{"id":"https://openalex.org/W1753030380","doi":"https://doi.org/10.1109/acc.2015.7171812","title":"Bounding the effect of retroactivity in the presence of parameter uncertainty","display_name":"Bounding the effect of retroactivity in the presence of parameter uncertainty","publication_year":2015,"publication_date":"2015-07-01","ids":{"openalex":"https://openalex.org/W1753030380","doi":"https://doi.org/10.1109/acc.2015.7171812","mag":"1753030380"},"language":"en","primary_location":{"id":"doi:10.1109/acc.2015.7171812","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2015.7171812","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 American Control Conference (ACC)","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001799379","display_name":"Thomas P. Prescott","orcid":"https://orcid.org/0000-0002-9884-3887"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Thomas P. Prescott","raw_affiliation_strings":["Department of Engineering Science, University of Oxford, Oxford, UK","Department of Engineering Science University of Oxford Parks Road OX1 3PJ, UK"],"affiliations":[{"raw_affiliation_string":"Department of Engineering Science, University of Oxford, Oxford, UK","institution_ids":["https://openalex.org/I40120149"]},{"raw_affiliation_string":"Department of Engineering Science University of Oxford Parks Road OX1 3PJ, UK","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002692025","display_name":"Andr\u00e1s Gy\u00f6rgy","orcid":"https://orcid.org/0000-0001-8103-260X"},"institutions":[{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andras Gyorgy","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA","Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge 02139, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge 02139, USA","institution_ids":["https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5001799379"],"corresponding_institution_ids":["https://openalex.org/I40120149"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.02818552,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"7","issue":null,"first_page":"3120","last_page":"3125"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9977999925613403,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bounding-overwatch","display_name":"Bounding overwatch","score":0.8266435265541077},{"id":"https://openalex.org/keywords/upper-and-lower-bounds","display_name":"Upper and lower bounds","score":0.7199475765228271},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5156618356704712},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.5006270408630371},{"id":"https://openalex.org/keywords/mathematical-optimization","display_name":"Mathematical optimization","score":0.4577220678329468},{"id":"https://openalex.org/keywords/upstream","display_name":"Upstream (networking)","score":0.4460959732532501},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.40858209133148193},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.15895599126815796},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.1063266396522522}],"concepts":[{"id":"https://openalex.org/C63584917","wikidata":"https://www.wikidata.org/wiki/Q333286","display_name":"Bounding overwatch","level":2,"score":0.8266435265541077},{"id":"https://openalex.org/C77553402","wikidata":"https://www.wikidata.org/wiki/Q13222579","display_name":"Upper and lower bounds","level":2,"score":0.7199475765228271},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5156618356704712},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.5006270408630371},{"id":"https://openalex.org/C126255220","wikidata":"https://www.wikidata.org/wiki/Q141495","display_name":"Mathematical optimization","level":1,"score":0.4577220678329468},{"id":"https://openalex.org/C191172861","wikidata":"https://www.wikidata.org/wiki/Q7899321","display_name":"Upstream (networking)","level":2,"score":0.4460959732532501},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.40858209133148193},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.15895599126815796},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.1063266396522522},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/acc.2015.7171812","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2015.7171812","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 American Control Conference (ACC)","raw_type":"proceedings-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.711.332","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.711.332","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://sysos.eng.ox.ac.uk/wiki/images/3/32/Prescott2015_ACC.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W645921674","https://openalex.org/W1496537269","https://openalex.org/W1967635084","https://openalex.org/W1976865287","https://openalex.org/W1985161570","https://openalex.org/W2003847712","https://openalex.org/W2037857799","https://openalex.org/W2037913229","https://openalex.org/W2041985017","https://openalex.org/W2046713738","https://openalex.org/W2057001025","https://openalex.org/W2060603511","https://openalex.org/W2067983528","https://openalex.org/W2071990853","https://openalex.org/W2117136688","https://openalex.org/W2132724170","https://openalex.org/W2133404041","https://openalex.org/W2134800568","https://openalex.org/W2136969641","https://openalex.org/W2165372860","https://openalex.org/W2166499263","https://openalex.org/W2316378629","https://openalex.org/W6621114293","https://openalex.org/W6679392325"],"related_works":["https://openalex.org/W2132137594","https://openalex.org/W2069783012","https://openalex.org/W2085967955","https://openalex.org/W4256335355","https://openalex.org/W3098612666","https://openalex.org/W2138867060","https://openalex.org/W1499116563","https://openalex.org/W2023859141","https://openalex.org/W2182290077","https://openalex.org/W3207033120"],"abstract_inverted_index":{"As":[0],"the":[1,8,47,84,97,100,110,113],"number":[2],"of":[3,10,22,53,65,80,112],"synthetic":[4],"genetic":[5],"modules":[6],"grows,":[7],"issue":[9],"reliably":[11],"predicting":[12],"their":[13],"behavior":[14],"upon":[15],"interconnection":[16],"becomes":[17],"more":[18],"pressing.":[19],"The":[20],"trajectory":[21],"an":[23,43],"upstream":[24],"module":[25,32],"changes":[26],"once":[27],"connected":[28],"to":[29,34,41,86,105],"a":[30,63],"downstream":[31],"due":[33],"retroactivity.":[35],"Here,":[36],"we":[37,61,71],"employ":[38],"dissipativity":[39],"analysis":[40],"provide":[42],"upper":[44,59,94],"bound":[45,60],"on":[46,96],"L":[48],"<sub":[49],"xmlns:mml=\"http://www.w3.org/1998/Math/MathML\"":[50],"xmlns:xlink=\"http://www.w3.org/1999/xlink\">2</sub>":[51],"measure":[52],"this":[54,58,81],"difference.":[55],"To":[56],"obtain":[57],"formulate":[62],"Sum":[64],"Squares":[66],"(SOS)":[67],"optimization":[68],"problem":[69],"which":[70],"then":[72],"solve":[73],"using":[74],"semi-definite":[75],"programming.":[76],"One":[77],"particular":[78],"strength":[79],"approach":[82],"is":[83],"ability":[85],"successfully":[87],"handle":[88],"parameter":[89],"uncertainties":[90],"while":[91],"providing":[92],"guaranteed":[93],"bounds":[95],"difference":[98],"between":[99],"trajectories.":[101],"We":[102],"illustrate":[103],"how":[104],"apply":[106],"our":[107],"method":[108],"in":[109,117],"case":[111],"most":[114],"recurrent":[115],"motif":[116],"gene":[118],"networks.":[119]},"counts_by_year":[],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}