{"id":"https://openalex.org/W4293057275","doi":"https://doi.org/10.1109/access.2022.3201543","title":"Geometric Deep Learning for Protein\u2013Protein Interaction Predictions","display_name":"Geometric Deep Learning for Protein\u2013Protein Interaction Predictions","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4293057275","doi":"https://doi.org/10.1109/access.2022.3201543"},"language":"en","primary_location":{"id":"doi:10.1109/access.2022.3201543","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3201543","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/09866765.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/09866765.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086061878","display_name":"Gabriel St-Pierre-Lemieux","orcid":"https://orcid.org/0000-0002-8985-4920"},"institutions":[{"id":"https://openalex.org/I4210159778","display_name":"National Research Council Canada","ror":"https://ror.org/04mte1k06","country_code":"CA","type":"government","lineage":["https://openalex.org/I4210159778"]},{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Gabriel St-Pierre Lemieux","raw_affiliation_strings":["National Research Council Canada, Ottawa, ON, Canada","University of Ottawa, 800 King Edward Avenue, Ottawa, Ontario, Canada","National Research Council Canada, 1200 Montreal Road, Ottawa, Ontario, Canada"],"affiliations":[{"raw_affiliation_string":"National Research Council Canada, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I4210159778"]},{"raw_affiliation_string":"University of Ottawa, 800 King Edward Avenue, Ottawa, Ontario, Canada","institution_ids":["https://openalex.org/I153718931"]},{"raw_affiliation_string":"National Research Council Canada, 1200 Montreal Road, Ottawa, Ontario, Canada","institution_ids":["https://openalex.org/I4210159778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038613507","display_name":"Eric Paquet","orcid":"https://orcid.org/0000-0001-6515-2556"},"institutions":[{"id":"https://openalex.org/I4210159778","display_name":"National Research Council Canada","ror":"https://ror.org/04mte1k06","country_code":"CA","type":"government","lineage":["https://openalex.org/I4210159778"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Eric Paquet","raw_affiliation_strings":["National Research Council Canada, Ottawa, ON, Canada","National Research Council Canada, 1200 Montreal Road, Ottawa, Ontario, Canada"],"affiliations":[{"raw_affiliation_string":"National Research Council Canada, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I4210159778"]},{"raw_affiliation_string":"National Research Council Canada, 1200 Montreal Road, Ottawa, Ontario, Canada","institution_ids":["https://openalex.org/I4210159778"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069410082","display_name":"Herna L. Viktor","orcid":"https://orcid.org/0000-0003-1914-5077"},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Herna L Viktor","raw_affiliation_strings":["School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON, Canada"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I153718931"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003147487","display_name":"Wojtek Michalowski","orcid":"https://orcid.org/0000-0002-9198-6439"},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Wojtek Michalowski","raw_affiliation_strings":["School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON, Canada"],"affiliations":[{"raw_affiliation_string":"School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I153718931"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5086061878"],"corresponding_institution_ids":["https://openalex.org/I153718931","https://openalex.org/I4210159778"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":1.0526,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.79562578,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"10","issue":null,"first_page":"90045","last_page":"90055"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9671000242233276,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9671000242233276,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.95660001039505,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.955299973487854,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6535679697990417},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.44336622953414917}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6535679697990417},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.44336622953414917}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/access.2022.3201543","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3201543","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/09866765.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:cisti-icist.nrc-cnrc.ca:cistinparc:6615a79a-66fc-4640-881f-9aa94c806c3e","is_oa":true,"landing_page_url":"https://nrc-publications.canada.ca/eng/view/object/?id=6615a79a-66fc-4640-881f-9aa94c806c3e","pdf_url":"https://nrc-publications.canada.ca/eng/view/ft/?id=6615a79a-66fc-4640-881f-9aa94c806c3e","source":{"id":"https://openalex.org/S7407055245","display_name":"NPARC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:339ca760f1014f05be3c335866866057","is_oa":true,"landing_page_url":"https://doaj.org/article/339ca760f1014f05be3c335866866057","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 10, Pp 90045-90055 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2022.3201543","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3201543","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/6514899/09866765.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4293057275.pdf","grobid_xml":"https://content.openalex.org/works/W4293057275.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1979601325","https://openalex.org/W2045990223","https://openalex.org/W2091791686","https://openalex.org/W2094997686","https://openalex.org/W2100657858","https://openalex.org/W2105525514","https://openalex.org/W2130479394","https://openalex.org/W2131562240","https://openalex.org/W2158698691","https://openalex.org/W2412589610","https://openalex.org/W2558460151","https://openalex.org/W2558748708","https://openalex.org/W2583907533","https://openalex.org/W2624968853","https://openalex.org/W2783165089","https://openalex.org/W2786055572","https://openalex.org/W2802799492","https://openalex.org/W2809890174","https://openalex.org/W2885329520","https://openalex.org/W2888689618","https://openalex.org/W2900437486","https://openalex.org/W2948151656","https://openalex.org/W2951679282","https://openalex.org/W2963021451","https://openalex.org/W2966916628","https://openalex.org/W2979609031","https://openalex.org/W2992752586","https://openalex.org/W2996403968","https://openalex.org/W2998620327","https://openalex.org/W3008354258","https://openalex.org/W3035965352","https://openalex.org/W3082306291","https://openalex.org/W3099878876","https://openalex.org/W3100159300","https://openalex.org/W3122807430","https://openalex.org/W3124903422","https://openalex.org/W3137391901","https://openalex.org/W3141776272","https://openalex.org/W3157130577","https://openalex.org/W3162082122","https://openalex.org/W3196410189","https://openalex.org/W4200625991","https://openalex.org/W4212774754","https://openalex.org/W4213430676","https://openalex.org/W4214598159","https://openalex.org/W4224882649","https://openalex.org/W4225433946","https://openalex.org/W4246219036","https://openalex.org/W4293003482","https://openalex.org/W6743410771","https://openalex.org/W6765474767"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"This":[0],"work":[1],"introduces":[2],"novel":[3,72],"approaches,":[4],"based":[5,60],"on":[6,61],"geometrical":[7],"deep":[8],"learning,":[9],"for":[10],"predicting":[11],"protein–protein":[12],"interactions.":[13],"A":[14],"dataset":[15],"containing":[16],"both":[17],"interacting":[18],"and":[19,46,56,70,84],"non-interacting":[20],"proteins":[21],"is":[22],"selected":[23],"from":[24,31],"the":[25,35,82,85,88],"Negatome":[26],"Database.":[27],"Interactions":[28],"are":[29,42,54,59],"predicted":[30],"a":[32,71],"graph":[33,62],"representing":[34],"proteins’":[36],"three-dimensional":[37],"macromolecular":[38],"surfaces.":[39],"The":[40,78],"nodes":[41],"described":[43],"with":[44],"heat":[45],"wave":[47],"kernel":[48],"signatures.":[49],"Twenty-one":[50],"neural":[51,64,68,76],"network":[52],"architectures":[53],"proposed":[55,89],"compared;":[57],"these":[58],"convolutional":[63,67,75],"networks,":[65,69],"spectral":[66],"spatio–spectral":[73],"spatialized-gated":[74],"network.":[77],"experimental":[79],"results":[80],"demonstrate":[81],"accuracy":[83],"efficiency":[86],"of":[87],"architectures.":[90]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3}],"updated_date":"2026-03-08T08:50:53.379069","created_date":"2025-10-10T00:00:00"}