{"id":"https://openalex.org/W2167884443","doi":"https://doi.org/10.1093/bioinformatics/btq253","title":"Prediction of protein\u2013RNA binding sites by a random forest method with combined features","display_name":"Prediction of protein\u2013RNA binding sites by a random forest method with combined features","publication_year":2010,"publication_date":"2010-05-18","ids":{"openalex":"https://openalex.org/W2167884443","doi":"https://doi.org/10.1093/bioinformatics/btq253","mag":"2167884443","pmid":"https://pubmed.ncbi.nlm.nih.gov/20483814"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btq253","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq253","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/13/1616/16894335/btq253.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/26/13/1616/16894335/btq253.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100742066","display_name":"Zhiping Liu","orcid":"https://orcid.org/0000-0001-7272-6917"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210120485","display_name":"Academy of Mathematics and Systems Science","ror":"https://ror.org/02jkmyk67","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120485"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhi-Ping Liu","raw_affiliation_strings":["1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I4210120485","https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042263308","display_name":"Ling\u2010Yun Wu","orcid":"https://orcid.org/0000-0001-9487-0215"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210120485","display_name":"Academy of Mathematics and Systems Science","ror":"https://ror.org/02jkmyk67","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120485"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ling-Yun Wu","raw_affiliation_strings":["1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I4210120485","https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100424555","display_name":"Yong Wang","orcid":"https://orcid.org/0000-0003-4177-5462"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210120485","display_name":"Academy of Mathematics and Systems Science","ror":"https://ror.org/02jkmyk67","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120485"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Wang","raw_affiliation_strings":["1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I4210120485","https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiang-Sun Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210120485","display_name":"Academy of Mathematics and Systems Science","ror":"https://ror.org/02jkmyk67","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120485"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiang-Sun Zhang","raw_affiliation_strings":["1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I4210120485","https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012283696","display_name":"Luonan Chen","orcid":"https://orcid.org/0000-0002-3960-0068"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210106477","display_name":"Shanghai Institutes for Biological Sciences","ror":"https://ror.org/011rf9d86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210106477"]},{"id":"https://openalex.org/I4210120485","display_name":"Academy of Mathematics and Systems Science","ror":"https://ror.org/02jkmyk67","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210120485"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Luonan Chen","raw_affiliation_strings":["1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1 Key Laboratory of Systems Biology, SIBS-Novo Nordisk Translational Research Centre for PreDiabetes, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031 and 2 Academy of Mathematics and Systems Science, Chinese Academy of Sciences, Beijing 100190, China","institution_ids":["https://openalex.org/I4210120485","https://openalex.org/I19820366","https://openalex.org/I4210106477"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5012283696"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210106477","https://openalex.org/I4210120485"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":5.1505,"has_fulltext":true,"cited_by_count":160,"citation_normalized_percentile":{"value":0.96330451,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"26","issue":"13","first_page":"1616","last_page":"1622"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.761185348033905},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5609921813011169},{"id":"https://openalex.org/keywords/rna-binding-protein","display_name":"RNA-binding protein","score":0.5229775905609131},{"id":"https://openalex.org/keywords/ribosome","display_name":"Ribosome","score":0.5179149508476257},{"id":"https://openalex.org/keywords/binding-site","display_name":"Binding site","score":0.45169517397880554},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.41919419169425964},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.3749288320541382},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.33086466789245605},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.19297176599502563}],"concepts":[{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.761185348033905},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5609921813011169},{"id":"https://openalex.org/C41282012","wikidata":"https://www.wikidata.org/wiki/Q3928341","display_name":"RNA-binding protein","level":4,"score":0.5229775905609131},{"id":"https://openalex.org/C88478588","wikidata":"https://www.wikidata.org/wiki/Q42244","display_name":"Ribosome","level":4,"score":0.5179149508476257},{"id":"https://openalex.org/C107824862","wikidata":"https://www.wikidata.org/wiki/Q616005","display_name":"Binding site","level":2,"score":0.45169517397880554},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.41919419169425964},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3749288320541382},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.33086466789245605},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.19297176599502563}],"mesh":[{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016601","descriptor_name":"RNA-Binding Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020539","descriptor_name":"Sequence Analysis, Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bioinformatics/btq253","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq253","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/13/1616/16894335/btq253.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:20483814","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20483814","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btq253","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btq253","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/26/13/1616/16894335/btq253.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Reduced inequalities","score":0.5699999928474426,"id":"https://metadata.un.org/sdg/10"}],"awards":[{"id":"https://openalex.org/G50557974","display_name":null,"funder_award_id":"10631070","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5782751608","display_name":null,"funder_award_id":"2006CB503905","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6495355840","display_name":null,"funder_award_id":"2009CSP002","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321133","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35"},{"id":"https://openalex.org/F4320321530","display_name":"Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences","ror":"https://ror.org/011rf9d86"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2167884443.pdf","grobid_xml":"https://content.openalex.org/works/W2167884443.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W273955616","https://openalex.org/W1494641947","https://openalex.org/W1924414119","https://openalex.org/W1971894358","https://openalex.org/W1974275047","https://openalex.org/W1979762151","https://openalex.org/W1984574291","https://openalex.org/W1984882637","https://openalex.org/W1997953216","https://openalex.org/W2003122343","https://openalex.org/W2007922755","https://openalex.org/W2008708467","https://openalex.org/W2015175027","https://openalex.org/W2019853549","https://openalex.org/W2027119345","https://openalex.org/W2029918421","https://openalex.org/W2044775131","https://openalex.org/W2050625197","https://openalex.org/W2061685714","https://openalex.org/W2079873244","https://openalex.org/W2089621332","https://openalex.org/W2097694646","https://openalex.org/W2101590367","https://openalex.org/W2110304798","https://openalex.org/W2119493141","https://openalex.org/W2125471137","https://openalex.org/W2130479394","https://openalex.org/W2139262886","https://openalex.org/W2144476269","https://openalex.org/W2158714788","https://openalex.org/W2161062388","https://openalex.org/W2168055922","https://openalex.org/W2168272116","https://openalex.org/W2911964244","https://openalex.org/W4211054902","https://openalex.org/W6610017368","https://openalex.org/W6640102280"],"related_works":["https://openalex.org/W1499159835","https://openalex.org/W2066254905","https://openalex.org/W1993362141","https://openalex.org/W1968948161","https://openalex.org/W1598137697","https://openalex.org/W2569356794","https://openalex.org/W4379233576","https://openalex.org/W2753172052","https://openalex.org/W3080365360","https://openalex.org/W1935063092"],"abstract_inverted_index":{"MOTIVATION:":[0],"Protein-RNA":[1],"interactions":[2,52,286],"play":[3],"a":[4,8,27,29,37,55,96,110,127,131,145,182,203,227],"key":[5],"role":[6],"in":[7,73,106,144,178,202,267,284,297],"number":[9],"of":[10,32,36,49,82,130,157,168,211,214,218,221,280,292,305],"biological":[11,275],"processes,":[12],"such":[13,244,257],"as":[14,151,153,245,258],"protein":[15,38,132,146],"synthesis,":[16],"mRNA":[17,19],"processing,":[18],"assembly,":[20],"ribosome":[21],"function":[22],"and":[23,44,87,119,216,235,249,251,264,282,300,313],"eukaryotic":[24],"spliceosomes.":[25],"As":[26],"result,":[28],"reliable":[30],"identification":[31],"RNA":[33,56,70,88,103,137,175,223,232,240],"binding":[34,57,104,128,224,233,241,303],"site":[35],"is":[39,193],"important":[40],"for":[41,68,226,294],"functional":[42],"annotation":[43],"site-directed":[45],"mutagenesis.":[46],"Accumulated":[47],"data":[48,312,326],"experimental":[50],"protein-RNA":[51,199,285],"reveal":[53],"that":[54,190],"residue":[58,133,147,242],"with":[59,116,171],"different":[60,66],"neighbor":[61],"amino":[62,84,169],"acids":[63,170],"often":[64],"exhibits":[65],"preferences":[67],"its":[69,141],"partners,":[71],"which":[72],"turn":[74],"can":[75],"be":[76],"assessed":[77],"by":[78,108,139,180,287],"the":[79,83,102,123,135,154,158,165,197,222,268,278,290,302,310],"interacting":[80,112,136,176,306],"interdependence":[81],"acid":[85],"fragment":[86],"nucleotide.":[89],"RESULTS:":[90],"In":[91],"this":[92],"work,":[93],"we":[94,272],"propose":[95],"novel":[97],"classification":[98],"method":[99,192,207],"to":[100,134,163,195],"identify":[101],"sites":[105,201],"proteins":[107,179],"combining":[109],"new":[111],"feature":[113],"(interaction":[114],"propensity)":[115],"other":[117],"sequence-":[118],"structure-based":[120,155],"features.":[121],"Specifically,":[122],"interaction":[124,166,200],"propensity":[125,167],"represents":[126],"specificity":[129],"nucleotide":[138],"considering":[140],"two-side":[142],"neighborhood":[143],"triplet.":[148],"The":[149,187],"sequence":[150],"well":[152],"features":[156,293],"residues":[159,177,225],"are":[160,315,327],"combined":[161],"together":[162],"discriminate":[164],"RNA.":[172],"We":[173],"predict":[174],"implementing":[181],"well-built":[183],"random":[184],"forest":[185],"classifier.":[186],"experiments":[188],"show":[189],"our":[191],"able":[194],"detect":[196],"annotated":[198],"high":[204],"accuracy.":[205],"Our":[206],"achieves":[208],"an":[209],"accuracy":[210,299],"84.5%,":[212],"F-measure":[213],"0.85":[215],"AUC":[217],"0.92":[219],"prediction":[220],"dataset":[228],"containing":[229],"205":[230],"non-homologous":[231],"proteins,":[234],"also":[236],"outperforms":[237],"several":[238],"existing":[239],"predictors,":[243],"RNABindR,":[246],"BindN,":[247],"RNAProB":[248],"PPRint,":[250],"some":[252,274],"alternative":[253],"machine":[254],"learning":[255],"methods,":[256],"support":[259],"vector":[260],"machine,":[261],"naive":[262],"Bayes":[263],"neural":[265],"network":[266],"comparison":[269],"study.":[270],"Furthermore,":[271],"provide":[273],"insights":[276],"into":[277],"roles":[279],"sequences":[281],"structures":[283],"both":[288],"evaluating":[289],"importance":[291],"their":[295],"contributions":[296],"predictive":[298],"analyzing":[301],"patterns":[304],"residues.":[307],"AVAILABILITY:":[308],"All":[309],"source":[311],"code":[314],"available":[316,328],"at":[317,329],"http://www.aporc.org/doc/wiki/PRNA":[318],"or":[319],"http://www.sysbio.ac.cn/datatools.asp":[320],"CONTACT:":[321],"lnchen@sibs.ac.cn":[322],"SUPPLEMENTARY":[323],"INFORMATION:":[324],"Supplementary":[325],"Bioinformatics":[330],"online.":[331]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":14},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":14},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":19},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":11}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-10-10T00:00:00"}