{"id":"https://openalex.org/W3016579572","doi":"https://doi.org/10.1109/access.2020.2986833","title":"Stochastic Simulation of Cellular Metabolism","display_name":"Stochastic Simulation of Cellular Metabolism","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3016579572","doi":"https://doi.org/10.1109/access.2020.2986833","mag":"3016579572","pmid":"https://pubmed.ncbi.nlm.nih.gov/33747671"},"language":"en","primary_location":{"id":"doi:10.1109/access.2020.2986833","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2020.2986833","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09070186.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09070186.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026958702","display_name":"Emalie J. Clement","orcid":"https://orcid.org/0000-0002-5579-7796"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emalie J. Clement","raw_affiliation_strings":["Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA","Department of Biology, University of Nebraska at Omaha, Omaha, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I122266389"]},{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071116351","display_name":"Thomas T. Schulze","orcid":"https://orcid.org/0000-0002-3597-5727"},"institutions":[{"id":"https://openalex.org/I59130452","display_name":"University of Nebraska Medical Center","ror":"https://ror.org/00thqtb16","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I59130452"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas T. Schulze","raw_affiliation_strings":["Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA","Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, USA"],"raw_orcid":"https://orcid.org/0000-0002-3597-5727","affiliations":[{"raw_affiliation_string":"Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I59130452"]},{"raw_affiliation_string":"Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, USA","institution_ids":["https://openalex.org/I59130452"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019623840","display_name":"Ghada A. Soliman","orcid":"https://orcid.org/0000-0002-8629-6062"},"institutions":[{"id":"https://openalex.org/I174216632","display_name":"City University of New York","ror":"https://ror.org/00453a208","country_code":"US","type":"education","lineage":["https://openalex.org/I174216632"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ghada A. Soliman","raw_affiliation_strings":["Graduate School of Public Health and Health Policy, City University of New York, New York, USA","Graduate School of Public Health and Health Policy, The City University of New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Public Health and Health Policy, City University of New York, New York, USA","institution_ids":["https://openalex.org/I174216632"]},{"raw_affiliation_string":"Graduate School of Public Health and Health Policy, The City University of New York, New York, USA","institution_ids":["https://openalex.org/I174216632"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005490379","display_name":"Beata J. Wysocki","orcid":"https://orcid.org/0000-0001-9063-0126"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beata Joanna Wysocki","raw_affiliation_strings":["Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA","Department of Biology, University of Nebraska at Omaha, Omaha, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I122266389"]},{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062716929","display_name":"Paul H. Davis","orcid":"https://orcid.org/0000-0002-0526-3841"},"institutions":[{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul H. Davis","raw_affiliation_strings":["Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA","Department of Biology, University of Nebraska at Omaha, Omaha, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I122266389"]},{"raw_affiliation_string":"Department of Biology, University of Nebraska at Omaha, Omaha, USA","institution_ids":["https://openalex.org/I122266389"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068846447","display_name":"Tadeusz A. Wysocki","orcid":"https://orcid.org/0000-0001-7741-7603"},"institutions":[{"id":"https://openalex.org/I114395901","display_name":"University of Nebraska\u2013Lincoln","ror":"https://ror.org/043mer456","country_code":"US","type":"education","lineage":["https://openalex.org/I114395901"]},{"id":"https://openalex.org/I122266389","display_name":"University of Nebraska at Omaha","ror":"https://ror.org/04yrkc140","country_code":"US","type":"education","lineage":["https://openalex.org/I122266389"]},{"id":"https://openalex.org/I1300393620","display_name":"Bydgoszcz University of Science and Technology","ror":"https://ror.org/049eq0c58","country_code":"PL","type":"education","lineage":["https://openalex.org/I1300393620"]},{"id":"https://openalex.org/I4210101789","display_name":"University of Bydgoszcz","ror":"https://ror.org/01c4qa656","country_code":"PL","type":"education","lineage":["https://openalex.org/I4210101789"]}],"countries":["PL","US"],"is_corresponding":false,"raw_author_name":"Tadeusz A. Wysocki","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Nebraska - Lincoln, Omaha, Nebraska, USA","UTP University, Bydgoszcz, Poland","Department of Electrical and Computer Engineering, University of Nebraska--Lincoln, Omaha, USA","Department of Telecommunications, Computer Science and Electrical Engineering, UTP University, Bydgoszcz, Poland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Nebraska - Lincoln, Omaha, Nebraska, USA","institution_ids":["https://openalex.org/I114395901","https://openalex.org/I122266389"]},{"raw_affiliation_string":"UTP University, Bydgoszcz, Poland","institution_ids":["https://openalex.org/I1300393620","https://openalex.org/I4210101789"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Nebraska--Lincoln, Omaha, USA","institution_ids":["https://openalex.org/I114395901"]},{"raw_affiliation_string":"Department of Telecommunications, Computer Science and Electrical Engineering, UTP University, Bydgoszcz, Poland","institution_ids":["https://openalex.org/I1300393620"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.8198,"has_fulltext":true,"cited_by_count":16,"citation_normalized_percentile":{"value":0.69466623,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"8","issue":null,"first_page":"79734","last_page":"79744"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9927999973297119,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7581913471221924},{"id":"https://openalex.org/keywords/queueing-theory","display_name":"Queueing theory","score":0.6936646699905396},{"id":"https://openalex.org/keywords/stochastic-simulation","display_name":"Stochastic simulation","score":0.6038975715637207},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.4915831983089447},{"id":"https://openalex.org/keywords/modelling-biological-systems","display_name":"Modelling biological systems","score":0.46205416321754456},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.44373059272766113},{"id":"https://openalex.org/keywords/stochastic-modelling","display_name":"Stochastic modelling","score":0.42907726764678955},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.396372526884079},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.14712899923324585},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.11740201711654663}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7581913471221924},{"id":"https://openalex.org/C22684755","wikidata":"https://www.wikidata.org/wiki/Q847526","display_name":"Queueing theory","level":2,"score":0.6936646699905396},{"id":"https://openalex.org/C25915931","wikidata":"https://www.wikidata.org/wiki/Q4180825","display_name":"Stochastic simulation","level":2,"score":0.6038975715637207},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.4915831983089447},{"id":"https://openalex.org/C137866125","wikidata":"https://www.wikidata.org/wiki/Q4299308","display_name":"Modelling biological systems","level":3,"score":0.46205416321754456},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.44373059272766113},{"id":"https://openalex.org/C127491075","wikidata":"https://www.wikidata.org/wiki/Q7617825","display_name":"Stochastic modelling","level":2,"score":0.42907726764678955},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.396372526884079},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.14712899923324585},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.11740201711654663},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1109/access.2020.2986833","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2020.2986833","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09070186.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmid:33747671","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33747671","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE access : practical innovations, open solutions","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:7971159","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7971159","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access","raw_type":"Text"},{"id":"pmh:oai:digitalcommons.unl.edu:electricalengineeringfacpub-1628","is_oa":true,"landing_page_url":"https://digitalcommons.unl.edu/electricalengineeringfacpub/631","pdf_url":null,"source":{"id":"https://openalex.org/S4306400577","display_name":"Lincoln (University of Nebraska)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I114395901","host_organization_name":"University of Nebraska\u2013Lincoln","host_organization_lineage":["https://openalex.org/I114395901"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Electrical and Computer Engineering: Faculty Publications","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:47dffa829e6a4aa799f8c1937cbb959c","is_oa":true,"landing_page_url":"https://doaj.org/article/47dffa829e6a4aa799f8c1937cbb959c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 8, Pp 79734-79744 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2020.2986833","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2020.2986833","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09070186.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.46000000834465027,"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9"}],"awards":[{"id":"https://openalex.org/G4029151897","display_name":null,"funder_award_id":"P20 GM103427","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G5622482347","display_name":"A cloud-based learning module to analyze ATAC-seq and single cell ATAC-seq data","funder_award_id":"3p20gm103427-23s1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320311308","display_name":"University of Nebraska Omaha","ror":"https://ror.org/04yrkc140"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3016579572.pdf","grobid_xml":"https://content.openalex.org/works/W3016579572.grobid-xml"},"referenced_works_count":49,"referenced_works":["https://openalex.org/W51072215","https://openalex.org/W165850321","https://openalex.org/W1484811165","https://openalex.org/W1758395617","https://openalex.org/W1981106431","https://openalex.org/W1988791304","https://openalex.org/W1994628682","https://openalex.org/W2005406981","https://openalex.org/W2005454910","https://openalex.org/W2006792487","https://openalex.org/W2008163359","https://openalex.org/W2014160475","https://openalex.org/W2015840019","https://openalex.org/W2019300822","https://openalex.org/W2019692827","https://openalex.org/W2020070516","https://openalex.org/W2023089846","https://openalex.org/W2028908433","https://openalex.org/W2029110613","https://openalex.org/W2032663983","https://openalex.org/W2035151694","https://openalex.org/W2049259580","https://openalex.org/W2056865735","https://openalex.org/W2066010991","https://openalex.org/W2075416920","https://openalex.org/W2086478519","https://openalex.org/W2093470850","https://openalex.org/W2093975150","https://openalex.org/W2094015794","https://openalex.org/W2114255376","https://openalex.org/W2121777611","https://openalex.org/W2125227081","https://openalex.org/W2125997801","https://openalex.org/W2138661410","https://openalex.org/W2138672920","https://openalex.org/W2141260861","https://openalex.org/W2148499015","https://openalex.org/W2155418451","https://openalex.org/W2159482845","https://openalex.org/W2159840783","https://openalex.org/W2163184432","https://openalex.org/W2165977465","https://openalex.org/W2170697535","https://openalex.org/W2322682660","https://openalex.org/W2518463305","https://openalex.org/W2616017058","https://openalex.org/W2793943876","https://openalex.org/W4294216483","https://openalex.org/W6678672936"],"related_works":["https://openalex.org/W4386563820","https://openalex.org/W631732704","https://openalex.org/W2116778801","https://openalex.org/W2064731972","https://openalex.org/W2026456043","https://openalex.org/W2030551718","https://openalex.org/W1978131112","https://openalex.org/W3166091464","https://openalex.org/W2565468990","https://openalex.org/W2065257772"],"abstract_inverted_index":{"Increased":[0],"technological":[1],"methods":[2,19,144],"have":[3,32,50],"enabled":[4],"the":[5,15,22,42,54,58,65,79,86,94,105,112,126,138,141,150],"investigation":[6],"of":[7,17,29,44,61,67,88,107,114,128,140,155,161],"biology":[8],"at":[9],"nanoscale":[10],"levels.":[11],"Such":[12],"systems":[13,31],"require":[14],"use":[16,127],"computational":[18,95],"to":[20,56,98,117,157],"comprehend":[21],"complex":[23],"interactions":[24],"that":[25],"occur.":[26],"The":[27],"dynamics":[28],"metabolic":[30,120],"been":[33],"traditionally":[34],"described":[35],"utilizing":[36],"differential":[37],"equations":[38],"without":[39],"fully":[40],"capturing":[41],"heterogeneity":[43],"biological":[45,134],"systems.":[46,63],"Stochastic":[47],"modeling":[48,143,162],"approaches":[49],"recently":[51],"emerged":[52],"with":[53,75,122],"capacity":[55],"incorporate":[57],"statistical":[59],"properties":[60],"such":[62],"However,":[64],"processing":[66],"stochastic":[68,119],"algorithms":[69],"is":[70],"a":[71,131],"computationally":[72],"intensive":[73],"task":[74],"intrinsic":[76],"limitations.":[77],"Alternatively,":[78],"queueing":[80,115],"theory":[81,116],"approach,":[82],"historically":[83],"used":[84],"in":[85],"evaluation":[87],"telecommunication":[89],"networks,":[90],"can":[91],"significantly":[92],"reduce":[93],"power":[96,139],"required":[97],"generate":[99],"simulated":[100],"results":[101],"while":[102],"simultaneously":[103],"reducing":[104],"expansion":[106],"errors.":[108],"We":[109],"present":[110],"here":[111],"application":[113],"simulate":[118],"networks":[121],"high":[123],"efficiency.":[124],"With":[125],"glycolysis":[129,156],"as":[130],"well":[132],"understood":[133],"model,":[135],"we":[136,148],"demonstrate":[137],"proposed":[142],"discussed":[145],"herein.":[146],"Furthermore,":[147],"describe":[149],"simulation":[151],"and":[152],"pharmacological":[153],"inhibition":[154],"provide":[158],"an":[159],"example":[160],"capabilities.":[163]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1}],"updated_date":"2026-08-11T07:18:39.950985","created_date":"2025-10-10T00:00:00"}