{"id":"https://openalex.org/W2991843552","doi":"https://doi.org/10.1093/bioinformatics/btz898","title":"The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination","display_name":"The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination","publication_year":2019,"publication_date":"2019-11-27","ids":{"openalex":"https://openalex.org/W2991843552","doi":"https://doi.org/10.1093/bioinformatics/btz898","mag":"2991843552","pmid":"https://pubmed.ncbi.nlm.nih.gov/31790148"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz898","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz898","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/7/2217/33027393/btz898.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/7/2217/33027393/btz898.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081314217","display_name":"Kathryn A. McGurk","orcid":"https://orcid.org/0000-0002-5445-6906"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Kathryn A McGurk","raw_affiliation_strings":["Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, University of Manchester , Manchester, UK","Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry , UK","Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, University of Manchester , Manchester, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry , UK","institution_ids":[]},{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068449833","display_name":"Arianna Dagliati","orcid":"https://orcid.org/0000-0002-5041-0409"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Arianna Dagliati","raw_affiliation_strings":["Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester , UK"],"affiliations":[{"raw_affiliation_string":"Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester , UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037832617","display_name":"Davide Chiasserini","orcid":"https://orcid.org/0000-0002-1169-3258"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Davide Chiasserini","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079504262","display_name":"Dave Lee","orcid":"https://orcid.org/0000-0003-3367-5808"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dave Lee","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001906034","display_name":"Darren Plant","orcid":"https://orcid.org/0000-0003-1395-9344"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I4210092852","display_name":"Manchester University NHS Foundation Trust","ror":"https://ror.org/00he80998","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210092852"]},{"id":"https://openalex.org/I4210159460","display_name":"NIHR Manchester Biomedical Research Centre","ror":"https://ror.org/05njkjr15","country_code":"GB","type":"facility","lineage":["https://openalex.org/I34931013","https://openalex.org/I4210159460"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Darren Plant","raw_affiliation_strings":["NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust , Manchester, UK","institution_ids":["https://openalex.org/I4210092852","https://openalex.org/I2799725268","https://openalex.org/I4210159460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091249855","display_name":"Ivona Bari\u010devi\u0107-Jones","orcid":null},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ivona Baricevic-Jones","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005424368","display_name":"Janet Kelsall","orcid":null},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Janet Kelsall","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035713455","display_name":"Rachael Eineman","orcid":null},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rachael Eineman","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059516555","display_name":"Rachel Reed","orcid":"https://orcid.org/0000-0003-4202-1400"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Rachel Reed","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055126440","display_name":"Bethany Geary","orcid":"https://orcid.org/0000-0002-5592-5532"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bethany Geary","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022672574","display_name":"Richard D. Unwin","orcid":"https://orcid.org/0000-0001-7955-9111"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard D Unwin","raw_affiliation_strings":["Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, University of Manchester , Manchester, UK","Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, University of Manchester , Manchester, UK","institution_ids":["https://openalex.org/I28407311"]},{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005286924","display_name":"Anna Nicolaou","orcid":"https://orcid.org/0000-0002-1314-413X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anna Nicolaou","raw_affiliation_strings":["Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry , UK"],"affiliations":[{"raw_affiliation_string":"Laboratory for Lipidomics and Lipid Biology, Division of Pharmacy and Optometry , UK","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035095307","display_name":"Bernard Keavney","orcid":"https://orcid.org/0000-0001-9573-0812"},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Bernard D Keavney","raw_affiliation_strings":["Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, University of Manchester , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, University of Manchester , Manchester, UK","institution_ids":["https://openalex.org/I28407311"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025085488","display_name":"Anne Barton","orcid":"https://orcid.org/0000-0003-3316-2527"},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]},{"id":"https://openalex.org/I4210092852","display_name":"Manchester University NHS Foundation Trust","ror":"https://ror.org/00he80998","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210092852"]},{"id":"https://openalex.org/I4210117448","display_name":"Arthritis UK","ror":"https://ror.org/02jkpm469","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4210117448"]},{"id":"https://openalex.org/I4210151791","display_name":"Genomics (United Kingdom)","ror":"https://ror.org/053a6xa29","country_code":"GB","type":"company","lineage":["https://openalex.org/I4210151791"]},{"id":"https://openalex.org/I4210159460","display_name":"NIHR Manchester Biomedical Research Centre","ror":"https://ror.org/05njkjr15","country_code":"GB","type":"facility","lineage":["https://openalex.org/I34931013","https://openalex.org/I4210159460"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anne Barton","raw_affiliation_strings":["Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, University of Manchester , Manchester, UK","NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, University of Manchester , Manchester, UK","institution_ids":["https://openalex.org/I4210117448","https://openalex.org/I28407311","https://openalex.org/I4210151791"]},{"raw_affiliation_string":"NIHR Manchester Biomedical Research Centre, Manchester Academic Health Science Centre, Manchester University NHS Foundation Trust , Manchester, UK","institution_ids":["https://openalex.org/I4210092852","https://openalex.org/I2799725268","https://openalex.org/I4210159460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076360005","display_name":"Anthony D. Whetton","orcid":null},"institutions":[{"id":"https://openalex.org/I2799725268","display_name":"Manchester Academic Health Science Centre","ror":"https://ror.org/04rrkhs81","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799725268"]},{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Anthony D Whetton","raw_affiliation_strings":["Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK"],"affiliations":[{"raw_affiliation_string":"Stoller Biomarker Discovery Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre , Manchester, UK","institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060773682","display_name":"Nophar Geifman","orcid":null},"institutions":[{"id":"https://openalex.org/I28407311","display_name":"University of Manchester","ror":"https://ror.org/027m9bs27","country_code":"GB","type":"education","lineage":["https://openalex.org/I28407311"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Nophar Geifman","raw_affiliation_strings":["Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester , UK"],"affiliations":[{"raw_affiliation_string":"Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester , UK","institution_ids":["https://openalex.org/I28407311"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":16,"corresponding_author_ids":["https://openalex.org/A5060773682","https://openalex.org/A5081314217"],"corresponding_institution_ids":["https://openalex.org/I2799725268","https://openalex.org/I28407311"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":1.9824,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.85710903,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"36","issue":"7","first_page":"2217","last_page":"2223"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.9390444755554199},{"id":"https://openalex.org/keywords/outlier","display_name":"Outlier","score":0.566369891166687},{"id":"https://openalex.org/keywords/confidence-interval","display_name":"Confidence interval","score":0.5253286361694336},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.45844340324401855},{"id":"https://openalex.org/keywords/biomarker-discovery","display_name":"Biomarker discovery","score":0.45194318890571594},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.4422471523284912},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.38022956252098083},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.34810715913772583},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.26499128341674805},{"id":"https://openalex.org/keywords/proteomics","display_name":"Proteomics","score":0.2493779957294464},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.19357863068580627},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17411190271377563},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.15876039862632751}],"concepts":[{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.9390444755554199},{"id":"https://openalex.org/C79337645","wikidata":"https://www.wikidata.org/wiki/Q779824","display_name":"Outlier","level":2,"score":0.566369891166687},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5253286361694336},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.45844340324401855},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.45194318890571594},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4422471523284912},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.38022956252098083},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.34810715913772583},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.26499128341674805},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.2493779957294464},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.19357863068580627},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17411190271377563},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.15876039862632751},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1093/bioinformatics/btz898","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz898","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/7/2217/33027393/btz898.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31790148","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31790148","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pure.atira.dk:openaire/9a424af9-7fc4-45f6-82d9-0994904ad23e","is_oa":true,"landing_page_url":"https://research.manchester.ac.uk/en/publications/9a424af9-7fc4-45f6-82d9-0994904ad23e","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"McGurk, K, Dagliati, A, Chiasserini, D, Lee, D, Plant, D, Baricevic-Jones, I, Kelsall, J, Eineman, R, Reed, R, Geary, B, Unwin, R, Nicolaou, A, Keavney, B, Barton, A, Whetton, A & Geifman, N 2020, 'The use of missing values in proteomic data-independent acquisition mass spectrometry to enable disease activity discrimination', Bioinformatics, vol. 36, no. 7, pp. 2217-2223. https://doi.org/10.1093/bioinformatics/btz898","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:pubmedcentral.nih.gov:7141869","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7141869","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/98567","is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/98567","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"2223","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz898","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz898","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/7/2217/33027393/btz898.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.6000000238418579,"id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G1760579","display_name":null,"funder_award_id":"MR/M008959/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2343090476","display_name":null,"funder_award_id":"C5759/A25254","funder_id":"https://openalex.org/F4320329621","funder_display_name":"Cancer Research UK Manchester Centre"},{"id":"https://openalex.org/G4365314885","display_name":null,"funder_award_id":"MR/N00583X/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G5679402821","display_name":"Manchester Academic Health Science Centre Technology Hub: Clinical Proteomics Centre for Stratified Medicine","funder_award_id":"MR/M008959/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6168070217","display_name":null,"funder_award_id":"MR/N00583X/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G7897033027","display_name":null,"funder_award_id":"21754","funder_id":"https://openalex.org/F4320327444","funder_display_name":"Versus Arthritis"}],"funders":[{"id":"https://openalex.org/F4320327444","display_name":"Versus Arthritis","ror":"https://ror.org/02jkpm469"},{"id":"https://openalex.org/F4320329621","display_name":"Cancer Research UK Manchester Centre","ror":null},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2991843552.pdf","grobid_xml":"https://content.openalex.org/works/W2991843552.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W2000403772","https://openalex.org/W2016709601","https://openalex.org/W2018126724","https://openalex.org/W2045619021","https://openalex.org/W2064295826","https://openalex.org/W2079843936","https://openalex.org/W2082704080","https://openalex.org/W2100358124","https://openalex.org/W2103165230","https://openalex.org/W2110177517","https://openalex.org/W2114165700","https://openalex.org/W2139381960","https://openalex.org/W2155901917","https://openalex.org/W2167675918","https://openalex.org/W2171118759","https://openalex.org/W2278988761","https://openalex.org/W2498136312","https://openalex.org/W2529750106","https://openalex.org/W2567865325","https://openalex.org/W2605248799","https://openalex.org/W2747446612","https://openalex.org/W2783674487","https://openalex.org/W2790398313","https://openalex.org/W2791458756","https://openalex.org/W2810968367","https://openalex.org/W2896444124","https://openalex.org/W2909739147","https://openalex.org/W2929905027","https://openalex.org/W2951580700","https://openalex.org/W2951837249","https://openalex.org/W2964010366","https://openalex.org/W3015223320","https://openalex.org/W6684492424","https://openalex.org/W6731705029","https://openalex.org/W6736396672","https://openalex.org/W6743078358"],"related_works":["https://openalex.org/W112583468","https://openalex.org/W96119380","https://openalex.org/W3023706879","https://openalex.org/W4298030740","https://openalex.org/W4404588215","https://openalex.org/W2108949684","https://openalex.org/W4246773350","https://openalex.org/W1965976436","https://openalex.org/W2012655824","https://openalex.org/W3177170977"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1}],"updated_date":"2026-04-07T14:57:38.498316","created_date":"2025-10-10T00:00:00"}