{"id":"https://openalex.org/W2027745826","doi":"https://doi.org/10.1109/acc.2014.6858714","title":"Uncertainty quantification for a model of HIV-1 patient response to antiretroviral therapy interruptions","display_name":"Uncertainty quantification for a model of HIV-1 patient response to antiretroviral therapy interruptions","publication_year":2014,"publication_date":"2014-06-01","ids":{"openalex":"https://openalex.org/W2027745826","doi":"https://doi.org/10.1109/acc.2014.6858714","mag":"2027745826"},"language":"en","primary_location":{"id":"doi:10.1109/acc.2014.6858714","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2014.6858714","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 American Control Conference","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031467909","display_name":"Robert Baraldi","orcid":"https://orcid.org/0000-0003-3699-6770"},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert Baraldi","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068241160","display_name":"Karissa L. Cross","orcid":"https://orcid.org/0000-0001-5618-7642"},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karissa Cross","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052200206","display_name":"Christina McChesney","orcid":null},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christina McChesney","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042927741","display_name":"Laura Poag","orcid":null},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Poag","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086759396","display_name":"Emma Thorpe","orcid":"https://orcid.org/0009-0008-8485-6418"},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emma Thorpe","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051715449","display_name":"Kevin Flores","orcid":"https://orcid.org/0000-0002-4000-6971"},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin B. Flores","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111989562","display_name":"H. T. Banks","orcid":null},"institutions":[{"id":"https://openalex.org/I137902535","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06","country_code":"US","type":"education","lineage":["https://openalex.org/I137902535"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H.T. Banks","raw_affiliation_strings":["North Carolina State University, Raleigh, NC, US","[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"North Carolina State University, Raleigh, NC, US","institution_ids":["https://openalex.org/I137902535"]},{"raw_affiliation_string":"[Center for Res. in Sci. Comput., North Carolina State Univ., Raleigh, NC, USA]","institution_ids":["https://openalex.org/I137902535"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5031467909"],"corresponding_institution_ids":["https://openalex.org/I137902535"],"apc_list":null,"apc_paid":null,"fwci":0.4587,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.61430767,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"2753","last_page":"2758"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.9872000217437744,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9538000226020813,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bootstrapping","display_name":"Bootstrapping (finance)","score":0.8071494102478027},{"id":"https://openalex.org/keywords/confidence-interval","display_name":"Confidence interval","score":0.6264007091522217},{"id":"https://openalex.org/keywords/antiretroviral-therapy","display_name":"Antiretroviral therapy","score":0.6188557744026184},{"id":"https://openalex.org/keywords/residual","display_name":"Residual","score":0.6127318143844604},{"id":"https://openalex.org/keywords/human-immunodeficiency-virus","display_name":"Human immunodeficiency virus (HIV)","score":0.5806918144226074},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.511076807975769},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.5075143575668335},{"id":"https://openalex.org/keywords/statistical-model","display_name":"Statistical model","score":0.4628234803676605},{"id":"https://openalex.org/keywords/data-modeling","display_name":"Data modeling","score":0.4181172251701355},{"id":"https://openalex.org/keywords/econometrics","display_name":"Econometrics","score":0.33632874488830566},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.33046823740005493},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2509608268737793},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.24878042936325073},{"id":"https://openalex.org/keywords/viral-load","display_name":"Viral load","score":0.22163060307502747},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.19522956013679504},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.10110163688659668}],"concepts":[{"id":"https://openalex.org/C207609745","wikidata":"https://www.wikidata.org/wiki/Q4944086","display_name":"Bootstrapping (finance)","level":2,"score":0.8071494102478027},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6264007091522217},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.6188557744026184},{"id":"https://openalex.org/C155512373","wikidata":"https://www.wikidata.org/wiki/Q287450","display_name":"Residual","level":2,"score":0.6127318143844604},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5806918144226074},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.511076807975769},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5075143575668335},{"id":"https://openalex.org/C114289077","wikidata":"https://www.wikidata.org/wiki/Q3284399","display_name":"Statistical model","level":2,"score":0.4628234803676605},{"id":"https://openalex.org/C67186912","wikidata":"https://www.wikidata.org/wiki/Q367664","display_name":"Data modeling","level":2,"score":0.4181172251701355},{"id":"https://openalex.org/C149782125","wikidata":"https://www.wikidata.org/wiki/Q160039","display_name":"Econometrics","level":1,"score":0.33632874488830566},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.33046823740005493},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2509608268737793},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24878042936325073},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.22163060307502747},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.19522956013679504},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.10110163688659668},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/acc.2014.6858714","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2014.6858714","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2014 American Control Conference","raw_type":"proceedings-article"},{"id":"pmh:oai:repository.lib.ncsu.edu:1840.4/8574","is_oa":false,"landing_page_url":"http://www.lib.ncsu.edu/resolver/1840.4/8574","pdf_url":null,"source":{"id":"https://openalex.org/S4306402468","display_name":"NCSU Libraries Repository (North Carolina State University Libraries)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I137902535","host_organization_name":"North Carolina State University","host_organization_lineage":["https://openalex.org/I137902535"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Technical report"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.699999988079071,"display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320310013","display_name":"North Carolina State University","ror":"https://ror.org/04tj63d06"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1580765587","https://openalex.org/W1964622370","https://openalex.org/W1983714443","https://openalex.org/W1984695416","https://openalex.org/W2002652672","https://openalex.org/W2029444376","https://openalex.org/W2033192330","https://openalex.org/W2068046103","https://openalex.org/W2085384576","https://openalex.org/W2113060429","https://openalex.org/W2117785982","https://openalex.org/W2120571619","https://openalex.org/W2122455852","https://openalex.org/W2131624932","https://openalex.org/W2162246041","https://openalex.org/W2171273743","https://openalex.org/W2172042588","https://openalex.org/W2172187744","https://openalex.org/W2409599807","https://openalex.org/W2480226133","https://openalex.org/W4237038146","https://openalex.org/W6714291106"],"related_works":["https://openalex.org/W1534274833","https://openalex.org/W3117246195","https://openalex.org/W156620619","https://openalex.org/W2098233217","https://openalex.org/W2914363205","https://openalex.org/W2616249226","https://openalex.org/W2997844990","https://openalex.org/W1598221548","https://openalex.org/W2073891040","https://openalex.org/W1510133244"],"abstract_inverted_index":{"We":[0,19,40],"consider":[1,42],"a":[2],"model":[3,23],"for":[4,68,79],"in-host":[5],"HIV-1":[6,36],"infection":[7],"dynamics":[8],"developed":[9],"and":[10,49,84],"validated":[11],"with":[12,52],"patient":[13],"data":[14,48],"in":[15,24,33,38,55,89],"earlier":[16,22],"work":[17],"[1].":[18],"revisit":[20],"the":[21,29,47,65,69,80,90],"light":[25],"of":[26,35,64,87],"progress":[27],"over":[28],"last":[30],"several":[31],"years":[32],"understanding":[34],"progression":[37],"humans.":[39],"then":[41,73],"statistical":[43],"models":[44],"to":[45,60,75],"describe":[46],"use":[50],"these":[51],"residual":[53],"plots":[54],"weighted":[56],"least":[57],"squares":[58],"problems":[59],"develop":[61,76],"accurate":[62],"descriptions":[63],"proper":[66],"weights":[67],"data.":[70],"Bootstrapping":[71],"is":[72],"used":[74],"confidence":[77],"intervals":[78],"resulting":[81],"parameter":[82],"estimates":[83],"establish":[85],"absence":[86],"correlation":[88],"estimated":[91],"parameters.":[92]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-05-05T08:41:31.759640","created_date":"2025-10-10T00:00:00"}