{"id":"https://openalex.org/W4398151327","doi":"https://doi.org/10.1109/access.2024.3403246","title":"Optimized Magnetic Particle Navigation Based on Data-Driven Model for Enhanced Drug Targeting","display_name":"Optimized Magnetic Particle Navigation Based on Data-Driven Model for Enhanced Drug Targeting","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4398151327","doi":"https://doi.org/10.1109/access.2024.3403246"},"language":"en","primary_location":{"id":"doi:10.1109/access.2024.3403246","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2024.3403246","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/10535185.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/10535185.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078267695","display_name":"Rikkert Van Durme","orcid":"https://orcid.org/0000-0002-8424-6969"},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Rikkert Van Durme","raw_affiliation_strings":["Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-8424-6969","affiliations":[{"raw_affiliation_string":"Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067813287","display_name":"Guillaume Crevecoeur","orcid":"https://orcid.org/0000-0001-7630-8579"},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]},{"id":"https://openalex.org/I4210116480","display_name":"Flanders Make (Belgium)","ror":"https://ror.org/02ndjfz59","country_code":"BE","type":"company","lineage":["https://openalex.org/I4210116480"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Guillaume Crevecoeur","raw_affiliation_strings":["Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium","MIRO core lab Flanders Make, Lommel, Belgium"],"raw_orcid":"https://orcid.org/0000-0001-7630-8579","affiliations":[{"raw_affiliation_string":"Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"MIRO core lab Flanders Make, Lommel, Belgium","institution_ids":["https://openalex.org/I4210116480"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027140806","display_name":"Luc Dupr\u00e9","orcid":"https://orcid.org/0000-0002-0350-2810"},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Luc Dupr\u00e9","raw_affiliation_strings":["Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-0350-2810","affiliations":[{"raw_affiliation_string":"Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079013591","display_name":"Annelies Coene","orcid":"https://orcid.org/0000-0003-4280-8991"},"institutions":[{"id":"https://openalex.org/I32597200","display_name":"Ghent University","ror":"https://ror.org/00cv9y106","country_code":"BE","type":"education","lineage":["https://openalex.org/I32597200"]},{"id":"https://openalex.org/I4210116480","display_name":"Flanders Make (Belgium)","ror":"https://ror.org/02ndjfz59","country_code":"BE","type":"company","lineage":["https://openalex.org/I4210116480"]},{"id":"https://openalex.org/I4210118715","display_name":"Cancer Research Institute Ghent","ror":"https://ror.org/02afm7029","country_code":"BE","type":"facility","lineage":["https://openalex.org/I4210118715"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Annelies Coene","raw_affiliation_strings":["Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium","Cancer Research Institute Ghent, Ghent, Belgium","MIRO core lab Flanders Make, Lommel, Belgium"],"raw_orcid":"https://orcid.org/0000-0003-4280-8991","affiliations":[{"raw_affiliation_string":"Department of Electromechanical, Systems and Metal Engineering, Ghent University, Ghent, Belgium","institution_ids":["https://openalex.org/I32597200"]},{"raw_affiliation_string":"Cancer Research Institute Ghent, Ghent, Belgium","institution_ids":["https://openalex.org/I4210118715"]},{"raw_affiliation_string":"MIRO core lab Flanders Make, Lommel, Belgium","institution_ids":["https://openalex.org/I4210116480"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.1628,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.42725314,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"12","issue":null,"first_page":"71628","last_page":"71640"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12405","display_name":"Characterization and Applications of Magnetic Nanoparticles","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12405","display_name":"Characterization and Applications of Magnetic Nanoparticles","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11255","display_name":"Microfluidic and Bio-sensing Technologies","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12274","display_name":"Electrostatics and Colloid Interactions","score":0.991599977016449,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/particle","display_name":"Particle (ecology)","score":0.5431233644485474},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.541293740272522},{"id":"https://openalex.org/keywords/magnetic-particle-imaging","display_name":"Magnetic particle imaging","score":0.5055229663848877},{"id":"https://openalex.org/keywords/cluster","display_name":"Cluster (spacecraft)","score":0.47389641404151917},{"id":"https://openalex.org/keywords/magnetic-nanoparticles","display_name":"Magnetic nanoparticles","score":0.4518177807331085},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.3668960630893707},{"id":"https://openalex.org/keywords/aerospace-engineering","display_name":"Aerospace engineering","score":0.36513984203338623},{"id":"https://openalex.org/keywords/simulation","display_name":"Simulation","score":0.3517735004425049},{"id":"https://openalex.org/keywords/nanoparticle","display_name":"Nanoparticle","score":0.23104140162467957},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.17848190665245056}],"concepts":[{"id":"https://openalex.org/C2778517922","wikidata":"https://www.wikidata.org/wiki/Q7140482","display_name":"Particle (ecology)","level":2,"score":0.5431233644485474},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.541293740272522},{"id":"https://openalex.org/C140722275","wikidata":"https://www.wikidata.org/wiki/Q1884331","display_name":"Magnetic particle imaging","level":4,"score":0.5055229663848877},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.47389641404151917},{"id":"https://openalex.org/C87023908","wikidata":"https://www.wikidata.org/wiki/Q3870166","display_name":"Magnetic nanoparticles","level":3,"score":0.4518177807331085},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3668960630893707},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.36513984203338623},{"id":"https://openalex.org/C44154836","wikidata":"https://www.wikidata.org/wiki/Q45045","display_name":"Simulation","level":1,"score":0.3517735004425049},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.23104140162467957},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.17848190665245056},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/access.2024.3403246","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2024.3403246","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/10535185.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:archive.ugent.be:01HZ2H90GKAT1A0HKN0YKKRPVK","is_oa":true,"landing_page_url":"http://hdl.handle.net/1854/LU-01HZ2H90GKAT1A0HKN0YKKRPVK","pdf_url":"https://biblio.ugent.be/publication/01HZ2H90GKAT1A0HKN0YKKRPVK/file/01HZ2HE4ZBVPTADZZZ67NNMMWC.pdf","source":{"id":"https://openalex.org/S4306400478","display_name":"Ghent University Academic Bibliography (Ghent University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I32597200","host_organization_name":"Ghent University","host_organization_lineage":["https://openalex.org/I32597200"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 2169-3536","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:doaj.org/article:58d1578cef5242caa59f668fb6fd0a40","is_oa":true,"landing_page_url":"https://doaj.org/article/58d1578cef5242caa59f668fb6fd0a40","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 12, Pp 71628-71640 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2024.3403246","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2024.3403246","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/10535185.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.7799999713897705,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G3292089550","display_name":null,"funder_award_id":"12Z4722N","funder_id":"https://openalex.org/F4320321730","funder_display_name":"Fonds Wetenschappelijk Onderzoek"}],"funders":[{"id":"https://openalex.org/F4320321730","display_name":"Fonds Wetenschappelijk Onderzoek","ror":"https://ror.org/03qtxy027"},{"id":"https://openalex.org/F4320327336","display_name":"Vlaamse regering","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4398151327.pdf","grobid_xml":"https://content.openalex.org/works/W4398151327.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W149158121","https://openalex.org/W1534541040","https://openalex.org/W1557466162","https://openalex.org/W1582919213","https://openalex.org/W1621033879","https://openalex.org/W1801840020","https://openalex.org/W1964262460","https://openalex.org/W1970766032","https://openalex.org/W1979723863","https://openalex.org/W1980226491","https://openalex.org/W1983067755","https://openalex.org/W1983277479","https://openalex.org/W1984672166","https://openalex.org/W1986524396","https://openalex.org/W1987312809","https://openalex.org/W2009562337","https://openalex.org/W2011867361","https://openalex.org/W2019104037","https://openalex.org/W2023413997","https://openalex.org/W2050883740","https://openalex.org/W2073221244","https://openalex.org/W2075665712","https://openalex.org/W2090480913","https://openalex.org/W2111406701","https://openalex.org/W2117918852","https://openalex.org/W2123849267","https://openalex.org/W2152001041","https://openalex.org/W2323913943","https://openalex.org/W2410625365","https://openalex.org/W2480295938","https://openalex.org/W2527610710","https://openalex.org/W2588306107","https://openalex.org/W2609770201","https://openalex.org/W2753088950","https://openalex.org/W2898728094","https://openalex.org/W2898761039","https://openalex.org/W2902965611","https://openalex.org/W2905651950","https://openalex.org/W2909385265","https://openalex.org/W2963784430","https://openalex.org/W2964191637","https://openalex.org/W2990777873","https://openalex.org/W3004533775","https://openalex.org/W3016784457","https://openalex.org/W3081104726","https://openalex.org/W3090684135","https://openalex.org/W3101746462","https://openalex.org/W3108937705","https://openalex.org/W3110090374","https://openalex.org/W3115129838","https://openalex.org/W3209965475","https://openalex.org/W4213275549","https://openalex.org/W4225166029","https://openalex.org/W4243637876","https://openalex.org/W4280598010","https://openalex.org/W4286669545","https://openalex.org/W4286781802","https://openalex.org/W4293094899","https://openalex.org/W4294891511","https://openalex.org/W4301014524","https://openalex.org/W4312065614","https://openalex.org/W4316038987","https://openalex.org/W4379184233","https://openalex.org/W6631979330"],"related_works":["https://openalex.org/W4239310695","https://openalex.org/W3165454691","https://openalex.org/W2112281092","https://openalex.org/W2002220930","https://openalex.org/W1505178550","https://openalex.org/W2091017237","https://openalex.org/W2015976998","https://openalex.org/W2074714886","https://openalex.org/W2897880527","https://openalex.org/W3099439648"],"abstract_inverted_index":{"Targeted":[0],"drug":[1,158],"delivery":[2],"by":[3],"magnetically":[4],"steering":[5],"micro-":[6],"and":[7,30,53,86,143,165],"nanoparticles":[8],"for":[9,95],"specified":[10],"therapy":[11],"is":[12,79,102],"gaining":[13],"ground":[14],"in":[15,56,73,104,114,150],"the":[16,44,96,99,111,151],"field":[17],"of":[18,46],"medical":[19],"treatments.":[20],"Yet":[21],"fundamental":[22],"challenges":[23],"with":[24],"regards":[25],"to":[26,42,81,109,124,168],"modeling":[27,41],"particle":[28,48,91,112,146],"movement":[29],"reaching":[31],"desired":[32],"regions":[33],"exist.":[34],"In":[35],"this":[36,77],"work,":[37],"we":[38],"use":[39],"data-driven":[40,100],"predict":[43],"velocities":[45],"a":[47,68,82,115,125],"cluster":[49,92],"from":[50,121],"its":[51,169],"positions":[52],"electromagnet":[54],"currents":[55],"an":[57,122],"<italic":[58],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[59],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">in-vitro</i>":[60],"targeting":[61,159],"setup.":[62,153],"This":[63],"explicit":[64],"velocity":[65,113],"prediction":[66],"using":[67],"neural":[69],"network,":[70],"not":[71],"found":[72],"previous":[74],"works":[75],"on":[76],"topic,":[78],"compared":[80],"state-of-the-art":[83],"physics-based":[84],"model,":[85],"produced":[87],"more":[88,163],"accurate":[89,164],"estimated":[90],"trajectories.":[93],"Furthermore,":[94],"first":[97],"time,":[98],"model":[101],"integrated":[103],"model-based":[105],"optimization":[106],"methods":[107],"designed":[108],"maximize":[110],"predefined":[116],"direction,":[117],"or":[118],"guide":[119],"particles":[120],"initial":[123],"final":[126],"position":[127],"under":[128],"minimized":[129],"energy":[130],"dissipation":[131],"taking":[132],"into":[133],"account":[134],"future":[135],"time":[136],"steps":[137],"without":[138],"requiring":[139],"real-time":[140],"feedback.":[141],"Simulated":[142],"measured":[144],"optimized":[145],"trajectories":[147],"strongly":[148],"overlap":[149],"experimental":[152],"With":[154],"these":[155],"findings,":[156],"magnetic":[157],"can":[160],"be":[161],"made":[162],"brought":[166],"closer":[167],"clinical":[170],"implementation.":[171]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}