{"id":"https://openalex.org/W4383619017","doi":"https://doi.org/10.1093/bioinformatics/btad420","title":"LSMMD-MA: scaling multimodal data integration for single-cell genomics data analysis","display_name":"LSMMD-MA: scaling multimodal data integration for single-cell genomics data analysis","publication_year":2023,"publication_date":"2023-07-01","ids":{"openalex":"https://openalex.org/W4383619017","doi":"https://doi.org/10.1093/bioinformatics/btad420","pmid":"https://pubmed.ncbi.nlm.nih.gov/37421399"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btad420","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad420","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad420/50842164/btad420.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad420/50842164/btad420.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025022663","display_name":"Laetitia Meng-Papaxanthos","orcid":"https://orcid.org/0000-0002-0521-621X"},"institutions":[{"id":"https://openalex.org/I4210100430","display_name":"Google (Switzerland)","ror":"https://ror.org/014f9c269","country_code":"CH","type":"company","lineage":["https://openalex.org/I1291425158","https://openalex.org/I4210100430","https://openalex.org/I4210128969"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Laetitia Meng-Papaxanthos","raw_affiliation_strings":["Google Research, Brain Team, Google , Brandschenkestrasse 110 , Zurich 8002, Switzerland"],"affiliations":[{"raw_affiliation_string":"Google Research, Brain Team, Google , Brandschenkestrasse 110 , Zurich 8002, Switzerland","institution_ids":["https://openalex.org/I4210100430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090458052","display_name":"Ran Zhang","orcid":"https://orcid.org/0000-0002-7630-1251"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ran Zhang","raw_affiliation_strings":["Department of Genome Sciences, University of Washington , 3720 15th Ave NE , Seattle, WA 98195, United States","eScience Institute, University of Washington , 3910 15th Ave NE , Seattle, WA 98195, United States"],"affiliations":[{"raw_affiliation_string":"Department of Genome Sciences, University of Washington , 3720 15th Ave NE , Seattle, WA 98195, United States","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"eScience Institute, University of Washington , 3910 15th Ave NE , Seattle, WA 98195, United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100438758","display_name":"Gang Li","orcid":"https://orcid.org/0000-0003-0759-9063"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gang Li","raw_affiliation_strings":["Department of Genome Sciences, University of Washington , 3720 15th Ave NE , Seattle, WA 98195, United States","eScience Institute, University of Washington , 3910 15th Ave NE , Seattle, WA 98195, United States"],"affiliations":[{"raw_affiliation_string":"Department of Genome Sciences, University of Washington , 3720 15th Ave NE , Seattle, WA 98195, United States","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"eScience Institute, University of Washington , 3910 15th Ave NE , Seattle, WA 98195, United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017263427","display_name":"Marco Cuturi","orcid":"https://orcid.org/0000-0002-1934-0588"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marco Cuturi","raw_affiliation_strings":["Apple ML Research, Apple , 7 Av. d\u2019I\u00e9na , Paris 75116, France","Google Research, Brain Team, Google , 8 Rue de Londres , Paris 75009, France"],"affiliations":[{"raw_affiliation_string":"Apple ML Research, Apple , 7 Av. d\u2019I\u00e9na , Paris 75116, France","institution_ids":[]},{"raw_affiliation_string":"Google Research, Brain Team, Google , 8 Rue de Londres , Paris 75009, France","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057375933","display_name":"William Stafford Noble","orcid":"https://orcid.org/0000-0001-7283-4715"},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Stafford Noble","raw_affiliation_strings":["Department of Genome Sciences, University of Washington , 3720 15th Ave NE , Seattle, WA 98195, United States","Paul G. Allen School of Computer Science and Engineering, University of Washington , 185 E Stevens Way NE , Seattle, WA 98195, United States"],"affiliations":[{"raw_affiliation_string":"Department of Genome Sciences, University of Washington , 3720 15th Ave NE , Seattle, WA 98195, United States","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Paul G. Allen School of Computer Science and Engineering, University of Washington , 185 E Stevens Way NE , Seattle, WA 98195, United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064770739","display_name":"Jean\u2010Philippe Vert","orcid":"https://orcid.org/0000-0001-9510-8441"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean-Philippe Vert","raw_affiliation_strings":["Google Research, Brain Team, Google , 8 Rue de Londres , Paris 75009, France","Owkin, Inc. , 14/16 Bd Poissonni\u00e8re , Paris 75009, France"],"affiliations":[{"raw_affiliation_string":"Google Research, Brain Team, Google , 8 Rue de Londres , Paris 75009, France","institution_ids":[]},{"raw_affiliation_string":"Owkin, Inc. , 14/16 Bd Poissonni\u00e8re , Paris 75009, France","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5025022663"],"corresponding_institution_ids":["https://openalex.org/I4210100430"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.4618,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.66911873,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"39","issue":"7","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9128000140190125,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6533271074295044},{"id":"https://openalex.org/keywords/scaling","display_name":"Scaling","score":0.5709248185157776},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.5579894781112671},{"id":"https://openalex.org/keywords/data-integration","display_name":"Data integration","score":0.5129215717315674},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.4501287639141083},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4268525540828705},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3244893550872803},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20796364545822144},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.19847318530082703},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15574166178703308},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.10784992575645447},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.08209443092346191},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.07581180334091187}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6533271074295044},{"id":"https://openalex.org/C99844830","wikidata":"https://www.wikidata.org/wiki/Q102441924","display_name":"Scaling","level":2,"score":0.5709248185157776},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.5579894781112671},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.5129215717315674},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4501287639141083},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4268525540828705},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3244893550872803},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20796364545822144},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.19847318530082703},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15574166178703308},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.10784992575645447},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.08209443092346191},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07581180334091187},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000078332","descriptor_name":"Data Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000078332","descriptor_name":"Data Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000078332","descriptor_name":"Data Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000078332","descriptor_name":"Data Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012107","descriptor_name":"Research Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016678","descriptor_name":"Genome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023281","descriptor_name":"Genomics","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btad420","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad420","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad420/50842164/btad420.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:37421399","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37421399","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:10336029","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10336029","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10336029/pdf/btad420.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btad420","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btad420","pdf_url":"https://academic.oup.com/bioinformatics/advance-article-pdf/doi/10.1093/bioinformatics/btad420/50842164/btad420.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2563204906","display_name":null,"funder_award_id":"UM1 HG011531","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4383619017.pdf"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W2032618685","https://openalex.org/W2948469692","https://openalex.org/W2978997241","https://openalex.org/W2982521190","https://openalex.org/W3012788672","https://openalex.org/W3020430839","https://openalex.org/W3043558371","https://openalex.org/W3092493138","https://openalex.org/W3101592465","https://openalex.org/W3113863876","https://openalex.org/W3125524953","https://openalex.org/W3128617908","https://openalex.org/W3129866267","https://openalex.org/W3164692211","https://openalex.org/W4212774754","https://openalex.org/W4225278475","https://openalex.org/W4226403813","https://openalex.org/W6688325169","https://openalex.org/W6769775530","https://openalex.org/W6776608806"],"related_works":["https://openalex.org/W141820298","https://openalex.org/W2049584446","https://openalex.org/W2079781215","https://openalex.org/W4378770497","https://openalex.org/W4308245303","https://openalex.org/W2014033564","https://openalex.org/W2910573937","https://openalex.org/W4385571583","https://openalex.org/W4389519396","https://openalex.org/W2113438243"],"abstract_inverted_index":{"LSMMD-MA":[0],"is":[1],"freely":[2],"available":[3],"at":[4,8],"https://github.com/google-research/large_scale_mmdma":[5],"and":[6],"archived":[7],"https://doi.org/10.5281/zenodo.8076311.":[9]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}