{"id":"https://openalex.org/W2142428670","doi":"https://doi.org/10.1093/nar/gkt1226","title":"The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST)","display_name":"The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST)","publication_year":2013,"publication_date":"2013-11-29","ids":{"openalex":"https://openalex.org/W2142428670","doi":"https://doi.org/10.1093/nar/gkt1226","mag":"2142428670","pmid":"https://pubmed.ncbi.nlm.nih.gov/24293654"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkt1226","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkt1226","pdf_url":"https://academic.oup.com/nar/article-pdf/42/D1/D206/3644245/gkt1226.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/42/D1/D206/3644245/gkt1226.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085138988","display_name":"Ross Overbeek","orcid":null},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ross Overbeek","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, Computation Institute, University of Chicago, Chicago, IL 60637, USA, Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, Computation Institute, University of Chicago, Chicago, IL 60637, USA, Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":[]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015210172","display_name":"Robert Olson","orcid":"https://orcid.org/0000-0001-9751-4734"},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Olson","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066616906","display_name":"Gordon D. Pusch","orcid":"https://orcid.org/0000-0003-1471-0401"},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon D. Pusch","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109061648","display_name":"G J Olsen","orcid":null},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary J. Olsen","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023451003","display_name":"James J. Davis","orcid":"https://orcid.org/0000-0003-0104-5852"},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James J. Davis","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111684840","display_name":"Terry Disz","orcid":null},"institutions":[{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Terry Disz","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036802114","display_name":"Robert A. Edwards","orcid":"https://orcid.org/0000-0001-8383-8949"},"institutions":[{"id":"https://openalex.org/I26538001","display_name":"San Diego State University","ror":"https://ror.org/0264fdx42","country_code":"US","type":"education","lineage":["https://openalex.org/I26538001"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert A. Edwards","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","San Diego State University"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"San Diego State University","institution_ids":["https://openalex.org/I26538001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054837516","display_name":"Svetlana Gerdes","orcid":"https://orcid.org/0000-0001-5472-2912"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Svetlana Gerdes","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026370684","display_name":"Bruce Parrello","orcid":null},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce Parrello","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040025864","display_name":"Maulik Shukla","orcid":"https://orcid.org/0009-0002-3396-5725"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maulik Shukla","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","Virginia Polytechnic Institute And State University"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"Virginia Polytechnic Institute And State University","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036781580","display_name":"Veronika Vonstein","orcid":null},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Veronika Vonstein","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021998590","display_name":"Alice R. Wattam","orcid":"https://orcid.org/0000-0001-6018-6490"},"institutions":[{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alice R. Wattam","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","Virginia Polytechnic Institute And State University"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"Virginia Polytechnic Institute And State University","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049471852","display_name":"Fangfang Xia","orcid":"https://orcid.org/0000-0001-6567-0564"},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fangfang Xia","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053682943","display_name":"Rick Stevens","orcid":"https://orcid.org/0000-0002-4268-4020"},"institutions":[{"id":"https://openalex.org/I1282105669","display_name":"Argonne National Laboratory","ror":"https://ror.org/05gvnxz63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1282105669","https://openalex.org/I1330989302","https://openalex.org/I39565521","https://openalex.org/I40347166"]},{"id":"https://openalex.org/I39422238","display_name":"University of Illinois Chicago","ror":"https://ror.org/02mpq6x41","country_code":"US","type":"education","lineage":["https://openalex.org/I39422238"]},{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rick Stevens","raw_affiliation_strings":["Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","University of Illinois Urbana-Champaign, Urbana, United States"],"affiliations":[{"raw_affiliation_string":"Fellowship for Interpretation of Genomes, Burr Ridge, IL 60527, USA, 2Mathematics and Computer Science Division, Argonne National Laboratory, Argonne, IL 60439, USA, 3Computation Institute, University of Chicago, Chicago, IL 60637, USA, 4Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA, 5Department of Computer Science, San Diego State University, San Diego, CA 92182, USA, 6Virginia Bioinformatics Institute, Virginia Tech, Blacksburg, VA 24060, USA, 7Computing, Environment and Life Sciences, Argonne National Laboratory, Argonne, IL 60439, USA and 8Department of Computer Science, University of Chicago, Chicago, IL 60637, USA","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1282105669","https://openalex.org/I39422238","https://openalex.org/I40347166"]},{"raw_affiliation_string":"University of Illinois Urbana-Champaign, Urbana, United States","institution_ids":["https://openalex.org/I157725225"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5085138988"],"corresponding_institution_ids":["https://openalex.org/I157725225"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":100.3265,"has_fulltext":true,"cited_by_count":4581,"citation_normalized_percentile":{"value":0.99982778,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"42","issue":"D1","first_page":"D206","last_page":"D214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/annotation","display_name":"Annotation","score":0.8564269542694092},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.8081753253936768},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.7380122542381287},{"id":"https://openalex.org/keywords/genome-project","display_name":"Genome project","score":0.5976574420928955},{"id":"https://openalex.org/keywords/scripting-language","display_name":"Scripting language","score":0.5681366920471191},{"id":"https://openalex.org/keywords/gene-annotation","display_name":"Gene Annotation","score":0.5376509428024292},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.48755425214767456},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.43242567777633667},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.42015576362609863},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.33640390634536743},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.30277711153030396},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2927253842353821},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.1053076982498169}],"concepts":[{"id":"https://openalex.org/C2776321320","wikidata":"https://www.wikidata.org/wiki/Q857525","display_name":"Annotation","level":2,"score":0.8564269542694092},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.8081753253936768},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7380122542381287},{"id":"https://openalex.org/C89566754","wikidata":"https://www.wikidata.org/wiki/Q2273828","display_name":"Genome project","level":4,"score":0.5976574420928955},{"id":"https://openalex.org/C61423126","wikidata":"https://www.wikidata.org/wiki/Q187432","display_name":"Scripting language","level":2,"score":0.5681366920471191},{"id":"https://openalex.org/C2908923196","wikidata":"https://www.wikidata.org/wiki/Q5205742","display_name":"Gene Annotation","level":4,"score":0.5376509428024292},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.48755425214767456},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.43242567777633667},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.42015576362609863},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.33640390634536743},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.30277711153030396},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2927253842353821},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.1053076982498169}],"mesh":[{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016680","descriptor_name":"Genome, Bacterial","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020407","descriptor_name":"Internet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020745","descriptor_name":"Genome, Archaeal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020745","descriptor_name":"Genome, Archaeal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020745","descriptor_name":"Genome, Archaeal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D030541","descriptor_name":"Databases, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/nar/gkt1226","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkt1226","pdf_url":"https://academic.oup.com/nar/article-pdf/42/D1/D206/3644245/gkt1226.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:24293654","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24293654","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:osti.gov:1625520","is_oa":true,"landing_page_url":"https://www.osti.gov/biblio/1625520","pdf_url":"https://www.osti.gov/servlets/purl/1625520","source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:vtechworks.lib.vt.edu:10919/88953","is_oa":true,"landing_page_url":"http://hdl.handle.net/10919/88953","pdf_url":"http://hdl.handle.net/10919/88953","source":{"id":"https://openalex.org/S4306400248","display_name":"VTechWorks (Virginia Tech)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I859038795","host_organization_name":"Virginia Tech","host_organization_lineage":["https://openalex.org/I859038795"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:europepmc.org:2943237","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3965101","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/nar/gkt1226","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkt1226","pdf_url":"https://academic.oup.com/nar/article-pdf/42/D1/D206/3644245/gkt1226.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G848032724","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337398","display_name":"Division of Biological Infrastructure","ror":"https://ror.org/04qn9mx93"},{"id":"https://openalex.org/F4320337509","display_name":"Biological and Environmental Research","ror":"https://ror.org/0114b2m14"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2142428670.pdf","grobid_xml":"https://content.openalex.org/works/W2142428670.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W159790035","https://openalex.org/W315903372","https://openalex.org/W378747138","https://openalex.org/W634466483","https://openalex.org/W1582212884","https://openalex.org/W1587558271","https://openalex.org/W1652691445","https://openalex.org/W1971403296","https://openalex.org/W1975970608","https://openalex.org/W1982613010","https://openalex.org/W1995117714","https://openalex.org/W1998767819","https://openalex.org/W2004548026","https://openalex.org/W2020350008","https://openalex.org/W2025002407","https://openalex.org/W2030062456","https://openalex.org/W2033713984","https://openalex.org/W2077190448","https://openalex.org/W2096525273","https://openalex.org/W2097107919","https://openalex.org/W2100084634","https://openalex.org/W2105199251","https://openalex.org/W2105742081","https://openalex.org/W2108649941","https://openalex.org/W2114034054","https://openalex.org/W2134153749","https://openalex.org/W2141626941","https://openalex.org/W2143119085","https://openalex.org/W2145514756","https://openalex.org/W2155368965","https://openalex.org/W2158714788","https://openalex.org/W2162704968","https://openalex.org/W2167708455","https://openalex.org/W2170806980","https://openalex.org/W2605068739","https://openalex.org/W4212920271","https://openalex.org/W4230784961","https://openalex.org/W4239833500","https://openalex.org/W4242729757"],"related_works":["https://openalex.org/W2059565715","https://openalex.org/W1999129612","https://openalex.org/W2162782320","https://openalex.org/W2009940763","https://openalex.org/W3111061871","https://openalex.org/W1760213857","https://openalex.org/W110079389","https://openalex.org/W2099626126","https://openalex.org/W2043778888","https://openalex.org/W45826765"],"abstract_inverted_index":{"In":[0,64],"2004,":[1],"the":[2,74,93,96,120,124,134,140,156,160,183,186,191],"SEED":[3,30,75,135,187],"(http://pubseed.theseed.org/)":[4],"was":[5],"created":[6],"to":[7,66,107,119,148,155,197],"provide":[8],"consistent":[9],"and":[10,18,24,47,60,85,112,136,152,189,195],"accurate":[11],"genome":[12,41,104,125],"annotations":[13,114],"across":[14],"thousands":[15],"of":[16,36,80,95,158,164,185],"genomes":[17,177],"as":[19],"a":[20,32,40,68,102,150],"platform":[21],"for":[22,56,71],"discovering":[23,61],"developing":[25],"de":[26],"novo":[27],"annotations.":[28],"The":[29],"is":[31,51,105,126,130],"constantly":[33],"updated":[34],"integration":[35],"genomic":[37],"data":[38],"with":[39],"database,":[42],"web":[43],"front":[44],"end,":[45],"API":[46],"server":[48],"scripts.":[49],"It":[50],"used":[52],"by":[53,117],"many":[54],"scientists":[55],"predicting":[57],"gene":[58],"functions":[59],"new":[62,103],"pathways.":[63],"addition":[65],"being":[67],"powerful":[69],"database":[70,188],"bioinformatics":[72],"research,":[73],"also":[76],"houses":[77],"subsystems":[78],"(collections":[79],"functionally":[81],"related":[82],"protein":[83],"families)":[84],"their":[86,113],"derived":[87],"FIGfams":[88],"(protein":[89],"families),":[90],"which":[91],"represent":[92],"core":[94],"RAST":[97,192],"annotation":[98,144,193],"engine":[99],"(http://rast.nmpdr.org/).":[100],"When":[101],"submitted":[106],"RAST,":[108,190],"genes":[109],"are":[110,115],"called":[111],"made":[116,127],"comparison":[118],"FIGfam":[121,141],"collection.":[122,142],"If":[123],"public,":[128],"it":[129],"then":[131],"housed":[132],"within":[133],"its":[137],"proteins":[138],"populate":[139],"This":[143],"cycle":[145],"has":[146],"proven":[147],"be":[149],"robust":[151],"scalable":[153],"solution":[154],"problem":[157],"annotating":[159],"exponentially":[161],"increasing":[162],"number":[163],"genomes.":[165],"To":[166],"date,":[167],">12":[168],"000":[169,175],"users":[170],"worldwide":[171],"have":[172],"annotated":[173],">60":[174],"distinct":[176],"using":[178],"RAST.":[179],"Here":[180],"we":[181],"describe":[182],"interconnectedness":[184],"pipeline":[194],"updates":[196],"both":[198],"resources.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":98},{"year":2025,"cited_by_count":322},{"year":2024,"cited_by_count":376},{"year":2023,"cited_by_count":403},{"year":2022,"cited_by_count":468},{"year":2021,"cited_by_count":529},{"year":2020,"cited_by_count":486},{"year":2019,"cited_by_count":429},{"year":2018,"cited_by_count":382},{"year":2017,"cited_by_count":410},{"year":2016,"cited_by_count":336},{"year":2015,"cited_by_count":253},{"year":2014,"cited_by_count":80},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}