{"id":"https://openalex.org/W2085606555","doi":"https://doi.org/10.1109/acc.2013.6580089","title":"Observer-based closed-loop control for the glucose-insulin system: Local Input-to-State Stability with respect to unknown meal disturbances","display_name":"Observer-based closed-loop control for the glucose-insulin system: Local Input-to-State Stability with respect to unknown meal disturbances","publication_year":2013,"publication_date":"2013-06-01","ids":{"openalex":"https://openalex.org/W2085606555","doi":"https://doi.org/10.1109/acc.2013.6580089","mag":"2085606555"},"language":"en","primary_location":{"id":"doi:10.1109/acc.2013.6580089","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2013.6580089","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 American Control Conference","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069495460","display_name":"Pasquale Palumbo","orcid":"https://orcid.org/0000-0002-9371-2802"},"institutions":[{"id":"https://openalex.org/I4210162062","display_name":"Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti","ror":"https://ror.org/054ye0e45","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210155236","https://openalex.org/I4210162062"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"P. Palumbo","raw_affiliation_strings":["Istituto di Analisi dei Sistemi e Informatica, Italian National Research Research Council, Viale Manzoni, Roma, Italy","Ist. di Analisi dei Sist. e Inf., Italian Nat. Res. Res. Council, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Istituto di Analisi dei Sistemi e Informatica, Italian National Research Research Council, Viale Manzoni, Roma, Italy","institution_ids":["https://openalex.org/I4210162062"]},{"raw_affiliation_string":"Ist. di Analisi dei Sist. e Inf., Italian Nat. Res. Res. Council, Rome, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051832041","display_name":"Pierdomenico Pepe","orcid":"https://orcid.org/0000-0001-8522-1643"},"institutions":[{"id":"https://openalex.org/I26415053","display_name":"University of L'Aquila","ror":"https://ror.org/01j9p1r26","country_code":"IT","type":"education","lineage":["https://openalex.org/I26415053"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"P. Pepe","raw_affiliation_strings":["Universita degli Studi dell'Aquila, L'Aquila, Abruzzo, IT","Dept. of Electr. & Inf. Eng., Univ. of L'Aquila, Poggio di Roio, Italy"],"affiliations":[{"raw_affiliation_string":"Universita degli Studi dell'Aquila, L'Aquila, Abruzzo, IT","institution_ids":["https://openalex.org/I26415053"]},{"raw_affiliation_string":"Dept. of Electr. & Inf. Eng., Univ. of L'Aquila, Poggio di Roio, Italy","institution_ids":["https://openalex.org/I26415053"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090279484","display_name":"Simona Panunzi","orcid":"https://orcid.org/0000-0003-0956-8578"},"institutions":[{"id":"https://openalex.org/I4210162062","display_name":"Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti","ror":"https://ror.org/054ye0e45","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210155236","https://openalex.org/I4210162062"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"S. Panunzi","raw_affiliation_strings":["Istituto di Analisi dei Sistemi e Informatica, Italian National Research Research Council, Viale Manzoni, Roma, Italy","Ist. di Analisi dei Sist. e Inf., Italian Nat. Res. Res. Council, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Istituto di Analisi dei Sistemi e Informatica, Italian National Research Research Council, Viale Manzoni, Roma, Italy","institution_ids":["https://openalex.org/I4210162062"]},{"raw_affiliation_string":"Ist. di Analisi dei Sist. e Inf., Italian Nat. Res. Res. Council, Rome, Italy","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073738479","display_name":"Andrea De Gaetano","orcid":"https://orcid.org/0000-0001-7712-056X"},"institutions":[{"id":"https://openalex.org/I4210162062","display_name":"Istituto di Analisi dei Sistemi ed Informatica Antonio Ruberti","ror":"https://ror.org/054ye0e45","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210155236","https://openalex.org/I4210162062"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"A. De Gaetano","raw_affiliation_strings":["Istituto di Analisi dei Sistemi e Informatica, Italian National Research Research Council, Viale Manzoni, Roma, Italy","Ist. di Analisi dei Sist. e Inf., Italian Nat. Res. Res. Council, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Istituto di Analisi dei Sistemi e Informatica, Italian National Research Research Council, Viale Manzoni, Roma, Italy","institution_ids":["https://openalex.org/I4210162062"]},{"raw_affiliation_string":"Ist. di Analisi dei Sist. e Inf., Italian Nat. Res. Res. Council, Rome, Italy","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5069495460"],"corresponding_institution_ids":["https://openalex.org/I4210162062"],"apc_list":null,"apc_paid":null,"fwci":0.9634,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.77635707,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"1751","last_page":"1756"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.9919000267982483,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.76368248462677},{"id":"https://openalex.org/keywords/insulin","display_name":"Insulin","score":0.6389142274856567},{"id":"https://openalex.org/keywords/stability","display_name":"Stability (learning theory)","score":0.5333547592163086},{"id":"https://openalex.org/keywords/exponential-stability","display_name":"Exponential stability","score":0.5313587188720703},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.5092209577560425},{"id":"https://openalex.org/keywords/meal","display_name":"Meal","score":0.5052779316902161},{"id":"https://openalex.org/keywords/equivalence","display_name":"Equivalence (formal languages)","score":0.46956944465637207},{"id":"https://openalex.org/keywords/feed-forward","display_name":"Feed forward","score":0.4333551526069641},{"id":"https://openalex.org/keywords/controller","display_name":"Controller (irrigation)","score":0.4271320700645447},{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.40910738706588745},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.31511449813842773},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.24623340368270874},{"id":"https://openalex.org/keywords/endocrinology","display_name":"Endocrinology","score":0.20058351755142212},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.17021146416664124},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.15253934264183044},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.13803356885910034},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.13781234622001648},{"id":"https://openalex.org/keywords/control-engineering","display_name":"Control engineering","score":0.10568982362747192},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09569144248962402},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.0762416422367096}],"concepts":[{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.76368248462677},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.6389142274856567},{"id":"https://openalex.org/C112972136","wikidata":"https://www.wikidata.org/wiki/Q7595718","display_name":"Stability (learning theory)","level":2,"score":0.5333547592163086},{"id":"https://openalex.org/C167964875","wikidata":"https://www.wikidata.org/wiki/Q17011487","display_name":"Exponential stability","level":3,"score":0.5313587188720703},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.5092209577560425},{"id":"https://openalex.org/C2778345441","wikidata":"https://www.wikidata.org/wiki/Q6460735","display_name":"Meal","level":2,"score":0.5052779316902161},{"id":"https://openalex.org/C2780069185","wikidata":"https://www.wikidata.org/wiki/Q7977945","display_name":"Equivalence (formal languages)","level":2,"score":0.46956944465637207},{"id":"https://openalex.org/C38858127","wikidata":"https://www.wikidata.org/wiki/Q5441228","display_name":"Feed forward","level":2,"score":0.4333551526069641},{"id":"https://openalex.org/C203479927","wikidata":"https://www.wikidata.org/wiki/Q5165939","display_name":"Controller (irrigation)","level":2,"score":0.4271320700645447},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.40910738706588745},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.31511449813842773},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.24623340368270874},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.20058351755142212},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.17021146416664124},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15253934264183044},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.13803356885910034},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.13781234622001648},{"id":"https://openalex.org/C133731056","wikidata":"https://www.wikidata.org/wiki/Q4917288","display_name":"Control engineering","level":1,"score":0.10568982362747192},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09569144248962402},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0762416422367096},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1109/acc.2013.6580089","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2013.6580089","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2013 American Control Conference","raw_type":"proceedings-article"},{"id":"pmh:oai:boa.unimib.it:10281/246699","is_oa":false,"landing_page_url":"http://hdl.handle.net/10281/246699","pdf_url":null,"source":{"id":"https://openalex.org/S4306401259","display_name":"BOA (University of Milano-Bicocca)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I66752286","host_organization_name":"University of Milano-Bicocca","host_organization_lineage":["https://openalex.org/I66752286"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W626483778","https://openalex.org/W1964693647","https://openalex.org/W1967020823","https://openalex.org/W1982267787","https://openalex.org/W1982830050","https://openalex.org/W1998796882","https://openalex.org/W2001875222","https://openalex.org/W2017493230","https://openalex.org/W2025709654","https://openalex.org/W2027342926","https://openalex.org/W2029679825","https://openalex.org/W2047017331","https://openalex.org/W2068270626","https://openalex.org/W2076787612","https://openalex.org/W2099719924","https://openalex.org/W2114735269","https://openalex.org/W2125624587","https://openalex.org/W2126592113","https://openalex.org/W2134323508","https://openalex.org/W2142962347","https://openalex.org/W2144614463","https://openalex.org/W2146639180","https://openalex.org/W2151316409","https://openalex.org/W2151848469","https://openalex.org/W2154952552","https://openalex.org/W2162957926","https://openalex.org/W2170849807","https://openalex.org/W2171270340","https://openalex.org/W2171394095","https://openalex.org/W2319929992","https://openalex.org/W2325390432","https://openalex.org/W2745328403","https://openalex.org/W4211202937","https://openalex.org/W4247416913","https://openalex.org/W6678663635"],"related_works":["https://openalex.org/W2286391053","https://openalex.org/W2982600058","https://openalex.org/W1963486701","https://openalex.org/W2312483540","https://openalex.org/W4249477090","https://openalex.org/W191745111","https://openalex.org/W1522083559","https://openalex.org/W2007570603","https://openalex.org/W2808224918","https://openalex.org/W2773679836"],"abstract_inverted_index":{"Closed-loop":[0],"glucose":[1,18,126],"control":[2,48,118],"schemes,":[3],"usually":[4],"based":[5,52],"on":[6,53],"intravenous/subcutaneous":[7],"insulin":[8],"administration,":[9],"need":[10],"to":[11,26,93,122],"cope":[12],"with":[13,67,91,120],"the":[14,34,40,54,64,68,81,85,94,114,117,135],"problem":[15],"of":[16,36,39,56,63,116],"exogenous":[17],"intake":[19],"(e.g.":[20],"a":[21,23,57,73,123,131],"meal),":[22],"disturbance":[24],"hard":[25],"anticipate":[27],"in":[28,30,33],"timing,":[29],"amount":[31],"and":[32,102],"rate":[35,128],"effective":[37],"absorption":[38],"nutrient.":[41],"In":[42],"this":[43],"note,":[44],"an":[45],"intravenous":[46],"feedback":[47],"law":[49],"is":[50,78,110],"considered,":[51],"use":[55],"Delay":[58],"Differential":[59],"Equation":[60],"(DDE)":[61],"model":[62],"glucose-insulin":[65],"system,":[66],"external":[69],"meal":[70],"treated":[71],"as":[72],"completely":[74],"unknown":[75,95],"disturbance.":[76,96],"It":[77],"shown":[79],"that":[80],"closed-loop":[82],"system":[83],"satisfies":[84],"local":[86,103],"Input-to-State":[87],"Stability":[88],"(ISS)":[89],"property":[90],"respect":[92,121],"The":[97],"equivalence":[98],"between":[99],"asymptotic":[100],"stability":[101,105],"input-to-state":[104],"for":[106],"retarded":[107],"nonlinear":[108],"systems":[109],"proven.":[111],"Simulations":[112],"show":[113],"efficacy":[115],"algorithm":[119],"standard":[124],"plasma":[125],"appearance":[127],"profile":[129],"following":[130],"meal,":[132],"taken":[133],"from":[134],"literature.":[136]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}