":0.7304999828338623},{"id":"https://openalex.org/keywords/microwave","display_name":"Microwave","score":0.685699999332428},{"id":"https://openalex.org/keywords/hyperthermia","display_name":"Hyperthermia","score":0.5333999991416931},{"id":"https://openalex.org/keywords/absorption","display_name":"Absorption (acoustics)","score":0.37369999289512634},{"id":"https://openalex.org/keywords/in-vivo","display_name":"In vivo","score":0.36809998750686646},{"id":"https://openalex.org/keywords/temperature-measurement","display_name":"Temperature measurement","score":0.34299999475479126},{"id":"https://openalex.org/keywords/subcutaneous-tissue","display_name":"Subcutaneous tissue","score":0.32690000534057617}],"concepts":[{"id":"https://openalex.org/C84237751","wikidata":"https://www.wikidata.org/wiki/Q914138","display_name":"Specific absorption rate","level":3,"score":0.7304999828338623},{"id":"https://openalex.org/C44838205","wikidata":"https://www.wikidata.org/wiki/Q127995","display_name":"Microwave","level":2,"score":0.685699999332428},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.6678000092506409},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.644599974155426},{"id":"https://openalex.org/C2779949491","wikidata":"https://www.wikidata.org/wiki/Q242165","display_name":"Hyperthermia","level":2,"score":0.5333999991416931},{"id":"https://openalex.org/C125287762","wikidata":"https://www.wikidata.org/wiki/Q1758948","display_name":"Absorption (acoustics)","level":2,"score":0.37369999289512634},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.36809998750686646},{"id":"https://openalex.org/C72293138","wikidata":"https://www.wikidata.org/wiki/Q909741","display_name":"Temperature measurement","level":2,"score":0.34299999475479126},{"id":"https://openalex.org/C2777300098","wikidata":"https://www.wikidata.org/wiki/Q1164665","display_name":"Subcutaneous tissue","level":2,"score":0.32690000534057617},{"id":"https://openalex.org/C193493375","wikidata":"https://www.wikidata.org/wiki/Q1306232","display_name":"Penetration depth","level":2,"score":0.31700000166893005},{"id":"https://openalex.org/C80107235","wikidata":"https://www.wikidata.org/wiki/Q7162625","display_name":"Penetration (warfare)","level":2,"score":0.3068999946117401},{"id":"https://openalex.org/C204530211","wikidata":"https://www.wikidata.org/wiki/Q752823","display_name":"Thermal","level":2,"score":0.29789999127388},{"id":"https://openalex.org/C2164484","wikidata":"https://www.wikidata.org/wiki/Q5170150","display_name":"Core (optical fiber)","level":2,"score":0.2736999988555908},{"id":"https://openalex.org/C2909953478","wikidata":"https://www.wikidata.org/wiki/Q564872","display_name":"Hyperthermia Treatment","level":3,"score":0.26510000228881836},{"id":"https://openalex.org/C168068576","wikidata":"https://www.wikidata.org/wiki/Q190241","display_name":"Thermocouple","level":2,"score":0.2540000081062317}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/access.2025.3606940","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2025.3606940","pdf_url":null,"source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:7a6ca2e0f9dc436cac38e26007b082f7","is_oa":true,"landing_page_url":"https://doaj.org/article/7a6ca2e0f9dc436cac38e26007b082f7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 13, Pp 159334-159344 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2025.3606940","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2025.3606940","pdf_url":null,"source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G8898253571","display_name":null,"funder_award_id":"CRG/2022/002754","funder_id":"https://openalex.org/F4320320724","funder_display_name":"National Foundation for India"}],"funders":[{"id":"https://openalex.org/F4320320724","display_name":"National Foundation for India","ror":"https://ror.org/01vdmgn40"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1969464944","https://openalex.org/W2015187541","https://openalex.org/W2053428225","https://openalex.org/W2058794536","https://openalex.org/W2069528704","https://openalex.org/W2083927153","https://openalex.org/W2095493818","https://openalex.org/W2101312259","https://openalex.org/W2113041457","https://openalex.org/W2125612729","https://openalex.org/W2153628956","https://openalex.org/W2564536618","https://openalex.org/W2600452401","https://openalex.org/W2736998771","https://openalex.org/W2745725313","https://openalex.org/W2776355637","https://openalex.org/W2787945010","https://openalex.org/W3013701854","https://openalex.org/W3037300073","https://openalex.org/W3064998575","https://openalex.org/W3083922746","https://openalex.org/W3087412319","https://openalex.org/W3150277333","https://openalex.org/W3199059277","https://openalex.org/W4210625950","https://openalex.org/W4386261638","https://openalex.org/W4409223047"],"related_works":["https://openalex.org/W1988091614","https://openalex.org/W2537465405","https://openalex.org/W2911764982","https://openalex.org/W1680700295","https://openalex.org/W2366953982","https://openalex.org/W2384618613","https://openalex.org/W4205112216","https://openalex.org/W2078424453","https://openalex.org/W1520452347","https://openalex.org/W2536658601"],"abstract_inverted_index":{"A":[0,80],"small":[1,191],"animal":[2,192],"microwave":[3,27,32],"hyperthermia":[4],"(HT)":[5],"system":[6,19,76,134,185],"is":[7,135],"reported":[8],"for":[9,73,96,190],"preclinical":[10,133,184],"in":[11,100,139,172],"vivo":[12,161],"investigations":[13],"on":[14,195],"solid":[15,196],"tumors.":[16,197],"The":[17,183],"portable":[18],"consists":[20],"of":[21,107,120,131,147,153,169],"a":[22],"digitally":[23],"controlled":[24],"2.45":[25,92],"GHz":[26,93],"source":[28],"(1-30":[29],"W),":[30],"miniaturized":[31],"applicator":[33,84],"integrated":[34],"with":[35,43,63,103],"variable":[36],"volume":[37],"water":[38,40],"bolus,":[39],"circulation":[41],"module":[42,54],"flow":[44],"(35-125":[45],"ml/minute)":[46],"and":[47,58,65,70,78,114,129,150,175],"temperature":[48,167],"control":[49,77],"(15-45":[50],"\u00b0C),":[51],"precision":[52],"thermometry":[53],"to":[55],"monitor":[56],"subcutaneous":[57,173],"core":[59,176],"body":[60,177],"tissue":[61,102,140,174],"temperatures":[62],"\u00b10.06":[64],"\u00b10.08":[66],"\u00b0C":[67,171],"accuracy,":[68],"respectively,":[69],"user":[71],"interface":[72],"real":[74],"time":[75],"monitoring.":[79],"water-coupled":[81],"microstrip":[82],"dipole":[83],"(10.5":[85],"mm":[86,149],"\u00d7":[87],"10.5":[88],"mm)":[89],"resonating":[90],"at":[91],"was":[94],"optimized":[95],"localized":[97],"power":[98],"deposition":[99],"superficial":[101],"effective":[104],"field":[105],"size":[106],"149":[108],"<italic":[109,122,155],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[110,112,123,125,156,158],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">mm</i><sup":[111,124,157],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sup>":[113],"50%":[115],"specific":[116],"absorption":[117],"rate":[118],"coverage":[119,152],"973":[121],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">3</sup>.":[126,159],"Design,":[127],"construction":[128],"characterization":[130],"the":[132],"presented.":[136],"System":[137],"performance":[138],"mimicking":[141],"phantoms":[142],"indicated":[143],"thermal":[144],"penetration":[145],"depth":[146],"6.1":[148],"target":[151],"1379":[154],"In":[160],"HT":[162,193],"experiment":[163],"confirmed":[164],"steady":[165],"state":[166],"rise":[168,178],"4":[170],"less":[179],"than":[180],"1":[181],"\u00b0C.":[182],"characteristics":[186],"indicate":[187],"its":[188],"suitability":[189],"research":[194]},"counts_by_year":[],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}