{"id":"https://openalex.org/W2063599581","doi":"https://doi.org/10.1109/35021bigcomp.2015.7072853","title":"Analysis of DFNA5's three distinct mutations by Apriori, decision tree","display_name":"Analysis of DFNA5's three distinct mutations by Apriori, decision tree","publication_year":2015,"publication_date":"2015-02-01","ids":{"openalex":"https://openalex.org/W2063599581","doi":"https://doi.org/10.1109/35021bigcomp.2015.7072853","mag":"2063599581"},"language":"en","primary_location":{"id":"doi:10.1109/35021bigcomp.2015.7072853","is_oa":false,"landing_page_url":"https://doi.org/10.1109/35021bigcomp.2015.7072853","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 International Conference on Big Data and Smart Computing (BIGCOMP)","raw_type":"proceedings-article"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101785106","display_name":"Kyoungmin Kim","orcid":"https://orcid.org/0000-0001-5063-0869"},"institutions":[{"id":"https://openalex.org/I83436808","display_name":"Hankuk University of Foreign Studies","ror":"https://ror.org/051q2m369","country_code":"KR","type":"education","lineage":["https://openalex.org/I83436808"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyoungmin Kim","raw_affiliation_strings":["Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea","institution_ids":["https://openalex.org/I83436808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102257412","display_name":"Jae-Hoon Sung","orcid":null},"institutions":[{"id":"https://openalex.org/I83436808","display_name":"Hankuk University of Foreign Studies","ror":"https://ror.org/051q2m369","country_code":"KR","type":"education","lineage":["https://openalex.org/I83436808"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jaehoon Sung","raw_affiliation_strings":["Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea","institution_ids":["https://openalex.org/I83436808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047245735","display_name":"Seokyoon Chang","orcid":null},"institutions":[{"id":"https://openalex.org/I83436808","display_name":"Hankuk University of Foreign Studies","ror":"https://ror.org/051q2m369","country_code":"KR","type":"education","lineage":["https://openalex.org/I83436808"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Seokyoon Chang","raw_affiliation_strings":["Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea","institution_ids":["https://openalex.org/I83436808"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109263098","display_name":"Taeseon Yoon","orcid":null},"institutions":[{"id":"https://openalex.org/I83436808","display_name":"Hankuk University of Foreign Studies","ror":"https://ror.org/051q2m369","country_code":"KR","type":"education","lineage":["https://openalex.org/I83436808"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Taeseon Yoon","raw_affiliation_strings":["Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of International, Hankuk Academy of Foreign Studies (HAFS), Yongin, South Korea","institution_ids":["https://openalex.org/I83436808"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I83436808"],"apc_list":null,"apc_paid":null,"fwci":1.1769,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.79420889,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":"9","issue":null,"first_page":"63","last_page":"66"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9824000000953674,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10334","display_name":"Hearing, Cochlea, Tinnitus, Genetics","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.6139076352119446},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.5593450665473938},{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.5483496785163879},{"id":"https://openalex.org/keywords/homo-sapiens","display_name":"Homo sapiens","score":0.5417575836181641},{"id":"https://openalex.org/keywords/glycine","display_name":"Glycine","score":0.47895294427871704},{"id":"https://openalex.org/keywords/alanine","display_name":"Alanine","score":0.4725078046321869},{"id":"https://openalex.org/keywords/a-priori-and-a-posteriori","display_name":"A priori and a posteriori","score":0.4321483373641968},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4072265923023224},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3786691129207611},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3579527735710144},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3310413956642151},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.23798295855522156},{"id":"https://openalex.org/keywords/sociology","display_name":"Sociology","score":0.06568270921707153}],"concepts":[{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.6139076352119446},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.5593450665473938},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5483496785163879},{"id":"https://openalex.org/C2777938546","wikidata":"https://www.wikidata.org/wiki/Q5","display_name":"Homo sapiens","level":2,"score":0.5417575836181641},{"id":"https://openalex.org/C2777756961","wikidata":"https://www.wikidata.org/wiki/Q620730","display_name":"Glycine","level":3,"score":0.47895294427871704},{"id":"https://openalex.org/C2779856020","wikidata":"https://www.wikidata.org/wiki/Q218642","display_name":"Alanine","level":3,"score":0.4725078046321869},{"id":"https://openalex.org/C75553542","wikidata":"https://www.wikidata.org/wiki/Q178161","display_name":"A priori and a posteriori","level":2,"score":0.4321483373641968},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4072265923023224},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3786691129207611},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3579527735710144},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3310413956642151},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.23798295855522156},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.06568270921707153},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/35021bigcomp.2015.7072853","is_oa":false,"landing_page_url":"https://doi.org/10.1109/35021bigcomp.2015.7072853","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 International Conference on Big Data and Smart Computing (BIGCOMP)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/16","score":0.7200000286102295,"display_name":"Peace, Justice and strong institutions"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1550660916","https://openalex.org/W1986960525","https://openalex.org/W2059627714","https://openalex.org/W2122642866","https://openalex.org/W2160429448","https://openalex.org/W2160821224"],"related_works":["https://openalex.org/W2108654338","https://openalex.org/W2052955587","https://openalex.org/W2000063314","https://openalex.org/W2073794275","https://openalex.org/W4256205827","https://openalex.org/W2227647145","https://openalex.org/W2098869593","https://openalex.org/W2048736030","https://openalex.org/W2351136315","https://openalex.org/W2309489207"],"abstract_inverted_index":{"DFNA5's":[0],"mutations":[1],"are":[2,112],"known":[3],"as":[4],"the":[5,71,92,99,135],"reason":[6],"of":[7,122],"autosomal":[8],"dominant":[9],"non-syndromic":[10],"hearing":[11],"loss":[12],"(ADNSHL).":[13],"To":[14],"date,":[15],"DFNA5":[16],"has":[17],"been":[18],"mostly":[19],"experimented":[20],"by":[21,34],"particular":[22,60],"families'":[23],"DNA":[24],"samples.":[25],"By":[26],"using":[27],"three":[28],"homo":[29],"sapiens":[30],"deafness":[31],"sequences":[32,40],"provided":[33],"ncbi,":[35],"we":[36],"investigated":[37],"amino":[38,55,75,95,132],"acid":[39,56,76],"in":[41,67,81],"order":[42,68],"to":[43,52,69,79,97,105],"analyze":[44],"relationships":[45],"among":[46],"mutants.":[47],"We":[48],"used":[49],"apriori":[50],"algorithm":[51,66],"find":[53],"common":[54],"which":[57],"indicates":[58],"a":[59,85],"feature":[61],"and":[62,73,89,110,125],"decision":[63],"tree":[64],"C5.0":[65],"discover":[70],"difference":[72],"what":[74],"is":[77],"likely":[78],"appear":[80],"each":[82],"position.":[83],"As":[84],"result,":[86],"Leucine,":[87],"Glycine,":[88],"Alanine":[90],"were":[91],"most":[93],"crucial":[94],"acids":[96,133],"explain":[98],"relationship.":[100],"This":[101],"result":[102],"made":[103],"us":[104],"speculate":[106],"that":[107],"variant":[108,115],"2":[109],"3":[111],"derived":[113],"from":[114],"1.":[116],"Hereby,":[117],"our":[118],"experiment":[119],"suggests":[120],"features":[121],"these":[123,131],"mutants":[124],"arouses":[126],"further":[127],"research":[128],"about":[129],"how":[130],"affect":[134],"hearing-impaired.":[136]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-07-29T14:22:42.915294","created_date":"2025-10-10T00:00:00"}