{"id":"https://openalex.org/W3007821539","doi":"https://doi.org/10.1109/access.2020.2976797","title":"TM-ZC: A Deep Learning-Based Predictor for the Z-Coordinate of Residues in \u03b1-Helical Transmembrane Proteins","display_name":"TM-ZC: A Deep Learning-Based Predictor for the Z-Coordinate of Residues in \u03b1-Helical Transmembrane Proteins","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3007821539","doi":"https://doi.org/10.1109/access.2020.2976797","mag":"3007821539"},"language":"en","primary_location":{"id":"doi:10.1109/access.2020.2976797","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2020.2976797","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09016169.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09016169.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062138433","display_name":"Chang Lu","orcid":"https://orcid.org/0000-0001-6331-622X"},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chang Lu","raw_affiliation_strings":["School of Information Science and Technology, Northeast Normal University, Changchun, China","Institute of Computational Biology, Northeast Normal University, Changchun, China"],"raw_orcid":"https://orcid.org/0000-0001-6331-622X","affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Institute of Computational Biology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102447143","display_name":"Yingli Gong","orcid":null},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yingli Gong","raw_affiliation_strings":["School of Information Science and Technology, Northeast Normal University, Changchun, China","Institute of Computational Biology, Northeast Normal University, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Institute of Computational Biology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044574026","display_name":"Zhe Liu","orcid":"https://orcid.org/0000-0002-7685-5457"},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhe Liu","raw_affiliation_strings":["School of Information Science and Technology, Northeast Normal University, Changchun, China","Institute of Computational Biology, Northeast Normal University, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Institute of Computational Biology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077070675","display_name":"Yuanzhao Guo","orcid":null},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuanzhao Guo","raw_affiliation_strings":["School of Information Science and Technology, Northeast Normal University, Changchun, China","Institute of Computational Biology, Northeast Normal University, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Institute of Computational Biology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038788906","display_name":"Zhiqiang Ma","orcid":"https://orcid.org/0000-0002-1922-6283"},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiqiang Ma","raw_affiliation_strings":["School of Information Science and Technology, Northeast Normal University, Changchun, China","Institute of Computational Biology, Northeast Normal University, Changchun, China","Department of Computer Science, College of Humanities and Sciences, Northeast Normal University, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Institute of Computational Biology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Department of Computer Science, College of Humanities and Sciences, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100452702","display_name":"Han Wang","orcid":"https://orcid.org/0000-0002-4302-1886"},"institutions":[{"id":"https://openalex.org/I184983240","display_name":"Northeast Normal University","ror":"https://ror.org/02rkvz144","country_code":"CN","type":"education","lineage":["https://openalex.org/I184983240"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Han Wang","raw_affiliation_strings":["School of Information Science and Technology, Northeast Normal University, Changchun, China","Department of Computer Science, College of Humanities and Sciences, Northeast Normal University, Changchun, China","Institute of Computational Biology, Northeast Normal University, Changchun, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Information Science and Technology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Department of Computer Science, College of Humanities and Sciences, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]},{"raw_affiliation_string":"Institute of Computational Biology, Northeast Normal University, Changchun, China","institution_ids":["https://openalex.org/I184983240"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I184983240"],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":0.3336,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.56146687,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":97},"biblio":{"volume":"8","issue":null,"first_page":"40129","last_page":"40137"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13326","display_name":"Biochemical and Structural Characterization","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6432338356971741},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6025545597076416},{"id":"https://openalex.org/keywords/coordinate-descent","display_name":"Coordinate descent","score":0.5800101161003113},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.5110665559768677},{"id":"https://openalex.org/keywords/transmembrane-domain","display_name":"Transmembrane domain","score":0.4474923610687256},{"id":"https://openalex.org/keywords/transmembrane-protein","display_name":"Transmembrane protein","score":0.4331563413143158},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.40646690130233765},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4033201336860657},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.3794534206390381},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.16901680827140808},{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.07909265160560608}],"concepts":[{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6432338356971741},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6025545597076416},{"id":"https://openalex.org/C157553263","wikidata":"https://www.wikidata.org/wiki/Q5168004","display_name":"Coordinate descent","level":2,"score":0.5800101161003113},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.5110665559768677},{"id":"https://openalex.org/C118892022","wikidata":"https://www.wikidata.org/wiki/Q7834587","display_name":"Transmembrane domain","level":3,"score":0.4474923610687256},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.4331563413143158},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.40646690130233765},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4033201336860657},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.3794534206390381},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16901680827140808},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.07909265160560608},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/access.2020.2976797","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2020.2976797","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09016169.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:b9190cdcd15d4a6d9b92fd5f93937b56","is_oa":true,"landing_page_url":"https://doaj.org/article/b9190cdcd15d4a6d9b92fd5f93937b56","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 8, Pp 40129-40137 (2020)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2020.2976797","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2020.2976797","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8948470/09016169.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1653923516","display_name":null,"funder_award_id":"20180414006GH","funder_id":"https://openalex.org/F4320322174","funder_display_name":"People's Government of Jilin Province"},{"id":"https://openalex.org/G2309553337","display_name":null,"funder_award_id":"20170520058JH","funder_id":"https://openalex.org/F4320335953","funder_display_name":"Jilin Scientific and Technological Development Program"},{"id":"https://openalex.org/G2755366194","display_name":null,"funder_award_id":"20170520058JH","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G3254547431","display_name":null,"funder_award_id":"61802057","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G3379815116","display_name":null,"funder_award_id":"JJKH20191309KJ","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G4055583730","display_name":null,"funder_award_id":"JJKH20191309KJ","funder_id":"https://openalex.org/F4320326270","funder_display_name":"Education Department of Jilin Province"},{"id":"https://openalex.org/G4055916390","display_name":null,"funder_award_id":"JJKH20190290KJ","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G4102039166","display_name":null,"funder_award_id":"61802057","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G442978556","display_name":null,"funder_award_id":"81671328","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4560768781","display_name":null,"funder_award_id":"81671328","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G5225922884","display_name":null,"funder_award_id":"2412019FZ052","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G562891027","display_name":null,"funder_award_id":"2412019FZ048","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G6176752420","display_name":null,"funder_award_id":"20180520028JH","funder_id":"https://openalex.org/F4320322174","funder_display_name":"People's Government of Jilin Province"},{"id":"https://openalex.org/G754032093","display_name":null,"funder_award_id":"20180520028JH","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G8099088507","display_name":null,"funder_award_id":"20180414006GH","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G8598606543","display_name":null,"funder_award_id":"20180520028JH","funder_id":"https://openalex.org/F4320335953","funder_display_name":"Jilin Scientific and Technological Development Program"},{"id":"https://openalex.org/G8951103179","display_name":null,"funder_award_id":"JJKH20190290KJ","funder_id":"https://openalex.org/F4320326270","funder_display_name":"Education Department of Jilin Province"},{"id":"https://openalex.org/G961829735","display_name":null,"funder_award_id":"20180414006GH","funder_id":"https://openalex.org/F4320335953","funder_display_name":"Jilin Scientific and Technological Development Program"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322174","display_name":"People's Government of Jilin Province","ror":"https://ror.org/02fzqav45"},{"id":"https://openalex.org/F4320326270","display_name":"Education Department of Jilin Province","ror":"https://ror.org/05782e512"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null},{"id":"https://openalex.org/F4320335953","display_name":"Jilin Scientific and Technological Development Program","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3007821539.pdf","grobid_xml":"https://content.openalex.org/works/W3007821539.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1967513793","https://openalex.org/W2012604750","https://openalex.org/W2046267877","https://openalex.org/W2080638317","https://openalex.org/W2092247420","https://openalex.org/W2101934167","https://openalex.org/W2105537627","https://openalex.org/W2119872715","https://openalex.org/W2137670821","https://openalex.org/W2139754669","https://openalex.org/W2143078152","https://openalex.org/W2147580225","https://openalex.org/W2152770371","https://openalex.org/W2157380138","https://openalex.org/W2158714788","https://openalex.org/W2162274915","https://openalex.org/W2347112107","https://openalex.org/W2512408629","https://openalex.org/W2588164239","https://openalex.org/W2726111596","https://openalex.org/W2757772641","https://openalex.org/W2766300642","https://openalex.org/W2804672687","https://openalex.org/W2885051956","https://openalex.org/W2891893703","https://openalex.org/W2896636431","https://openalex.org/W2899972686","https://openalex.org/W2901879913","https://openalex.org/W2903879945","https://openalex.org/W2915518408","https://openalex.org/W2919720508","https://openalex.org/W2920118773","https://openalex.org/W2923490814","https://openalex.org/W2944389165","https://openalex.org/W2944444958","https://openalex.org/W2951569701","https://openalex.org/W2953169496","https://openalex.org/W2959696114","https://openalex.org/W2959704617","https://openalex.org/W2975224207","https://openalex.org/W2982193101","https://openalex.org/W2985559811","https://openalex.org/W2991308709","https://openalex.org/W2995722562","https://openalex.org/W2997016650","https://openalex.org/W2998225353","https://openalex.org/W3136918052"],"related_works":["https://openalex.org/W4226493464","https://openalex.org/W3099772455","https://openalex.org/W3133861977","https://openalex.org/W2129301794","https://openalex.org/W1986078734","https://openalex.org/W1540599686","https://openalex.org/W2951211570","https://openalex.org/W3103566983","https://openalex.org/W2016396528","https://openalex.org/W2261012589"],"abstract_inverted_index":{"Z-coordinate":[0],"is":[1,12,128],"an":[2,51],"important":[3],"structural":[4],"feature":[5],"of":[6,23,74,94,144,162,177],"\u03b1-helical":[7],"transmembrane":[8],"proteins":[9],"(\u03b1-TMPs),":[10],"which":[11,127],"defined":[13],"as":[14,106],"the":[15,21,24,28,42,72,76,92,100,104,137,142,151,160,175,178],"distance":[16],"from":[17,31],"a":[18,81,86,110,124,134],"residue":[19],"to":[20,53,64],"center":[22],"biological":[25],"membrane.":[26],"Since":[27],"\u03b1-TMP":[29,56],"structures":[30,57],"both":[32],"experimental":[33,118],"solved":[34],"and":[35,67,79,103,130,132,150,166,174],"computational":[36],"predicted":[37,164],"approaches":[38],"still":[39],"cannot":[40],"cover":[41],"requirements":[43],"in":[44,96],"relevant":[45],"research":[46],"fields,":[47],"z-coordinate":[48,93,165],"prediction":[49,77,145],"provides":[50],"opportunity":[52],"partly":[54],"descript":[55],"based":[58],"on":[59],"their":[60],"sequences,":[61],"further":[62,158],"contributes":[63],"function":[65],"annotation":[66],"drug":[68],"target":[69],"discovery.":[70],"For":[71],"purpose":[73],"improving":[75],"accuracy":[78],"providing":[80],"convenient":[82],"tool,":[83],"we":[84],"proposed":[85],"deep":[87],"learning-based":[88],"predictor":[89],"(TM-ZC)":[90],"for":[91,109],"residues":[95],"\u03b1-TMPs.":[97],"TM-ZC":[98,122,163],"used":[99],"one-hot":[101],"code":[102],"PSSM":[105],"input":[107],"features":[108],"convolutional":[111],"neural":[112],"network":[113],"(CNN)":[114],"regression":[115],"model.":[116],"The":[117],"results":[119],"demonstrated":[120],"that":[121],"was":[123,140,155],"powerful":[125],"predictor,":[126],"simple":[129],"fast,":[131],"achieved":[133],"considerable":[135],"performance:":[136],"average":[138],"error":[139,146],"1.958,":[141],"percent":[143],"within":[147],"3\u00c5was":[148],"77.461%,":[149],"correlation":[152],"coefficient":[153],"(CC)":[154],"0.922.":[156],"We":[157],"discussed":[159],"usefulness":[161],"found":[167],"its":[168],"high":[169],"consistency":[170],"with":[171],"topology":[172],"structure":[173],"enhancement":[176],"surface":[179],"accessibility":[180],"prediction.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3}],"updated_date":"2026-06-26T08:34:08.712188","created_date":"2020-03-06T00:00:00"}
