{"id":"https://openalex.org/W4402100103","doi":"https://doi.org/10.1093/bioinformatics/btae536","title":"Signature Search Polestar: a comprehensive drug repurposing method evaluation assistant for customized oncogenic signature","display_name":"Signature Search Polestar: a comprehensive drug repurposing method evaluation assistant for customized oncogenic signature","publication_year":2024,"publication_date":"2024-08-29","ids":{"openalex":"https://openalex.org/W4402100103","doi":"https://doi.org/10.1093/bioinformatics/btae536","pmid":"https://pubmed.ncbi.nlm.nih.gov/39213324"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btae536","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae536","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae536/58979114/btae536.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae536/58979114/btae536.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110384966","display_name":"Jinbo Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210142182","display_name":"Tianjin Hospital","ror":"https://ror.org/04j9yn198","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142182"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jinbo Zhang","raw_affiliation_strings":["Department of Pharmacy, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China","Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Pharmacy, , Tianjin, 300110, China"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","institution_ids":["https://openalex.org/I4210142182"]},{"raw_affiliation_string":"Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Pharmacy, , Tianjin, 300110, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006518103","display_name":"Shunling Yuan","orcid":null},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shunling Yuan","raw_affiliation_strings":["Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China"],"affiliations":[{"raw_affiliation_string":"Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011510207","display_name":"Wen Cao","orcid":"https://orcid.org/0000-0002-1882-5620"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wen Cao","raw_affiliation_strings":["Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China"],"affiliations":[{"raw_affiliation_string":"Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113106446","display_name":"Xianrui Jiang","orcid":null},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xianrui Jiang","raw_affiliation_strings":["Changhai Hospital, Second Military Medical University , Shanghai 200433, China","Changhai Hospital, Second Military Medical University , Shanghai, 200433, China"],"affiliations":[{"raw_affiliation_string":"Changhai Hospital, Second Military Medical University , Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]},{"raw_affiliation_string":"Changhai Hospital, Second Military Medical University , Shanghai, 200433, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013811376","display_name":"Cheng Yang","orcid":"https://orcid.org/0000-0001-9431-290X"},"institutions":[{"id":"https://openalex.org/I4210165501","display_name":"Pingjin Hospital","ror":"https://ror.org/05szq2344","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210165501"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng Yang","raw_affiliation_strings":["Department of Clinical Nutrition, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Clinical Nutrition, , Tianjin, 300110, China"],"affiliations":[{"raw_affiliation_string":"Department of Clinical Nutrition, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","institution_ids":["https://openalex.org/I4210165501"]},{"raw_affiliation_string":"Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Clinical Nutrition, , Tianjin, 300110, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079264521","display_name":"Chenchao Jiang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210142182","display_name":"Tianjin Hospital","ror":"https://ror.org/04j9yn198","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142182"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chenchao Jiang","raw_affiliation_strings":["Department of Pharmacy, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Pharmacy, , Tianjin, 300110, China"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","institution_ids":["https://openalex.org/I4210142182"]},{"raw_affiliation_string":"Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Pharmacy, , Tianjin, 300110, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102990086","display_name":"Runhui Liu","orcid":"https://orcid.org/0000-0001-7489-4957"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Runhui Liu","raw_affiliation_strings":["Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China"],"affiliations":[{"raw_affiliation_string":"Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China","institution_ids":["https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108582491","display_name":"Wei Yang","orcid":"https://orcid.org/0009-0001-3034-7836"},"institutions":[{"id":"https://openalex.org/I4210142182","display_name":"Tianjin Hospital","ror":"https://ror.org/04j9yn198","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210142182"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Yang","raw_affiliation_strings":["Department of Pharmacy, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Pharmacy, , Tianjin, 300110, China"],"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Tianjin Rehabilitation Center of Joint Logistics Support Force , Tianjin 300110, China","institution_ids":["https://openalex.org/I4210142182"]},{"raw_affiliation_string":"Tianjin Rehabilitation Center of Joint Logistics Support Force Department of Pharmacy, , Tianjin, 300110, China","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035316822","display_name":"Sai Tian","orcid":"https://orcid.org/0000-0003-2498-190X"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I18452120","display_name":"Yantai University","ror":"https://ror.org/01rp41m56","country_code":"CN","type":"education","lineage":["https://openalex.org/I18452120"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Saisai Tian","raw_affiliation_strings":["Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University , Yantai 264005, China","Yantai University Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, , Yantai, 264005, China","Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China"],"affiliations":[{"raw_affiliation_string":"Department of Phytochemistry, School of Pharmacy, Second Military Medical University , Shanghai 200433, China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Yantai University , Yantai 264005, China","institution_ids":["https://openalex.org/I18452120"]},{"raw_affiliation_string":"Yantai University Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, , Yantai, 264005, China","institution_ids":["https://openalex.org/I18452120"]},{"raw_affiliation_string":"Second Military Medical University Department of Phytochemistry, School of Pharmacy, , Shanghai, 200433, China","institution_ids":["https://openalex.org/I177933477"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5110384966"],"corresponding_institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210142182"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.4579,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.64295463,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"40","issue":"9","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9947999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9929999709129333,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/repurposing","display_name":"Repurposing","score":0.7210767865180969},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6632370948791504},{"id":"https://openalex.org/keywords/signature","display_name":"Signature (topology)","score":0.6531843543052673},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.6300229430198669},{"id":"https://openalex.org/keywords/drug-repositioning","display_name":"Drug repositioning","score":0.6219990849494934},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.6067308187484741},{"id":"https://openalex.org/keywords/web-server","display_name":"Web server","score":0.5313482880592346},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4111268222332001},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.35758745670318604},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.32158130407333374},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.29905441403388977},{"id":"https://openalex.org/keywords/the-internet","display_name":"The Internet","score":0.14987409114837646},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.13858070969581604},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.10557210445404053},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.08329707384109497},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.07168292999267578}],"concepts":[{"id":"https://openalex.org/C519536355","wikidata":"https://www.wikidata.org/wiki/Q21021151","display_name":"Repurposing","level":2,"score":0.7210767865180969},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6632370948791504},{"id":"https://openalex.org/C2779696439","wikidata":"https://www.wikidata.org/wiki/Q7512811","display_name":"Signature (topology)","level":2,"score":0.6531843543052673},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.6300229430198669},{"id":"https://openalex.org/C103637391","wikidata":"https://www.wikidata.org/wiki/Q5308921","display_name":"Drug repositioning","level":3,"score":0.6219990849494934},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.6067308187484741},{"id":"https://openalex.org/C11392498","wikidata":"https://www.wikidata.org/wiki/Q11288","display_name":"Web server","level":3,"score":0.5313482880592346},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4111268222332001},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35758745670318604},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.32158130407333374},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29905441403388977},{"id":"https://openalex.org/C110875604","wikidata":"https://www.wikidata.org/wiki/Q75","display_name":"The Internet","level":2,"score":0.14987409114837646},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.13858070969581604},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.10557210445404053},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08329707384109497},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07168292999267578},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D058492","descriptor_name":"Drug Repositioning","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btae536","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae536","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae536/58979114/btae536.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:39213324","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39213324","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11398873","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11398873","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11398873/pdf/btae536.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btae536","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btae536","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btae536/58979114/btae536.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5400000214576721}],"awards":[{"id":"https://openalex.org/G1276829693","display_name":null,"funder_award_id":"Shanghai","funder_id":"https://openalex.org/F4320321881","funder_display_name":"Shanghai Municipal Education Commission"},{"id":"https://openalex.org/G7169906910","display_name":null,"funder_award_id":"2022YFC3502000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8764071032","display_name":null,"funder_award_id":"2022YFC","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321659","display_name":"Shanghai Education Development Foundation","ror":"https://ror.org/02kq92y46"},{"id":"https://openalex.org/F4320321881","display_name":"Shanghai Municipal Education Commission","ror":"https://ror.org/05tewj457"},{"id":"https://openalex.org/F4320322841","display_name":"Universidade de Macau","ror":"https://ror.org/01r4q9n85"},{"id":"https://openalex.org/F4320325599","display_name":"University of Science and Technology of China","ror":"https://ror.org/04c4dkn09"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320338247","display_name":"Moonshot Research and Development Program","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402100103.pdf","grobid_xml":"https://content.openalex.org/works/W4402100103.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W2039936465","https://openalex.org/W2107118079","https://openalex.org/W2108068107","https://openalex.org/W2121604817","https://openalex.org/W2130410032","https://openalex.org/W2146511318","https://openalex.org/W2167778120","https://openalex.org/W2404118507","https://openalex.org/W2604527271","https://openalex.org/W2612467560","https://openalex.org/W2793518816","https://openalex.org/W2990827591","https://openalex.org/W3012416987","https://openalex.org/W3039977092","https://openalex.org/W3093286766","https://openalex.org/W3102695902","https://openalex.org/W3133590568","https://openalex.org/W3161748363","https://openalex.org/W4220734682","https://openalex.org/W4226172846","https://openalex.org/W4318671044","https://openalex.org/W4320180775","https://openalex.org/W4387478341","https://openalex.org/W4398762762","https://openalex.org/W6713273039"],"related_works":["https://openalex.org/W2899096130","https://openalex.org/W3190782215","https://openalex.org/W2902729297","https://openalex.org/W3110500039","https://openalex.org/W4255531208","https://openalex.org/W4396858017","https://openalex.org/W4400165188","https://openalex.org/W4206422705","https://openalex.org/W4320009247","https://openalex.org/W3186872001"],"abstract_inverted_index":{"SSP":[0,9,23],"is":[1,10],"free":[2],"at":[3],"https://web.biotcm.net/SSP/.":[4],"The":[5],"current":[6],"version":[7],"of":[8],"archived":[11],"in":[12],"https://doi.org/10.6084/m9.figshare.26524741.v1,":[13],"allowing":[14],"users":[15],"to":[16],"directly":[17],"use":[18],"or":[19],"customize":[20],"their":[21],"own":[22],"webserver.":[24]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}