{"id":"https://openalex.org/W2037615879","doi":"https://doi.org/10.1109/acc.2006.1655438","title":"A mathematic model of a cardiovascular system regulated by the baroreflex","display_name":"A mathematic model of a cardiovascular system regulated by the baroreflex","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W2037615879","doi":"https://doi.org/10.1109/acc.2006.1655438","mag":"2037615879"},"language":"en","primary_location":{"id":"doi:10.1109/acc.2006.1655438","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2006.1655438","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2006 American Control Conference","raw_type":"proceedings-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103787802","display_name":"Shaohui Chen","orcid":"https://orcid.org/0000-0001-7999-6338"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shaohui Chen","raw_affiliation_strings":["Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044024183","display_name":"Ant\u00f3nio Ferreira","orcid":"https://orcid.org/0000-0002-5809-2126"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Ferreira","raw_affiliation_strings":["Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061897875","display_name":"Marwan A. Simaan","orcid":"https://orcid.org/0000-0002-5393-2018"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M.A. Simaan","raw_affiliation_strings":["Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048217378","display_name":"James F. Antaki","orcid":"https://orcid.org/0000-0002-5430-7353"},"institutions":[{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.F. Antaki","raw_affiliation_strings":["Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I74973139"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5103787802"],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":null,"apc_paid":null,"fwci":0.3904,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.66958255,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"73","issue":null,"first_page":"6 pp.","last_page":"6 pp."},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11196","display_name":"Non-Invasive Vital Sign Monitoring","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9900000095367432,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/baroreflex","display_name":"Baroreflex","score":0.8567809462547302},{"id":"https://openalex.org/keywords/preload","display_name":"Preload","score":0.8476696014404297},{"id":"https://openalex.org/keywords/afterload","display_name":"Afterload","score":0.6752516031265259},{"id":"https://openalex.org/keywords/ventricle","display_name":"Ventricle","score":0.532446026802063},{"id":"https://openalex.org/keywords/heart-rate","display_name":"Heart rate","score":0.5225845575332642},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"Hemodynamics","score":0.5219045281410217},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"Blood pressure","score":0.47416701912879944},{"id":"https://openalex.org/keywords/contractility","display_name":"Contractility","score":0.46402648091316223},{"id":"https://openalex.org/keywords/nonlinear-system","display_name":"Nonlinear system","score":0.4483345150947571},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.448040634393692},{"id":"https://openalex.org/keywords/control-theory","display_name":"Control theory (sociology)","score":0.4475546181201935},{"id":"https://openalex.org/keywords/circulatory-system","display_name":"Circulatory system","score":0.43012818694114685},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.38052108883857727},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.35030004382133484},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.33120888471603394},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.22483602166175842},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.20917072892189026}],"concepts":[{"id":"https://openalex.org/C191237925","wikidata":"https://www.wikidata.org/wiki/Q808725","display_name":"Baroreflex","level":4,"score":0.8567809462547302},{"id":"https://openalex.org/C48277249","wikidata":"https://www.wikidata.org/wiki/Q1406926","display_name":"Preload","level":3,"score":0.8476696014404297},{"id":"https://openalex.org/C123576724","wikidata":"https://www.wikidata.org/wiki/Q1299082","display_name":"Afterload","level":3,"score":0.6752516031265259},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.532446026802063},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.5225845575332642},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.5219045281410217},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.47416701912879944},{"id":"https://openalex.org/C39133596","wikidata":"https://www.wikidata.org/wiki/Q5165683","display_name":"Contractility","level":2,"score":0.46402648091316223},{"id":"https://openalex.org/C158622935","wikidata":"https://www.wikidata.org/wiki/Q660848","display_name":"Nonlinear system","level":2,"score":0.4483345150947571},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.448040634393692},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.4475546181201935},{"id":"https://openalex.org/C72859922","wikidata":"https://www.wikidata.org/wiki/Q11068","display_name":"Circulatory system","level":2,"score":0.43012818694114685},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38052108883857727},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.35030004382133484},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33120888471603394},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.22483602166175842},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.20917072892189026},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/acc.2006.1655438","is_oa":false,"landing_page_url":"https://doi.org/10.1109/acc.2006.1655438","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2006 American Control Conference","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8500000238418579}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1848462296","https://openalex.org/W1986772524","https://openalex.org/W2034222148","https://openalex.org/W2270805275","https://openalex.org/W2284443087"],"related_works":["https://openalex.org/W148300690","https://openalex.org/W1946513951","https://openalex.org/W2013556385","https://openalex.org/W2067890185","https://openalex.org/W2069907911","https://openalex.org/W2078520321","https://openalex.org/W3005312026","https://openalex.org/W2566751840","https://openalex.org/W2071098679","https://openalex.org/W191471520"],"abstract_inverted_index":{"A":[0],"dynamic,":[1],"nonlinear,":[2],"lumped":[3],"parameter":[4],"model":[5,14,22,95,119,158],"of":[6,24,106,144,152,161],"the":[7,21,25,52,61,70,75,107,139,157,176],"cardiovascular":[8,18,111],"system":[9,19,72,114],"coupled":[10,100],"with":[11,169],"a":[12,36,66],"baroreflex":[13,44,94,113],"is":[15,33,45,56,96,130,159],"presented.":[16],"The":[17,43,93,104,150],"in":[20,51,69,118,121,138,175],"consists":[23],"left":[26,124],"heart":[27,80,83,128],"(ventricle)":[28],"and":[29,32,59,85,112,127],"systemic":[30,76],"load":[31],"represented":[34,97],"by":[35,73,98,134],"fourth":[37],"order":[38,110],"nonlinear":[39,101],"time-varying":[40],"differential":[41,102],"equation.":[42],"an":[46],"important":[47],"internal":[48],"feedback":[49],"mechanism":[50],"body":[53],"whose":[54],"function":[55],"to":[57,115],"regulate":[58],"stabilize":[60],"blood":[62,87],"pressure.":[63,92],"It":[64],"plays":[65],"major":[67],"role":[68],"circulatory":[71],"adjusting":[74],"vascular":[77],"resistance":[78],"(SVR),":[79],"rate":[81,129],"(HR),":[82],"contractility":[84],"total":[86],"volume":[88],"based":[89],"on":[90],"arterial":[91],"seven":[99],"equations.":[103],"response":[105],"combined":[108,140],"eleventh":[109],"single":[116],"changes":[117],"parameters":[120,137],"preload,":[122],"afterload,":[123],"ventricular":[125],"contractility,":[126],"examined.":[131],"More":[132],"specifically,":[133],"changing":[135],"certain":[136],"model,":[141],"different":[142],"levels":[143],"human":[145,164],"activities":[146],"can":[147],"be":[148],"simulated.":[149],"results":[151],"our":[153],"studies":[154],"show":[155],"that":[156],"capable":[160],"reproducing":[162],"coherent":[163],"hemodynamic":[165],"responses":[166],"which":[167],"agree":[168],"real":[170],"exercise":[171],"experimental":[172],"data":[173],"reported":[174],"literature.":[177]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}