{"id":"https://openalex.org/W2950067894","doi":"https://doi.org/10.1109/access.2019.2922432","title":"Feature Selection for Binary Classification Within Functional Genomics Experiments via Interquartile Range and Clustering","display_name":"Feature Selection for Binary Classification Within Functional Genomics Experiments via Interquartile Range and Clustering","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2950067894","doi":"https://doi.org/10.1109/access.2019.2922432","mag":"2950067894"},"language":"en","primary_location":{"id":"doi:10.1109/access.2019.2922432","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2019.2922432","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8600701/08735703.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ieeexplore.ieee.org/ielx7/6287639/8600701/08735703.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084849204","display_name":"Zardad Khan","orcid":"https://orcid.org/0000-0003-3933-9143"},"institutions":[{"id":"https://openalex.org/I181063083","display_name":"Abdul Wali Khan University Mardan","ror":"https://ror.org/03b9y4e65","country_code":"PK","type":"education","lineage":["https://openalex.org/I181063083"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Zardad Khan","raw_affiliation_strings":["Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan"],"raw_orcid":"https://orcid.org/0000-0003-3933-9143","affiliations":[{"raw_affiliation_string":"Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan","institution_ids":["https://openalex.org/I181063083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101634953","display_name":"Muhammad Naeem","orcid":"https://orcid.org/0000-0002-8863-8767"},"institutions":[{"id":"https://openalex.org/I181063083","display_name":"Abdul Wali Khan University Mardan","ror":"https://ror.org/03b9y4e65","country_code":"PK","type":"education","lineage":["https://openalex.org/I181063083"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Muhammad Naeem","raw_affiliation_strings":["Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan","institution_ids":["https://openalex.org/I181063083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045605764","display_name":"Umair Khalil","orcid":"https://orcid.org/0000-0002-0484-5348"},"institutions":[{"id":"https://openalex.org/I181063083","display_name":"Abdul Wali Khan University Mardan","ror":"https://ror.org/03b9y4e65","country_code":"PK","type":"education","lineage":["https://openalex.org/I181063083"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Umair Khalil","raw_affiliation_strings":["Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan","institution_ids":["https://openalex.org/I181063083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003729078","display_name":"Dost Muhammad Khan","orcid":"https://orcid.org/0000-0002-3919-8136"},"institutions":[{"id":"https://openalex.org/I181063083","display_name":"Abdul Wali Khan University Mardan","ror":"https://ror.org/03b9y4e65","country_code":"PK","type":"education","lineage":["https://openalex.org/I181063083"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Dost Muhammad Khan","raw_affiliation_strings":["Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan","institution_ids":["https://openalex.org/I181063083"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021883892","display_name":"Saeed Aldahmani","orcid":"https://orcid.org/0000-0002-0826-4540"},"institutions":[{"id":"https://openalex.org/I201726411","display_name":"United Arab Emirates University","ror":"https://ror.org/01km6p862","country_code":"AE","type":"education","lineage":["https://openalex.org/I201726411"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Saeed Aldahmani","raw_affiliation_strings":["Department of Statistics, United Arab Emirates University, UAE"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, United Arab Emirates University, UAE","institution_ids":["https://openalex.org/I201726411"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029272884","display_name":"Muhammad Hamraz","orcid":null},"institutions":[{"id":"https://openalex.org/I181063083","display_name":"Abdul Wali Khan University Mardan","ror":"https://ror.org/03b9y4e65","country_code":"PK","type":"education","lineage":["https://openalex.org/I181063083"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Muhammad Hamraz","raw_affiliation_strings":["Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Statistics, Abdul Wali Khan University, Mardan, Pakistan","institution_ids":["https://openalex.org/I181063083"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":1850,"currency":"USD","value_usd":1850},"apc_paid":{"value":1850,"currency":"USD","value_usd":1850},"fwci":1.7097,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.84767351,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"7","issue":null,"first_page":"78159","last_page":"78169"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10057","display_name":"Face and Expression Recognition","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11975","display_name":"Evolutionary Algorithms and Applications","score":0.9805999994277954,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.7327098846435547},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.7311303615570068},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6893323659896851},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6803518533706665},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.6151639223098755},{"id":"https://openalex.org/keywords/random-forest","display_name":"Random forest","score":0.584082841873169},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5306272506713867},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.5225669741630554},{"id":"https://openalex.org/keywords/binary-classification","display_name":"Binary classification","score":0.5165530443191528},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.5034005045890808},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4988107681274414},{"id":"https://openalex.org/keywords/dimensionality-reduction","display_name":"Dimensionality reduction","score":0.4900108873844147},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4245692491531372},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3203180134296417},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10699048638343811}],"concepts":[{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.7327098846435547},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.7311303615570068},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6893323659896851},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6803518533706665},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.6151639223098755},{"id":"https://openalex.org/C169258074","wikidata":"https://www.wikidata.org/wiki/Q245748","display_name":"Random forest","level":2,"score":0.584082841873169},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5306272506713867},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.5225669741630554},{"id":"https://openalex.org/C66905080","wikidata":"https://www.wikidata.org/wiki/Q17005494","display_name":"Binary classification","level":3,"score":0.5165530443191528},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5034005045890808},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4988107681274414},{"id":"https://openalex.org/C70518039","wikidata":"https://www.wikidata.org/wiki/Q16000077","display_name":"Dimensionality reduction","level":2,"score":0.4900108873844147},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4245692491531372},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3203180134296417},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10699048638343811},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/access.2019.2922432","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2019.2922432","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8600701/08735703.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:5821149e45d048db896f4157596538b5","is_oa":true,"landing_page_url":"https://doaj.org/article/5821149e45d048db896f4157596538b5","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"IEEE Access, Vol 7, Pp 78159-78169 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1109/access.2019.2922432","is_oa":true,"landing_page_url":"https://doi.org/10.1109/access.2019.2922432","pdf_url":"https://ieeexplore.ieee.org/ielx7/6287639/8600701/08735703.pdf","source":{"id":"https://openalex.org/S2485537415","display_name":"IEEE Access","issn_l":"2169-3536","issn":["2169-3536"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Access","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/10","score":0.7300000190734863,"display_name":"Reduced inequalities"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2950067894.pdf","grobid_xml":"https://content.openalex.org/works/W2950067894.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W273955616","https://openalex.org/W1495216736","https://openalex.org/W1520795727","https://openalex.org/W1520812622","https://openalex.org/W1548741966","https://openalex.org/W1651173558","https://openalex.org/W1972978214","https://openalex.org/W2007028835","https://openalex.org/W2016837883","https://openalex.org/W2019683663","https://openalex.org/W2021733365","https://openalex.org/W2022892346","https://openalex.org/W2039310579","https://openalex.org/W2048178552","https://openalex.org/W2054418063","https://openalex.org/W2087684630","https://openalex.org/W2089326006","https://openalex.org/W2090091537","https://openalex.org/W2091947792","https://openalex.org/W2094023061","https://openalex.org/W2097557760","https://openalex.org/W2109363337","https://openalex.org/W2111162011","https://openalex.org/W2114060717","https://openalex.org/W2116459725","https://openalex.org/W2118249480","https://openalex.org/W2119387367","https://openalex.org/W2128985829","https://openalex.org/W2130365699","https://openalex.org/W2134837462","https://openalex.org/W2135046866","https://openalex.org/W2139151957","https://openalex.org/W2154053567","https://openalex.org/W2157963336","https://openalex.org/W2290042459","https://openalex.org/W2559504560","https://openalex.org/W2609731728","https://openalex.org/W2610135452","https://openalex.org/W2613310014","https://openalex.org/W2785412558","https://openalex.org/W2897069984","https://openalex.org/W2899235613","https://openalex.org/W2911964244","https://openalex.org/W2963799407","https://openalex.org/W4239510810","https://openalex.org/W4297957988","https://openalex.org/W4382677476","https://openalex.org/W6610017368","https://openalex.org/W6629568470","https://openalex.org/W6676974665"],"related_works":["https://openalex.org/W2965546495","https://openalex.org/W2120164251","https://openalex.org/W4388745254","https://openalex.org/W2980082554","https://openalex.org/W1517228774","https://openalex.org/W2767419625","https://openalex.org/W2389704471","https://openalex.org/W20047544","https://openalex.org/W3011239835","https://openalex.org/W4200234001"],"abstract_inverted_index":{"Datasets":[0],"produced":[1],"in":[2,19,108,130,163,220],"modern":[3],"research,":[4],"such":[5],"as":[6,69],"biomedical":[7],"science,":[8],"pose":[9],"a":[10,70,81,96,125,140],"number":[11,51,117,142],"of":[12,30,40,52,76,84,118,143,169,232],"challenges":[13],"for":[14,37,89],"machine":[15,62],"learning":[16,58,63],"techniques":[17,35,44],"used":[18,36],"binary":[20],"classification":[21,212],"due":[22],"to":[23,47,54,79,120],"high":[24],"dimensionality.":[25],"Feature":[26],"selection":[27,66,72,98,181],"is":[28,67,78,100,173,188],"one":[29],"the":[31,41,61,74,85,90,104,115,131,148,155,164,170,221,227,233,243,247],"most":[32,86,105,149],"important":[33],"statistical":[34],"dimensionality":[38],"reduction":[39],"datasets.":[42,186],"Therefore,":[43],"are":[45,128,137,152,236],"needed":[46],"find":[48,80],"an":[49],"optimal":[50],"features":[53,88],"obtain":[55],"more":[56],"desirable":[57],"performance.":[59],"In":[60,93],"context,":[64],"gene":[65,97,184],"treated":[68],"feature":[71,180],"problem,":[73],"objective":[75],"which":[77],"small":[82],"subset":[83],"discriminative":[87,106],"target":[91],"class.":[92],"this":[94],"paper,":[95],"method":[99,157,172,245],"proposed":[101,171,244],"that":[102,112,242],"identifies":[103],"genes":[107,136,151,161,205,235],"two":[109,192],"stages.":[110],"Genes":[111],"unambiguously":[113],"assign":[114],"maximum":[116],"samples":[119,208,219],"their":[121,211],"respective":[122],"classes":[123],"using":[124,183],"greedy":[126],"approach":[127],"selected":[129,153,162,204,234],"first":[132,165],"stage.":[133,166],"The":[134,167,239],"remaining":[135],"divided":[138],"into":[139],"certain":[141],"clusters.":[144],"From":[145],"each":[146],"cluster,":[147],"informative":[150],"via":[154],"lasso":[156],"and":[158,197,206,209,215,229],"combined":[159],"with":[160,177,203],"performance":[168],"assessed":[174],"through":[175],"comparison":[176],"other":[178,248],"state-of-the-art":[179],"methods":[182],"expression":[185],"This":[187],"done":[189],"by":[190],"applying":[191],"classifiers":[193],"i.e.,":[194],"random":[195],"forest":[196],"support":[198],"vector":[199],"machine,":[200],"on":[201,218,226],"datasets":[202],"training":[207],"calculating":[210],"accuracy,":[213],"sensitivity,":[214],"Brier":[216],"score":[217],"testing":[222],"part.":[223],"Boxplots":[224],"based":[225],"results":[228,240],"correlation":[230],"matrices":[231],"thenceforth":[237],"constructed.":[238],"show":[241],"outperforms":[246],"methods.":[249]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}