{"id":"https://openalex.org/W2956050535","doi":"https://doi.org/10.1093/bioinformatics/btz535","title":"Isoform function prediction based on bi-random walks on a heterogeneous network","display_name":"Isoform function prediction based on bi-random walks on a heterogeneous network","publication_year":2019,"publication_date":"2019-06-26","ids":{"openalex":"https://openalex.org/W2956050535","doi":"https://doi.org/10.1093/bioinformatics/btz535","mag":"2956050535","pmid":"https://pubmed.ncbi.nlm.nih.gov/31250882"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz535","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz535","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027082940","display_name":"Guoxian Yu","orcid":"https://orcid.org/0000-0002-1667-6705"},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guoxian Yu","raw_affiliation_strings":["College of Computer and Information Science, Southwest University , Chongqing, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Science, Southwest University , Chongqing, China","institution_ids":["https://openalex.org/I142108993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110954531","display_name":"Keyao Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Keyao Wang","raw_affiliation_strings":["College of Computer and Information Science, Southwest University , Chongqing, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Science, Southwest University , Chongqing, China","institution_ids":["https://openalex.org/I142108993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090148962","display_name":"Carlotta Domeniconi","orcid":"https://orcid.org/0000-0003-2140-9596"},"institutions":[{"id":"https://openalex.org/I162714631","display_name":"George Mason University","ror":"https://ror.org/02jqj7156","country_code":"US","type":"education","lineage":["https://openalex.org/I162714631"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlotta Domeniconi","raw_affiliation_strings":["Department of Computer Science, George Mason University , Fairfax, VA 22030, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, George Mason University , Fairfax, VA 22030, USA","institution_ids":["https://openalex.org/I162714631"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079800756","display_name":"Maozu Guo","orcid":"https://orcid.org/0000-0001-6228-6276"},"institutions":[{"id":"https://openalex.org/I4210096250","display_name":"Beijing Institute of Big Data Research","ror":"https://ror.org/00s1sz824","country_code":"CN","type":"facility","lineage":["https://openalex.org/I20231570","https://openalex.org/I37796252","https://openalex.org/I4210096250"]},{"id":"https://openalex.org/I62853816","display_name":"Beijing University of Civil Engineering and Architecture","ror":"https://ror.org/02yj0p855","country_code":"CN","type":"education","lineage":["https://openalex.org/I62853816"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Maozu Guo","raw_affiliation_strings":["Beijing Key Laboratory of Intelligent Processing for Building Big Data, Beijing, China","School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture , Beijing, China"],"affiliations":[{"raw_affiliation_string":"Beijing Key Laboratory of Intelligent Processing for Building Big Data, Beijing, China","institution_ids":["https://openalex.org/I4210096250"]},{"raw_affiliation_string":"School of Electrical and Information Engineering, Beijing University of Civil Engineering and Architecture , Beijing, China","institution_ids":["https://openalex.org/I62853816"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100384767","display_name":"Jun Wang","orcid":"https://orcid.org/0000-0002-5890-0365"},"institutions":[{"id":"https://openalex.org/I142108993","display_name":"Southwest University","ror":"https://ror.org/01kj4z117","country_code":"CN","type":"education","lineage":["https://openalex.org/I142108993"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jun Wang","raw_affiliation_strings":["College of Computer and Information Science, Southwest University , Chongqing, China"],"affiliations":[{"raw_affiliation_string":"College of Computer and Information Science, Southwest University , Chongqing, China","institution_ids":["https://openalex.org/I142108993"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5079800756","https://openalex.org/A5100384767"],"corresponding_institution_ids":["https://openalex.org/I142108993","https://openalex.org/I4210096250","https://openalex.org/I62853816"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.3604,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.9396549,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"36","issue":"1","first_page":"303","last_page":"310"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10320","display_name":"Neural Networks and Applications","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10320","display_name":"Neural Networks and Applications","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10100","display_name":"Metaheuristic Optimization Algorithms Research","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9388999938964844,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/random-walk","display_name":"Random walk","score":0.7220041751861572},{"id":"https://openalex.org/keywords/gene-isoform","display_name":"Gene isoform","score":0.7160331010818481},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.6005940437316895},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.5423986911773682},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5381131768226624},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4339161217212677},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.36259135603904724},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.33302855491638184},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.32852083444595337},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3212786614894867},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.24562251567840576},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2040175497531891},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1813669502735138},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.16491004824638367},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.1556018590927124},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.12084582448005676},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08571377396583557}],"concepts":[{"id":"https://openalex.org/C121194460","wikidata":"https://www.wikidata.org/wiki/Q856741","display_name":"Random walk","level":2,"score":0.7220041751861572},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.7160331010818481},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.6005940437316895},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.5423986911773682},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5381131768226624},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4339161217212677},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.36259135603904724},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.33302855491638184},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.32852083444595337},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3212786614894867},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24562251567840576},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2040175497531891},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1813669502735138},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.16491004824638367},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1556018590927124},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.12084582448005676},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08571377396583557},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058977","descriptor_name":"Molecular Sequence Annotation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063990","descriptor_name":"Gene Ontology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btz535","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz535","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31250882","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31250882","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3605984960","display_name":null,"funder_award_id":"XDJK2019B024","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G3900474127","display_name":null,"funder_award_id":"61571163","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5564147583","display_name":null,"funder_award_id":"61872300","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G659245102","display_name":null,"funder_award_id":"61873214","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6640186486","display_name":null,"funder_award_id":"61532014","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7148930410","display_name":null,"funder_award_id":"61871020","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W1568341953","https://openalex.org/W1784654175","https://openalex.org/W1964362163","https://openalex.org/W2011920499","https://openalex.org/W2020541351","https://openalex.org/W2027266161","https://openalex.org/W2027898937","https://openalex.org/W2041399050","https://openalex.org/W2048827870","https://openalex.org/W2063176993","https://openalex.org/W2065128082","https://openalex.org/W2087201001","https://openalex.org/W2096173332","https://openalex.org/W2096998479","https://openalex.org/W2108745803","https://openalex.org/W2110119381","https://openalex.org/W2128128648","https://openalex.org/W2141889095","https://openalex.org/W2145287259","https://openalex.org/W2155804510","https://openalex.org/W2159451611","https://openalex.org/W2171184528","https://openalex.org/W2196447784","https://openalex.org/W2227395312","https://openalex.org/W2259938310","https://openalex.org/W2340098008","https://openalex.org/W2343974644","https://openalex.org/W2345998082","https://openalex.org/W2426363820","https://openalex.org/W2559588208","https://openalex.org/W2604808360","https://openalex.org/W2625968153","https://openalex.org/W2750771238","https://openalex.org/W2915536738","https://openalex.org/W4252684946","https://openalex.org/W6676245398"],"related_works":["https://openalex.org/W1540936366","https://openalex.org/W2079625624","https://openalex.org/W2004254765","https://openalex.org/W2126407448","https://openalex.org/W2125691904","https://openalex.org/W1597743604","https://openalex.org/W200174347","https://openalex.org/W4390692226","https://openalex.org/W1984231369","https://openalex.org/W2044512040"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}