{"id":"https://openalex.org/W4210598545","doi":"https://doi.org/10.1109/access.2022.3146312","title":"A Survey of Machine Learning Approaches Applied to Gene Expression Analysis for Cancer Prediction","display_name":"A Survey of Machine Learning Approaches Applied to Gene Expression Analysis for Cancer Prediction","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4210598545","doi":"https://doi.org/10.1109/access.2022.3146312"},"language":"en","primary_location":{"id":"doi:10.1109/access.2022.3146312","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3146312","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09693112.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09693112.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025746154","display_name":"Mahmood Khalsan","orcid":"https://orcid.org/0000-0003-0398-5880"},"institutions":[{"id":"https://openalex.org/I166455938","display_name":"University of Babylon","ror":"https://ror.org/0170edc15","country_code":"IQ","type":"education","lineage":["https://openalex.org/I166455938"]},{"id":"https://openalex.org/I35870678","display_name":"University of Northampton","ror":"https://ror.org/04jp2hx10","country_code":"GB","type":"education","lineage":["https://openalex.org/I35870678"]}],"countries":["GB","IQ"],"is_corresponding":true,"raw_author_name":"Mahmood Khalsan","raw_affiliation_strings":["Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","Computer Science Department, College of Information Technology, University of Babylon, Babil, Iraq"],"raw_orcid":"https://orcid.org/0000-0003-0398-5880","affiliations":[{"raw_affiliation_string":"Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","institution_ids":["https://openalex.org/I35870678"]},{"raw_affiliation_string":"Computer Science Department, College of Information Technology, University of Babylon, Babil, Iraq","institution_ids":["https://openalex.org/I166455938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032870666","display_name":"Lee R. Machado","orcid":"https://orcid.org/0000-0001-7974-2178"},"institutions":[{"id":"https://openalex.org/I35870678","display_name":"University of Northampton","ror":"https://ror.org/04jp2hx10","country_code":"GB","type":"education","lineage":["https://openalex.org/I35870678"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Lee R. Machado","raw_affiliation_strings":["Centre for Physical Activity and Life Science, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K"],"raw_orcid":"https://orcid.org/0000-0001-7974-2178","affiliations":[{"raw_affiliation_string":"Centre for Physical Activity and Life Science, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","institution_ids":["https://openalex.org/I35870678"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062494803","display_name":"Eman S. Al-Shamery","orcid":"https://orcid.org/0000-0002-3138-7629"},"institutions":[{"id":"https://openalex.org/I166455938","display_name":"University of Babylon","ror":"https://ror.org/0170edc15","country_code":"IQ","type":"education","lineage":["https://openalex.org/I166455938"]}],"countries":["IQ"],"is_corresponding":false,"raw_author_name":"Eman Salih Al-Shamery","raw_affiliation_strings":["Computer Science Department, College of Information Technology, University of Babylon, Babil, Iraq"],"raw_orcid":"https://orcid.org/0000-0002-3138-7629","affiliations":[{"raw_affiliation_string":"Computer Science Department, College of Information Technology, University of Babylon, Babil, Iraq","institution_ids":["https://openalex.org/I166455938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008386824","display_name":"Suraj Ajit","orcid":"https://orcid.org/0000-0001-7603-570X"},"institutions":[{"id":"https://openalex.org/I35870678","display_name":"University of Northampton","ror":"https://ror.org/04jp2hx10","country_code":"GB","type":"education","lineage":["https://openalex.org/I35870678"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Suraj Ajit","raw_affiliation_strings":["Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K"],"raw_orcid":"https://orcid.org/0000-0001-7603-570X","affiliations":[{"raw_affiliation_string":"Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","institution_ids":["https://openalex.org/I35870678"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070809010","display_name":"Karen Anthony","orcid":"https://orcid.org/0000-0002-3638-2405"},"institutions":[{"id":"https://openalex.org/I35870678","display_name":"University of Northampton","ror":"https://ror.org/04jp2hx10","country_code":"GB","type":"education","lineage":["https://openalex.org/I35870678"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Karen Anthony","raw_affiliation_strings":["Centre for Physical Activity and Life Science, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K"],"raw_orcid":"https://orcid.org/0000-0002-3638-2405","affiliations":[{"raw_affiliation_string":"Centre for Physical Activity and Life Science, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","institution_ids":["https://openalex.org/I35870678"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101598888","display_name":"Mu Mu","orcid":"https://orcid.org/0000-0003-1931-7959"},"institutions":[{"id":"https://openalex.org/I35870678","display_name":"University of Northampton","ror":"https://ror.org/04jp2hx10","country_code":"GB","type":"education","lineage":["https://openalex.org/I35870678"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mu Mu","raw_affiliation_strings":["Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K"],"raw_orcid":"https://orcid.org/0000-0003-1931-7959","affiliations":[{"raw_affiliation_string":"Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","institution_ids":["https://openalex.org/I35870678"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035218478","display_name":"Michael Opoku Agyeman","orcid":"https://orcid.org/0000-0002-3734-4451"},"institutions":[{"id":"https://openalex.org/I35870678","display_name":"University of Northampton","ror":"https://ror.org/04jp2hx10","country_code":"GB","type":"education","lineage":["https://openalex.org/I35870678"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Michael Opoku Agyeman","raw_affiliation_strings":["Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K"],"raw_orcid":"https://orcid.org/0000-0002-3734-4451","affiliations":[{"raw_affiliation_string":"Centre for Advanced and Smart Technologies, Faculty of Arts, Science and Technology, University of Northampton, Northampton, U.K","institution_ids":["https://openalex.org/I35870678"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5025746154"],"corresponding_institution_ids":["https://openalex.org/I166455938","https://openalex.org/I35870678"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":7.638,"has_fulltext":true,"cited_by_count":94,"citation_normalized_percentile":{"value":0.98378029,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"10","issue":null,"first_page":"27522","last_page":"27534"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9934999942779541,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9876000285148621,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biomarker-discovery","display_name":"Biomarker discovery","score":0.5854303240776062},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.5823796987533569},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.5543538331985474},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.5447611808776855},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5387812852859497},{"id":"https://openalex.org/keywords/cancer-biomarkers","display_name":"Cancer biomarkers","score":0.4937785565853119},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4610404670238495},{"id":"https://openalex.org/keywords/microarray-analysis-techniques","display_name":"Microarray analysis techniques","score":0.45023900270462036},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4302394688129425},{"id":"https://openalex.org/keywords/kidney-cancer","display_name":"Kidney cancer","score":0.41467082500457764},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.40568143129348755},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.4035269320011139},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3720356822013855},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.34408843517303467},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2803109288215637},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2171531617641449},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.14593073725700378},{"id":"https://openalex.org/keywords/proteomics","display_name":"Proteomics","score":0.1267111897468567},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.08185276389122009}],"concepts":[{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.5854303240776062},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5823796987533569},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5543538331985474},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5447611808776855},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5387812852859497},{"id":"https://openalex.org/C2777002142","wikidata":"https://www.wikidata.org/wiki/Q5031432","display_name":"Cancer biomarkers","level":3,"score":0.4937785565853119},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4610404670238495},{"id":"https://openalex.org/C8415881","wikidata":"https://www.wikidata.org/wiki/Q6839217","display_name":"Microarray analysis techniques","level":4,"score":0.45023900270462036},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4302394688129425},{"id":"https://openalex.org/C2781068499","wikidata":"https://www.wikidata.org/wiki/Q3242950","display_name":"Kidney cancer","level":3,"score":0.41467082500457764},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.40568143129348755},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.4035269320011139},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3720356822013855},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.34408843517303467},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2803109288215637},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2171531617641449},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14593073725700378},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.1267111897468567},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08185276389122009},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1109/access.2022.3146312","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3146312","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09693112.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:nectar.northampton.ac.uk:15965","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4377196393","display_name":"NECTAR - Northampton Electronic Collection of Thesis and Research (University of Northampton)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I35870678","host_organization_name":"University of Northampton","host_organization_lineage":["https://openalex.org/I35870678"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:c29344e941a44159942c0d83f55dcc04","is_oa":true,"landing_page_url":"https://doaj.org/article/c29344e941a44159942c0d83f55dcc04","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 10, Pp 27522-27534 (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2022.3146312","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2022.3146312","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/9668973/09693112.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4099999964237213,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4210598545.pdf","grobid_xml":"https://content.openalex.org/works/W4210598545.grobid-xml"},"referenced_works_count":70,"referenced_works":["https://openalex.org/W1490257054","https://openalex.org/W1543960810","https://openalex.org/W1570296396","https://openalex.org/W2020541351","https://openalex.org/W2046759180","https://openalex.org/W2052964740","https://openalex.org/W2064325393","https://openalex.org/W2080837438","https://openalex.org/W2153601733","https://openalex.org/W2155796846","https://openalex.org/W2158485828","https://openalex.org/W2180481128","https://openalex.org/W2193170334","https://openalex.org/W2230939080","https://openalex.org/W2275877493","https://openalex.org/W2289863546","https://openalex.org/W2292445745","https://openalex.org/W2516938563","https://openalex.org/W2544039468","https://openalex.org/W2555803041","https://openalex.org/W2566743738","https://openalex.org/W2601394963","https://openalex.org/W2601710247","https://openalex.org/W2610918181","https://openalex.org/W2614424865","https://openalex.org/W2755012395","https://openalex.org/W2766600422","https://openalex.org/W2770690579","https://openalex.org/W2773863882","https://openalex.org/W2786486208","https://openalex.org/W2790137849","https://openalex.org/W2791015340","https://openalex.org/W2791756735","https://openalex.org/W2803520432","https://openalex.org/W2803773316","https://openalex.org/W2803881474","https://openalex.org/W2809265185","https://openalex.org/W2885614550","https://openalex.org/W2886415518","https://openalex.org/W2893684021","https://openalex.org/W2898321887","https://openalex.org/W2899235613","https://openalex.org/W2902217684","https://openalex.org/W2903461962","https://openalex.org/W2903805501","https://openalex.org/W2904997929","https://openalex.org/W2906508336","https://openalex.org/W2909239315","https://openalex.org/W2911854833","https://openalex.org/W2912300303","https://openalex.org/W2912520033","https://openalex.org/W2919115771","https://openalex.org/W2920795615","https://openalex.org/W2949151272","https://openalex.org/W2950246742","https://openalex.org/W2954499361","https://openalex.org/W2955141036","https://openalex.org/W2983877650","https://openalex.org/W2990053821","https://openalex.org/W3000870501","https://openalex.org/W3002051394","https://openalex.org/W3009535750","https://openalex.org/W3013462789","https://openalex.org/W3014321973","https://openalex.org/W3022907945","https://openalex.org/W3038013852","https://openalex.org/W3048417086","https://openalex.org/W3140854437","https://openalex.org/W3174273655","https://openalex.org/W6729240646"],"related_works":["https://openalex.org/W112583468","https://openalex.org/W96119380","https://openalex.org/W4298030740","https://openalex.org/W3023706879","https://openalex.org/W4246773350","https://openalex.org/W2096326357","https://openalex.org/W2108949684","https://openalex.org/W1965976436","https://openalex.org/W2012655824","https://openalex.org/W3177170977"],"abstract_inverted_index":{"Machine":[0],"learning":[1,79],"approaches":[2],"are":[3,66],"powerful":[4],"techniques":[5],"commonly":[6],"employed":[7,32],"for":[8,50,111],"developing":[9],"cancer":[10,28,38,70,81,84,86,103,142],"prediction":[11,104],"models":[12,105],"using":[13],"associated":[14,67,80],"gene":[15,33,117,132],"expression":[16,34,118,133],"and":[17,48,55,93,106,122,143],"mutation":[18],"data.":[19,95],"This":[20],"manuscript":[21],"provides":[22],"a":[23],"comprehensive":[24],"review":[25],"of":[26,62,77,89,116,141,147],"recent":[27],"studies":[29,64],"that":[30,65],"have":[31],"data":[35],"from":[36],"several":[37],"types":[39],"(breast,":[40],"lung,":[41],"kidney,":[42],"ovarian,":[43],"liver,":[44],"central":[45],"nervous":[46],"system":[47],"gallbladder)":[49],"survival":[51],"prediction,":[52,87],"tumor":[53],"identification":[54,88],"stratification.":[56],"We":[57,96],"also":[58],"provide":[59],"an":[60],"overview":[61],"biomarker":[63,90,131],"with":[68,101],"these":[69],"types.":[71],"The":[72],"survey":[73],"captures":[74],"multiple":[75],"aspects":[76],"machine":[78],"studies,":[82],"including":[83],"classification,":[85],"genes,":[91],"microarray,":[92],"RNA-Seq":[94],"discuss":[97],"the":[98,107,113,145],"technical":[99],"issues":[100],"current":[102],"corresponding":[108],"measurement":[109],"tools":[110],"determining":[112],"activity":[114],"levels":[115],"between":[119],"cancerous":[120],"tissues":[121],"noncancerous":[123],"tissues.":[124],"Additionally,":[125],"we":[126],"investigate":[127],"how":[128],"identifying":[129],"putative":[130],"patterns":[134],"can":[135],"aid":[136],"in":[137],"predicting":[138],"future":[139],"risk":[140],"inform":[144],"provision":[146],"personalized":[148],"treatment.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":43},{"year":2024,"cited_by_count":23},{"year":2023,"cited_by_count":20},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}
