{"id":"https://openalex.org/W2045205787","doi":"https://doi.org/10.1109/acc.2012.6314690","title":"Identification of nucleation rates in droplet-based microfluidic systems","display_name":"Identification of nucleation rates in droplet-based microfluidic systems","publication_year":2012,"publication_date":"2012-06-01","ids":{"openalex":"https://openalex.org/W2045205787","doi":"https://doi.org/10.1109/acc.2012.6314690","mag":"2045205787"},"language":"en","primary_location":{"id":"doi:10.1109/acc.2012.6314690","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2012.6314690","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 American Control Conference (ACC)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000134787","display_name":"K. Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K. Chen","raw_affiliation_strings":["Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031971329","display_name":"Li May Goh","orcid":null},"institutions":[{"id":"https://openalex.org/I1332737386","display_name":"General Electric (United States)","ror":"https://ror.org/013msgt25","country_code":"US","type":"company","lineage":["https://openalex.org/I1332737386"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L. Goh","raw_affiliation_strings":["Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","General Electric Water & Process Technologies, GE SWTC, 1 Engineering Drive 1, Singapore 117580"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"General Electric Water & Process Technologies, GE SWTC, 1 Engineering Drive 1, Singapore 117580","institution_ids":["https://openalex.org/I1332737386"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112304415","display_name":"Guangwen He","orcid":null},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I74680897","display_name":"Procter & Gamble (United States)","ror":"https://ror.org/04dkns738","country_code":"US","type":"company","lineage":["https://openalex.org/I74680897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Guangwen He","raw_affiliation_strings":["Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","Procter and Gamble, Japan K.K., 17 Koyo-cho Naka 1-chome, Higashinada-ku, Kobe 658-0032, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Procter and Gamble, Japan K.K., 17 Koyo-cho Naka 1-chome, Higashinada-ku, Kobe 658-0032, Japan","institution_ids":["https://openalex.org/I74680897"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057868460","display_name":"Paul J. A. Kenis","orcid":"https://orcid.org/0000-0001-7348-0381"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. J. A. Kenis","raw_affiliation_strings":["Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091173043","display_name":"Charles F. Zukoski","orcid":"https://orcid.org/0009-0003-4885-7505"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. F. Zukoski","raw_affiliation_strings":["Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083684552","display_name":"Richard D. Braatz","orcid":"https://orcid.org/0000-0003-4304-3484"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. D. Braatz","raw_affiliation_strings":["Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical & Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"University of Illinois at Urbana-Champaign, 600 South Matthews Avenue, Urbana, IL 61801","institution_ids":["https://openalex.org/I157725225"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18835731,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"196","issue":null,"first_page":"863","last_page":"868"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11881","display_name":"Crystallization and Solubility Studies","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11881","display_name":"Crystallization and Solubility Studies","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10864","display_name":"Fluid Dynamics and Mixing","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleation","display_name":"Nucleation","score":0.946914553642273},{"id":"https://openalex.org/keywords/supersaturation","display_name":"Supersaturation","score":0.8186255693435669},{"id":"https://openalex.org/keywords/classical-nucleation-theory","display_name":"Classical nucleation theory","score":0.6396178007125854},{"id":"https://openalex.org/keywords/microfluidics","display_name":"Microfluidics","score":0.48651188611984253},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.41831421852111816},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.40355056524276733},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.38808274269104004},{"id":"https://openalex.org/keywords/chemical-physics","display_name":"Chemical physics","score":0.3503451943397522},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.3250671923160553},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.21473675966262817}],"concepts":[{"id":"https://openalex.org/C61048295","wikidata":"https://www.wikidata.org/wiki/Q909022","display_name":"Nucleation","level":2,"score":0.946914553642273},{"id":"https://openalex.org/C200447597","wikidata":"https://www.wikidata.org/wiki/Q334104","display_name":"Supersaturation","level":2,"score":0.8186255693435669},{"id":"https://openalex.org/C2780393986","wikidata":"https://www.wikidata.org/wiki/Q19892223","display_name":"Classical nucleation theory","level":3,"score":0.6396178007125854},{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.48651188611984253},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.41831421852111816},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.40355056524276733},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.38808274269104004},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.3503451943397522},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.3250671923160553},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.21473675966262817}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/acc.2012.6314690","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2012.6314690","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2012 American Control Conference (ACC)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.44999998807907104,"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W623363057","https://openalex.org/W1484646597","https://openalex.org/W1513339763","https://openalex.org/W1539859753","https://openalex.org/W1964386634","https://openalex.org/W1967068504","https://openalex.org/W1967193064","https://openalex.org/W1973438039","https://openalex.org/W1986315702","https://openalex.org/W1994722349","https://openalex.org/W1996776705","https://openalex.org/W2010668049","https://openalex.org/W2017306698","https://openalex.org/W2020068704","https://openalex.org/W2020438216","https://openalex.org/W2027457134","https://openalex.org/W2028946253","https://openalex.org/W2034694310","https://openalex.org/W2036358259","https://openalex.org/W2036694628","https://openalex.org/W2042418195","https://openalex.org/W2046507078","https://openalex.org/W2048719859","https://openalex.org/W2055389014","https://openalex.org/W2056571685","https://openalex.org/W2058184924","https://openalex.org/W2059632291","https://openalex.org/W2059770951","https://openalex.org/W2077908415","https://openalex.org/W2089167182","https://openalex.org/W2098254896","https://openalex.org/W2099071486","https://openalex.org/W2118642938","https://openalex.org/W2139148856","https://openalex.org/W2140640071","https://openalex.org/W2148314255","https://openalex.org/W2150514371","https://openalex.org/W2155430461","https://openalex.org/W2225923242","https://openalex.org/W2316088916","https://openalex.org/W2318480578","https://openalex.org/W2319118409","https://openalex.org/W2609724571","https://openalex.org/W2979255838","https://openalex.org/W3026026050","https://openalex.org/W3147825576","https://openalex.org/W3214760094","https://openalex.org/W4210448011","https://openalex.org/W4213379039","https://openalex.org/W4232265961"],"related_works":["https://openalex.org/W2141887464","https://openalex.org/W1970728619","https://openalex.org/W2020772873","https://openalex.org/W2088149062","https://openalex.org/W2349968082","https://openalex.org/W1970448750","https://openalex.org/W2002658200","https://openalex.org/W2090795069","https://openalex.org/W4390236584","https://openalex.org/W2537249726"],"abstract_inverted_index":{"Characterization":[0],"of":[1,4,6,13,69,102,155,191,204],"the":[2,28,63,80,99,103,131,135,140,153,167,189,202],"rate":[3,65,133],"nucleation":[5,40,64,81,108,132,154,169,177,193],"crystals":[7,159],"from":[8,134],"solution":[9,101],"continues":[10],"to":[11,124,185],"be":[12,183],"interest,":[14],"both":[15],"for":[16,25,59,79,107,147,152,188,196,201],"investigations":[17],"into":[18,113],"fundamental":[19],"molecular":[20],"phenomena":[21],"as":[22,24,66,163,212],"well":[23],"applications":[26],"in":[27,41,96,160,165],"pharmaceuticals,":[29],"biotechnology,":[30],"and":[31,115,127,157,195,214],"fine":[32],"chemicals":[33],"industries.":[34],"Substantial":[35],"experimental":[36,136],"evidence":[37],"indicates":[38],"that":[39,71,91,109,120,206],"some":[42],"solute-solvent":[43],"systems":[44],"does":[45,72],"not":[46,73],"agree":[47],"with":[48,175],"classical":[49,176],"theory,":[50,178],"especially":[51],"at":[52,208],"high":[53,209],"supersaturations.":[54],"An":[55],"approach":[56,84,144,181],"is":[57,145],"proposed":[58],"computing":[60],"bounds":[61,129],"on":[62,130],"a":[67,87,117],"function":[68],"supersaturation":[70],"require":[74],"an":[75],"assumed":[76],"analytical":[77,100],"expression":[78],"kinetics.":[82],"The":[83,143,180],"involves":[85],"(1)":[86],"high-throughput":[88],"microfluidic":[89,141],"platform":[90],"measures":[92],"crystal":[93],"nuclei":[94],"formation":[95],"droplets,":[97],"(2)":[98],"Chemical":[104],"Master":[105],"equation":[106],"takes":[110],"finite-volume":[111],"effects":[112],"account,":[114],"(3)":[116],"numerical":[118],"algorithm":[119],"employs":[121],"linear":[122],"splines":[123],"construct":[125],"upper":[126],"lower":[128],"data":[137],"produced":[138],"by":[139],"platform.":[142],"demonstrated":[146],"mean":[148],"induction":[149],"times":[150],"measured":[151,168],"paracetamol":[156],"glycine":[158],"aqueous":[161],"solution,":[162],"examples":[164],"which":[166],"kinetics":[170],"are":[171],"consistent":[172],"or":[173],"inconsistent":[174],"respectively.":[179],"can":[182],"used":[184],"suggest":[186],"dependencies":[187],"development":[190],"new":[192],"expressions":[194],"providing":[197],"kinetic":[198],"information":[199],"needed":[200],"simulation":[203],"crystallizers":[205],"operate":[207],"supersaturations,":[210],"such":[211],"dual-impinging-jet":[213],"vortex-mixer":[215],"crystallizers.":[216]},"counts_by_year":[],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}