{"id":"https://openalex.org/W2796870706","doi":"https://doi.org/10.1093/bioinformatics/btz315","title":"Bayesian metabolic flux analysis reveals intracellular flux couplings","display_name":"Bayesian metabolic flux analysis reveals intracellular flux couplings","publication_year":2019,"publication_date":"2019-05-09","ids":{"openalex":"https://openalex.org/W2796870706","doi":"https://doi.org/10.1093/bioinformatics/btz315","mag":"2796870706","pmid":"https://pubmed.ncbi.nlm.nih.gov/31510676"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz315","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz315","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i548/28913576/btz315.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"preprint","indexed_in":["arxiv","crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i548/28913576/btz315.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101444999","display_name":"Markus Heinonen","orcid":"https://orcid.org/0000-0002-7741-2279"},"institutions":[{"id":"https://openalex.org/I32943570","display_name":"Helsinki Institute for Information Technology","ror":"https://ror.org/05kph4940","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I32943570","https://openalex.org/I9927081"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":true,"raw_author_name":"Markus Heinonen","raw_affiliation_strings":["Department of Computer Science, Aalto University, Espoo, Finland","Helsinki Institute for Information Technology, Espoo, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aalto University, Espoo, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Helsinki Institute for Information Technology, Espoo, Finland","institution_ids":["https://openalex.org/I32943570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086892490","display_name":"Maria Osmala","orcid":"https://orcid.org/0000-0003-0128-4896"},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Maria Osmala","raw_affiliation_strings":["Department of Computer Science, Aalto University, Espoo, Finland","Department of Computer Science, Aalto University Espoo Finland"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aalto University, Espoo, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Department of Computer Science, Aalto University Espoo Finland","institution_ids":["https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070900340","display_name":"Henrik Mannerstr\u00f6m","orcid":"https://orcid.org/0000-0001-8492-665X"},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Henrik Mannerstr\u00f6m","raw_affiliation_strings":["Department of Computer Science, Aalto University, Espoo, Finland","Department of Computer Science, Aalto University Espoo Finland"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aalto University, Espoo, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Department of Computer Science, Aalto University Espoo Finland","institution_ids":["https://openalex.org/I9927081"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014114149","display_name":"Janne Wallenius","orcid":"https://orcid.org/0000-0003-1786-4027"},"institutions":[{"id":"https://openalex.org/I4210133586","display_name":"Institute for Molecular Medicine Finland","ror":"https://ror.org/030sbze61","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I4210133586"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Janne Wallenius","raw_affiliation_strings":["Institute for Molecular Medicine Finland, Helsinki, Finland"],"affiliations":[{"raw_affiliation_string":"Institute for Molecular Medicine Finland, Helsinki, Finland","institution_ids":["https://openalex.org/I4210133586"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018305257","display_name":"Samuel Kaski","orcid":"https://orcid.org/0000-0003-1925-9154"},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]},{"id":"https://openalex.org/I32943570","display_name":"Helsinki Institute for Information Technology","ror":"https://ror.org/05kph4940","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I32943570","https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Samuel Kaski","raw_affiliation_strings":["Department of Computer Science, Aalto University, Espoo, Finland","Helsinki Institute for Information Technology, Espoo, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aalto University, Espoo, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Helsinki Institute for Information Technology, Espoo, Finland","institution_ids":["https://openalex.org/I32943570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091883185","display_name":"Juho Rousu","orcid":"https://orcid.org/0000-0002-0705-4314"},"institutions":[{"id":"https://openalex.org/I32943570","display_name":"Helsinki Institute for Information Technology","ror":"https://ror.org/05kph4940","country_code":"FI","type":"facility","lineage":["https://openalex.org/I133731052","https://openalex.org/I32943570","https://openalex.org/I9927081"]},{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Juho Rousu","raw_affiliation_strings":["Department of Computer Science, Aalto University, Espoo, Finland","Helsinki Institute for Information Technology, Espoo, Finland"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aalto University, Espoo, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Helsinki Institute for Information Technology, Espoo, Finland","institution_ids":["https://openalex.org/I32943570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049442192","display_name":"Harri L\u00e4hdesm\u00e4ki","orcid":"https://orcid.org/0000-0002-0373-139X"},"institutions":[{"id":"https://openalex.org/I9927081","display_name":"Aalto University","ror":"https://ror.org/020hwjq30","country_code":"FI","type":"education","lineage":["https://openalex.org/I9927081"]}],"countries":["FI"],"is_corresponding":false,"raw_author_name":"Harri L\u00e4hdesm\u00e4ki","raw_affiliation_strings":["Department of Computer Science, Aalto University, Espoo, Finland","Department of Computer Science, Aalto University Espoo Finland"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Aalto University, Espoo, Finland","institution_ids":["https://openalex.org/I9927081"]},{"raw_affiliation_string":"Department of Computer Science, Aalto University Espoo Finland","institution_ids":["https://openalex.org/I9927081"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5101444999"],"corresponding_institution_ids":["https://openalex.org/I32943570","https://openalex.org/I9927081"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.1718,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.51089943,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"35","issue":"14","first_page":"i548","last_page":"i557"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10171","display_name":"Biofuel production and bioconversion","score":0.9896000027656555,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flux-balance-analysis","display_name":"Flux balance analysis","score":0.8904725313186646},{"id":"https://openalex.org/keywords/metabolic-flux-analysis","display_name":"Metabolic flux analysis","score":0.8251394033432007},{"id":"https://openalex.org/keywords/flux","display_name":"Flux (metallurgy)","score":0.6994248628616333},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.5014820098876953},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.46976399421691895},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.44387632608413696},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.35271698236465454},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.3483142852783203},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3331329822540283},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.23690015077590942},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.18397730588912964},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1771363914012909},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.11747866868972778},{"id":"https://openalex.org/keywords/metabolism","display_name":"Metabolism","score":0.07317531108856201}],"concepts":[{"id":"https://openalex.org/C167091322","wikidata":"https://www.wikidata.org/wiki/Q5463029","display_name":"Flux balance analysis","level":2,"score":0.8904725313186646},{"id":"https://openalex.org/C160941953","wikidata":"https://www.wikidata.org/wiki/Q6822342","display_name":"Metabolic flux analysis","level":3,"score":0.8251394033432007},{"id":"https://openalex.org/C68709404","wikidata":"https://www.wikidata.org/wiki/Q1134475","display_name":"Flux (metallurgy)","level":2,"score":0.6994248628616333},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.5014820098876953},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.46976399421691895},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.44387632608413696},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.35271698236465454},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.3483142852783203},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3331329822540283},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.23690015077590942},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.18397730588912964},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1771363914012909},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.11747866868972778},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.07317531108856201},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D046969","descriptor_name":"Clostridium acetobutylicum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046969","descriptor_name":"Clostridium acetobutylicum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046969","descriptor_name":"Clostridium acetobutylicum","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053858","descriptor_name":"Metabolic Networks and Pathways","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064688","descriptor_name":"Metabolic Flux Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064688","descriptor_name":"Metabolic Flux Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D064688","descriptor_name":"Metabolic Flux Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":8,"locations":[{"id":"doi:10.1093/bioinformatics/btz315","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz315","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i548/28913576/btz315.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:31510676","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31510676","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pure.atira.dk:openaire/dc78b9d6-51e6-4701-a16e-c609bf237d77","is_oa":false,"landing_page_url":"https://research.manchester.ac.uk/en/publications/dc78b9d6-51e6-4701-a16e-c609bf237d77","pdf_url":null,"source":{"id":"https://openalex.org/S4306400662","display_name":"Research Explorer (The University of Manchester)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I28407311","host_organization_name":"University of Manchester","host_organization_lineage":["https://openalex.org/I28407311"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Heinonen, M, Osmala, M, Mannerstr\u00f6m, H, Wallenius, J, Kaski, S, Rousu, J & L\u00e4hdesm\u00e4ki, H 2019, 'Bayesian metabolic flux analysis reveals intracellular flux couplings', Bioinformatics, vol. 35, no. 14, btz315, pp. i548-i557. https://doi.org/10.1093/bioinformatics/btz315","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:arXiv.org:1804.06673","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1804.06673","pdf_url":"https://arxiv.org/pdf/1804.06673","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"mag:2796870706","is_oa":true,"landing_page_url":"https://arxiv.org/pdf/1804.06673v1","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"arXiv (Cornell University)","raw_type":null},{"id":"pmh:oai:aaltodoc.aalto.fi:123456789/39488","is_oa":true,"landing_page_url":"https://research.aalto.fi/en/publications/ac8fc5b4-f160-46fc-b47c-e8c576ec6cd0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401663","display_name":"Aaltodoc (Aalto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I9927081","host_organization_name":"Aalto University","host_organization_lineage":["https://openalex.org/I9927081"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"publishedVersion"},{"id":"pmh:oai:europepmc.org:5588740","is_oa":false,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6612884","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"doi:10.48550/arxiv.1804.06673","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.1804.06673","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz315","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz315","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/14/i548/28913576/btz315.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G17168737","display_name":null,"funder_award_id":"313271","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G3902535387","display_name":null,"funder_award_id":"299915","funder_id":"https://openalex.org/F4320321108","funder_display_name":"Academy of Finland"},{"id":"https://openalex.org/G4029575243","display_name":null,"funder_award_id":"40128/14","funder_id":"https://openalex.org/F4320321855","funder_display_name":"Tekes"}],"funders":[{"id":"https://openalex.org/F4320321108","display_name":"Academy of Finland","ror":"https://ror.org/05k73zm37"},{"id":"https://openalex.org/F4320321726","display_name":"Suomen Kulttuurirahasto","ror":"https://ror.org/027xav248"},{"id":"https://openalex.org/F4320321855","display_name":"Tekes","ror":"https://ror.org/02ag8cq23"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2796870706.pdf","grobid_xml":"https://content.openalex.org/works/W2796870706.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W180233418","https://openalex.org/W1158629448","https://openalex.org/W1977927025","https://openalex.org/W1978408474","https://openalex.org/W2011514820","https://openalex.org/W2015519162","https://openalex.org/W2016431642","https://openalex.org/W2018158121","https://openalex.org/W2029403511","https://openalex.org/W2030776070","https://openalex.org/W2034942872","https://openalex.org/W2039993828","https://openalex.org/W2044935306","https://openalex.org/W2050807896","https://openalex.org/W2051378923","https://openalex.org/W2075283200","https://openalex.org/W2076262841","https://openalex.org/W2077195032","https://openalex.org/W2078355959","https://openalex.org/W2085893390","https://openalex.org/W2107628565","https://openalex.org/W2119642783","https://openalex.org/W2120469353","https://openalex.org/W2125299871","https://openalex.org/W2127393884","https://openalex.org/W2134117233","https://openalex.org/W2135476401","https://openalex.org/W2138429195","https://openalex.org/W2147472054","https://openalex.org/W2148534890","https://openalex.org/W2161642788","https://openalex.org/W2288838258","https://openalex.org/W2345887956","https://openalex.org/W2461742269","https://openalex.org/W2471096355","https://openalex.org/W2481120998","https://openalex.org/W2583438419","https://openalex.org/W2599070308","https://openalex.org/W2736080104","https://openalex.org/W2951331864","https://openalex.org/W3106380050","https://openalex.org/W4235508806","https://openalex.org/W4238101851","https://openalex.org/W4248681815"],"related_works":["https://openalex.org/W2050807896","https://openalex.org/W89125745","https://openalex.org/W2041174099","https://openalex.org/W158765010","https://openalex.org/W3198839594","https://openalex.org/W2883468939","https://openalex.org/W3210388257","https://openalex.org/W3049656521","https://openalex.org/W2737230856","https://openalex.org/W2735233379","https://openalex.org/W20786471","https://openalex.org/W2086196945","https://openalex.org/W18034897","https://openalex.org/W2108592854","https://openalex.org/W2470338435","https://openalex.org/W1897809568","https://openalex.org/W2519089746","https://openalex.org/W2233183256","https://openalex.org/W2076262841","https://openalex.org/W2226658599"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}