{"id":"https://openalex.org/W2100818016","doi":"https://doi.org/10.1109/acc.2013.6580543","title":"Sensitivity analysis in Petri net representation of biological systems","display_name":"Sensitivity analysis in Petri net representation of biological systems","publication_year":2013,"publication_date":"2013-06-01","ids":{"openalex":"https://openalex.org/W2100818016","doi":"https://doi.org/10.1109/acc.2013.6580543","mag":"2100818016"},"language":"en","primary_location":{"id":"doi:10.1109/acc.2013.6580543","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2013.6580543","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 American Control Conference","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027608239","display_name":"Shauheen Zahirazami","orcid":null},"institutions":[{"id":"https://openalex.org/I60158472","display_name":"Concordia University","ror":"https://ror.org/0420zvk78","country_code":"CA","type":"education","lineage":["https://openalex.org/I60158472"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Shauheen Zahirazami","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Concordia University, Montreal, QUE, Canada","Dept. of Electr. & Comput. Eng., Concordia Univ., Montre\u0301al, QC, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Concordia University, Montreal, QUE, Canada","institution_ids":["https://openalex.org/I60158472"]},{"raw_affiliation_string":"Dept. of Electr. & Comput. Eng., Concordia Univ., Montre\u0301al, QC, Canada","institution_ids":["https://openalex.org/I60158472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051732001","display_name":"Mahsa Dadar","orcid":"https://orcid.org/0000-0003-4008-2672"},"institutions":[{"id":"https://openalex.org/I60158472","display_name":"Concordia University","ror":"https://ror.org/0420zvk78","country_code":"CA","type":"education","lineage":["https://openalex.org/I60158472"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mahsa Dadar","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Concordia University, Montreal, QUE, Canada","Dept. of Electr. & Comput. Eng., Concordia Univ., Montre\u0301al, QC, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Concordia University, Montreal, QUE, Canada","institution_ids":["https://openalex.org/I60158472"]},{"raw_affiliation_string":"Dept. of Electr. & Comput. Eng., Concordia Univ., Montre\u0301al, QC, Canada","institution_ids":["https://openalex.org/I60158472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012162626","display_name":"Shahin Hashtrudi-Zad","orcid":null},"institutions":[{"id":"https://openalex.org/I60158472","display_name":"Concordia University","ror":"https://ror.org/0420zvk78","country_code":"CA","type":"education","lineage":["https://openalex.org/I60158472"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Shahin Hashtrudi-Zad","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Concordia University, Montreal, QUE, Canada","Dept. of Electr. & Comput. Eng., Concordia Univ., Montre\u0301al, QC, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Concordia University, Montreal, QUE, Canada","institution_ids":["https://openalex.org/I60158472"]},{"raw_affiliation_string":"Dept. of Electr. & Comput. Eng., Concordia Univ., Montre\u0301al, QC, Canada","institution_ids":["https://openalex.org/I60158472"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5027608239"],"corresponding_institution_ids":["https://openalex.org/I60158472"],"apc_list":null,"apc_paid":null,"fwci":0.1462,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.56749533,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"1","issue":null,"first_page":"4569","last_page":"4574"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9728999733924866,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/petri-net","display_name":"Petri net","score":0.7477489113807678},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7047444581985474},{"id":"https://openalex.org/keywords/sensitivity","display_name":"Sensitivity (control systems)","score":0.6919502019882202},{"id":"https://openalex.org/keywords/cascade","display_name":"Cascade","score":0.5489516854286194},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5227059125900269},{"id":"https://openalex.org/keywords/measure","display_name":"Measure (data warehouse)","score":0.5134554505348206},{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.4236105680465698},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.2881595194339752},{"id":"https://openalex.org/keywords/distributed-computing","display_name":"Distributed computing","score":0.2699998915195465},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2126205563545227},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.20872938632965088},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10061913728713989},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.09663453698158264}],"concepts":[{"id":"https://openalex.org/C38677869","wikidata":"https://www.wikidata.org/wiki/Q724168","display_name":"Petri net","level":2,"score":0.7477489113807678},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7047444581985474},{"id":"https://openalex.org/C21200559","wikidata":"https://www.wikidata.org/wiki/Q7451068","display_name":"Sensitivity (control systems)","level":2,"score":0.6919502019882202},{"id":"https://openalex.org/C34146451","wikidata":"https://www.wikidata.org/wiki/Q5048094","display_name":"Cascade","level":2,"score":0.5489516854286194},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5227059125900269},{"id":"https://openalex.org/C2780009758","wikidata":"https://www.wikidata.org/wiki/Q6804172","display_name":"Measure (data warehouse)","level":2,"score":0.5134554505348206},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.4236105680465698},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2881595194339752},{"id":"https://openalex.org/C120314980","wikidata":"https://www.wikidata.org/wiki/Q180634","display_name":"Distributed computing","level":1,"score":0.2699998915195465},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2126205563545227},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.20872938632965088},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10061913728713989},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.09663453698158264},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C94625758","wikidata":"https://www.wikidata.org/wiki/Q7163","display_name":"Politics","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/acc.2013.6580543","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2013.6580543","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 American Control Conference","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7799999713897705}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W12256183","https://openalex.org/W619670566","https://openalex.org/W1482637285","https://openalex.org/W1494856442","https://openalex.org/W1540436551","https://openalex.org/W1563476066","https://openalex.org/W1969551552","https://openalex.org/W1978486653","https://openalex.org/W1989121972","https://openalex.org/W1996109622","https://openalex.org/W2007625252","https://openalex.org/W2047571097","https://openalex.org/W2052853635","https://openalex.org/W2056489198","https://openalex.org/W2066534603","https://openalex.org/W2092003989","https://openalex.org/W2100486049","https://openalex.org/W2101011890","https://openalex.org/W2116789630","https://openalex.org/W2134923619","https://openalex.org/W2165637297","https://openalex.org/W2167490100","https://openalex.org/W2752061190","https://openalex.org/W2752853835","https://openalex.org/W4236305991","https://openalex.org/W6629007308"],"related_works":["https://openalex.org/W2153719181","https://openalex.org/W1971748923","https://openalex.org/W1566155057","https://openalex.org/W2060986072","https://openalex.org/W1551257573","https://openalex.org/W4230983483","https://openalex.org/W2132799268","https://openalex.org/W1980200158","https://openalex.org/W2154794415","https://openalex.org/W791317142"],"abstract_inverted_index":{"Research":[0],"in":[1,15,29,59,101],"proteomics":[2],"has":[3],"opened":[4],"a":[5],"new":[6],"door":[7],"to":[8,44],"applications":[9],"of":[10,35,38,51,63,73,80],"engineering":[11],"tools":[12],"and":[13,20,26,33,49],"techniques":[14],"biology.":[16],"Particularly":[17],"modelling":[18],"systems":[19],"control":[21],"design":[22,99],"are":[23],"becoming":[24],"more":[25,27],"important":[28],"drug":[30,98],"discovery,":[31],"diagnosis":[32],"prognosis":[34],"diseases.":[36],"Some":[37],"the":[39,46,90,94],"biggest":[40],"challenges":[41],"however":[42],"remain":[43],"be":[45],"unprecedented":[47],"size":[48],"complexity":[50],"biological":[52,64],"systems.":[53,65],"This":[54],"paper":[55],"studies":[56],"sensitivity":[57],"analysis":[58],"Petri":[60],"net":[61],"models":[62],"A":[66],"theory":[67],"is":[68,84],"developed":[69],"for":[70,97],"efficient":[71],"calculation":[72],"an":[74,78],"impotency":[75],"measure":[76,91],"as":[77],"indication":[79],"inverse":[81],"sensitivity.":[82],"It":[83],"also":[85],"shown":[86],"using":[87],"simulation":[88],"that":[89],"accurately":[92],"identifies":[93],"best":[95],"candidate":[96],"target":[100],"Caspase":[102],"cascade.":[103]},"counts_by_year":[{"year":2016,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}