{"id":"https://openalex.org/W2908677338","doi":"https://doi.org/10.1093/bioinformatics/btz012","title":"A web application and service for imputing and visualizing missense variant effect maps","display_name":"A web application and service for imputing and visualizing missense variant effect maps","publication_year":2019,"publication_date":"2019-01-09","ids":{"openalex":"https://openalex.org/W2908677338","doi":"https://doi.org/10.1093/bioinformatics/btz012","mag":"2908677338","pmid":"https://pubmed.ncbi.nlm.nih.gov/30649215"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btz012","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz012","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/17/3191/29591965/btz012.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/35/17/3191/29591965/btz012.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073246971","display_name":"Yingzhou Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Yingzhou Wu","raw_affiliation_strings":["Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Department of Computer Science, , Toronto, ON, Canada","University of Toronto Department of Molecular Genetics, , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Department of Computer Science, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"University of Toronto Department of Molecular Genetics, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020856251","display_name":"Jochen Weile","orcid":"https://orcid.org/0000-0003-1628-9390"},"institutions":[{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jochen Weile","raw_affiliation_strings":["Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Department of Computer Science, , Toronto, ON, Canada","University of Toronto Department of Molecular Genetics, , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Department of Computer Science, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"University of Toronto Department of Molecular Genetics, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000800469","display_name":"Atina G. Cot\u00e9","orcid":"https://orcid.org/0000-0002-0340-9325"},"institutions":[{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Atina G Cote","raw_affiliation_strings":["Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104247503","display_name":"Song Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Song Sun","raw_affiliation_strings":["Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024701006","display_name":"Jennifer J. Knapp","orcid":"https://orcid.org/0000-0003-3347-4686"},"institutions":[{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Jennifer Knapp","raw_affiliation_strings":["Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067800333","display_name":"Marta Verby","orcid":null},"institutions":[{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Marta Verby","raw_affiliation_strings":["Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090936599","display_name":"Frederick P. Roth","orcid":"https://orcid.org/0000-0002-6628-649X"},"institutions":[{"id":"https://openalex.org/I210557978","display_name":"Lunenfeld-Tanenbaum Research Institute","ror":"https://ror.org/01s5axj25","country_code":"CA","type":"facility","lineage":["https://openalex.org/I1291836623","https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I109736498","display_name":"Canadian Institute for Advanced Research","ror":"https://ror.org/01sdtdd95","country_code":"CA","type":"facility","lineage":["https://openalex.org/I109736498"]},{"id":"https://openalex.org/I4210130843","display_name":"Sinai Health System","ror":"https://ror.org/044790d95","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210130843"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["CA","US"],"is_corresponding":true,"raw_author_name":"Frederick P Roth","raw_affiliation_strings":["Canadian Institute for Advanced Research , Toronto, ON, Canada","Center for Cancer Systems Biology, Dana Farber Cancer Institute , Boston, MA, USA","Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","University of Toronto Department of Computer Science, , Toronto, ON, Canada","University of Toronto Department of Molecular Genetics, , Toronto, ON, Canada","University of Toronto Donnelly Centre, , Toronto, ON, Canada"],"affiliations":[{"raw_affiliation_string":"Canadian Institute for Advanced Research , Toronto, ON, Canada","institution_ids":["https://openalex.org/I109736498"]},{"raw_affiliation_string":"Center for Cancer Systems Biology, Dana Farber Cancer Institute , Boston, MA, USA","institution_ids":["https://openalex.org/I4210117453"]},{"raw_affiliation_string":"Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto, ON, Canada","institution_ids":["https://openalex.org/I210557978","https://openalex.org/I4210130843"]},{"raw_affiliation_string":"University of Toronto Department of Computer Science, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"University of Toronto Department of Molecular Genetics, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"University of Toronto Donnelly Centre, , Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5090936599"],"corresponding_institution_ids":["https://openalex.org/I109736498","https://openalex.org/I185261750","https://openalex.org/I210557978","https://openalex.org/I4210117453","https://openalex.org/I4210130843"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":1.9693,"has_fulltext":false,"cited_by_count":24,"citation_normalized_percentile":{"value":0.86417875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"35","issue":"17","first_page":"3191","last_page":"3193"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/missense-mutation","display_name":"Missense mutation","score":0.8257869482040405},{"id":"https://openalex.org/keywords/imputation","display_name":"Imputation (statistics)","score":0.7946488857269287},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6418168544769287},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.5632690787315369},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5248304009437561},{"id":"https://openalex.org/keywords/source-code","display_name":"Source code","score":0.49181655049324036},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4755501449108124},{"id":"https://openalex.org/keywords/web-service","display_name":"Web service","score":0.4368608593940735},{"id":"https://openalex.org/keywords/missing-data","display_name":"Missing data","score":0.42358678579330444},{"id":"https://openalex.org/keywords/open-source","display_name":"Open source","score":0.42111191153526306},{"id":"https://openalex.org/keywords/exome","display_name":"Exome","score":0.4155963361263275},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.40873947739601135},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24707776308059692},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.22692930698394775},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.20722082257270813},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.18723264336585999},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.16083940863609314},{"id":"https://openalex.org/keywords/exome-sequencing","display_name":"Exome sequencing","score":0.1570080816745758},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11780419945716858},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.10087522864341736}],"concepts":[{"id":"https://openalex.org/C75563809","wikidata":"https://www.wikidata.org/wiki/Q2656896","display_name":"Missense mutation","level":4,"score":0.8257869482040405},{"id":"https://openalex.org/C58041806","wikidata":"https://www.wikidata.org/wiki/Q1660484","display_name":"Imputation (statistics)","level":3,"score":0.7946488857269287},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6418168544769287},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.5632690787315369},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5248304009437561},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.49181655049324036},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4755501449108124},{"id":"https://openalex.org/C35578498","wikidata":"https://www.wikidata.org/wiki/Q193424","display_name":"Web service","level":2,"score":0.4368608593940735},{"id":"https://openalex.org/C9357733","wikidata":"https://www.wikidata.org/wiki/Q6878417","display_name":"Missing data","level":2,"score":0.42358678579330444},{"id":"https://openalex.org/C3018397939","wikidata":"https://www.wikidata.org/wiki/Q3644502","display_name":"Open source","level":3,"score":0.42111191153526306},{"id":"https://openalex.org/C10590036","wikidata":"https://www.wikidata.org/wiki/Q417664","display_name":"Exome","level":5,"score":0.4155963361263275},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40873947739601135},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24707776308059692},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.22692930698394775},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.20722082257270813},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18723264336585999},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.16083940863609314},{"id":"https://openalex.org/C16671776","wikidata":"https://www.wikidata.org/wiki/Q5420592","display_name":"Exome sequencing","level":4,"score":0.1570080816745758},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11780419945716858},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.10087522864341736}],"mesh":[{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btz012","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz012","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/17/3191/29591965/btz012.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:30649215","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30649215","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:europepmc.org:5704529","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6735881","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btz012","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btz012","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/35/17/3191/29591965/btz012.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320994","display_name":"Canada Research Chairs","ror":"https://ror.org/0517h6h17"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2908677338.pdf","grobid_xml":"https://content.openalex.org/works/W2908677338.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1563940013","https://openalex.org/W2060588922","https://openalex.org/W2089335658","https://openalex.org/W2096892933","https://openalex.org/W2139365100","https://openalex.org/W2143210482","https://openalex.org/W2154139219","https://openalex.org/W2164004777","https://openalex.org/W2296846617","https://openalex.org/W2752403657","https://openalex.org/W2770026599","https://openalex.org/W2774216375","https://openalex.org/W2781028774","https://openalex.org/W2885278423","https://openalex.org/W4210702584","https://openalex.org/W6633589378"],"related_works":["https://openalex.org/W2181530120","https://openalex.org/W4211215373","https://openalex.org/W2024529227","https://openalex.org/W1574575415","https://openalex.org/W3144172081","https://openalex.org/W3179858851","https://openalex.org/W3028371478","https://openalex.org/W2081476516","https://openalex.org/W2581984549","https://openalex.org/W3123177881"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3}],"updated_date":"2026-03-21T08:13:44.787528","created_date":"2025-10-10T00:00:00"}