{"id":"https://openalex.org/W3123399939","doi":"https://doi.org/10.1093/bioinformatics/btab001","title":"Compression of quantification uncertainty for scRNA-seq counts","display_name":"Compression of quantification uncertainty for scRNA-seq counts","publication_year":2021,"publication_date":"2021-01-04","ids":{"openalex":"https://openalex.org/W3123399939","doi":"https://doi.org/10.1093/bioinformatics/btab001","mag":"3123399939","pmid":"https://pubmed.ncbi.nlm.nih.gov/33471073"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btab001","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab001","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1093/bioinformatics/btab001","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064212161","display_name":"Scott Van Buren","orcid":"https://orcid.org/0000-0002-5722-4342"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott Van Buren","raw_affiliation_strings":["Department of Biostatistics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27516, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27516, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040245011","display_name":"Hirak Sarkar","orcid":"https://orcid.org/0000-0003-3636-7384"},"institutions":[{"id":"https://openalex.org/I66946132","display_name":"University of Maryland, College Park","ror":"https://ror.org/047s2c258","country_code":"US","type":"education","lineage":["https://openalex.org/I66946132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hirak Sarkar","raw_affiliation_strings":["Center for Bioinformatics and Computational Biology, University of Maryland , College Park, MD 20742, USA","Department of Computer Science, University of Maryland , College Park, MD 20742, USA"],"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics and Computational Biology, University of Maryland , College Park, MD 20742, USA","institution_ids":["https://openalex.org/I66946132"]},{"raw_affiliation_string":"Department of Computer Science, University of Maryland , College Park, MD 20742, USA","institution_ids":["https://openalex.org/I66946132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085346602","display_name":"Avi Srivastava","orcid":"https://orcid.org/0000-0001-9798-2079"},"institutions":[{"id":"https://openalex.org/I4210151462","display_name":"New York Genome Center","ror":"https://ror.org/05wf2ga96","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210151462"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Avi Srivastava","raw_affiliation_strings":["Center for Genomics and Systems Biology, New York University , New York, NY 10003, USA","New York Genome Center , New York, NY 10013, USA"],"affiliations":[{"raw_affiliation_string":"Center for Genomics and Systems Biology, New York University , New York, NY 10003, USA","institution_ids":["https://openalex.org/I57206974"]},{"raw_affiliation_string":"New York Genome Center , New York, NY 10013, USA","institution_ids":["https://openalex.org/I4210151462"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065665275","display_name":"Naim U. Rashid","orcid":"https://orcid.org/0000-0002-7274-8259"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Naim U Rashid","raw_affiliation_strings":["Department of Biostatistics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27516, USA","Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27516, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014584023","display_name":"Rob Patro","orcid":"https://orcid.org/0000-0001-8463-1675"},"institutions":[{"id":"https://openalex.org/I66946132","display_name":"University of Maryland, College Park","ror":"https://ror.org/047s2c258","country_code":"US","type":"education","lineage":["https://openalex.org/I66946132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rob Patro","raw_affiliation_strings":["Center for Bioinformatics and Computational Biology, University of Maryland , College Park, MD 20742, USA","Department of Computer Science, University of Maryland , College Park, MD 20742, USA"],"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics and Computational Biology, University of Maryland , College Park, MD 20742, USA","institution_ids":["https://openalex.org/I66946132"]},{"raw_affiliation_string":"Department of Computer Science, University of Maryland , College Park, MD 20742, USA","institution_ids":["https://openalex.org/I66946132"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049770701","display_name":"Michael I. Love","orcid":"https://orcid.org/0000-0001-8401-0545"},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Michael I Love","raw_affiliation_strings":["Department of Biostatistics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27516, USA","Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27514, USA"],"affiliations":[{"raw_affiliation_string":"Department of Biostatistics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27516, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Genetics, University of North Carolina at Chapel Hill , Chapel Hill, NC 27514, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5049770701"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":{"value":3618,"currency":"USD","value_usd":3618},"fwci":0.3254,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.54870561,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"37","issue":"12","first_page":"1699","last_page":"1707"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9825000166893005,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bioconductor","display_name":"Bioconductor","score":0.8816468715667725},{"id":"https://openalex.org/keywords/false-positive-paradox","display_name":"False positive paradox","score":0.6844418048858643},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6725844144821167},{"id":"https://openalex.org/keywords/negative-binomial-distribution","display_name":"Negative binomial distribution","score":0.5394234657287598},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4798421561717987},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4643336534500122},{"id":"https://openalex.org/keywords/variance","display_name":"Variance (accounting)","score":0.45874911546707153},{"id":"https://openalex.org/keywords/binomial-distribution","display_name":"Binomial distribution","score":0.41218283772468567},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.31194043159484863},{"id":"https://openalex.org/keywords/poisson-distribution","display_name":"Poisson distribution","score":0.22963979840278625},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.18742096424102783},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.16898375749588013},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.14289066195487976},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.11778968572616577}],"concepts":[{"id":"https://openalex.org/C2779694297","wikidata":"https://www.wikidata.org/wiki/Q2888953","display_name":"Bioconductor","level":3,"score":0.8816468715667725},{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.6844418048858643},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6725844144821167},{"id":"https://openalex.org/C199335787","wikidata":"https://www.wikidata.org/wiki/Q743364","display_name":"Negative binomial distribution","level":3,"score":0.5394234657287598},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4798421561717987},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4643336534500122},{"id":"https://openalex.org/C196083921","wikidata":"https://www.wikidata.org/wiki/Q7915758","display_name":"Variance (accounting)","level":2,"score":0.45874911546707153},{"id":"https://openalex.org/C41054675","wikidata":"https://www.wikidata.org/wiki/Q185547","display_name":"Binomial distribution","level":2,"score":0.41218283772468567},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.31194043159484863},{"id":"https://openalex.org/C100906024","wikidata":"https://www.wikidata.org/wiki/Q205692","display_name":"Poisson distribution","level":2,"score":0.22963979840278625},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.18742096424102783},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16898375749588013},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.14289066195487976},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11778968572616577},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C121955636","wikidata":"https://www.wikidata.org/wiki/Q4116214","display_name":"Accounting","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btab001","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab001","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33471073","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33471073","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8289386","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8289386","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btab001","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btab001","pdf_url":null,"source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3037030683","display_name":null,"funder_award_id":"P30 CA016086","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3184792579","display_name":null,"funder_award_id":"CCF-1750472","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6262999909","display_name":null,"funder_award_id":"R01 HG009937","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6785428991","display_name":null,"funder_award_id":"CNS-1763680","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7467572168","display_name":null,"funder_award_id":"P50 CA058223","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W25132263","https://openalex.org/W1538685017","https://openalex.org/W1579303078","https://openalex.org/W1980836133","https://openalex.org/W1985710418","https://openalex.org/W1999574084","https://openalex.org/W2036895652","https://openalex.org/W2043266302","https://openalex.org/W2045656233","https://openalex.org/W2080793044","https://openalex.org/W2082028069","https://openalex.org/W2096465161","https://openalex.org/W2097392849","https://openalex.org/W2099879295","https://openalex.org/W2103750788","https://openalex.org/W2105381419","https://openalex.org/W2110417468","https://openalex.org/W2129916363","https://openalex.org/W2157160484","https://openalex.org/W2157355630","https://openalex.org/W2166163519","https://openalex.org/W2169456326","https://openalex.org/W2197124664","https://openalex.org/W2318878471","https://openalex.org/W2323326409","https://openalex.org/W2334043242","https://openalex.org/W2526724898","https://openalex.org/W2592811885","https://openalex.org/W2620721366","https://openalex.org/W2624530800","https://openalex.org/W2737913489","https://openalex.org/W2793580068","https://openalex.org/W2809616137","https://openalex.org/W2886347923","https://openalex.org/W2898598946","https://openalex.org/W2912272542","https://openalex.org/W2915489249","https://openalex.org/W2927507212","https://openalex.org/W2944073176","https://openalex.org/W2949067670","https://openalex.org/W2951506174","https://openalex.org/W2951799803","https://openalex.org/W2954555796","https://openalex.org/W2964916138","https://openalex.org/W3005127469","https://openalex.org/W3007273059","https://openalex.org/W3009370296","https://openalex.org/W3011205690","https://openalex.org/W3043726824","https://openalex.org/W3102089015","https://openalex.org/W4232909036","https://openalex.org/W4248681815","https://openalex.org/W4364356387","https://openalex.org/W6684823039","https://openalex.org/W6684826817"],"related_works":["https://openalex.org/W3163106361","https://openalex.org/W2152239989","https://openalex.org/W2037403216","https://openalex.org/W1981794870","https://openalex.org/W1602555103","https://openalex.org/W120285656","https://openalex.org/W2887966696","https://openalex.org/W2052110748","https://openalex.org/W4244236455","https://openalex.org/W62389518"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}