{"id":"https://openalex.org/W2625052417","doi":"https://doi.org/10.1093/bioinformatics/btx389","title":"The interfacial character of antibody paratopes: analysis of antibody\u2013antigen structures","display_name":"The interfacial character of antibody paratopes: analysis of antibody\u2013antigen structures","publication_year":2017,"publication_date":"2017-06-13","ids":{"openalex":"https://openalex.org/W2625052417","doi":"https://doi.org/10.1093/bioinformatics/btx389","mag":"2625052417","pmid":"https://pubmed.ncbi.nlm.nih.gov/28633399"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btx389","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx389","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/33/19/2971/25164917/btx389.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/33/19/2971/25164917/btx389.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101415930","display_name":"Minh N. Nguyen","orcid":"https://orcid.org/0000-0003-4949-2571"},"institutions":[{"id":"https://openalex.org/I4210148498","display_name":"Bioinformatics Institute","ror":"https://ror.org/044w3nw43","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210148498"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Minh N Nguyen","raw_affiliation_strings":["Bioinformatics Institute, Singapore"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Institute, Singapore","institution_ids":["https://openalex.org/I4210148498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078894133","display_name":"Mohan R. Pradhan","orcid":"https://orcid.org/0000-0001-9759-1676"},"institutions":[{"id":"https://openalex.org/I4210148498","display_name":"Bioinformatics Institute","ror":"https://ror.org/044w3nw43","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210148498"]},{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Mohan R Pradhan","raw_affiliation_strings":["Bioinformatics Institute, Singapore","School of Computer Engineering, Nanyang Technological University, Singapore"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Institute, Singapore","institution_ids":["https://openalex.org/I4210148498"]},{"raw_affiliation_string":"School of Computer Engineering, Nanyang Technological University, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045760818","display_name":"Chandra Verma","orcid":"https://orcid.org/0000-0003-0733-9798"},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]},{"id":"https://openalex.org/I4210148498","display_name":"Bioinformatics Institute","ror":"https://ror.org/044w3nw43","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I4210148498"]},{"id":"https://openalex.org/I172675005","display_name":"Nanyang Technological University","ror":"https://ror.org/02e7b5302","country_code":"SG","type":"education","lineage":["https://openalex.org/I172675005"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Chandra Verma","raw_affiliation_strings":["Bioinformatics Institute, Singapore","Department of Biological Sciences, National University of Singapore, Singapore","School of Biological Sciences, Nanyang Technological University, Singapore"],"affiliations":[{"raw_affiliation_string":"Bioinformatics Institute, Singapore","institution_ids":["https://openalex.org/I4210148498"]},{"raw_affiliation_string":"Department of Biological Sciences, National University of Singapore, Singapore","institution_ids":["https://openalex.org/I165932596"]},{"raw_affiliation_string":"School of Biological Sciences, Nanyang Technological University, Singapore","institution_ids":["https://openalex.org/I172675005"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072986704","display_name":"Pingyu Zhong","orcid":null},"institutions":[{"id":"https://openalex.org/I2800824516","display_name":"Singapore Immunology Network","ror":"https://ror.org/03vmmgg57","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2800824516","https://openalex.org/I2801752549"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Pingyu Zhong","raw_affiliation_strings":["Singapore Immunology Network (SIgN), Singapore"],"affiliations":[{"raw_affiliation_string":"Singapore Immunology Network (SIgN), Singapore","institution_ids":["https://openalex.org/I2800824516"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5045760818","https://openalex.org/A5072986704","https://openalex.org/A5101415930"],"corresponding_institution_ids":["https://openalex.org/I165932596","https://openalex.org/I172675005","https://openalex.org/I2800824516","https://openalex.org/I4210148498"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":4.5124,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.94864271,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"33","issue":"19","first_page":"2971","last_page":"2976"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paratope","display_name":"Paratope","score":0.9286787509918213},{"id":"https://openalex.org/keywords/antigen","display_name":"Antigen","score":0.6317524909973145},{"id":"https://openalex.org/keywords/epitope","display_name":"Epitope","score":0.6230357885360718},{"id":"https://openalex.org/keywords/antibody","display_name":"Antibody","score":0.5538283586502075},{"id":"https://openalex.org/keywords/hydrogen-bond","display_name":"Hydrogen bond","score":0.4879412353038788},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.4811740815639496},{"id":"https://openalex.org/keywords/van-der-waals-force","display_name":"van der Waals force","score":0.4363034963607788},{"id":"https://openalex.org/keywords/molecule","display_name":"Molecule","score":0.3590465188026428},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3481476306915283},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.25637155771255493},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.1565491259098053}],"concepts":[{"id":"https://openalex.org/C9086966","wikidata":"https://www.wikidata.org/wiki/Q489135","display_name":"Paratope","level":4,"score":0.9286787509918213},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6317524909973145},{"id":"https://openalex.org/C195616568","wikidata":"https://www.wikidata.org/wiki/Q128711","display_name":"Epitope","level":3,"score":0.6230357885360718},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5538283586502075},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.4879412353038788},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4811740815639496},{"id":"https://openalex.org/C126061179","wikidata":"https://www.wikidata.org/wiki/Q189627","display_name":"van der Waals force","level":3,"score":0.4363034963607788},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.3590465188026428},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3481476306915283},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.25637155771255493},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1565491259098053},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000939","descriptor_name":"Epitopes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001666","descriptor_name":"Binding Sites, Antibody","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001666","descriptor_name":"Binding Sites, Antibody","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001666","descriptor_name":"Binding Sites, Antibody","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006860","descriptor_name":"Hydrogen Bonding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btx389","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx389","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/33/19/2971/25164917/btx389.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:28633399","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28633399","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btx389","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btx389","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/33/19/2971/25164917/btx389.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Clean water and sanitation","score":0.75,"id":"https://metadata.un.org/sdg/6"}],"awards":[{"id":"https://openalex.org/G5005294873","display_name":null,"funder_award_id":"NRF2013-THE001-070","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G5678286893","display_name":null,"funder_award_id":"NRF2013-THE001-070","funder_id":"https://openalex.org/F4320333169","funder_display_name":"National Science Foundation, United Arab Emirates"},{"id":"https://openalex.org/G889111504","display_name":null,"funder_award_id":"15302FG145","funder_id":"https://openalex.org/F4320320696","funder_display_name":"Agency for Science, Technology and Research"}],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320320696","display_name":"Agency for Science, Technology and Research","ror":"https://ror.org/036wvzt09"},{"id":"https://openalex.org/F4320333169","display_name":"National Science Foundation, United Arab Emirates","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2625052417.pdf","grobid_xml":"https://content.openalex.org/works/W2625052417.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W974281930","https://openalex.org/W1978090240","https://openalex.org/W1985153601","https://openalex.org/W1992124716","https://openalex.org/W1997875463","https://openalex.org/W2007054796","https://openalex.org/W2018470704","https://openalex.org/W2023455361","https://openalex.org/W2031132894","https://openalex.org/W2037936747","https://openalex.org/W2039092320","https://openalex.org/W2055764905","https://openalex.org/W2057222401","https://openalex.org/W2065283382","https://openalex.org/W2072854137","https://openalex.org/W2083445427","https://openalex.org/W2099451628","https://openalex.org/W2110036226","https://openalex.org/W2110505462","https://openalex.org/W2112194058","https://openalex.org/W2116489181","https://openalex.org/W2117569373","https://openalex.org/W2117757241","https://openalex.org/W2129060396","https://openalex.org/W2132580736","https://openalex.org/W2132629607","https://openalex.org/W2142840682","https://openalex.org/W2146868760","https://openalex.org/W2158347168","https://openalex.org/W2159382632","https://openalex.org/W2167338363"],"related_works":["https://openalex.org/W2972990938","https://openalex.org/W2100617793","https://openalex.org/W2037745559","https://openalex.org/W4210635245","https://openalex.org/W2103053267","https://openalex.org/W2521166570","https://openalex.org/W4250653039","https://openalex.org/W4283010788","https://openalex.org/W4241393631","https://openalex.org/W2355952544"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":15},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}