{"id":"https://openalex.org/W4214902899","doi":"https://doi.org/10.1109/access.2022.3156964","title":"Detection of Oculomotor Dysmetria From Mobile Phone Video of the Horizontal Saccades Task Using Signal Processing and Machine Learning Approaches","display_name":"Detection of Oculomotor Dysmetria From Mobile Phone Video of the Horizontal Saccades Task Using Signal Processing and Machine Learning Approaches","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4214902899","doi":"https://doi.org/10.1109/access.2022.3156964"},"language":"en","primary_location":{"id":"doi:10.1109/access.2022.3156964","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3156964","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09729204.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09729204.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080730972","display_name":"Hamed Azami","orcid":"https://orcid.org/0000-0001-7612-0840"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hamed Azami","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-7612-0840","affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050824458","display_name":"Zhuoqing Chang","orcid":"https://orcid.org/0000-0001-5766-3129"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhuoqing Chang","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA"],"raw_orcid":"https://orcid.org/0000-0001-5766-3129","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088881304","display_name":"Steven E. Arnold","orcid":"https://orcid.org/0000-0002-9487-415X"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven E. Arnold","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025218580","display_name":"Guillermo Sapiro","orcid":"https://orcid.org/0000-0001-9190-6964"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guillermo Sapiro","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA"],"raw_orcid":"https://orcid.org/0000-0001-9190-6964","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066477003","display_name":"Anoopum S. Gupta","orcid":"https://orcid.org/0000-0002-8741-0621"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anoopum S. Gupta","raw_affiliation_strings":["Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8741-0621","affiliations":[{"raw_affiliation_string":"Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5080730972"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":1.7178,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.82979679,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"10","issue":null,"first_page":"34022","last_page":"34031"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10949","display_name":"Genetic Neurodegenerative Diseases","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10949","display_name":"Genetic Neurodegenerative Diseases","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10542","display_name":"Vestibular and auditory disorders","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dysmetria","display_name":"Dysmetria","score":0.9259397983551025},{"id":"https://openalex.org/keywords/eye-movement","display_name":"Eye movement","score":0.7012537717819214},{"id":"https://openalex.org/keywords/saccade","display_name":"Saccade","score":0.6396386623382568},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6215476393699646},{"id":"https://openalex.org/keywords/saccadic-masking","display_name":"Saccadic masking","score":0.58503258228302},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.516149640083313},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4676717519760132},{"id":"https://openalex.org/keywords/ataxia","display_name":"Ataxia","score":0.3736320734024048},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.30738094449043274},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.25684690475463867}],"concepts":[{"id":"https://openalex.org/C2777154897","wikidata":"https://www.wikidata.org/wiki/Q517183","display_name":"Dysmetria","level":3,"score":0.9259397983551025},{"id":"https://openalex.org/C153050134","wikidata":"https://www.wikidata.org/wiki/Q760256","display_name":"Eye movement","level":2,"score":0.7012537717819214},{"id":"https://openalex.org/C2779524336","wikidata":"https://www.wikidata.org/wiki/Q369503","display_name":"Saccade","level":3,"score":0.6396386623382568},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6215476393699646},{"id":"https://openalex.org/C11054436","wikidata":"https://www.wikidata.org/wiki/Q7396580","display_name":"Saccadic masking","level":3,"score":0.58503258228302},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.516149640083313},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4676717519760132},{"id":"https://openalex.org/C2780906641","wikidata":"https://www.wikidata.org/wiki/Q213373","display_name":"Ataxia","level":2,"score":0.3736320734024048},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.30738094449043274},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.25684690475463867}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/access.2022.3156964","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3156964","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09729204.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:552f162853014e9aaa165d8772b8aa7b","is_oa":false,"landing_page_url":"https://doaj.org/article/552f162853014e9aaa165d8772b8aa7b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 10, Pp 34022-34031 (2022)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9632643","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9632643","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1109/access.2022.3156964","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3156964","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09729204.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4000000059604645,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G1917831563","display_name":null,"funder_award_id":"R01 NS117826","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8288036582","display_name":null,"funder_award_id":"NIH R01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320308604","display_name":"Biogen","ror":"https://ror.org/02jqkb192"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4214902899.pdf","grobid_xml":"https://content.openalex.org/works/W4214902899.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W49405022","https://openalex.org/W1590583843","https://openalex.org/W1862394037","https://openalex.org/W1970554175","https://openalex.org/W1981469493","https://openalex.org/W1988949556","https://openalex.org/W1990650190","https://openalex.org/W1994233698","https://openalex.org/W2005076053","https://openalex.org/W2011271221","https://openalex.org/W2013112874","https://openalex.org/W2023852274","https://openalex.org/W2030215259","https://openalex.org/W2035949382","https://openalex.org/W2043288745","https://openalex.org/W2049166497","https://openalex.org/W2049288682","https://openalex.org/W2059851411","https://openalex.org/W2061564920","https://openalex.org/W2068346015","https://openalex.org/W2074272312","https://openalex.org/W2077770566","https://openalex.org/W2089468765","https://openalex.org/W2089907761","https://openalex.org/W2105954114","https://openalex.org/W2107026277","https://openalex.org/W2109394932","https://openalex.org/W2133701212","https://openalex.org/W2156770021","https://openalex.org/W2158762743","https://openalex.org/W2165061769","https://openalex.org/W2254832494","https://openalex.org/W2273310283","https://openalex.org/W2333775360","https://openalex.org/W2401583684","https://openalex.org/W2405502762","https://openalex.org/W2410294782","https://openalex.org/W2475082964","https://openalex.org/W2545978864","https://openalex.org/W2579919920","https://openalex.org/W2588033460","https://openalex.org/W2606911774","https://openalex.org/W2610099500","https://openalex.org/W2747198643","https://openalex.org/W2767298146","https://openalex.org/W2778932222","https://openalex.org/W2788741349","https://openalex.org/W2790654419","https://openalex.org/W2792354770","https://openalex.org/W2795761008","https://openalex.org/W2802495352","https://openalex.org/W2904107915","https://openalex.org/W2917255080","https://openalex.org/W2917347002","https://openalex.org/W2954277648","https://openalex.org/W2964070924","https://openalex.org/W2989772842","https://openalex.org/W3013265159","https://openalex.org/W3034594684","https://openalex.org/W3039321039","https://openalex.org/W3086471466","https://openalex.org/W3096726666","https://openalex.org/W3105474450","https://openalex.org/W3162420261","https://openalex.org/W4231082634","https://openalex.org/W6714917096","https://openalex.org/W6745148249","https://openalex.org/W7074101622"],"related_works":["https://openalex.org/W2024450011","https://openalex.org/W4377940789","https://openalex.org/W2075247165","https://openalex.org/W4311556462","https://openalex.org/W2144512311","https://openalex.org/W2020028422","https://openalex.org/W4322720324","https://openalex.org/W2079218653","https://openalex.org/W4242213386","https://openalex.org/W2050973097"],"abstract_inverted_index":{"Eye":[0,58],"movement":[1,59],"assessments":[2,234],"have":[3],"the":[4,68,134,150,181],"potential":[5],"to":[6,87,133,146,159,191,202],"help":[7],"in":[8,22,39,76,101,126,157,205,238],"diagnosis":[9],"and":[10,19,26,32,54,78,83,112,148,163,174,186,210,229,242],"tracking":[11],"of":[12,67,93,137,152,183,194,199,223,235],"neurological":[13],"disorders.":[14],"Cerebellar":[15],"ataxias":[16],"cause":[17],"profound":[18],"characteristic":[20],"abnormalities":[21],"smooth":[23],"pursuit,":[24],"saccades,":[25,195],"fixation.":[27],"Oculomotor":[28],"dysmetria":[29,107,129,204],"(i.e.,":[30],"hypermetric":[31],"hypometric":[33],"saccades)":[34],"is":[35],"a":[36,49,220,224],"common":[37],"finding":[38],"individuals":[40,103,161],"with":[41,80,104,106,109,162],"cerebellar":[42],"ataxia.":[43,206],"In":[44],"this":[45,208],"study,":[46],"we":[47],"evaluated":[48],"scalable":[50,211],"approach":[51,212],"for":[52,197,213,227],"detecting":[53],"quantifying":[55],"oculomotor":[56,165,203,216,236],"dysmetria.":[57,116,166],"data":[60],"were":[61,98,130],"extracted":[62],"from":[63],"iPhone":[64,192],"video":[65,193],"recordings":[66],"horizontal":[69],"saccade":[70,89],"task":[71,75],"(a":[72],"standard":[73],"clinical":[74,243],"ataxia)":[77],"combined":[79],"signal":[81,154,184],"processing":[82,155,185],"machine":[84,142,187],"learning":[85,188],"approaches":[86,189],"quantify":[88],"abnormalities.":[90],"Entropy-based":[91],"measures":[92],"eye":[94,124],"movements":[95,125],"during":[96],"saccades":[97],"significantly":[99],"different":[100],"72":[102],"ataxia":[105,111,228],"compared":[108],"80":[110],"Parkinson\u2019s":[113],"participants":[114],"without":[115,128,164],"A":[117,139],"template":[118,136],"matching-based":[119],"analysis":[120],"demonstrated":[121],"that":[122,180],"saccadic":[123],"patients":[127],"more":[131],"similar":[132],"ideal":[135],"saccades.":[138],"support":[140],"vector":[141],"was":[143],"then":[144],"used":[145],"train":[147],"test":[149],"ability":[151],"multiple":[153],"features":[156],"combination":[158,182],"distinguish":[160],"The":[167],"model":[168],"achieved":[169],"78%":[170],"accuracy":[171],"(sensitivity=":[172],"80%":[173],"specificity=":[175],"76%).":[176],"These":[177],"results":[178],"show":[179],"applied":[190],"allow":[196,231],"extraction":[198],"information":[200,217],"pertaining":[201],"Overall,":[207],"inexpensive":[209],"capturing":[214],"important":[215],"may":[218],"be":[219],"useful":[221],"component":[222],"screening":[225],"tool":[226],"could":[230],"frequent":[232],"at-home":[233],"function":[237],"natural":[239],"history":[240],"studies":[241],"trials.":[244]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":2}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2022-03-05T00:00:00"}
