{"id":"https://openalex.org/W2955255053","doi":"https://doi.org/10.1093/bioinformatics/btz467","title":"A dynamic programing approach to integrate gene expression data and network information for pathway model generation","display_name":"A dynamic programing approach to integrate gene expression data and network information for pathway model generation","publication_year":2019,"publication_date":"2019-05-31","ids":{"openalex":"https://openalex.org/W2955255053","doi":"https://doi.org/10.1093/bioinformatics/btz467","mag":"2955255053","pmid":"https://pubmed.ncbi.nlm.nih.gov/31168616"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz467","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz467","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/1/169/31813701/btz467.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/1/169/31813701/btz467.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112452050","display_name":"Yuexu Jiang","orcid":null},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yuexu Jiang","raw_affiliation_strings":["Department of Computer Science and Technology, Jilin University , Changchun 130012, China","Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Jilin University , Changchun 130012, China","institution_ids":["https://openalex.org/I194450716"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076665413","display_name":"Yanchun Liang","orcid":"https://orcid.org/0000-0002-1147-3968"},"institutions":[{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanchun Liang","raw_affiliation_strings":["Department of Computer Science and Technology, Jilin University , Changchun 130012, China"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Jilin University , Changchun 130012, China","institution_ids":["https://openalex.org/I194450716"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003943520","display_name":"Duolin Wang","orcid":"https://orcid.org/0000-0003-1649-460X"},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]},{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Duolin Wang","raw_affiliation_strings":["Department of Computer Science and Technology, Jilin University , Changchun 130012, China","Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Jilin University , Changchun 130012, China","institution_ids":["https://openalex.org/I194450716"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082428303","display_name":"Dong Xu","orcid":"https://orcid.org/0000-0002-4809-0514"},"institutions":[{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]},{"id":"https://openalex.org/I194450716","display_name":"Jilin University","ror":"https://ror.org/00js3aw79","country_code":"CN","type":"education","lineage":["https://openalex.org/I194450716"]}],"countries":["CN","US"],"is_corresponding":true,"raw_author_name":"Dong Xu","raw_affiliation_strings":["Department of Computer Science and Technology, Jilin University , Changchun 130012, China","Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA","Informatics Institute and Christopher S. Bond Life Sciences Center , Columbia, MO 65211, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Technology, Jilin University , Changchun 130012, China","institution_ids":["https://openalex.org/I194450716"]},{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Informatics Institute and Christopher S. Bond Life Sciences Center , Columbia, MO 65211, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071079252","display_name":"Trupti Joshi","orcid":"https://orcid.org/0000-0001-8944-4924"},"institutions":[{"id":"https://openalex.org/I2800649613","display_name":"University of Missouri Health System","ror":"https://ror.org/03yp8z857","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800649613"]},{"id":"https://openalex.org/I76835614","display_name":"University of Missouri","ror":"https://ror.org/02ymw8z06","country_code":"US","type":"education","lineage":["https://openalex.org/I76835614"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Trupti Joshi","raw_affiliation_strings":["Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA","Department of Health Management and Informatics, University of Missouri , Columbia, MO 65211, USA","Informatics Institute and Christopher S. Bond Life Sciences Center , Columbia, MO 65211, USA"],"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering and Computer Science , Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I76835614"]},{"raw_affiliation_string":"Department of Health Management and Informatics, University of Missouri , Columbia, MO 65211, USA","institution_ids":["https://openalex.org/I2800649613","https://openalex.org/I76835614"]},{"raw_affiliation_string":"Informatics Institute and Christopher S. Bond Life Sciences Center , Columbia, MO 65211, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5071079252","https://openalex.org/A5082428303"],"corresponding_institution_ids":["https://openalex.org/I194450716","https://openalex.org/I2800649613","https://openalex.org/I76835614"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.7671,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":{"value":0.70648849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"36","issue":"1","first_page":"169","last_page":"176"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7063926458358765},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.5372974276542664},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46337902545928955},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.42708659172058105},{"id":"https://openalex.org/keywords/gene-expression-programming","display_name":"Gene expression programming","score":0.4217315912246704},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4177165627479553},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3495292663574219},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3023858368396759},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.30127590894699097},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2175835371017456},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1776578426361084}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7063926458358765},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.5372974276542664},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46337902545928955},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.42708659172058105},{"id":"https://openalex.org/C6980683","wikidata":"https://www.wikidata.org/wiki/Q5531551","display_name":"Gene expression programming","level":2,"score":0.4217315912246704},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4177165627479553},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3495292663574219},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3023858368396759},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.30127590894699097},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2175835371017456},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1776578426361084}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008957","descriptor_name":"Models, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btz467","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz467","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/1/169/31813701/btz467.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31168616","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31168616","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz467","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz467","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/1/169/31813701/btz467.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6800000071525574,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1490688220","display_name":null,"funder_award_id":"# IOS-1444448","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6466047885","display_name":null,"funder_award_id":"# IOS-1546873","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2955255053.pdf","grobid_xml":"https://content.openalex.org/works/W2955255053.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W69703779","https://openalex.org/W1556555540","https://openalex.org/W1644724366","https://openalex.org/W1968667083","https://openalex.org/W1972129511","https://openalex.org/W1975035065","https://openalex.org/W1979996936","https://openalex.org/W1983601898","https://openalex.org/W2023639434","https://openalex.org/W2040847667","https://openalex.org/W2042778855","https://openalex.org/W2059747206","https://openalex.org/W2063928888","https://openalex.org/W2077631777","https://openalex.org/W2079187345","https://openalex.org/W2084294502","https://openalex.org/W2089691349","https://openalex.org/W2096173332","https://openalex.org/W2106863749","https://openalex.org/W2107953475","https://openalex.org/W2111862142","https://openalex.org/W2112811019","https://openalex.org/W2118258530","https://openalex.org/W2129265876","https://openalex.org/W2129770809","https://openalex.org/W2133074013","https://openalex.org/W2136303131","https://openalex.org/W2142433339","https://openalex.org/W2163480486","https://openalex.org/W2168846334","https://openalex.org/W2174632898","https://openalex.org/W2325767305","https://openalex.org/W2423570221","https://openalex.org/W2530896003","https://openalex.org/W2559588208","https://openalex.org/W2802392794","https://openalex.org/W3101256146","https://openalex.org/W3102022799"],"related_works":["https://openalex.org/W2358274547","https://openalex.org/W2120643273","https://openalex.org/W2357574271","https://openalex.org/W2350550488","https://openalex.org/W2091782719","https://openalex.org/W1968560158","https://openalex.org/W2316269051","https://openalex.org/W1982775134","https://openalex.org/W2133741237","https://openalex.org/W2352768576"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":5}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}