{"id":"https://openalex.org/W2161075095","doi":"https://doi.org/10.1093/bioinformatics/bts568","title":"\u2018Location, Location, Location\u2019: a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate","display_name":"\u2018Location, Location, Location\u2019: a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate","publication_year":2012,"publication_date":"2012-10-08","ids":{"openalex":"https://openalex.org/W2161075095","doi":"https://doi.org/10.1093/bioinformatics/bts568","mag":"2161075095","pmid":"https://pubmed.ncbi.nlm.nih.gov/23044548"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/bts568","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts568","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/23/3027/6137629/bts568.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/28/23/3027/6137629/bts568.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008728483","display_name":"Heide Fier","orcid":"https://orcid.org/0000-0002-7214-1764"},"institutions":[{"id":"https://openalex.org/I4210151238","display_name":"Center for Genomic Science","ror":"https://ror.org/04xbkmk86","country_code":"IT","type":"facility","lineage":["https://openalex.org/I30771326","https://openalex.org/I4210151238"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE","IT","KR"],"is_corresponding":true,"raw_author_name":"Heide Fier","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com","Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany. heide.fier@googlemail.com","institution_ids":["https://openalex.org/I4210151238"]},{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087186763","display_name":"Sungho Won","orcid":"https://orcid.org/0000-0001-5751-5089"},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Sungho Won","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019016063","display_name":"Dmitry Prokopenko","orcid":"https://orcid.org/0000-0002-1844-5652"},"institutions":[{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Dmitry Prokopenko","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003356704","display_name":"Taofik AlChawa","orcid":null},"institutions":[{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Taofik AlChawa","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073431929","display_name":"Kerstin U. Ludwig","orcid":"https://orcid.org/0000-0002-8541-2519"},"institutions":[{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Kerstin U. Ludwig","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042159993","display_name":"Rolf Fimmers","orcid":null},"institutions":[{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Rolf Fimmers","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035524361","display_name":"Edwin K. Silverman","orcid":"https://orcid.org/0000-0002-3641-3822"},"institutions":[{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]},{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Edwin K. Silverman","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034919044","display_name":"Michele Pagano","orcid":"https://orcid.org/0000-0003-3210-2442"},"institutions":[{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]},{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Marcello Pagano","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070927271","display_name":"Elisabeth Mangold","orcid":"https://orcid.org/0000-0002-3819-2576"},"institutions":[{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]},{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Elisabeth Mangold","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002736890","display_name":"Christoph Lange","orcid":"https://orcid.org/0000-0003-2620-1030"},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]},{"id":"https://openalex.org/I4210164436","display_name":"Life & Brain (Germany)","ror":"https://ror.org/05h6av881","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210164436"]},{"id":"https://openalex.org/I67900169","display_name":"Chung-Ang University","ror":"https://ror.org/01r024a98","country_code":"KR","type":"education","lineage":["https://openalex.org/I67900169"]}],"countries":["DE","KR"],"is_corresponding":false,"raw_author_name":"Christoph Lange","raw_affiliation_strings":["Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA"],"affiliations":[{"raw_affiliation_string":"Department of Genomic Mathematics, University of Bonn, 53127, Germany, 2Department of Applied Statistics, 3The Research Center for Data Science, Chung-Ang University, Seoul, 156-756, Korea, 4Institute of Human Genetics, 5Department of Genomics, Life and Brain Center, 6Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Bonn 53127, Germany and 7Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA","institution_ids":["https://openalex.org/I67900169","https://openalex.org/I4210164436","https://openalex.org/I135140700"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5008728483"],"corresponding_institution_ids":["https://openalex.org/I135140700","https://openalex.org/I4210151238","https://openalex.org/I4210164436","https://openalex.org/I67900169"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":2.0706,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.87796472,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"28","issue":"23","first_page":"3027","last_page":"3033"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11374","display_name":"Cleft Lip and Palate Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11374","display_name":"Cleft Lip and Palate Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.983299970626831,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9761999845504761,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.738017201423645},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5645059943199158},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.47579798102378845},{"id":"https://openalex.org/keywords/statistic","display_name":"Statistic","score":0.47402599453926086},{"id":"https://openalex.org/keywords/chromosome","display_name":"Chromosome","score":0.4535958170890808},{"id":"https://openalex.org/keywords/curse-of-dimensionality","display_name":"Curse of dimensionality","score":0.41413530707359314},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.39381295442581177},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.35277533531188965},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.34162649512290955},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.30521905422210693},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18677881360054016},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.1741289496421814}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.738017201423645},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5645059943199158},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.47579798102378845},{"id":"https://openalex.org/C89128539","wikidata":"https://www.wikidata.org/wiki/Q1949963","display_name":"Statistic","level":2,"score":0.47402599453926086},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.4535958170890808},{"id":"https://openalex.org/C111030470","wikidata":"https://www.wikidata.org/wiki/Q1430460","display_name":"Curse of dimensionality","level":2,"score":0.41413530707359314},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.39381295442581177},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.35277533531188965},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.34162649512290955},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.30521905422210693},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18677881360054016},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.1741289496421814},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000002","qualifier_name":"abnormalities","is_major_topic":false},{"descriptor_ui":"D002884","descriptor_name":"Chromosomes, Human, Pair 15","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002884","descriptor_name":"Chromosomes, Human, Pair 15","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002884","descriptor_name":"Chromosomes, Human, Pair 15","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002971","descriptor_name":"Cleft Lip","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002971","descriptor_name":"Cleft Lip","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002971","descriptor_name":"Cleft Lip","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002972","descriptor_name":"Cleft Palate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002972","descriptor_name":"Cleft Palate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002972","descriptor_name":"Cleft Palate","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005787","descriptor_name":"Gene Frequency","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/bts568","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts568","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/23/3027/6137629/bts568.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:23044548","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23044548","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:dash.harvard.edu:1/10587968","is_oa":true,"landing_page_url":"http://nrs.harvard.edu/urn-3:HUL.InstRepos:10587968","pdf_url":null,"source":{"id":"https://openalex.org/S4306401540","display_name":"Digital Access to Scholarship at Harvard (DASH) (Harvard University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I136199984","host_organization_name":"Harvard University","host_organization_lineage":["https://openalex.org/I136199984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2517386","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3516147","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/bts568","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/bts568","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/28/23/3027/6137629/bts568.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2161075095.pdf","grobid_xml":"https://content.openalex.org/works/W2161075095.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W98546445","https://openalex.org/W1967296216","https://openalex.org/W1970707782","https://openalex.org/W1971102564","https://openalex.org/W1973123998","https://openalex.org/W1980991473","https://openalex.org/W1987493079","https://openalex.org/W1995016401","https://openalex.org/W1996549154","https://openalex.org/W2024791049","https://openalex.org/W2029387902","https://openalex.org/W2058148991","https://openalex.org/W2070984858","https://openalex.org/W2074531605","https://openalex.org/W2086799994","https://openalex.org/W2093636770","https://openalex.org/W2101983393","https://openalex.org/W2117916987","https://openalex.org/W2138020005","https://openalex.org/W2141541691","https://openalex.org/W2142080241","https://openalex.org/W2159421729","https://openalex.org/W2159998163","https://openalex.org/W2163953557","https://openalex.org/W2171986838"],"related_works":["https://openalex.org/W4296209631","https://openalex.org/W2561617217","https://openalex.org/W2359776416","https://openalex.org/W4294811468","https://openalex.org/W2355801475","https://openalex.org/W106004901","https://openalex.org/W2353788488","https://openalex.org/W2170062176","https://openalex.org/W2316648939","https://openalex.org/W2804364458"],"abstract_inverted_index":{"heide.fier@googlemail.com.":[0]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}