{"id":"https://openalex.org/W2979920993","doi":"https://doi.org/10.1093/jamia/ocz169","title":"Using clinical reasoning ontologies to make smarter clinical decision support systems: a systematic review and data synthesis","display_name":"Using clinical reasoning ontologies to make smarter clinical decision support systems: a systematic review and data synthesis","publication_year":2019,"publication_date":"2019-09-05","ids":{"openalex":"https://openalex.org/W2979920993","doi":"https://doi.org/10.1093/jamia/ocz169","mag":"2979920993","pmid":"https://pubmed.ncbi.nlm.nih.gov/31592534"},"language":"en","primary_location":{"id":"doi:10.1093/jamia/ocz169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocz169","pdf_url":"https://academic.oup.com/jamia/article-pdf/27/1/159/34152570/ocz169.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/jamia/article-pdf/27/1/159/34152570/ocz169.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022085296","display_name":"Pavithra I. Dissanayake","orcid":"https://orcid.org/0000-0002-4306-0797"},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pavithra I Dissanayake","raw_affiliation_strings":["Informatics Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Informatics Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034186950","display_name":"Tiago K. Colicchio","orcid":"https://orcid.org/0000-0003-3405-1538"},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tiago K Colicchio","raw_affiliation_strings":["Informatics Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Informatics Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085160284","display_name":"James J. Cimino","orcid":"https://orcid.org/0000-0003-4101-1622"},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James J Cimino","raw_affiliation_strings":["Informatics Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Informatics Institute, University of Alabama at Birmingham, Birmingham, Alabama, USA","institution_ids":["https://openalex.org/I32389192"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5022085296"],"corresponding_institution_ids":["https://openalex.org/I32389192"],"apc_list":{"value":3967,"currency":"USD","value_usd":3967},"apc_paid":null,"fwci":3.333,"has_fulltext":true,"cited_by_count":96,"citation_normalized_percentile":{"value":0.93317158,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"27","issue":"1","first_page":"159","last_page":"174"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.3603000044822693,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.3603000044822693,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.23960000276565552,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.14869999885559082,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6537790894508362},{"id":"https://openalex.org/keywords/clinical-decision-support-system","display_name":"Clinical decision support system","score":0.5841405391693115},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.48545485734939575},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"Decision support system","score":0.47818782925605774},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.263241171836853}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6537790894508362},{"id":"https://openalex.org/C63527458","wikidata":"https://www.wikidata.org/wiki/Q5133829","display_name":"Clinical decision support system","level":3,"score":0.5841405391693115},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.48545485734939575},{"id":"https://openalex.org/C107327155","wikidata":"https://www.wikidata.org/wiki/Q330268","display_name":"Decision support system","level":2,"score":0.47818782925605774},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.263241171836853}],"mesh":[{"descriptor_ui":"D000086723","descriptor_name":"Clinical Reasoning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000086723","descriptor_name":"Clinical Reasoning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000086723","descriptor_name":"Clinical Reasoning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000086723","descriptor_name":"Clinical Reasoning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020000","descriptor_name":"Decision Support Systems, Clinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064229","descriptor_name":"Biological Ontologies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/jamia/ocz169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocz169","pdf_url":"https://academic.oup.com/jamia/article-pdf/27/1/159/34152570/ocz169.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},{"id":"pmid:31592534","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31592534","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association : JAMIA","raw_type":null},{"id":"pmh:oai:europepmc.org:5872683","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6913230","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/jamia/ocz169","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jamia/ocz169","pdf_url":"https://academic.oup.com/jamia/article-pdf/27/1/159/34152570/ocz169.pdf","source":{"id":"https://openalex.org/S129839026","display_name":"Journal of the American Medical Informatics Association","issn_l":"1067-5027","issn":["1067-5027","1527-974X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Medical Informatics Association","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2965848412","display_name":null,"funder_award_id":"UL1TR003096","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6856943961","display_name":null,"funder_award_id":"UL1TR003096","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2979920993.pdf","grobid_xml":"https://content.openalex.org/works/W2979920993.grobid-xml"},"referenced_works_count":94,"referenced_works":["https://openalex.org/W178654588","https://openalex.org/W194568253","https://openalex.org/W246286872","https://openalex.org/W350134141","https://openalex.org/W1489295663","https://openalex.org/W1504095063","https://openalex.org/W1523302530","https://openalex.org/W1578484316","https://openalex.org/W1579874153","https://openalex.org/W1601829769","https://openalex.org/W1782193986","https://openalex.org/W1923946131","https://openalex.org/W1963406418","https://openalex.org/W1970233990","https://openalex.org/W1979997212","https://openalex.org/W2001169684","https://openalex.org/W2001771035","https://openalex.org/W2007868748","https://openalex.org/W2009172889","https://openalex.org/W2016166457","https://openalex.org/W2025189988","https://openalex.org/W2028822295","https://openalex.org/W2032616437","https://openalex.org/W2040084683","https://openalex.org/W2044859414","https://openalex.org/W2046694446","https://openalex.org/W2086676200","https://openalex.org/W2099637711","https://openalex.org/W2101345720","https://openalex.org/W2110922423","https://openalex.org/W2117803890","https://openalex.org/W2125055426","https://openalex.org/W2128688562","https://openalex.org/W2137079713","https://openalex.org/W2142475479","https://openalex.org/W2142584642","https://openalex.org/W2145277965","https://openalex.org/W2145482038","https://openalex.org/W2156098321","https://openalex.org/W2166187912","https://openalex.org/W2174328857","https://openalex.org/W2205558186","https://openalex.org/W2229870550","https://openalex.org/W2301180375","https://openalex.org/W2304359395","https://openalex.org/W2323932205","https://openalex.org/W2340922131","https://openalex.org/W2419378857","https://openalex.org/W2443260048","https://openalex.org/W2491185291","https://openalex.org/W2515929539","https://openalex.org/W2529177389","https://openalex.org/W2551226707","https://openalex.org/W2571745486","https://openalex.org/W2742634787","https://openalex.org/W2752417653","https://openalex.org/W2765381794","https://openalex.org/W2769644668","https://openalex.org/W2773697965","https://openalex.org/W2785321075","https://openalex.org/W2790286597","https://openalex.org/W2793104901","https://openalex.org/W2796226526","https://openalex.org/W2806398775","https://openalex.org/W2887802844","https://openalex.org/W2902276352","https://openalex.org/W2906081359","https://openalex.org/W2967272945","https://openalex.org/W2991792334","https://openalex.org/W3137993385","https://openalex.org/W4233740607","https://openalex.org/W4250251700","https://openalex.org/W4285719527","https://openalex.org/W4292994270","https://openalex.org/W4294215472","https://openalex.org/W6607370545","https://openalex.org/W6607917679","https://openalex.org/W6611879274","https://openalex.org/W6630239475","https://openalex.org/W6634722872","https://openalex.org/W6636084947","https://openalex.org/W6640027112","https://openalex.org/W6654323082","https://openalex.org/W6674865229","https://openalex.org/W6675165078","https://openalex.org/W6677753250","https://openalex.org/W6689380590","https://openalex.org/W6704022510","https://openalex.org/W6717377715","https://openalex.org/W6746184176","https://openalex.org/W6747345244","https://openalex.org/W6748008354","https://openalex.org/W6756169307","https://openalex.org/W6791702927"],"related_works":["https://openalex.org/W2046929026","https://openalex.org/W2779278343","https://openalex.org/W1996434451","https://openalex.org/W1569026615","https://openalex.org/W2791725133","https://openalex.org/W2338117633","https://openalex.org/W2112831187","https://openalex.org/W2122149485","https://openalex.org/W4232131108","https://openalex.org/W2128124510"],"abstract_inverted_index":{"OBJECTIVE:":[0],"The":[1],"study":[2],"sought":[3],"to":[4,34,80,219],"describe":[5],"the":[6,22,58,82,93,102,106,153,205,217],"literature":[7],"describing":[8,52,236],"clinical":[9,13],"reasoning":[10,26,135,190],"ontology":[11,124],"(CRO)-based":[12],"decision":[14,214],"support":[15],"systems":[16],"(CDSSs)":[17],"and":[18,20,25,28,41,78,89,108,137,143,183,192,195,233],"identify":[19],"classify":[21],"medical":[23,130,187,213],"knowledge":[24,119,131,188],"concepts":[27,88,208],"their":[29,111,165],"properties":[30,90,140,193],"within":[31,92],"these":[32],"ontologies":[33,112],"guide":[35],"future":[36],"research.":[37],"METHODS:":[38],"MEDLINE,":[39],"Scopus,":[40],"Google":[42],"Scholar":[43],"were":[44,66,70,121],"searched":[45],"through":[46],"January":[47],"30,":[48],"2019,":[49],"for":[50,72,101,123,231],"studies":[51,169,235],"CRO-based":[53,99,199],"CDSSs.":[54,200],"Articles":[55],"that":[56,204],"explored":[57],"development":[59,182],"or":[60,64],"application":[61],"of":[62,75,105,110,118,186,207],"CROs":[63,79,227,237],"terminology":[65],"selected.":[67],"Eligible":[68],"articles":[69],"assessed":[71],"quality":[73,172],"features":[74],"both":[76],"CDSSs":[77,100,247],"determine":[81],"current":[83,177],"practices.":[84],"We":[85,96,126,175],"then":[86],"compiled":[87],"used":[91,122,155,179,197,209,230],"articles.":[94],"RESULTS:":[95],"included":[97],"38":[98,133],"analysis.":[103],"Diversity":[104],"purpose":[107],"scope":[109],"was":[113],"seen,":[114],"with":[115],"a":[116,149,160],"variety":[117],"sources":[120],"development.":[125],"found":[127],"126":[128],"unique":[129,134,139],"concepts,":[132,136,189,191],"240":[138],"(137":[141],"relationships":[142],"103":[144],"attributes).":[145],"Although":[146],"there":[147,158],"is":[148,159,242],"great":[150],"diversity":[151],"among":[152],"terms":[154],"across":[156],"CROs,":[157],"significant":[161],"overlap":[162],"based":[163,248],"on":[164,249],"descriptions.":[166],"Only":[167],"5":[168],"described":[170],"high":[171],"assessment.":[173],"CONCLUSION:":[174],"identified":[176],"practices":[178],"in":[180,244],"CRO":[181,201],"provided":[184],"lists":[185],"(relationships":[194],"attributes)":[196],"by":[198,210],"developers":[202],"reason":[203],"inclusion":[206],"clinicians'":[211],"during":[212],"making":[215],"has":[216],"potential":[218],"improve":[220],"CDSS":[221],"performance.":[222],"However,":[223],"at":[224],"present,":[225],"few":[226],"have":[228],"been":[229],"CDSSs,":[232],"high-quality":[234,246],"are":[238],"sparse.":[239],"Further":[240],"research":[241],"required":[243],"developing":[245],"CROs.":[250]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":7}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}