{"id":"https://openalex.org/W3115208483","doi":"https://doi.org/10.1093/bioinformatics/btaa816","title":"SCHNEL: scalable clustering of high dimensional single-cell data","display_name":"SCHNEL: scalable clustering of high dimensional single-cell data","publication_year":2020,"publication_date":"2020-09-07","ids":{"openalex":"https://openalex.org/W3115208483","doi":"https://doi.org/10.1093/bioinformatics/btaa816","mag":"3115208483","pmid":"https://pubmed.ncbi.nlm.nih.gov/33381821"},"language":"en","primary_location":{"id":"doi:10.1093/bioinformatics/btaa816","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa816","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_2/i849/35336913/btaa816.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_2/i849/35336913/btaa816.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027121672","display_name":"Tamim Abdelaal","orcid":"https://orcid.org/0000-0003-2719-5736"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Tamim Abdelaal","raw_affiliation_strings":["Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","Leiden Computational Biology Center"],"affiliations":[{"raw_affiliation_string":"Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Leiden Computational Biology Center","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045293081","display_name":"Paul de Raadt","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul de Raadt","raw_affiliation_strings":["Leiden Computational Biology Center"],"affiliations":[{"raw_affiliation_string":"Leiden Computational Biology Center","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019003563","display_name":"Boudewijn P. F. Lelieveldt","orcid":"https://orcid.org/0000-0001-8269-7603"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Boudewijn P F Lelieveldt","raw_affiliation_strings":["Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","Leiden Computational Biology Center"],"affiliations":[{"raw_affiliation_string":"Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Leiden Computational Biology Center","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052699801","display_name":"Marcel Reinders","orcid":"https://orcid.org/0000-0002-1148-1562"},"institutions":[{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marcel J T Reinders","raw_affiliation_strings":["Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","Department of Human Genetics, Leiden University Medical Center , 2333 ZC Leiden, The Netherlands","Leiden Computational Biology Center"],"affiliations":[{"raw_affiliation_string":"Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Department of Human Genetics, Leiden University Medical Center , 2333 ZC Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]},{"raw_affiliation_string":"Leiden Computational Biology Center","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006562407","display_name":"Ahmed Mahfouz","orcid":"https://orcid.org/0000-0001-8601-2149"},"institutions":[{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]},{"id":"https://openalex.org/I98358874","display_name":"Delft University of Technology","ror":"https://ror.org/02e2c7k09","country_code":"NL","type":"education","lineage":["https://openalex.org/I98358874"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"Ahmed Mahfouz","raw_affiliation_strings":["Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","Department of Human Genetics, Leiden University Medical Center , 2333 ZC Leiden, The Netherlands","Leiden Computational Biology Center"],"affiliations":[{"raw_affiliation_string":"Delft Bioinformatics Lab, Delft University of Technology , 2628 XE Delft, The Netherlands","institution_ids":["https://openalex.org/I98358874"]},{"raw_affiliation_string":"Department of Human Genetics, Leiden University Medical Center , 2333 ZC Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]},{"raw_affiliation_string":"Leiden Computational Biology Center","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5006562407"],"corresponding_institution_ids":["https://openalex.org/I2800006345","https://openalex.org/I98358874"],"apc_list":{"value":3618,"currency":"USD","value_usd":3618},"apc_paid":null,"fwci":0.3335,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.58447829,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"36","issue":"Supplement_2","first_page":"i849","last_page":"i856"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9858999848365784,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7415332794189453},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6959332823753357},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.6146985292434692},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3857528567314148},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2182134985923767},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.1617191731929779}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7415332794189453},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6959332823753357},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.6146985292434692},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3857528567314148},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2182134985923767},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.1617191731929779}],"mesh":[{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000073359","descriptor_name":"Exome Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016000","descriptor_name":"Cluster Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bioinformatics/btaa816","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa816","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_2/i849/35336913/btaa816.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33381821","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33381821","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics (Oxford, England)","raw_type":null},{"id":"pmh:lumc:oai:scholarlypublications.universiteitleiden.nl:item_3184427","is_oa":true,"landing_page_url":"https://academic.oup.com/bioinformatics/article/36/Supplement_2/i849/6055909","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bioinformatics, 36, I849 - I856. OXFORD UNIV PRESS","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1093/bioinformatics/btaa816","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bioinformatics/btaa816","pdf_url":"https://academic.oup.com/bioinformatics/article-pdf/36/Supplement_2/i849/35336913/btaa816.pdf","source":{"id":"https://openalex.org/S52395412","display_name":"Bioinformatics","issn_l":"1367-4803","issn":["1367-4803","1367-4811"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321800","display_name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","ror":"https://ror.org/04jsz6e67"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3115208483.pdf","grobid_xml":"https://content.openalex.org/works/W3115208483.grobid-xml"},"referenced_works_count":42,"referenced_works":["https://openalex.org/W1561150462","https://openalex.org/W1607921872","https://openalex.org/W1618915084","https://openalex.org/W1631320694","https://openalex.org/W1810935231","https://openalex.org/W1845511091","https://openalex.org/W1875842236","https://openalex.org/W1993835819","https://openalex.org/W2025886100","https://openalex.org/W2033403400","https://openalex.org/W2038254572","https://openalex.org/W2047594345","https://openalex.org/W2070503238","https://openalex.org/W2112493011","https://openalex.org/W2131681506","https://openalex.org/W2138615112","https://openalex.org/W2151936673","https://openalex.org/W2161754737","https://openalex.org/W2165111228","https://openalex.org/W2187089797","https://openalex.org/W2255388164","https://openalex.org/W2346039638","https://openalex.org/W2358421111","https://openalex.org/W2387281789","https://openalex.org/W2464824038","https://openalex.org/W2467197661","https://openalex.org/W2498761000","https://openalex.org/W2522948376","https://openalex.org/W2573505039","https://openalex.org/W2624819889","https://openalex.org/W2766011162","https://openalex.org/W2768365920","https://openalex.org/W2897249806","https://openalex.org/W2905272079","https://openalex.org/W2949693884","https://openalex.org/W2951566836","https://openalex.org/W2969775576","https://openalex.org/W2983201012","https://openalex.org/W3099768174","https://openalex.org/W3105265400","https://openalex.org/W3106188259","https://openalex.org/W6680970901"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2389214306"],"abstract_inverted_index":{"Supplementary":[0],"data":[1],"are":[2],"available":[3],"at":[4],"Bioinformatics":[5],"online.":[6]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-03-10T16:38:18.471706","created_date":"2025-10-10T00:00:00"}