{"id":"https://openalex.org/W4402124804","doi":"https://doi.org/10.1109/access.2024.3453039","title":"Two-Stage Approach With Combination of Outlier Detection Method and Deep Learning Enhances Automatic Epileptic Seizure Detection","display_name":"Two-Stage Approach With Combination of Outlier Detection Method and Deep Learning Enhances Automatic Epileptic Seizure Detection","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4402124804","doi":"https://doi.org/10.1109/access.2024.3453039"},"language":"en","primary_location":{"id":"doi:10.1109/access.2024.3453039","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2024.3453039","pdf_url":null,"source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1109/access.2024.3453039","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023699941","display_name":"Vadim Grubov","orcid":"https://orcid.org/0000-0003-2491-2592"},"institutions":[{"id":"https://openalex.org/I149643846","display_name":"Immanuel Kant Baltic Federal University","ror":"https://ror.org/0421w8947","country_code":"RU","type":"education","lineage":["https://openalex.org/I149643846"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vadim V. Grubov","raw_affiliation_strings":["Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia"],"raw_orcid":"https://orcid.org/0000-0003-2491-2592","affiliations":[{"raw_affiliation_string":"Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia","institution_ids":["https://openalex.org/I149643846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092904226","display_name":"Sergei Nazarikov","orcid":"https://orcid.org/0000-0002-7056-3373"},"institutions":[{"id":"https://openalex.org/I149643846","display_name":"Immanuel Kant Baltic Federal University","ror":"https://ror.org/0421w8947","country_code":"RU","type":"education","lineage":["https://openalex.org/I149643846"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Sergei I. Nazarikov","raw_affiliation_strings":["Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia"],"raw_orcid":"https://orcid.org/0000-0002-7056-3373","affiliations":[{"raw_affiliation_string":"Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia","institution_ids":["https://openalex.org/I149643846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025595136","display_name":"Semen Kurkin","orcid":"https://orcid.org/0000-0002-3438-5717"},"institutions":[{"id":"https://openalex.org/I149643846","display_name":"Immanuel Kant Baltic Federal University","ror":"https://ror.org/0421w8947","country_code":"RU","type":"education","lineage":["https://openalex.org/I149643846"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Semen A. Kurkin","raw_affiliation_strings":["Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia"],"raw_orcid":"https://orcid.org/0000-0002-3438-5717","affiliations":[{"raw_affiliation_string":"Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia","institution_ids":["https://openalex.org/I149643846"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113362190","display_name":"Nikita Utyashev","orcid":null},"institutions":[{"id":"https://openalex.org/I4210113199","display_name":"National Medical and Surgical Center named after N.I. Pirogov","ror":"https://ror.org/01v2h2d39","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210113199"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Nikita P. Utyashev","raw_affiliation_strings":["Pirogov National Medical and Surgical Center, Ministry of Health of the Russian Federation, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pirogov National Medical and Surgical Center, Ministry of Health of the Russian Federation, Moscow, Russia","institution_ids":["https://openalex.org/I4210113199","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012572362","display_name":"Denis A. Andrikov","orcid":"https://orcid.org/0000-0003-0359-0897"},"institutions":[{"id":"https://openalex.org/I4210158676","display_name":"Optolink (Russia)","ror":"https://ror.org/04a021880","country_code":"RU","type":"company","lineage":["https://openalex.org/I4210158676"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Denis A. Andrikov","raw_affiliation_strings":["Research and Production Company “Immersmed”, Moscow, Russia"],"raw_orcid":"https://orcid.org/0000-0003-0359-0897","affiliations":[{"raw_affiliation_string":"Research and Production Company “Immersmed”, Moscow, Russia","institution_ids":["https://openalex.org/I4210158676"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025137943","display_name":"\u041e \u042d \u041a\u0430\u0440\u043f\u043e\u0432","orcid":"https://orcid.org/0000-0002-5227-0657"},"institutions":[{"id":"https://openalex.org/I4210113199","display_name":"National Medical and Surgical Center named after N.I. Pirogov","ror":"https://ror.org/01v2h2d39","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210113199"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Oleg E. Karpov","raw_affiliation_strings":["Pirogov National Medical and Surgical Center, Ministry of Health of the Russian Federation, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pirogov National Medical and Surgical Center, Ministry of Health of the Russian Federation, Moscow, Russia","institution_ids":["https://openalex.org/I4210113199","https://openalex.org/I4210117042"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5019793174","display_name":"Alexander E. Hramov","orcid":"https://orcid.org/0000-0003-2787-2530"},"institutions":[{"id":"https://openalex.org/I149643846","display_name":"Immanuel Kant Baltic Federal University","ror":"https://ror.org/0421w8947","country_code":"RU","type":"education","lineage":["https://openalex.org/I149643846"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexander E. Hramov","raw_affiliation_strings":["Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia"],"raw_orcid":"https://orcid.org/0000-0003-2787-2530","affiliations":[{"raw_affiliation_string":"Baltic Center for Neurotechnology and Artificial Intelligence, Immanuel Kant Baltic Federal University, Kaliningrad, Russia","institution_ids":["https://openalex.org/I149643846"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":9.8407,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.98944303,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"12","issue":null,"first_page":"122168","last_page":"122182"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7137122750282288},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6766446828842163},{"id":"https://openalex.org/keywords/anomaly-detection","display_name":"Anomaly detection","score":0.6049439907073975},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.6016603112220764},{"id":"https://openalex.org/keywords/epileptic-seizure","display_name":"Epileptic seizure","score":0.581580638885498},{"id":"https://openalex.org/keywords/epilepsy","display_name":"Epilepsy","score":0.5617055892944336},{"id":"https://openalex.org/keywords/stage","display_name":"Stage (stratigraphy)","score":0.5483244061470032},{"id":"https://openalex.org/keywords/outlier","display_name":"Outlier","score":0.5249728560447693},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.49264079332351685},{"id":"https://openalex.org/keywords/feature-extraction","display_name":"Feature extraction","score":0.44479602575302124},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.09188419580459595}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7137122750282288},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6766446828842163},{"id":"https://openalex.org/C739882","wikidata":"https://www.wikidata.org/wiki/Q3560506","display_name":"Anomaly detection","level":2,"score":0.6049439907073975},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.6016603112220764},{"id":"https://openalex.org/C2779334592","wikidata":"https://www.wikidata.org/wiki/Q6279182","display_name":"Epileptic seizure","level":3,"score":0.581580638885498},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.5617055892944336},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5483244061470032},{"id":"https://openalex.org/C79337645","wikidata":"https://www.wikidata.org/wiki/Q779824","display_name":"Outlier","level":2,"score":0.5249728560447693},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.49264079332351685},{"id":"https://openalex.org/C52622490","wikidata":"https://www.wikidata.org/wiki/Q1026626","display_name":"Feature extraction","level":2,"score":0.44479602575302124},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.09188419580459595},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/access.2024.3453039","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2024.3453039","pdf_url":null,"source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:e3e3b0f4523f46a2977338c7fdcfff30","is_oa":true,"landing_page_url":"https://doaj.org/article/e3e3b0f4523f46a2977338c7fdcfff30","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 12, Pp 122168-122182 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2024.3453039","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2024.3453039","pdf_url":null,"source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5413433293","display_name":null,"funder_award_id":"23-71-30010","funder_id":"https://openalex.org/F4320324099","funder_display_name":"Russian Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320324099","display_name":"Russian Science Foundation","ror":"https://ror.org/03y2gwe85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":80,"referenced_works":["https://openalex.org/W32988189","https://openalex.org/W49331655","https://openalex.org/W611833001","https://openalex.org/W646783880","https://openalex.org/W1507181737","https://openalex.org/W1511504143","https://openalex.org/W1543660680","https://openalex.org/W1544107150","https://openalex.org/W1674341355","https://openalex.org/W1784118272","https://openalex.org/W2007221293","https://openalex.org/W2011714246","https://openalex.org/W2011957681","https://openalex.org/W2012547304","https://openalex.org/W2028034385","https://openalex.org/W2085281262","https://openalex.org/W2099169745","https://openalex.org/W2101383962","https://openalex.org/W2140792819","https://openalex.org/W2163195537","https://openalex.org/W2166073443","https://openalex.org/W2194775991","https://openalex.org/W2216946510","https://openalex.org/W2280217079","https://openalex.org/W2342822059","https://openalex.org/W2503583539","https://openalex.org/W2604469346","https://openalex.org/W2616872883","https://openalex.org/W2792365086","https://openalex.org/W2896329413","https://openalex.org/W2908954394","https://openalex.org/W2911761011","https://openalex.org/W2927351257","https://openalex.org/W2936503027","https://openalex.org/W2936774411","https://openalex.org/W2944126706","https://openalex.org/W2962858109","https://openalex.org/W2962957359","https://openalex.org/W2962984603","https://openalex.org/W2963355311","https://openalex.org/W2966680470","https://openalex.org/W2995459561","https://openalex.org/W3002927318","https://openalex.org/W3004612364","https://openalex.org/W3015647794","https://openalex.org/W3015929423","https://openalex.org/W3021503072","https://openalex.org/W3028393291","https://openalex.org/W3032515910","https://openalex.org/W3035485822","https://openalex.org/W3091163967","https://openalex.org/W3119307757","https://openalex.org/W3126317075","https://openalex.org/W3128482535","https://openalex.org/W3133353825","https://openalex.org/W3133716463","https://openalex.org/W3170569821","https://openalex.org/W3185122822","https://openalex.org/W3194668998","https://openalex.org/W3209313354","https://openalex.org/W4214650150","https://openalex.org/W4221067291","https://openalex.org/W4221090136","https://openalex.org/W4226178750","https://openalex.org/W4238337850","https://openalex.org/W4284887266","https://openalex.org/W4287660544","https://openalex.org/W4298168912","https://openalex.org/W4309268342","https://openalex.org/W4312240518","https://openalex.org/W4362471845","https://openalex.org/W4380784998","https://openalex.org/W4386566925","https://openalex.org/W6684191040","https://openalex.org/W6734171162","https://openalex.org/W6745609711","https://openalex.org/W6747381837","https://openalex.org/W6749290080","https://openalex.org/W6796912519","https://openalex.org/W6846643419"],"related_works":["https://openalex.org/W2395385109","https://openalex.org/W2773633178","https://openalex.org/W2499612753","https://openalex.org/W3111802945","https://openalex.org/W2946096271","https://openalex.org/W2295423552","https://openalex.org/W1598471830","https://openalex.org/W3107369729","https://openalex.org/W2363907062","https://openalex.org/W1981989525"],"abstract_inverted_index":{"Many":[0],"approaches":[1],"to":[2,21,36,111,129],"automated":[3],"epileptic":[4,68,134],"seizure":[5,32],"detection":[6,33,58],"share":[7],"a":[8,23,42,98,104,145,154],"common":[9],"challenge":[10],"\u2014":[11],"the":[12,48,73,88,91,130,137,150],"trade-off":[13],"between":[14],"recall":[15,102],"and":[16,83,95,127],"precision.":[17],"This":[18],"study":[19],"aims":[20],"develop":[22],"novel":[24],"approach":[25,152],"for":[26,46,80],"reducing":[27],"false":[28],"positive":[29],"predictions":[30],"in":[31,51,101,107,109],"tasks":[34],"applied":[35],"real-world":[37],"EEG":[38,69,81],"recordings.":[39],"We":[40,86,116],"propose":[41,144],"multi-stage":[43],"modeling":[44],"framework,":[45],"which":[47],"novelty":[49],"lies":[50],"combination":[52],"of":[53,90,133,140,149],"traditional":[54],"machine":[55],"learning":[56],"outlier":[57],"with":[59,123],"state-of-the-art":[60],"convolutional":[61],"neural":[62],"networks.":[63],"Our":[64],"dataset":[65],"includes":[66],"raw":[67],"data":[70],"directly":[71],"from":[72],"hospital.":[74],"Continuous":[75],"wavelet":[76],"analysis":[77],"is":[78],"employed":[79],"preprocessing":[82],"feature":[84],"extraction.":[85],"evaluated":[87],"performance":[89],"proposed":[92],"two-stage":[93],"algorithm,":[94],"it":[96],"demonstrated":[97],"slight":[99],"decrease":[100],"but":[103],"significant":[105],"improvement":[106],"precision":[108],"comparison":[110],"machine-learning-only":[112],"or":[113],"neural-network-only":[114],"algorithms.":[115],"hypothesize":[117],"that":[118],"this":[119],"finding":[120],"aligns":[121],"well":[122],"our":[124],"previous":[125],"research":[126],"relates":[128],"fundamental":[131],"properties":[132],"EEG,":[135],"including":[136],"extreme":[138],"behavior":[139],"seizures.":[141],"Finally,":[142],"we":[143],"potential":[146],"practical":[147],"application":[148],"developed":[151],"within":[153],"clinical":[155],"decision":[156],"support":[157],"system.":[158]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":7}],"updated_date":"2026-08-05T07:39:15.569665","created_date":"2025-10-10T00:00:00"}