{"id":"https://openalex.org/W2149491227","doi":"https://doi.org/10.1093/bioinformatics/btr136","title":"COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method","display_name":"COSINE: COndition-SpecIfic sub-NEtwork identification using a global optimization method","publication_year":2011,"publication_date":"2011-03-16","ids":{"openalex":"https://openalex.org/W2149491227","doi":"https://doi.org/10.1093/bioinformatics/btr136","mag":"2149491227","pmid":"https://pubmed.ncbi.nlm.nih.gov/21414987"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btr136","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btr136","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/27/9/1290/48868096/bioinformatics_27_9_1290.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/27/9/1290/48868096/bioinformatics_27_9_1290.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043651523","display_name":"Haisu Ma","orcid":null},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I68554272","display_name":"Pacific Biosciences (United States)","ror":"https://ror.org/00fcszb13","country_code":"US","type":"company","lineage":["https://openalex.org/I68554272"]},{"id":"https://openalex.org/I1323236076","display_name":"Sage Bionetworks","ror":"https://ror.org/049ncjx51","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1323236076"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Haisu Ma","raw_affiliation_strings":["1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA"],"affiliations":[{"raw_affiliation_string":"1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA","institution_ids":["https://openalex.org/I68554272","https://openalex.org/I136199984","https://openalex.org/I32971472","https://openalex.org/I4210087915","https://openalex.org/I1323236076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071946434","display_name":"Eric E. Schadt","orcid":"https://orcid.org/0000-0002-7892-8808"},"institutions":[{"id":"https://openalex.org/I1323236076","display_name":"Sage Bionetworks","ror":"https://ror.org/049ncjx51","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1323236076"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I68554272","display_name":"Pacific Biosciences (United States)","ror":"https://ror.org/00fcszb13","country_code":"US","type":"company","lineage":["https://openalex.org/I68554272"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric E. Schadt","raw_affiliation_strings":["1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA"],"affiliations":[{"raw_affiliation_string":"1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA","institution_ids":["https://openalex.org/I68554272","https://openalex.org/I136199984","https://openalex.org/I32971472","https://openalex.org/I4210087915","https://openalex.org/I1323236076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074635579","display_name":"Lee M. Kaplan","orcid":"https://orcid.org/0000-0002-6301-2696"},"institutions":[{"id":"https://openalex.org/I1323236076","display_name":"Sage Bionetworks","ror":"https://ror.org/049ncjx51","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1323236076"]},{"id":"https://openalex.org/I68554272","display_name":"Pacific Biosciences (United States)","ror":"https://ror.org/00fcszb13","country_code":"US","type":"company","lineage":["https://openalex.org/I68554272"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lee M. Kaplan","raw_affiliation_strings":["1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA"],"affiliations":[{"raw_affiliation_string":"1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA","institution_ids":["https://openalex.org/I68554272","https://openalex.org/I136199984","https://openalex.org/I32971472","https://openalex.org/I4210087915","https://openalex.org/I1323236076"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038681550","display_name":"Hongyu Zhao","orcid":"https://orcid.org/0000-0003-1477-5731"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I1323236076","display_name":"Sage Bionetworks","ror":"https://ror.org/049ncjx51","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1323236076"]},{"id":"https://openalex.org/I68554272","display_name":"Pacific Biosciences (United States)","ror":"https://ror.org/00fcszb13","country_code":"US","type":"company","lineage":["https://openalex.org/I68554272"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hongyu Zhao","raw_affiliation_strings":["1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA"],"affiliations":[{"raw_affiliation_string":"1 Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, 2Sage Bionetworks, Seattle, WA and Pacific Biosciences, Menlo Park, CA 94025, 3Gastrointestinal Unit and MGH Weight Center, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA 02114 and 4Department of Epidemiology and Public Health, Department of Genetics, Yale University, New Haven, CT 06520, USA","institution_ids":["https://openalex.org/I68554272","https://openalex.org/I136199984","https://openalex.org/I32971472","https://openalex.org/I4210087915","https://openalex.org/I1323236076"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5038681550"],"corresponding_institution_ids":["https://openalex.org/I1323236076","https://openalex.org/I136199984","https://openalex.org/I32971472","https://openalex.org/I4210087915","https://openalex.org/I68554272"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":3.335,"has_fulltext":true,"cited_by_count":99,"citation_normalized_percentile":{"value":0.93047138,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"27","issue":"9","first_page":"1290","last_page":"1298"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9783999919891357,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6462110280990601},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6095770597457886},{"id":"https://openalex.org/keywords/cosine-similarity","display_name":"Cosine similarity","score":0.5912775993347168},{"id":"https://openalex.org/keywords/relevance","display_name":"Relevance (law)","score":0.5154448747634888},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.49504581093788147},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.44608181715011597},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.44361361861228943},{"id":"https://openalex.org/keywords/r-package","display_name":"R package","score":0.42006444931030273},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.41224175691604614},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.32725855708122253},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.32583534717559814},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.28595033288002014},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.15827086567878723}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6462110280990601},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6095770597457886},{"id":"https://openalex.org/C2780762811","wikidata":"https://www.wikidata.org/wiki/Q1784941","display_name":"Cosine similarity","level":3,"score":0.5912775993347168},{"id":"https://openalex.org/C158154518","wikidata":"https://www.wikidata.org/wiki/Q7310970","display_name":"Relevance (law)","level":2,"score":0.5154448747634888},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.49504581093788147},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.44608181715011597},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44361361861228943},{"id":"https://openalex.org/C2984074130","wikidata":"https://www.wikidata.org/wiki/Q73539779","display_name":"R package","level":2,"score":0.42006444931030273},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.41224175691604614},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32725855708122253},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.32583534717559814},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.28595033288002014},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.15827086567878723},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C459310","wikidata":"https://www.wikidata.org/wiki/Q117801","display_name":"Computational science","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D053263","descriptor_name":"Gene Regulatory Networks","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D060148","descriptor_name":"HapMap Project","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060148","descriptor_name":"HapMap Project","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060148","descriptor_name":"HapMap Project","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/bioinformatics/btr136","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btr136","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/27/9/1290/48868096/bioinformatics_27_9_1290.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:21414987","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21414987","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.859.105","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.859.105","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://bioinformatics.oxfordjournals.org/content/early/2011/03/15/bioinformatics.btr136.full.pdf","raw_type":"text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3138081","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3138081","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btr136","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btr136","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/27/9/1290/48868096/bioinformatics_27_9_1290.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G630330811","display_name":null,"funder_award_id":"GM59507","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320308380","display_name":"Yale University","ror":"https://ror.org/03v76x132"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2149491227.pdf","grobid_xml":"https://content.openalex.org/works/W2149491227.grobid-xml"},"referenced_works_count":52,"referenced_works":["https://openalex.org/W1535333477","https://openalex.org/W1588398650","https://openalex.org/W1592316676","https://openalex.org/W1593128362","https://openalex.org/W1966327575","https://openalex.org/W1969779540","https://openalex.org/W1974886995","https://openalex.org/W1981637710","https://openalex.org/W1983463159","https://openalex.org/W1999720425","https://openalex.org/W2010707723","https://openalex.org/W2018377599","https://openalex.org/W2038234348","https://openalex.org/W2060199889","https://openalex.org/W2067213500","https://openalex.org/W2070412833","https://openalex.org/W2083045667","https://openalex.org/W2097498614","https://openalex.org/W2104300284","https://openalex.org/W2107953475","https://openalex.org/W2108022229","https://openalex.org/W2112087830","https://openalex.org/W2112811019","https://openalex.org/W2113962581","https://openalex.org/W2114954827","https://openalex.org/W2119220491","https://openalex.org/W2120051475","https://openalex.org/W2120842170","https://openalex.org/W2122683221","https://openalex.org/W2122863289","https://openalex.org/W2123699903","https://openalex.org/W2130410032","https://openalex.org/W2133512719","https://openalex.org/W2134672568","https://openalex.org/W2137200212","https://openalex.org/W2139845570","https://openalex.org/W2141407136","https://openalex.org/W2145290999","https://openalex.org/W2150091098","https://openalex.org/W2154452346","https://openalex.org/W2157997136","https://openalex.org/W2158217645","https://openalex.org/W2158270719","https://openalex.org/W2162243457","https://openalex.org/W2168474259","https://openalex.org/W2916288174","https://openalex.org/W4213212078","https://openalex.org/W4236293524","https://openalex.org/W4249273120","https://openalex.org/W6635179103","https://openalex.org/W6635476249","https://openalex.org/W6680991062"],"related_works":["https://openalex.org/W2085384747","https://openalex.org/W2106071040","https://openalex.org/W2088166309","https://openalex.org/W4312133475","https://openalex.org/W4238976562","https://openalex.org/W2276587472","https://openalex.org/W4248323080","https://openalex.org/W2615795876","https://openalex.org/W2049612369","https://openalex.org/W4214571255"],"abstract_inverted_index":{"The":[0],"R":[1],"code":[2],"is":[3],"available":[4],"as":[5],"the":[6],"COSINE":[7],"package":[8],"on":[9],"CRAN:":[10],"http://cran.r-project.org/web/packages/COSINE/index.html.":[11]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":9},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":6}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}