{"id":"https://openalex.org/W4307468105","doi":"https://doi.org/10.1093/nar/gkac972","title":"The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease","display_name":"The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease","publication_year":2022,"publication_date":"2022-10-28","ids":{"openalex":"https://openalex.org/W4307468105","doi":"https://doi.org/10.1093/nar/gkac972","pmid":"https://pubmed.ncbi.nlm.nih.gov/36305825"},"language":"en","primary_location":{"id":"doi:10.1093/nar/gkac972","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac972","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1038/48441590/gkac972.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1038/48441590/gkac972.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011041769","display_name":"Tudor Groza","orcid":"https://orcid.org/0000-0003-2267-8333"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Tudor Groza","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047489800","display_name":"Federico L\u00f3pez","orcid":"https://orcid.org/0000-0002-7138-3542"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Federico Lopez Gomez","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073055395","display_name":"Hamed Mashhadi","orcid":"https://orcid.org/0000-0002-0514-1617"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hamed Haseli Mashhadi","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004693476","display_name":"Violeta Mu\u00f1oz\u2010Fuentes","orcid":null},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Violeta Mu\u00f1oz-Fuentes","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033370547","display_name":"Osman G\u00fcne\u015f","orcid":"https://orcid.org/0000-0002-4987-6981"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Osman Gunes","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114378237","display_name":"Robert Wilson","orcid":"https://orcid.org/0000-0002-9407-5526"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Robert Wilson","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000691453","display_name":"Pilar Cacheiro","orcid":"https://orcid.org/0000-0002-6335-8208"},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I4210149920","display_name":"William Harvey Research Institute","ror":"https://ror.org/0574dzy90","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079","https://openalex.org/I4210149920"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Pilar Cacheiro","raw_affiliation_strings":["William Harvey Research Institute, Queen Mary University of London , London EC1M 6BQ, UK"],"affiliations":[{"raw_affiliation_string":"William Harvey Research Institute, Queen Mary University of London , London EC1M 6BQ, UK","institution_ids":["https://openalex.org/I4210149920","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008707063","display_name":"Anthony Frost","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anthony Frost","raw_affiliation_strings":["Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK"],"affiliations":[{"raw_affiliation_string":"Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024455603","display_name":"Piia Keskivali-Bond","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Piia Keskivali-Bond","raw_affiliation_strings":["Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK"],"affiliations":[{"raw_affiliation_string":"Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071572475","display_name":"Bora Vardal","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bora Vardal","raw_affiliation_strings":["Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK"],"affiliations":[{"raw_affiliation_string":"Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021749193","display_name":"Aaron McCoy","orcid":"https://orcid.org/0000-0001-6487-3546"},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Aaron McCoy","raw_affiliation_strings":["Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK"],"affiliations":[{"raw_affiliation_string":"Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004116043","display_name":"Tsz Kwan Cheng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Tsz Kwan Cheng","raw_affiliation_strings":["Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK"],"affiliations":[{"raw_affiliation_string":"Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063683507","display_name":"Lu\u00eds Santos","orcid":"https://orcid.org/0000-0001-6403-4902"},"institutions":[{"id":"https://openalex.org/I125680101","display_name":"Turing Institute","ror":"https://ror.org/02x2mw849","country_code":"GB","type":"facility","lineage":["https://openalex.org/I125680101"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Luis Santos","raw_affiliation_strings":["Research Data Team, The Turing Institute , 96 Euston Rd, London NW1 2DB, UK"],"affiliations":[{"raw_affiliation_string":"Research Data Team, The Turing Institute , 96 Euston Rd, London NW1 2DB, UK","institution_ids":["https://openalex.org/I125680101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106733432","display_name":"Sara Wells","orcid":null},"institutions":[{"id":"https://openalex.org/I4210086857","display_name":"Mary Lyon Centre at MRC Harwell","ror":"https://ror.org/0001h1y25","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210086857","https://openalex.org/I4210087105","https://openalex.org/I90344618"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sara Wells","raw_affiliation_strings":["Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK"],"affiliations":[{"raw_affiliation_string":"Mary Lyon Centre at MRC Harwell , Harwell Campus OX11 7UE, UK","institution_ids":["https://openalex.org/I4210086857"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009950897","display_name":"Damian Smedley","orcid":"https://orcid.org/0000-0002-5836-9850"},"institutions":[{"id":"https://openalex.org/I166337079","display_name":"Queen Mary University of London","ror":"https://ror.org/026zzn846","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079"]},{"id":"https://openalex.org/I4210149920","display_name":"William Harvey Research Institute","ror":"https://ror.org/0574dzy90","country_code":"GB","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I166337079","https://openalex.org/I4210149920"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Damian Smedley","raw_affiliation_strings":["William Harvey Research Institute, Queen Mary University of London , London EC1M 6BQ, UK"],"affiliations":[{"raw_affiliation_string":"William Harvey Research Institute, Queen Mary University of London , London EC1M 6BQ, UK","institution_ids":["https://openalex.org/I4210149920","https://openalex.org/I166337079"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084604490","display_name":"Ann\u2010Marie Mallon","orcid":"https://orcid.org/0000-0003-4047-4019"},"institutions":[{"id":"https://openalex.org/I125680101","display_name":"Turing Institute","ror":"https://ror.org/02x2mw849","country_code":"GB","type":"facility","lineage":["https://openalex.org/I125680101"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ann-Marie Mallon","raw_affiliation_strings":["Research Data Team, The Turing Institute , 96 Euston Rd, London NW1 2DB, UK"],"affiliations":[{"raw_affiliation_string":"Research Data Team, The Turing Institute , 96 Euston Rd, London NW1 2DB, UK","institution_ids":["https://openalex.org/I125680101"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020620537","display_name":"Helen Parkinson","orcid":"https://orcid.org/0000-0003-3035-4195"},"institutions":[{"id":"https://openalex.org/I1303153112","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1303153112","https://openalex.org/I4210138560"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Helen Parkinson","raw_affiliation_strings":["European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK"],"affiliations":[{"raw_affiliation_string":"European Bioinformatics Institute, European Molecular Biology Laboratory , Welcome Genome Campus, Hinxton\u00a0CB10 1SD, UK","institution_ids":["https://openalex.org/I1303153112"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":17,"corresponding_author_ids":["https://openalex.org/A5011041769"],"corresponding_institution_ids":["https://openalex.org/I1303153112"],"apc_list":{"value":3630,"currency":"USD","value_usd":3630},"apc_paid":{"value":3630,"currency":"USD","value_usd":3630},"fwci":36.0192,"has_fulltext":true,"cited_by_count":431,"citation_normalized_percentile":{"value":0.99898385,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"51","issue":"D1","first_page":"D1038","last_page":"D1045"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9832000136375427,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9832000136375427,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9603000283241272,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.9527000188827515,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.9135926961898804},{"id":"https://openalex.org/keywords/underpinning","display_name":"Underpinning","score":0.798947811126709},{"id":"https://openalex.org/keywords/human-disease","display_name":"Human disease","score":0.5152935981750488},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5021424293518066},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4685042202472687},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4209045469760895},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.2625318765640259},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.0952623188495636}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9135926961898804},{"id":"https://openalex.org/C2780871342","wikidata":"https://www.wikidata.org/wiki/Q7883752","display_name":"Underpinning","level":2,"score":0.798947811126709},{"id":"https://openalex.org/C2988867146","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Human disease","level":3,"score":0.5152935981750488},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5021424293518066},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4685042202472687},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4209045469760895},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2625318765640259},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0952623188495636},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C147176958","wikidata":"https://www.wikidata.org/wiki/Q77590","display_name":"Civil engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/nar/gkac972","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac972","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1038/48441590/gkac972.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},{"id":"pmid:36305825","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36305825","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic acids research","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9825559","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9825559","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nucleic Acids Res","raw_type":"Text"},{"id":"pmh:oai:qmro.qmul.ac.uk:123456789/82599","is_oa":true,"landing_page_url":"https://qmro.qmul.ac.uk/xmlui/handle/123456789/82599","pdf_url":null,"source":{"id":"https://openalex.org/S4306400530","display_name":"Queen Mary Research Online (Queen Mary University of London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I166337079","host_organization_name":"Queen Mary University of London","host_organization_lineage":["https://openalex.org/I166337079"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1093/nar/gkac972","is_oa":true,"landing_page_url":"https://doi.org/10.1093/nar/gkac972","pdf_url":"https://academic.oup.com/nar/article-pdf/51/D1/D1038/48441590/gkac972.pdf","source":{"id":"https://openalex.org/S134668137","display_name":"Nucleic Acids Research","issn_l":"0305-1048","issn":["0305-1048","1362-4954","1362-4962"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nucleic Acids Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6000000238418579,"id":"https://metadata.un.org/sdg/17","display_name":"Partnerships for the goals"}],"awards":[{"id":"https://openalex.org/G434242917","display_name":null,"funder_award_id":"2UM1HG006370-11","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8481574455","display_name":null,"funder_award_id":"MC_UP_2201/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320313288","display_name":"European Bioinformatics Institute","ror":"https://ror.org/02catss52"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4307468105.pdf","grobid_xml":"https://content.openalex.org/works/W4307468105.grobid-xml"},"referenced_works_count":45,"referenced_works":["https://openalex.org/W1966303573","https://openalex.org/W2010798628","https://openalex.org/W2028415076","https://openalex.org/W2157079123","https://openalex.org/W2214711630","https://openalex.org/W2518901523","https://openalex.org/W2558643140","https://openalex.org/W2558970413","https://openalex.org/W2577502906","https://openalex.org/W2671308999","https://openalex.org/W2705861159","https://openalex.org/W2761793335","https://openalex.org/W2782654301","https://openalex.org/W2796464660","https://openalex.org/W2804919189","https://openalex.org/W2900255713","https://openalex.org/W2901332105","https://openalex.org/W2901527454","https://openalex.org/W2904925280","https://openalex.org/W2936745823","https://openalex.org/W2945275601","https://openalex.org/W2965541130","https://openalex.org/W2979820532","https://openalex.org/W2995766518","https://openalex.org/W2998400169","https://openalex.org/W2999585943","https://openalex.org/W3003209623","https://openalex.org/W3014855304","https://openalex.org/W3036780289","https://openalex.org/W3087722312","https://openalex.org/W3093143042","https://openalex.org/W3106143834","https://openalex.org/W3115444894","https://openalex.org/W3127522569","https://openalex.org/W3144460008","https://openalex.org/W3192232080","https://openalex.org/W3200938988","https://openalex.org/W3201435727","https://openalex.org/W3204910154","https://openalex.org/W3212464243","https://openalex.org/W4200272197","https://openalex.org/W4212829112","https://openalex.org/W4212919921","https://openalex.org/W4226322299","https://openalex.org/W4380077595"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W623382837","https://openalex.org/W2155197844","https://openalex.org/W2349226017","https://openalex.org/W4327953582","https://openalex.org/W4393222579","https://openalex.org/W4296277698","https://openalex.org/W2044340941","https://openalex.org/W2322763599","https://openalex.org/W2014372623"],"abstract_inverted_index":{"The":[0,40,118],"International":[1],"Mouse":[2],"Phenotyping":[3],"Consortium":[4],"(IMPC;":[5],"https://www.mousephenotype.org/)":[6],"web":[7],"portal":[8,42],"makes":[9],"available":[10],"curated,":[11],"integrated":[12,122],"and":[13,29,56,64,88,101,109,123,139],"analysed":[14],"knockout":[15],"mouse":[16,86],"phenotyping":[17],"data":[18,27,138],"generated":[19],"by":[20,80],"the":[21,50,61,68,74,96,99,110,124,134,137,140],"IMPC":[22,41,69],"project":[23],"consisting":[24],"of":[25,52,77,98,136],"85M":[26],"points":[28],"over":[30,130],"95,000":[31],"statistically":[32],"significant":[33],"phenotype":[34],"hits":[35],"mapped":[36],"to":[37,73],"human":[38,116],"diseases.":[39,117],"delivers":[43],"a":[44],"substantial":[45],"reference":[46],"dataset":[47],"that":[48],"supports":[49],"enrichment":[51],"various":[53],"domain-specific":[54],"projects":[55],"databases,":[57],"as":[58,60],"well":[59],"wider":[62],"research":[63],"clinical":[65],"community,":[66],"where":[67],"genotype-phenotype":[70],"knowledge":[71,104],"contributes":[72],"molecular":[75],"diagnosis":[76],"patients":[78],"affected":[79],"rare":[81],"disorders.":[82],"Data":[83],"from":[84],"9,000":[85],"lines":[87,125],"750":[89],"000":[90],"images":[91],"provides":[92],"vital":[93],"resources":[94],"enabling":[95],"interpretation":[97],"ignorome,":[100],"advancing":[102],"our":[103],"on":[105],"mammalian":[106],"gene":[107],"function":[108],"mechanisms":[111],"underlying":[112],"phenotypes":[113],"associated":[114],"with":[115],"resource":[119],"is":[120],"widely":[121],"have":[126],"been":[127],"used":[128],"in":[129],"4,600":[131],"publications":[132],"indicating":[133],"value":[135],"materials.":[141]},"counts_by_year":[{"year":2026,"cited_by_count":31},{"year":2025,"cited_by_count":145},{"year":2024,"cited_by_count":154},{"year":2023,"cited_by_count":96},{"year":2022,"cited_by_count":4}],"updated_date":"2026-04-16T08:26:57.006410","created_date":"2025-10-10T00:00:00"}