{"id":"https://openalex.org/W2307454292","doi":"https://doi.org/10.1093/bioinformatics/btw094","title":"Multilevel biological characterization of exomic variants at the protein level significantly improves the identification of their deleterious effects","display_name":"Multilevel biological characterization of exomic variants at the protein level significantly improves the identification of their deleterious effects","publication_year":2016,"publication_date":"2016-02-18","ids":{"openalex":"https://openalex.org/W2307454292","doi":"https://doi.org/10.1093/bioinformatics/btw094","mag":"2307454292","pmid":"https://pubmed.ncbi.nlm.nih.gov/27153718"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btw094","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw094","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020836177","display_name":"Daniele Raimondi","orcid":"https://orcid.org/0000-0003-1157-1899"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]},{"id":"https://openalex.org/I4210140355","display_name":"VIB-VUB Center for Structural Biology","ror":"https://ror.org/03e84cm85","country_code":"BE","type":"facility","lineage":["https://openalex.org/I13469542","https://openalex.org/I2802017950","https://openalex.org/I4210140355"]},{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Daniele Raimondi","raw_affiliation_strings":["1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","2 Machine Learning Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium","3 Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium","4 Structural Biology Research Centre, VIB, Brussels 1050, Belgium","Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium"],"affiliations":[{"raw_affiliation_string":"1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","institution_ids":[]},{"raw_affiliation_string":"2 Machine Learning Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I132053463"]},{"raw_affiliation_string":"3 Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"4 Structural Biology Research Centre, VIB, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I4210140355"]},{"raw_affiliation_string":"Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036719753","display_name":"Andrea Gazzo","orcid":"https://orcid.org/0009-0009-9282-4667"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Andrea M. Gazzo","raw_affiliation_strings":["1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","2 Machine Learning Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium"],"affiliations":[{"raw_affiliation_string":"1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","institution_ids":[]},{"raw_affiliation_string":"2 Machine Learning Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073330873","display_name":"Marianne Rooman","orcid":"https://orcid.org/0000-0002-3810-7802"},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Marianne Rooman","raw_affiliation_strings":["1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","5 3BIO-BioInfo Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium"],"affiliations":[{"raw_affiliation_string":"1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","institution_ids":[]},{"raw_affiliation_string":"5 3BIO-BioInfo Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003581663","display_name":"Tom Lenaerts","orcid":"https://orcid.org/0000-0003-3645-1455"},"institutions":[{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]},{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Tom Lenaerts","raw_affiliation_strings":["1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","2 Machine Learning Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium","6 Artificial Intelligence Lab, Vrije Universiteit Brussel, Brussels 1050, Belgium","Artificial Intelligence Lab, Vrije Universiteit Brussel, Brussels 1050, Belgium"],"affiliations":[{"raw_affiliation_string":"1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","institution_ids":[]},{"raw_affiliation_string":"2 Machine Learning Group, Universit\u00e9 Libre De Bruxelles, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I132053463"]},{"raw_affiliation_string":"6 Artificial Intelligence Lab, Vrije Universiteit Brussel, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"Artificial Intelligence Lab, Vrije Universiteit Brussel, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I13469542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050454940","display_name":"Wim Vranken","orcid":"https://orcid.org/0000-0001-7470-4324"},"institutions":[{"id":"https://openalex.org/I4210140355","display_name":"VIB-VUB Center for Structural Biology","ror":"https://ror.org/03e84cm85","country_code":"BE","type":"facility","lineage":["https://openalex.org/I13469542","https://openalex.org/I2802017950","https://openalex.org/I4210140355"]},{"id":"https://openalex.org/I13469542","display_name":"Vrije Universiteit Brussel","ror":"https://ror.org/006e5kg04","country_code":"BE","type":"education","lineage":["https://openalex.org/I13469542"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Wim F. Vranken","raw_affiliation_strings":["1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","3 Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium","4 Structural Biology Research Centre, VIB, Brussels 1050, Belgium"],"affiliations":[{"raw_affiliation_string":"1 Interuniversity Institute of Bioinformatics in Brussels, ULB-VUB, Brussels 1050, Belgium","institution_ids":[]},{"raw_affiliation_string":"3 Structural Biology Brussels, Vrije Universiteit Brussel, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I13469542"]},{"raw_affiliation_string":"4 Structural Biology Research Centre, VIB, Brussels 1050, Belgium","institution_ids":["https://openalex.org/I4210140355"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5020836177"],"corresponding_institution_ids":["https://openalex.org/I132053463","https://openalex.org/I13469542","https://openalex.org/I4210140355"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":5.1074,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.95077561,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"32","issue":"12","first_page":"1797","last_page":"1804"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/indel","display_name":"Indel","score":0.8667767643928528},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6046419739723206},{"id":"https://openalex.org/keywords/missense-mutation","display_name":"Missense mutation","score":0.5491063594818115},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5314249992370605},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.5188918709754944},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5162394046783447},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.411133736371994},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.3298340439796448}],"concepts":[{"id":"https://openalex.org/C119054055","wikidata":"https://www.wikidata.org/wiki/Q1576681","display_name":"Indel","level":5,"score":0.8667767643928528},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6046419739723206},{"id":"https://openalex.org/C75563809","wikidata":"https://www.wikidata.org/wiki/Q2656896","display_name":"Missense mutation","level":4,"score":0.5491063594818115},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5314249992370605},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5188918709754944},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5162394046783447},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.411133736371994},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.3298340439796448},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014644","descriptor_name":"Genetic Variation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030562","descriptor_name":"Databases, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054643","descriptor_name":"INDEL Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054643","descriptor_name":"INDEL Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054643","descriptor_name":"INDEL Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":7,"locations":[{"id":"doi:10.1093/bioinformatics/btw094","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btw094","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:27153718","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27153718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:dipot.ulb.ac.be:2013/236692","is_oa":false,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/236692","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, 32 (12","raw_type":"info:ulb-repo/semantics/openurl/article"},{"id":"pmh:oai:dipot.ulb.ac.be:2013/243712","is_oa":false,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/243712","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"In: Proceedings of the European Conference on Computational Biology","raw_type":"info:ulb-repo/semantics/openurl/document"},{"id":"pmh:oai:open-archive.highwire.org:bioinfo:32/12/1797","is_oa":false,"landing_page_url":"http://bioinformatics.oxfordjournals.org/cgi/content/short/32/12/1797","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:135096","is_oa":false,"landing_page_url":"https://biblio.vub.ac.be/vubir/multilevel-biological-characterization-of-exomic-variants-at-the-protein-level-significantly-improves-the-identification-of-their-deleterious-effects(66c25c49-a2d5-4c9c-952a-0d9c63913171).html","pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:vubissmart:VUBISSMART:2000:250639","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402573","display_name":"VUBIR (Vrije Universiteit Brussel)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I13469542","host_organization_name":"Vrije Universiteit Brussel","host_organization_lineage":["https://openalex.org/I13469542"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7099999785423279,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W1483242733","https://openalex.org/W1683278196","https://openalex.org/W1971835681","https://openalex.org/W1971938921","https://openalex.org/W1973878786","https://openalex.org/W1980171391","https://openalex.org/W1984576497","https://openalex.org/W1987754412","https://openalex.org/W1992880766","https://openalex.org/W1998120162","https://openalex.org/W2010595044","https://openalex.org/W2017138237","https://openalex.org/W2038473742","https://openalex.org/W2042586732","https://openalex.org/W2054185647","https://openalex.org/W2059145105","https://openalex.org/W2061596350","https://openalex.org/W2076357933","https://openalex.org/W2079982314","https://openalex.org/W2085072319","https://openalex.org/W2086072858","https://openalex.org/W2087588809","https://openalex.org/W2089335658","https://openalex.org/W2089903000","https://openalex.org/W2090247362","https://openalex.org/W2091535494","https://openalex.org/W2096791516","https://openalex.org/W2097889307","https://openalex.org/W2101234009","https://openalex.org/W2103931879","https://openalex.org/W2109293787","https://openalex.org/W2111326065","https://openalex.org/W2119097398","https://openalex.org/W2122732537","https://openalex.org/W2127006085","https://openalex.org/W2127300788","https://openalex.org/W2129952088","https://openalex.org/W2136961040","https://openalex.org/W2138122982","https://openalex.org/W2141104259","https://openalex.org/W2143602768","https://openalex.org/W2154595610","https://openalex.org/W2157057843","https://openalex.org/W2160995259","https://openalex.org/W2161978970","https://openalex.org/W2163721943","https://openalex.org/W2164004777","https://openalex.org/W2172034373","https://openalex.org/W2911964244","https://openalex.org/W3150991593","https://openalex.org/W6648400570","https://openalex.org/W6661085122","https://openalex.org/W6672994547","https://openalex.org/W6675354045"],"related_works":["https://openalex.org/W2033001683","https://openalex.org/W2046457574","https://openalex.org/W2167094946","https://openalex.org/W4285059642","https://openalex.org/W4382398022","https://openalex.org/W1949458596","https://openalex.org/W3144677376","https://openalex.org/W32785519","https://openalex.org/W2061730343","https://openalex.org/W4206968815"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":2}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}